𝕏

Task 55137272

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_686_0
Workunit 26182278
Created 28 Jun 2024, 5:30:52 UTC
Sent 28 Jun 2024, 17:17:02 UTC
Report deadline 1 Jul 2024, 17:17:02 UTC
Received 29 Jun 2024, 0:44:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 47 min 40 sec
CPU time 1 hours 40 min 32 sec
Validate state Valid
Credit 43.60
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.81 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_686.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_686_0_r976386044_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_686_0_r976386044_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.926893
     * GNaL_b in INaL: 0.005201
     * Gto_b in Ito: 0.080317
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032523
     * GKs_b in IKs: 0.001880
     * GK1_b in IK1: 0.150712
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.970273
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023346
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11496708, states[0] = -94.070238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22193051, states[0] = -94.077729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32625559, states[0] = -94.056250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43904174, states[0] = -94.072141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54660653, states[0] = -94.094924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66713222, states[0] = -94.111165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77572748, states[0] = -94.089911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87249520, states[0] = -51.041623, states[40]= 0.000414
Saving checkpoint... 
Iteration: 97717551, states[0] = -94.108450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107212709, states[0] = -94.104533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116822318, states[0] = -94.103336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127768203, states[0] = -94.115048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137847913, states[0] = -94.106986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148151062, states[0] = -94.134075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158852651, states[0] = -94.109164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169395309, states[0] = -94.127954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180527219, states[0] = -94.085344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191496552, states[0] = -94.112373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201983096, states[0] = -94.142415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213063472, states[0] = 28.657308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222880152, states[0] = -94.144905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232890691, states[0] = -94.119089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242599374, states[0] = -94.112584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251961055, states[0] = -94.111385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261396751, states[0] = -93.925363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270798031, states[0] = -94.144737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281584194, states[0] = -94.112670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292555862, states[0] = -94.125468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303438144, states[0] = -93.999682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314741718, states[0] = -94.111868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326513997, states[0] = -94.112862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337738901, states[0] = -94.121438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349878245, states[0] = -94.119026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360837579, states[0] = -94.144832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372812997, states[0] = -94.144541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384035669, states[0] = 34.216592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395967551, states[0] = -94.110763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407617401, states[0] = -94.111843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419742667, states[0] = -94.111247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431217898, states[0] = -94.114417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442933807, states[0] = -94.117631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454298925, states[0] = -94.131556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465730810, states[0] = -94.140608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477425344, states[0] = -93.978836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489194202, states[0] = -23.760116, states[40]= 0.004068
Saving checkpoint... 
Iteration: 500837589, states[0] = -94.110413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512216533, states[0] = -94.113906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523359235, states[0] = -94.129279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 535221128, states[0] = -94.133539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547165372, states[0] = -94.135336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559419813, states[0] = -94.127319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571394068, states[0] = -94.127961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582543078, states[0] = -94.094014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594413806, states[0] = -93.957919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606092093, states[0] = 18.809195, states[40]= 0.000003
Saving checkpoint... 
Iteration: 618101181, states[0] = 15.466596, states[40]= 0.000008
Saving checkpoint... 
Iteration: 629540342, states[0] = -94.110796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641808941, states[0] = -94.109583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653267299, states[0] = -94.112534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664751432, states[0] = -94.119121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676842126, states[0] = -94.117494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689534407, states[0] = -94.110438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701882075, states[0] = -94.108982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713078709, states[0] = -94.114028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726080569, states[0] = 22.961912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738068192, states[0] = 27.166522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749350318, states[0] = -94.111240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759150934, states[0] = -3.711728, states[40]= 0.000342
Saving checkpoint... 
Iteration: 771165291, states[0] = -11.337779, states[40]= 0.000488
Saving checkpoint... 
Iteration: 779761814, states[0] = -94.108841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793242887, states[0] = -94.131147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804098585, states[0] = 16.425144, states[40]= 0.000006
Saving checkpoint... 
Iteration: 815233582, states[0] = -94.111779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826944408, states[0] = -94.114988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838533862, states[0] = -94.122563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849081534, states[0] = 22.620721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860020259, states[0] = -94.113772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871366380, states[0] = -94.126809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883428152, states[0] = -94.124985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894271985, states[0] = -78.632904, states[40]= 0.000006
Saving checkpoint... 
Iteration: 904937843, states[0] = -94.114572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916941503, states[0] = -94.114443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928132617, states[0] = -94.133981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939752465, states[0] = -94.138906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951338615, states[0] = -93.746766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963604284, states[0] = -94.116359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976153186, states[0] = -94.132966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988833102, states[0] = -94.115611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001085395, states[0] = -94.112079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013846346, states[0] = -94.107049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025223803, states[0] = -94.110502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038149618, states[0] = -3.099487, states[40]= 0.000323
Saving checkpoint... 
Iteration: 1050423503, states[0] = -93.972007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062636005, states[0] = -94.123835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074723875, states[0] = -94.136122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087215566, states[0] = -94.130139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099849273, states[0] = -94.114629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111919840, states[0] = -94.113482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124481781, states[0] = -94.107910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136600393, states[0] = -94.107188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148600899, states[0] = -94.107107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161318451, states[0] = -93.657046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173820813, states[0] = -94.139459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186389382, states[0] = -94.124098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198742433, states[0] = -94.115814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210837059, states[0] = -94.114103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222670429, states[0] = -94.117047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1235299761, states[0] = -94.108475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248572249, states[0] = -94.103312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260542824, states[0] = -94.089462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272788333, states[0] = -94.138195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286325550, states[0] = -94.107937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298402991, states[0] = -94.107288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310945603, states[0] = -94.104864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324287152, states[0] = -94.126276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336711145, states[0] = -94.115504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348827063, states[0] = -94.113368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360639325, states[0] = -94.116792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372324783, states[0] = -94.124797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385162312, states[0] = -94.108755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1397656412, states[0] = -94.105231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409987839, states[0] = -94.104132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422289958, states[0] = -93.337156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433466481, states[0] = -94.105993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445494076, states[0] = -94.105748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457368486, states[0] = -94.106498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469528795, states[0] = -94.105393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481753530, states[0] = -94.104301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494012445, states[0] = 30.884527, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.979502
 - CaMKt in component CaMK (millimolar): 0.001349
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.723249
 - nass in component intracellular_ions (millimolar): 7.723396
 - ki in component intracellular_ions (millimolar): 144.116744
 - kss in component intracellular_ions (millimolar): 144.116731
 - cansr in component intracellular_ions (millimolar): 1.766319
 - cajsr in component intracellular_ions (millimolar): 1.767521
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003972
 - hf in component INa (dimensionless): 0.863051
 - hs in component INa (dimensionless): 0.863051
 - j in component INa (dimensionless): 0.863052
 - hsp in component INa (dimensionless): 0.694690
 - jp in component INa (dimensionless): 0.863052
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704168
 - hLp in component INaL (dimensionless): 0.509807
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.999134
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999677
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999288
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004263
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000659
 - xs1 in component IKs (dimensionless): 0.019462
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997569
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:31:25 (78493): called boinc_finish(0)

</stderr_txt>
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