𝕏

Task 55137851

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387_1
Workunit 26182567
Created 28 Jun 2024, 5:31:08 UTC
Sent 28 Jun 2024, 17:20:54 UTC
Report deadline 1 Jul 2024, 17:20:54 UTC
Received 29 Jun 2024, 3:48:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228119
Run time 9 hours 8 min 29 sec
CPU time 8 hours 56 min 43 sec
Validate state Valid
Credit 41.71
Device peak FLOPS 1.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 11.14 MB
Peak disk usage 0.37 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387_1_r1628593356_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387_1_r1628593356_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 97.723621
     * GNaL_b in INaL: 0.006805
     * Gto_b in Ito: 0.082741
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032890
     * GKs_b in IKs: 0.002016
     * GK1_b in IK1: 0.173032
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 71.864706
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041273
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 2923278, states[0] = -95.058679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 5902037, states[0] = -95.022978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 8853726, states[0] = -94.973437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 11761801, states[0] = -94.843463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14710041, states[0] = -94.687424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17652869, states[0] = -70.966920, states[40]= 0.000003
Saving checkpoint... 
Iteration: 20592781, states[0] = -6.451392, states[40]= 0.003380
Saving checkpoint... 
Iteration: 23538016, states[0] = 21.785034, states[40]= 0.002159
Saving checkpoint... 
Iteration: 26467319, states[0] = -94.965529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29406158, states[0] = -94.940633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32359868, states[0] = -94.909863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35279455, states[0] = -94.811188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38216256, states[0] = -94.645197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41140945, states[0] = -53.842824, states[40]= 0.000049
Saving checkpoint... 
Iteration: 44086991, states[0] = -1.298355, states[40]= 0.004311
Saving checkpoint... 
Iteration: 47028076, states[0] = 25.235603, states[40]= 0.001568
Saving checkpoint... 
Iteration: 49967929, states[0] = -94.951766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52891731, states[0] = -94.921559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55838602, states[0] = -94.881705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58760100, states[0] = -94.763075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61675738, states[0] = -94.134400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64638218, states[0] = -50.432045, states[40]= 0.000083
Saving checkpoint... 
Iteration: 67574561, states[0] = 6.443006, states[40]= 0.004460
Saving checkpoint... 
Iteration: 70508526, states[0] = 28.106262, states[40]= 0.078544
Saving checkpoint... 
Iteration: 73443469, states[0] = -94.940811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76376532, states[0] = -94.908986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79304033, states[0] = -94.838564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82222226, states[0] = -94.654925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85171425, states[0] = -93.082536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88108488, states[0] = -20.679283, states[40]= 0.001240
Saving checkpoint... 
Iteration: 91057472, states[0] = 14.489556, states[40]= 0.003354
Saving checkpoint... 
Iteration: 93992645, states[0] = -94.951966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96944425, states[0] = -94.939432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99889033, states[0] = -94.915059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102825080, states[0] = -94.863251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105764499, states[0] = -94.768552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108690564, states[0] = -94.527110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111631177, states[0] = -42.726133, states[40]= 0.000246
Saving checkpoint... 
Iteration: 114568308, states[0] = 9.659543, states[40]= 0.004149
Saving checkpoint... 
Iteration: 117510078, states[0] = 27.961901, states[40]= 0.046766
Saving checkpoint... 
Iteration: 120443251, states[0] = -94.938192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123378942, states[0] = -94.908196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126295179, states[0] = -94.823546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129237000, states[0] = -94.699221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132166926, states[0] = -89.495425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135103815, states[0] = -15.998380, states[40]= 0.001583
Saving checkpoint... 
Iteration: 138044547, states[0] = 19.642494, states[40]= 0.002367
Saving checkpoint... 
Iteration: 140953069, states[0] = -94.940855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143899115, states[0] = -94.919360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146841150, states[0] = -94.878523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149789732, states[0] = -94.814587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152730557, states[0] = -94.679549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155650213, states[0] = -63.926375, states[40]= 0.000010
Saving checkpoint... 
Iteration: 158568174, states[0] = 9.736137, states[40]= 0.004144
Saving checkpoint... 
Iteration: 161493160, states[0] = -94.950377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164438328, states[0] = -94.935817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167367406, states[0] = -94.899779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170281611, states[0] = -94.800628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173219698, states[0] = -94.643718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176149061, states[0] = -62.500979, states[40]= 0.000012
Saving checkpoint... 
Iteration: 179050156, states[0] = 17.484688, states[40]= 0.002781
Saving checkpoint... 
Iteration: 181991796, states[0] = -94.949930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184910601, states[0] = -94.924542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187851331, states[0] = -94.887162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190796598, states[0] = -94.824919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193736083, states[0] = -94.695825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196684780, states[0] = -94.483595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199617759, states[0] = -29.492093, states[40]= 0.000983
Saving checkpoint... 
Iteration: 202550020, states[0] = 17.539103, states[40]= 0.002771
Saving checkpoint... 
Iteration: 205493813, states[0] = -94.950178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208443988, states[0] = -94.937412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211374525, states[0] = -94.904372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214298155, states[0] = -94.827101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217237187, states[0] = -94.698898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220150399, states[0] = -64.139583, states[40]= 0.000009
Saving checkpoint... 
Iteration: 223049209, states[0] = 17.857229, states[40]= 0.002709
Saving checkpoint... 
Iteration: 225984799, states[0] = -94.948231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228908664, states[0] = -94.923396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231828305, states[0] = -94.865038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234765653, states[0] = -94.769381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237705086, states[0] = -94.589037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240654809, states[0] = -69.998480, states[40]= 0.000004
Saving checkpoint... 
Iteration: 243605269, states[0] = -17.416250, states[40]= 0.001436
Saving checkpoint... 
Iteration: 246541138, states[0] = 20.919375, states[40]= 0.002143
Saving checkpoint... 
Iteration: 249463473, states[0] = -94.942999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252383832, states[0] = -94.910062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255338471, states[0] = -94.875246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258268000, states[0] = -94.774164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261203529, states[0] = -94.582716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264156380, states[0] = -72.303982, states[40]= 0.000003
Saving checkpoint... 
Iteration: 267090461, states[0] = -3.651375, states[40]= 0.003980
Saving checkpoint... 
Iteration: 270028198, states[0] = 25.278227, states[40]= 0.001581
Saving checkpoint... 
Iteration: 272970660, states[0] = -94.944757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275912763, states[0] = -94.925074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278862226, states[0] = -94.895384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281815027, states[0] = -94.849574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284733958, states[0] = -94.689114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287668755, states[0] = -91.334998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290605221, states[0] = -17.367957, states[40]= 0.001440
Saving checkpoint... 
Iteration: 293536674, states[0] = 22.525442, states[40]= 0.001885
Saving checkpoint... 
Iteration: 296483974, states[0] = -94.947752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299429717, states[0] = -94.931981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302369671, states[0] = -94.900676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305278509, states[0] = -94.794361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308233868, states[0] = -94.688749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311165988, states[0] = -88.226092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314121283, states[0] = -32.869124, states[40]= 0.000767
Saving checkpoint... 
Iteration: 317074017, states[0] = 6.810556, states[40]= 0.004450
Saving checkpoint... 
Iteration: 319994293, states[0] = -94.949772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322931303, states[0] = -94.932484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325847284, states[0] = -94.883054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328784892, states[0] = -94.805547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331721837, states[0] = -94.650281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334640431, states[0] = -52.579206, states[40]= 0.000060
Saving checkpoint... 
Iteration: 337592987, states[0] = -5.725891, states[40]= 0.003577
Saving checkpoint... 
Iteration: 340512969, states[0] = 27.917174, states[40]= 0.018156
Saving checkpoint... 
Iteration: 343469921, states[0] = -94.944291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346418882, states[0] = -94.927460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349355851, states[0] = -94.890151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352279995, states[0] = -94.796872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355243103, states[0] = -94.714856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358168849, states[0] = -91.413296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361110642, states[0] = -22.669778, states[40]= 0.001194
Saving checkpoint... 
Iteration: 364028427, states[0] = 25.211439, states[40]= 0.001583
Saving checkpoint... 
Iteration: 366931559, states[0] = -94.932406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369860587, states[0] = -94.893780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372801066, states[0] = -94.830669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375754267, states[0] = -94.743207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378698418, states[0] = -94.561181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381648685, states[0] = -62.033825, states[40]= 0.000013
Saving checkpoint... 
Iteration: 384575222, states[0] = 6.169463, states[40]= 0.004496
Saving checkpoint... 
Iteration: 387509928, states[0] = 27.974724, states[40]= 0.049144
Saving checkpoint... 
Iteration: 390444656, states[0] = -94.936870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393376126, states[0] = -94.904668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396280039, states[0] = -94.796778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399210113, states[0] = -94.607884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402150458, states[0] = -64.209061, states[40]= 0.000009
Saving checkpoint... 
Iteration: 405073585, states[0] = 7.037268, states[40]= 0.004432
Saving checkpoint... 
Iteration: 408004164, states[0] = 33.090873, states[40]= 0.328188
Saving checkpoint... 
Iteration: 410945909, states[0] = -94.937195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413872453, states[0] = -94.902148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416808863, states[0] = -94.841194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419734852, states[0] = -94.691235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422664139, states[0] = -85.383344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425597338, states[0] = -9.646062, states[40]= 0.002707
Saving checkpoint... 
Iteration: 428520061, states[0] = 27.228374, states[40]= 0.002744
Saving checkpoint... 
Iteration: 431474706, states[0] = -94.945117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434409168, states[0] = -94.922803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437342636, states[0] = -94.878440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440287429, states[0] = -94.809377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443220031, states[0] = -94.643658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446168439, states[0] = -91.054198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449103440, states[0] = -15.602334, states[40]= 0.001632
Saving checkpoint... 
Iteration: 452044454, states[0] = 19.683781, states[40]= 0.002362
Saving checkpoint... 
Iteration: 454980691, states[0] = -94.946408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457910026, states[0] = -94.923110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460867590, states[0] = -94.898589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463773831, states[0] = -94.784951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466709022, states[0] = -94.603457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469639980, states[0] = -52.080097, states[40]= 0.000065
Saving checkpoint... 
Iteration: 472572298, states[0] = 7.702283, states[40]= 0.004374
Saving checkpoint... 
Iteration: 475524792, states[0] = 26.206929, states[40]= 0.001667
Saving checkpoint... 
Iteration: 478470542, states[0] = -94.943919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481396892, states[0] = -94.916526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484329201, states[0] = -94.864979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487289660, states[0] = -94.812850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490212683, states[0] = -94.617163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493161151, states[0] = -80.177001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496120046, states[0] = -31.678823, states[40]= 0.000847
Saving checkpoint... 
Iteration: 499088527, states[0] = -2.166741, states[40]= 0.004216
Saving checkpoint... 
Iteration: 502028290, states[0] = 25.251742, states[40]= 0.001582
Saving checkpoint... 
Iteration: 504984587, states[0] = -94.947068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507907220, states[0] = -94.921599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510855271, states[0] = -94.889052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513780674, states[0] = -94.797455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516719225, states[0] = -94.640572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519649646, states[0] = -63.201980, states[40]= 0.000011
Saving checkpoint... 
Iteration: 522574097, states[0] = 6.768778, states[40]= 0.004454
Saving checkpoint... 
Iteration: 525518039, states[0] = 27.540698, states[40]= 0.004204
Saving checkpoint... 
Iteration: 528452356, states[0] = -94.938740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531404961, states[0] = -94.920421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534324831, states[0] = -94.860045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537280752, states[0] = -94.797502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540229619, states[0] = -94.674827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543175127, states[0] = -94.007840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546110896, states[0] = -22.914336, states[40]= 0.001190
Saving checkpoint... 
Iteration: 549035868, states[0] = 22.806886, states[40]= 0.001843
Saving checkpoint... 
Iteration: 551990243, states[0] = -94.948064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554925862, states[0] = -94.929493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557867602, states[0] = -94.898219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560811519, states[0] = -94.844075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563740962, states[0] = -94.708171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566702019, states[0] = -94.575382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569642362, states[0] = -54.727601, states[40]= 0.000043
Saving checkpoint... 
Iteration: 572570343, states[0] = 8.685480, states[40]= 0.004272
Saving checkpoint... 
Iteration: 575513787, states[0] = 27.895184, states[40]= 0.014012
Saving checkpoint... 
Iteration: 578454466, states[0] = -94.939172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581382866, states[0] = -94.908180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584318349, states[0] = -94.852404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587265779, states[0] = -94.768239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590202524, states[0] = -94.577343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593155564, states[0] = -71.084694, states[40]= 0.000003
Saving checkpoint... 
Iteration: 596084176, states[0] = 0.872865, states[40]= 0.004522
Saving checkpoint... 
Iteration: 599018890, states[0] = 27.419842, states[40]= 0.003461
Saving checkpoint... 
Iteration: 601960939, states[0] = -94.940922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604900911, states[0] = -94.918123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607841993, states[0] = -94.877180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610781583, states[0] = -94.798691, states[40]= 0.000000
Saving checkpoint... 
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Iteration: 828044018, states[0] = 19.848560, states[40]= 0.002333
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Iteration: 854517097, states[0] = 27.656136, states[40]= 0.005332
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Iteration: 880933360, states[0] = -94.931064, states[40]= 0.000000
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Iteration: 883871113, states[0] = -94.899399, states[40]= 0.000000
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Iteration: 895624925, states[0] = -36.400163, states[40]= 0.000538
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Iteration: 901528930, states[0] = 25.063188, states[40]= 0.001589
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Iteration: 904471003, states[0] = -94.942373, states[40]= 0.000000
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Iteration: 922101405, states[0] = -13.586122, states[40]= 0.001928
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Iteration: 925030593, states[0] = 24.554582, states[40]= 0.001626
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Iteration: 927971501, states[0] = -94.942404, states[40]= 0.000000
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Iteration: 930901497, states[0] = -94.917147, states[40]= 0.000000
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Iteration: 939727372, states[0] = -94.666133, states[40]= 0.000000
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Iteration: 942666561, states[0] = -88.984417, states[40]= 0.000000
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Iteration: 945615228, states[0] = -27.067100, states[40]= 0.001096
Saving checkpoint... 
Iteration: 948554240, states[0] = 15.854689, states[40]= 0.003104
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Iteration: 951498198, states[0] = -94.948050, states[40]= 0.000000
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Iteration: 954432751, states[0] = -94.930554, states[40]= 0.000000
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Iteration: 963263808, states[0] = -94.762564, states[40]= 0.000000
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Iteration: 966200577, states[0] = -94.567880, states[40]= 0.000000
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Iteration: 969149367, states[0] = -62.857270, states[40]= 0.000012
Saving checkpoint... 
Iteration: 972084725, states[0] = 0.510558, states[40]= 0.004499
Saving checkpoint... 
Iteration: 975013590, states[0] = 27.902121, states[40]= 0.014907
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Iteration: 977933151, states[0] = -94.930609, states[40]= 0.000000
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Iteration: 980873124, states[0] = -94.900386, states[40]= 0.000000
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Iteration: 992625181, states[0] = -36.650531, states[40]= 0.000523
Saving checkpoint... 
Iteration: 995553860, states[0] = 16.009051, states[40]= 0.003074
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Iteration: 1001410944, states[0] = -94.921411, states[40]= 0.000000
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Iteration: 1007293967, states[0] = -94.817624, states[40]= 0.000000
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Iteration: 1010242512, states[0] = -94.710670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013181802, states[0] = -94.434470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016112191, states[0] = -24.159239, states[40]= 0.001169
Saving checkpoint... 
Iteration: 1019053934, states[0] = 15.979073, states[40]= 0.003080
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Iteration: 1021999079, states[0] = -94.947938, states[40]= 0.000000
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Iteration: 1024941854, states[0] = -94.933471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027897907, states[0] = -94.914926, states[40]= 0.000000
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Iteration: 1030845979, states[0] = -94.879144, states[40]= 0.000000
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Iteration: 1033785681, states[0] = -94.804121, states[40]= 0.000000
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Iteration: 1036710382, states[0] = -94.606381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039658411, states[0] = -75.491125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1042560053, states[0] = 13.422250, states[40]= 0.003566
Saving checkpoint... 
Iteration: 1045490690, states[0] = -94.946231, states[40]= 0.000000
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Iteration: 1048437046, states[0] = -94.931731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051384571, states[0] = -94.907373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054317780, states[0] = -94.849885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057257132, states[0] = -94.747275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060203170, states[0] = -94.578095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063139577, states[0] = -51.633044, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1066072112, states[0] = 7.798085, states[40]= 0.004365
Saving checkpoint... 
Iteration: 1069010136, states[0] = 27.965839, states[40]= 0.045859
Saving checkpoint... 
Iteration: 1071974962, states[0] = -94.942681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074914685, states[0] = -94.922805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077846676, states[0] = -94.879578, states[40]= 0.000000
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Iteration: 1080793071, states[0] = -94.815945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083722314, states[0] = -94.648923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086653575, states[0] = -68.268112, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1089583784, states[0] = 1.129819, states[40]= 0.004537
Saving checkpoint... 
Iteration: 1092541455, states[0] = 20.803852, states[40]= 0.002164
Saving checkpoint... 
Iteration: 1095476169, states[0] = -94.942875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098397420, states[0] = -94.914396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101335127, states[0] = -94.868653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104273052, states[0] = -94.780928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107211231, states[0] = -94.609303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110158139, states[0] = -75.047744, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113077959, states[0] = 4.658948, states[40]= 0.004570
Saving checkpoint... 
Iteration: 1116009741, states[0] = 27.986151, states[40]= 0.052296
Saving checkpoint... 
Iteration: 1118962416, states[0] = -94.939310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121900049, states[0] = -94.915667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124828744, states[0] = -94.861988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127765840, states[0] = -94.766243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130702809, states[0] = -94.576357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133662660, states[0] = -82.834116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136575537, states[0] = 6.000712, states[40]= 0.004507
Saving checkpoint... 
Iteration: 1139512863, states[0] = 27.920151, states[40]= 0.018782
Saving checkpoint... 
Iteration: 1142456759, states[0] = -94.937640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145383385, states[0] = -94.906292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148312024, states[0] = -94.842418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151229495, states[0] = -94.672027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154153551, states[0] = -68.234794, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1157115148, states[0] = -26.989961, states[40]= 0.001099
Saving checkpoint... 
Iteration: 1160040242, states[0] = 21.248869, states[40]= 0.002088
Saving checkpoint... 
Iteration: 1162967402, states[0] = -94.940455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165897091, states[0] = -94.913960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168822983, states[0] = -94.855491, states[40]= 0.000000
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Iteration: 1171762854, states[0] = -94.759679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174697292, states[0] = -94.553223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177663690, states[0] = -84.618058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180573848, states[0] = 6.900778, states[40]= 0.004444
Saving checkpoint... 
Iteration: 1183512183, states[0] = 27.930162, states[40]= 0.023390
Saving checkpoint... 
Iteration: 1186434831, states[0] = -94.930405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189349914, states[0] = -94.881953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192242803, states[0] = -94.710744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195203022, states[0] = -94.576962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198147795, states[0] = -60.964220, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1201062364, states[0] = 12.413313, states[40]= 0.003743
Saving checkpoint... 
Iteration: 1204020453, states[0] = 27.159206, states[40]= 0.002564
Saving checkpoint... 
Iteration: 1206959707, states[0] = -94.938222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209886704, states[0] = -94.908017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212814846, states[0] = -94.845700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215719464, states[0] = -94.638641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218663730, states[0] = -84.685372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221594422, states[0] = -6.971122, states[40]= 0.003307
Saving checkpoint... 
Iteration: 1224507439, states[0] = 28.452695, states[40]= 0.112823
Saving checkpoint... 
Iteration: 1227454219, states[0] = -94.936569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230390177, states[0] = -94.909934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233317783, states[0] = -94.849188, states[40]= 0.000000
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Iteration: 1236267356, states[0] = -94.768982, states[40]= 0.000000
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Iteration: 1239206002, states[0] = -94.588670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242143318, states[0] = -55.798672, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1245071023, states[0] = 8.348105, states[40]= 0.004310
Saving checkpoint... 
Iteration: 1247984237, states[0] = -94.944097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250923988, states[0] = -94.926033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253865077, states[0] = -94.893681, states[40]= 0.000000
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Iteration: 1256772857, states[0] = -94.779950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259688177, states[0] = -94.507493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262587510, states[0] = -1.419473, states[40]= 0.004314
Saving checkpoint... 
Iteration: 1265508528, states[0] = 28.128643, states[40]= 0.078393
Saving checkpoint... 
Iteration: 1268449311, states[0] = -94.934925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271365574, states[0] = -94.893974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274282270, states[0] = -94.797298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277189430, states[0] = -94.515112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280122464, states[0] = -34.005587, states[40]= 0.000690
Saving checkpoint... 
Iteration: 1283049137, states[0] = 17.887112, states[40]= 0.002704
Saving checkpoint... 
Iteration: 1285992681, states[0] = -94.945690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288927969, states[0] = -94.927451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291864950, states[0] = -94.893439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294797543, states[0] = -94.821917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297716400, states[0] = -94.627511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300644776, states[0] = -57.453191, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1303578482, states[0] = 4.360919, states[40]= 0.004579
Saving checkpoint... 
Iteration: 1306518980, states[0] = 27.406990, states[40]= 0.003395
Saving checkpoint... 
Iteration: 1309454677, states[0] = -94.936384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312378202, states[0] = -94.902418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315319152, states[0] = -94.850493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318228556, states[0] = -94.668410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321169357, states[0] = -91.804256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324115571, states[0] = -27.393627, states[40]= 0.001084
Saving checkpoint... 
Iteration: 1327038978, states[0] = 21.707356, states[40]= 0.002013
Saving checkpoint... 
Iteration: 1329976367, states[0] = -94.942007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332892579, states[0] = -94.910875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335839082, states[0] = -94.871594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338774834, states[0] = -94.783437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341721693, states[0] = -94.645801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344642450, states[0] = -54.822163, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1347589874, states[0] = -3.188712, states[40]= 0.004059
Saving checkpoint... 
Iteration: 1350537644, states[0] = 22.184500, states[40]= 0.001937
Saving checkpoint... 
Iteration: 1353468264, states[0] = -94.939934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356410355, states[0] = -94.919755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359340394, states[0] = -94.872747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362276726, states[0] = -94.786914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365206505, states[0] = -94.590146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368145682, states[0] = -58.492747, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1371076121, states[0] = 5.683318, states[40]= 0.004525
Saving checkpoint... 
Iteration: 1374031236, states[0] = 24.352268, states[40]= 0.001646
Saving checkpoint... 
Iteration: 1376964446, states[0] = -94.938849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379910898, states[0] = -94.919913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382855221, states[0] = -94.885604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385798553, states[0] = -94.823054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388712675, states[0] = -94.613579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391641159, states[0] = -53.381156, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1394585218, states[0] = 0.180727, states[40]= 0.004474
Saving checkpoint... 
Iteration: 1397541545, states[0] = 20.771016, states[40]= 0.002170
Saving checkpoint... 
Iteration: 1400458223, states[0] = -94.937051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403368945, states[0] = -94.895865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406320264, states[0] = -94.851439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409276987, states[0] = -94.787216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412228490, states[0] = -94.667830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415170411, states[0] = -92.495006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418076345, states[0] = 5.560570, states[40]= 0.004532
Saving checkpoint... 
Iteration: 1420996527, states[0] = -94.945907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423951002, states[0] = -94.934838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426864805, states[0] = -94.892806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429803553, states[0] = -94.830038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432746350, states[0] = -94.719245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435682414, states[0] = -94.444899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438621539, states[0] = -33.111918, states[40]= 0.000751
Saving checkpoint... 
Iteration: 1441574947, states[0] = 6.318737, states[40]= 0.004486
Saving checkpoint... 
Iteration: 1444533447, states[0] = 23.631806, states[40]= 0.001730
Saving checkpoint... 
Iteration: 1447476676, states[0] = -94.941621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450390443, states[0] = -94.909226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453337919, states[0] = -94.870017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456273107, states[0] = -94.779653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459207209, states[0] = -94.592524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462126082, states[0] = -37.534403, states[40]= 0.000473
Saving checkpoint... 
Iteration: 1465074613, states[0] = 6.497011, states[40]= 0.004474
Saving checkpoint... 
Iteration: 1468011513, states[0] = 27.937351, states[40]= 0.029105
Saving checkpoint... 
Iteration: 1470943003, states[0] = -94.932114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473890260, states[0] = -94.909031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476818389, states[0] = -94.848957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479761770, states[0] = -94.756095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482674802, states[0] = -93.952138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485611116, states[0] = -23.123460, states[40]= 0.001186
Saving checkpoint... 
Iteration: 1488549642, states[0] = 17.689879, states[40]= 0.002743
Saving checkpoint... 
Iteration: 1491471479, states[0] = -94.940202, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387_1_r1628593356_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_387_1_r1628593356_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 97.723621
     * GNaL_b in INaL: 0.006805
     * Gto_b in Ito: 0.082741
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032890
     * GKs_b in IKs: 0.002016
     * GK1_b in IK1: 0.173032
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 71.864706
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041273
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1491471479
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.940202 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1494396676, states[0] = -94.912458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497317813, states[0] = -94.848191, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.822119
 - CaMKt in component CaMK (millimolar): 0.012542
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.737448
 - nass in component intracellular_ions (millimolar): 6.737544
 - ki in component intracellular_ions (millimolar): 145.146727
 - kss in component intracellular_ions (millimolar): 145.146705
 - cansr in component intracellular_ions (millimolar): 1.653610
 - cajsr in component intracellular_ions (millimolar): 1.611739
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003648
 - hf in component INa (dimensionless): 0.878610
 - hs in component INa (dimensionless): 0.878603
 - j in component INa (dimensionless): 0.878556
 - hsp in component INa (dimensionless): 0.723199
 - jp in component INa (dimensionless): 0.878524
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705754
 - hLp in component INaL (dimensionless): 0.443980
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612645
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683773
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916002
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999834
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002985
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.363480
 - xs1 in component IKs (dimensionless): 0.267387
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997358
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:48:11 (296012): called boinc_finish(0)

</stderr_txt>
]]>


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