𝕏

Task 55145705

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_594_0
Workunit 26186479
Created 28 Jun 2024, 5:34:44 UTC
Sent 28 Jun 2024, 18:15:46 UTC
Report deadline 1 Jul 2024, 18:15:46 UTC
Received 29 Jun 2024, 14:35:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 52 min 17 sec
CPU time 1 hours 25 min 58 sec
Validate state Valid
Credit 42.09
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.89 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_594.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_594_0_r1974450637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_594_0_r1974450637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.409547
     * GNaL_b in INaL: 0.005805
     * Gto_b in Ito: 0.091227
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031296
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.168240
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.017033
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020931
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8969900, states[0] = -86.995776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17743913, states[0] = -86.816626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26851750, states[0] = -86.883755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35631381, states[0] = -53.470929, states[40]= 0.000015
Saving checkpoint... 
Iteration: 43756022, states[0] = -86.765842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52079711, states[0] = -3.018984, states[40]= 0.003699
Saving checkpoint... 
Iteration: 60932480, states[0] = -86.861130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69239025, states[0] = -86.715481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77504636, states[0] = 26.124408, states[40]= 0.168506
Saving checkpoint... 
Iteration: 85821901, states[0] = -86.798867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94106144, states[0] = -25.951859, states[40]= 0.000636
Saving checkpoint... 
Iteration: 102905306, states[0] = -86.834549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110838665, states[0] = -86.803289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119421593, states[0] = -86.836433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127679530, states[0] = -86.571948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135253772, states[0] = -86.719704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143962977, states[0] = -86.843338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151581158, states[0] = -3.138335, states[40]= 0.003663
Saving checkpoint... 
Iteration: 159947530, states[0] = -86.839455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170055029, states[0] = 10.102747, states[40]= 0.004612
Saving checkpoint... 
Iteration: 177976438, states[0] = -86.844210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185891950, states[0] = -86.823127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194573461, states[0] = 1.581163, states[40]= 0.004298
Saving checkpoint... 
Iteration: 202318574, states[0] = -86.784265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210643830, states[0] = -64.500703, states[40]= 0.000002
Saving checkpoint... 
Iteration: 219843886, states[0] = -86.800606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227752853, states[0] = -86.715628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235750307, states[0] = -86.711933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244272801, states[0] = -86.741200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252933141, states[0] = -86.834821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261092574, states[0] = -12.441007, states[40]= 0.001829
Saving checkpoint... 
Iteration: 269155881, states[0] = -80.680128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277396954, states[0] = -86.824220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286369208, states[0] = -86.813251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295489478, states[0] = -86.845280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305489463, states[0] = -86.845262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313871859, states[0] = -86.814386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321885372, states[0] = -86.819930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331472489, states[0] = -86.842639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339217862, states[0] = -86.657037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347698872, states[0] = -86.618566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356319469, states[0] = -86.784398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364701244, states[0] = -86.623537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372191155, states[0] = -86.601956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380935659, states[0] = -86.835229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389471834, states[0] = -86.842472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398197979, states[0] = -86.616629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407749348, states[0] = -86.710236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415251359, states[0] = -86.713146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423171763, states[0] = -86.465943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432887959, states[0] = -86.820805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441516247, states[0] = 22.143143, states[40]= 0.011915
Saving checkpoint... 
Iteration: 450051174, states[0] = 11.663311, states[40]= 0.004601
Saving checkpoint... 
Iteration: 458229826, states[0] = -86.678865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466448099, states[0] = -86.837938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474530902, states[0] = 18.980082, states[40]= 0.005000
Saving checkpoint... 
Iteration: 484184318, states[0] = -86.585293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493309729, states[0] = -86.776802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503028957, states[0] = 19.558211, states[40]= 0.005166
Saving checkpoint... 
Iteration: 511007063, states[0] = 23.330813, states[40]= 0.097147
Saving checkpoint... 
Iteration: 519284531, states[0] = -86.753723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528245500, states[0] = -86.704390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536768721, states[0] = -86.735982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544751172, states[0] = -86.712762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553443519, states[0] = -86.836874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562053307, states[0] = 10.813821, states[40]= 0.004608
Saving checkpoint... 
Iteration: 569873474, states[0] = -86.814848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578025789, states[0] = 20.415975, states[40]= 0.005583
Saving checkpoint... 
Iteration: 586375308, states[0] = -86.815618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594552144, states[0] = 11.278798, states[40]= 0.004604
Saving checkpoint... 
Iteration: 602868570, states[0] = -86.812652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612623239, states[0] = -42.115860, states[40]= 0.000092
Saving checkpoint... 
Iteration: 620691518, states[0] = -86.602532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628629012, states[0] = -47.961188, states[40]= 0.000037
Saving checkpoint... 
Iteration: 637034165, states[0] = 17.938464, states[40]= 0.004809
Saving checkpoint... 
Iteration: 645370713, states[0] = -86.813574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654835387, states[0] = -86.794895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663449137, states[0] = -86.837982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673033622, states[0] = 18.117339, states[40]= 0.004835
Saving checkpoint... 
Iteration: 681766671, states[0] = -86.733343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689313325, states[0] = -86.779471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698270360, states[0] = -86.737809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706258165, states[0] = -86.722348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715665746, states[0] = -86.026730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724327503, states[0] = -86.789713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732445404, states[0] = -86.837128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739961571, states[0] = -86.840358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748394421, states[0] = -86.822880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757180359, states[0] = -86.571293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766798630, states[0] = -86.767115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776642198, states[0] = -62.463675, states[40]= 0.000003
Saving checkpoint... 
Iteration: 786270269, states[0] = -86.737622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794814147, states[0] = -86.780014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802413227, states[0] = -86.828907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810056596, states[0] = 9.473198, states[40]= 0.004615
Saving checkpoint... 
Iteration: 819316328, states[0] = -86.781654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827969561, states[0] = -86.841701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836034318, states[0] = 17.887769, states[40]= 0.004802
Saving checkpoint... 
Iteration: 844779223, states[0] = -86.747793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853027573, states[0] = 19.946824, states[40]= 0.005320
Saving checkpoint... 
Iteration: 861318928, states[0] = -86.783552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870009750, states[0] = 22.596294, states[40]= 0.048313
Saving checkpoint... 
Iteration: 878327471, states[0] = -86.789556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887101821, states[0] = -21.347817, states[40]= 0.000855
Saving checkpoint... 
Iteration: 894943754, states[0] = -86.836626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902629453, states[0] = -48.416397, states[40]= 0.000035
Saving checkpoint... 
Iteration: 911013304, states[0] = 22.365821, states[40]= 0.020614
Saving checkpoint... 
Iteration: 921226302, states[0] = -86.672203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930160993, states[0] = -84.683898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938750641, states[0] = -86.711646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948714906, states[0] = -86.650762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957880754, states[0] = -86.817541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966925312, states[0] = -86.832126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975566950, states[0] = 4.900406, states[40]= 0.004526
Saving checkpoint... 
Iteration: 984723875, states[0] = -86.667737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993574220, states[0] = 1.173879, states[40]= 0.004258
Saving checkpoint... 
Iteration: 1002416681, states[0] = -86.829732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010977299, states[0] = -86.842812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018945003, states[0] = -86.836790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027187881, states[0] = -86.593919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036751854, states[0] = -86.713303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046224322, states[0] = -86.668501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055955923, states[0] = -86.839007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065964436, states[0] = -86.840593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074511348, states[0] = 22.469570, states[40]= 0.032322
Saving checkpoint... 
Iteration: 1084011068, states[0] = 22.486337, states[40]= 0.034619
Saving checkpoint... 
Iteration: 1094021564, states[0] = 21.361234, states[40]= 0.006769
Saving checkpoint... 
Iteration: 1103230150, states[0] = -86.678856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111739152, states[0] = -86.693942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120022395, states[0] = 21.195792, states[40]= 0.006438
Saving checkpoint... 
Iteration: 1128906378, states[0] = -86.826532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137803366, states[0] = -86.770945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147698109, states[0] = -86.616234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157977836, states[0] = -86.842768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167420081, states[0] = -86.830541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176814507, states[0] = -86.779953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186497222, states[0] = -86.845514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196020442, states[0] = 21.567162, states[40]= 0.007338
Saving checkpoint... 
Iteration: 1205578863, states[0] = -1.578976, states[40]= 0.003914
Saving checkpoint... 
Iteration: 1215131479, states[0] = -50.526902, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1224128114, states[0] = -47.036729, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1233119485, states[0] = -38.418016, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1242640293, states[0] = -60.199040, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1252319481, states[0] = -86.783612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260803012, states[0] = -86.770532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270027000, states[0] = 20.101711, states[40]= 0.005395
Saving checkpoint... 
Iteration: 1278694429, states[0] = -86.608270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287117007, states[0] = -36.008156, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1296139236, states[0] = -58.978162, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1306389524, states[0] = -86.820619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315902174, states[0] = -86.825017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325577025, states[0] = -0.445013, states[40]= 0.004072
Saving checkpoint... 
Iteration: 1334081706, states[0] = -3.467847, states[40]= 0.003604
Saving checkpoint... 
Iteration: 1343132881, states[0] = -52.005977, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1352795644, states[0] = -86.763872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362890098, states[0] = -86.820781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371331710, states[0] = -86.791924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381594061, states[0] = -13.840396, states[40]= 0.001600
Saving checkpoint... 
Iteration: 1390488454, states[0] = -86.844148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400184475, states[0] = -86.584915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409044434, states[0] = 14.266148, states[40]= 0.004595
Saving checkpoint... 
Iteration: 1418513409, states[0] = 22.359997, states[40]= 0.020157
Saving checkpoint... 
Iteration: 1427402301, states[0] = -86.824961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437711527, states[0] = -86.643647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447864231, states[0] = -86.809902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457322692, states[0] = -86.785740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466551388, states[0] = 11.579095, states[40]= 0.004601
Saving checkpoint... 
Iteration: 1475311715, states[0] = -86.777517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484406638, states[0] = -86.826301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493738332, states[0] = -86.692277, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.721469
 - CaMKt in component CaMK (millimolar): 0.007231
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.465875
 - nass in component intracellular_ions (millimolar): 6.465933
 - ki in component intracellular_ions (millimolar): 145.510249
 - kss in component intracellular_ions (millimolar): 145.510230
 - cansr in component intracellular_ions (millimolar): 1.324358
 - cajsr in component intracellular_ions (millimolar): 1.285866
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.008249
 - hf in component INa (dimensionless): 0.656629
 - hs in component INa (dimensionless): 0.656616
 - j in component INa (dimensionless): 0.656549
 - hsp in component INa (dimensionless): 0.408396
 - jp in component INa (dimensionless): 0.656502
 - mL in component INaL (dimensionless): 0.000234
 - hL in component INaL (dimensionless): 0.461732
 - hLp in component INaL (dimensionless): 0.236926
 - a in component Ito (dimensionless): 0.001082
 - iF in component Ito (dimensionless): 0.999454
 - iS in component Ito (dimensionless): 0.575153
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999454
 - iSp in component Ito (dimensionless): 0.628964
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934586
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001644
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.404003
 - xs1 in component IKs (dimensionless): 0.244953
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997050
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:32:09 (2099): called boinc_finish(0)

</stderr_txt>
]]>


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