𝕏

Task 55134360

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_EPI_4000-conf_683_0
Workunit 26180823
Created 28 Jun 2024, 5:29:32 UTC
Sent 28 Jun 2024, 16:56:09 UTC
Report deadline 1 Jul 2024, 16:56:09 UTC
Received 29 Jun 2024, 9:30:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 48 min 17 sec
CPU time 2 hours 19 min 49 sec
Validate state Valid
Credit 45.86
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.62 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_EPI_4000-conf_683.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_EPI_4000-conf_683_0_r831862542_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_EPI_4000-conf_683_0_r831862542_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 117.070056
     * GNaL_b in INaL: 0.007560
     * Gto_b in Ito: 0.081219
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033686
     * GKs_b in IKs: 0.001786
     * GK1_b in IK1: 0.152737
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 73.690813
     * GKb_b in IKb: 0.003732
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022923
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8226458, states[0] = -93.757187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16785075, states[0] = -94.098453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25482372, states[0] = -94.040553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33909085, states[0] = -94.015015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42131378, states[0] = -23.994285, states[40]= 0.000215
Saving checkpoint... 
Iteration: 50358456, states[0] = -93.927094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58730541, states[0] = -94.049655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67367823, states[0] = -94.023357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75741162, states[0] = -94.015842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84073985, states[0] = 17.326826, states[40]= 0.000004
Saving checkpoint... 
Iteration: 92364257, states[0] = -93.947391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101098266, states[0] = -94.044532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109772812, states[0] = -94.024236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118091533, states[0] = 8.459526, states[40]= 0.000043
Saving checkpoint... 
Iteration: 126126232, states[0] = -20.852802, states[40]= 0.000244
Saving checkpoint... 
Iteration: 134398105, states[0] = -93.994085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142608539, states[0] = -94.068210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151386342, states[0] = -94.039228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159423558, states[0] = -94.038378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167630426, states[0] = -94.032756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175967629, states[0] = -94.025937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184706018, states[0] = -94.070627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193047394, states[0] = -94.054440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201309550, states[0] = -94.043118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209251386, states[0] = -94.045372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217376919, states[0] = -94.040734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225449813, states[0] = -94.038327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233685056, states[0] = -94.031880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242467281, states[0] = -94.041920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251073193, states[0] = -94.053052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259625704, states[0] = -94.033138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268295863, states[0] = -93.809280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276374574, states[0] = -93.970276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284477455, states[0] = -94.045660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292961880, states[0] = -94.058310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301081129, states[0] = -94.052175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309991953, states[0] = -94.025057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318140163, states[0] = -36.503934, states[40]= 0.000289
Saving checkpoint... 
Iteration: 326189448, states[0] = -92.652616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334925928, states[0] = -94.059749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342885290, states[0] = -94.061824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350948744, states[0] = -94.058348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359560019, states[0] = -94.033776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367475580, states[0] = -94.036116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376188856, states[0] = -92.545770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384822749, states[0] = -94.064571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392824636, states[0] = -94.064383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401114804, states[0] = -94.049422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409501469, states[0] = -94.034848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418173970, states[0] = -77.782214, states[40]= 0.000002
Saving checkpoint... 
Iteration: 426193994, states[0] = -93.082100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434174959, states[0] = -79.305233, states[40]= 0.000002
Saving checkpoint... 
Iteration: 442378528, states[0] = -93.973188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450571800, states[0] = -94.064650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458853477, states[0] = -94.062133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467782156, states[0] = -94.027144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476556138, states[0] = -94.062461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484641078, states[0] = -94.068212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492144318, states[0] = -41.336422, states[40]= 0.000201
Saving checkpoint... 
Iteration: 500600707, states[0] = -94.066451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508460268, states[0] = -94.035786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516541920, states[0] = -94.059848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525396172, states[0] = -94.036771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533380035, states[0] = -94.037220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541025670, states[0] = -94.052100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549255294, states[0] = -94.041616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556746909, states[0] = -94.065881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565116615, states[0] = -94.047391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574066959, states[0] = 19.908002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 582251962, states[0] = -93.623047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589295959, states[0] = -94.039569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596361352, states[0] = -93.948692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603306546, states[0] = -94.039005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610165876, states[0] = -66.723662, states[40]= 0.000009
Saving checkpoint... 
Iteration: 617201150, states[0] = -94.043024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624332446, states[0] = -93.898405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631473202, states[0] = -94.033054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639187364, states[0] = -94.043350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646762808, states[0] = -94.064204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654220706, states[0] = -93.423288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662008515, states[0] = 19.867369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669221959, states[0] = -94.041539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677585582, states[0] = -94.029312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686631574, states[0] = -94.065600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694878316, states[0] = -94.058030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702700928, states[0] = -94.065478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711329062, states[0] = -94.036896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719228065, states[0] = -94.040695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726191124, states[0] = -92.868099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733933173, states[0] = -94.021049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742622883, states[0] = -94.064662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749904714, states[0] = -94.021374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757807412, states[0] = -94.023169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764988395, states[0] = -94.051359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773438245, states[0] = -94.032453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781802673, states[0] = -94.022979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789874426, states[0] = -94.021462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796587917, states[0] = -94.062038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805165473, states[0] = -94.042330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813541717, states[0] = -94.028890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821291119, states[0] = -94.036994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829261026, states[0] = -94.038062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837097156, states[0] = -94.045074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846010368, states[0] = 21.210566, states[40]= -0.000000
Saving checkpoint... 
Iteration: 854368659, states[0] = -93.955805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863145058, states[0] = -94.042550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871676569, states[0] = -94.024708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880091876, states[0] = 8.127152, states[40]= 0.000045
Saving checkpoint... 
Iteration: 887919459, states[0] = -94.019460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896341631, states[0] = -93.912885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904235704, states[0] = -93.523680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912731459, states[0] = -94.062189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921436167, states[0] = -94.030759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929580976, states[0] = -94.026436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937801654, states[0] = -94.021144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945887997, states[0] = -94.019350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954115589, states[0] = -9.643900, states[40]= 0.000239
Saving checkpoint... 
Iteration: 962826157, states[0] = -94.057551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971780272, states[0] = -94.021188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980464722, states[0] = -94.032212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989015631, states[0] = -94.047294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997051909, states[0] = -94.045373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005120048, states[0] = -94.042009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013435298, states[0] = -94.029695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021995896, states[0] = -94.016543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030598059, states[0] = -94.060004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039028351, states[0] = -94.046054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047062198, states[0] = -94.044272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055505891, states[0] = -94.027040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063322484, states[0] = -94.032953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071959634, states[0] = -94.016563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080455945, states[0] = -94.026927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088603133, states[0] = -94.059632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096851372, states[0] = -94.054677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105587441, states[0] = -94.024173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114156622, states[0] = -55.900252, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1122595850, states[0] = -94.058765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131156397, states[0] = -94.038861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139751086, states[0] = -94.019818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148199024, states[0] = -93.218861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156235182, states[0] = -93.517235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164782665, states[0] = -94.057221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173185885, states[0] = -94.037072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181395316, states[0] = -94.029002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189798531, states[0] = -94.018211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198170536, states[0] = -72.743683, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1206150223, states[0] = -48.362056, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1214740000, states[0] = -94.058328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223147598, states[0] = -94.038162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230865354, states[0] = -94.052357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239013089, states[0] = -94.044457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247306125, states[0] = -94.031370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255953765, states[0] = -94.014475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264096317, states[0] = 5.511499, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1272824325, states[0] = -94.053968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280642625, states[0] = -94.058810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289322345, states[0] = -94.030273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297509585, states[0] = -94.024055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306224569, states[0] = -93.443280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314398001, states[0] = -93.983647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323062823, states[0] = -94.040965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331427717, states[0] = -94.026158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340016211, states[0] = 23.782318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348254309, states[0] = -93.626092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356521818, states[0] = -94.046035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364523250, states[0] = -94.046250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372462788, states[0] = -94.026692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381084941, states[0] = -94.039199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389799711, states[0] = -94.015807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397777207, states[0] = -94.016184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406073594, states[0] = 17.235378, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1414496610, states[0] = -94.038823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422357694, states[0] = -93.933401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431097358, states[0] = -94.038012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438946352, states[0] = -94.045574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446973064, states[0] = -94.044065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455232031, states[0] = -94.031786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463045768, states[0] = -94.040143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471504108, states[0] = -94.022143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479710667, states[0] = -94.016678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488020565, states[0] = 25.014112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496180673, states[0] = -87.556171, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.886753
 - CaMKt in component CaMK (millimolar): 0.002340
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.134399
 - nass in component intracellular_ions (millimolar): 7.134535
 - ki in component intracellular_ions (millimolar): 144.542217
 - kss in component intracellular_ions (millimolar): 144.542203
 - cansr in component intracellular_ions (millimolar): 2.422263
 - cajsr in component intracellular_ions (millimolar): 2.422695
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004009
 - hf in component INa (dimensionless): 0.861240
 - hs in component INa (dimensionless): 0.861241
 - j in component INa (dimensionless): 0.861245
 - hsp in component INa (dimensionless): 0.691452
 - jp in component INa (dimensionless): 0.861247
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701626
 - hLp in component INaL (dimensionless): 0.506382
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.999844
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.999844
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996785
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005354
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006996
 - xs1 in component IKs (dimensionless): 0.039218
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997591
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:30:07 (3696): called boinc_finish(0)

</stderr_txt>
]]>


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