𝕏

Task 55133597

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_282_1
Workunit 26180441
Created 28 Jun 2024, 5:29:11 UTC
Sent 28 Jun 2024, 16:54:07 UTC
Report deadline 1 Jul 2024, 16:54:07 UTC
Received 29 Jun 2024, 10:47:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217204
Run time 8 hours 57 min 23 sec
CPU time 8 hours 57 min 20 sec
Validate state Valid
Credit 44.04
Device peak FLOPS 1.48 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 10.95 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_282.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_282_1_r293762092_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_6000-conf_282_1_r293762092_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.602244
     * GNaL_b in INaL: 0.004706
     * Gto_b in Ito: 0.074405
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031731
     * GKs_b in IKs: 0.001761
     * GK1_b in IK1: 0.169157
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 73.225588
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031993
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8468840, states[0] = -94.250623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16938142, states[0] = -94.229253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25319149, states[0] = -94.241267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33725632, states[0] = -94.249238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42110975, states[0] = 13.574546, states[40]= 0.000012
Saving checkpoint... 
Iteration: 50504559, states[0] = -94.233447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58908238, states[0] = -94.243553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67299206, states[0] = -94.260014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75791923, states[0] = -94.273515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84185602, states[0] = -18.810204, states[40]= 0.001723
Saving checkpoint... 
Iteration: 92588471, states[0] = -94.250178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101006448, states[0] = -94.256892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109404276, states[0] = -94.269296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117798273, states[0] = -94.283747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126244848, states[0] = -45.629894, states[40]= 0.000888
Saving checkpoint... 
Iteration: 134624882, states[0] = -94.257028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143041621, states[0] = -94.262126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151421906, states[0] = -94.273335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159802717, states[0] = -94.287428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168202959, states[0] = -24.822269, states[40]= 0.005017
Saving checkpoint... 
Iteration: 176641847, states[0] = -94.259311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185027543, states[0] = -94.264123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193414503, states[0] = -94.274930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201810901, states[0] = -94.288667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210216208, states[0] = -29.808246, states[40]= 0.004714
Saving checkpoint... 
Iteration: 218602049, states[0] = -94.260145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227060224, states[0] = -94.264231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235470166, states[0] = -94.273924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243898164, states[0] = -94.288912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252304821, states[0] = -93.782412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260690945, states[0] = -94.259813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269077020, states[0] = -94.264047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277463584, states[0] = -94.274021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285850637, states[0] = -94.289103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294300323, states[0] = -93.753032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302684283, states[0] = -94.259694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311068023, states[0] = -94.263975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319450530, states[0] = -94.274143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327835229, states[0] = -94.288853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336218111, states[0] = -30.784047, states[40]= 0.004423
Saving checkpoint... 
Iteration: 344604029, states[0] = -94.259831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352988118, states[0] = -94.264657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361414631, states[0] = -94.274781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 369836971, states[0] = -94.288630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378215225, states[0] = -29.478662, states[40]= 0.004778
Saving checkpoint... 
Iteration: 386598331, states[0] = -94.259619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394981151, states[0] = -94.264499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403365732, states[0] = -94.275772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411742522, states[0] = -94.285680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420202869, states[0] = -24.977044, states[40]= 0.004978
Saving checkpoint... 
Iteration: 428586918, states[0] = -94.259427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436967811, states[0] = -94.264413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445350712, states[0] = -94.275916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453730491, states[0] = -94.284663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462177286, states[0] = -16.662397, states[40]= 0.000877
Saving checkpoint... 
Iteration: 470559815, states[0] = -94.259311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478942298, states[0] = -94.264482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487322829, states[0] = -94.276408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495789287, states[0] = -94.287143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504309147, states[0] = -93.803381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512706311, states[0] = -94.258403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521083058, states[0] = -94.262602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529461178, states[0] = -94.272671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537896551, states[0] = -94.287411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546334223, states[0] = -93.910461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554737257, states[0] = -94.258033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563123082, states[0] = -94.261942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571553616, states[0] = -94.270371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579956028, states[0] = -94.286154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588326869, states[0] = -93.881228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596806543, states[0] = -94.257541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605241733, states[0] = -94.260609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613646446, states[0] = -94.268279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622104644, states[0] = -94.281915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630492550, states[0] = -94.210072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638938414, states[0] = -94.256916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647353034, states[0] = -94.259501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655737535, states[0] = -94.266418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664130167, states[0] = -94.280905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672516974, states[0] = -94.226941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680930342, states[0] = -94.256685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689332450, states[0] = -94.259397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697770481, states[0] = -94.265629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706180159, states[0] = -94.279164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714567532, states[0] = -94.251771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722970436, states[0] = -94.256338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731420652, states[0] = -94.258543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739804942, states[0] = -94.264839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748195248, states[0] = -94.278466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756580587, states[0] = -94.256276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764968870, states[0] = -94.256090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773354820, states[0] = -94.258734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781743156, states[0] = -94.265570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790132459, states[0] = -94.280083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798571902, states[0] = -94.252926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806979266, states[0] = -94.255815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815401431, states[0] = -94.258165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823872529, states[0] = -94.263349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832259147, states[0] = -94.276111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840647992, states[0] = -94.272718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849067884, states[0] = 27.386191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857459266, states[0] = -94.257550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865843958, states[0] = -94.263504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874236681, states[0] = -94.276504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 882623179, states[0] = -94.267485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891014621, states[0] = 32.586573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899404889, states[0] = -94.257639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907792417, states[0] = -94.264027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916181432, states[0] = -94.277871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924570820, states[0] = -94.251767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932958055, states[0] = -94.255108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941347029, states[0] = -94.257783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949731035, states[0] = -94.264767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958118151, states[0] = -94.279506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966537344, states[0] = -94.236733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974925522, states[0] = -94.254936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983316921, states[0] = -94.257751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991753517, states[0] = -94.264144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000197413, states[0] = -94.276896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008610057, states[0] = -94.263556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017006456, states[0] = 26.326800, states[40]= 0.003179
Saving checkpoint... 
Iteration: 1025392957, states[0] = -94.256963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033785156, states[0] = -94.263386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042198275, states[0] = -94.276620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050588392, states[0] = -94.257090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058980647, states[0] = -94.254302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067372224, states[0] = -94.256852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075799628, states[0] = -94.262910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084193580, states[0] = -94.276507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092590695, states[0] = -94.257562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100986221, states[0] = -94.254038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109378463, states[0] = -94.256558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117867698, states[0] = -94.261657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126261122, states[0] = -94.274297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134657472, states[0] = -94.272556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143053060, states[0] = 31.710580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151449520, states[0] = -94.255849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159854382, states[0] = -94.261594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168247252, states[0] = -94.274442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176640572, states[0] = -94.269347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185037006, states[0] = 34.540770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193430161, states[0] = -94.255717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201827615, states[0] = -94.261733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210300329, states[0] = -94.272699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218700465, states[0] = -94.277571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227097524, states[0] = 16.949698, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1235491208, states[0] = -94.255100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243885365, states[0] = -94.260657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252280884, states[0] = -94.272987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260698225, states[0] = -94.277093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269092856, states[0] = 18.647329, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1277485513, states[0] = -94.254881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285882257, states[0] = -94.260449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294276738, states[0] = -94.272852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302671655, states[0] = -94.273663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311080940, states[0] = 22.928460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319545337, states[0] = -94.254302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327941320, states[0] = -94.259414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336340544, states[0] = -94.270858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344842630, states[0] = -94.282841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353245659, states[0] = -47.912483, states[40]= 0.000637
Saving checkpoint... 
Iteration: 1361640591, states[0] = -94.253592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370112254, states[0] = -94.257220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378534376, states[0] = -94.265952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1386945108, states[0] = -94.281559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395443225, states[0] = -94.155953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403861630, states[0] = -94.252539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1412260526, states[0] = -94.255623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420658148, states[0] = -94.263234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429054809, states[0] = -94.278548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437466163, states[0] = -94.181655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445890495, states[0] = -94.252206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454286859, states[0] = -94.255161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462734859, states[0] = -94.261634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471159733, states[0] = -94.275199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479574348, states[0] = -94.249746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487974639, states[0] = -94.251746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496373415, states[0] = -94.254275, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.127598
 - CaMKt in component CaMK (millimolar): 0.001332
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.630010
 - nass in component intracellular_ions (millimolar): 7.630158
 - ki in component intracellular_ions (millimolar): 144.216894
 - kss in component intracellular_ions (millimolar): 144.216881
 - cansr in component intracellular_ions (millimolar): 1.750025
 - cajsr in component intracellular_ions (millimolar): 1.751044
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.003913
 - hf in component INa (dimensionless): 0.865902
 - hs in component INa (dimensionless): 0.865902
 - j in component INa (dimensionless): 0.865903
 - hsp in component INa (dimensionless): 0.699827
 - jp in component INa (dimensionless): 0.865903
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708272
 - hLp in component INaL (dimensionless): 0.514747
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999140
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999683
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999271
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004134
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000640
 - xs1 in component IKs (dimensionless): 0.019711
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:46:47 (15182): called boinc_finish(0)

</stderr_txt>
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