𝕏

Task 55132324

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_5000-conf_181_0
Workunit 26179805
Created 28 Jun 2024, 5:28:33 UTC
Sent 28 Jun 2024, 16:43:07 UTC
Report deadline 1 Jul 2024, 16:43:07 UTC
Received 29 Jun 2024, 3:32:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 17 min
CPU time 2 hours 12 min 9 sec
Validate state Valid
Credit 42.38
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.20 MB
Peak swap size 2.35 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_5000-conf_181.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_5000-conf_181_0_r319795537_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_5000-conf_181_0_r319795537_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.261970
     * GNaL_b in INaL: 0.004424
     * Gto_b in Ito: 0.075570
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032986
     * GKs_b in IKs: 0.001785
     * GK1_b in IK1: 0.165318
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.413721
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038266
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11175728, states[0] = -94.648605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22356696, states[0] = -94.572131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33504941, states[0] = -94.547001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44721370, states[0] = -94.509747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55867611, states[0] = -94.511386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66804583, states[0] = -94.488196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77976027, states[0] = -94.459910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89122038, states[0] = -94.478338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100291888, states[0] = -94.277859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111508345, states[0] = -94.473543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122698139, states[0] = -93.726674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133999258, states[0] = -94.470204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145006103, states[0] = 29.103572, states[40]= 0.168549
Saving checkpoint... 
Iteration: 156191717, states[0] = -94.473215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167369418, states[0] = -94.460321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178567349, states[0] = -94.474458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189775777, states[0] = -94.459940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200966244, states[0] = -94.475663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212146691, states[0] = -94.460190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223059983, states[0] = -94.462630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234253407, states[0] = -94.463006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245434698, states[0] = -94.423265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256652704, states[0] = -94.463888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267869062, states[0] = -94.376219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279110480, states[0] = -94.464264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290258017, states[0] = -94.185753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301455517, states[0] = -94.466208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312640410, states[0] = -37.947921, states[40]= 0.000480
Saving checkpoint... 
Iteration: 323869131, states[0] = -94.467458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335037074, states[0] = 23.412483, states[40]= 0.002926
Saving checkpoint... 
Iteration: 346261643, states[0] = -94.469221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357470092, states[0] = -94.457743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368643254, states[0] = -94.471380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379802875, states[0] = -94.458534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390935825, states[0] = -94.475180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402177079, states[0] = -94.459229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413349628, states[0] = -94.476176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424443333, states[0] = -94.460832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435633409, states[0] = -94.470809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446787906, states[0] = -94.462162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457971337, states[0] = -94.439122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469180587, states[0] = -94.463236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480356917, states[0] = -94.363648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491567274, states[0] = -94.464537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502751473, states[0] = -94.166628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513971855, states[0] = -94.465782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525174037, states[0] = -70.106851, states[40]= 0.000003
Saving checkpoint... 
Iteration: 536196799, states[0] = -94.470262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547296430, states[0] = -94.458463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558522731, states[0] = -94.473569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569724149, states[0] = -94.458851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580951083, states[0] = -94.474823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592173911, states[0] = -94.459135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603379379, states[0] = -94.475800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614624147, states[0] = -94.459433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625809595, states[0] = -94.476197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637006414, states[0] = -94.460228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648164116, states[0] = -94.472800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659410272, states[0] = -94.460961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670606260, states[0] = -94.468134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681808336, states[0] = -94.461836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692981085, states[0] = -94.442487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704051511, states[0] = -94.464614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715272204, states[0] = -94.222652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726453987, states[0] = -94.465914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737651270, states[0] = -47.716719, states[40]= 0.000121
Saving checkpoint... 
Iteration: 748788443, states[0] = -94.468503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759974994, states[0] = -94.457474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771145648, states[0] = -94.471093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782318775, states[0] = -94.458212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793501119, states[0] = -94.473835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804678468, states[0] = -94.458987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815893904, states[0] = -94.475515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827078690, states[0] = -94.459612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838286088, states[0] = -94.476016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849429712, states[0] = -94.460696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860454442, states[0] = -94.432053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871713257, states[0] = -94.462661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882950218, states[0] = -94.430162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894164891, states[0] = -94.463166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905441167, states[0] = -94.425874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916455274, states[0] = -94.465788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927688734, states[0] = -90.000471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938887515, states[0] = -94.466781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950085872, states[0] = 5.116484, states[40]= 0.004846
Saving checkpoint... 
Iteration: 961305950, states[0] = -94.468085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972509079, states[0] = 27.402475, states[40]= 0.064998
Saving checkpoint... 
Iteration: 983755043, states[0] = -94.468952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994951792, states[0] = -94.457446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006193630, states[0] = -94.470055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017270690, states[0] = -94.458336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028528363, states[0] = -94.473198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039774088, states[0] = -94.458305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051027717, states[0] = -94.473197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062272576, states[0] = -94.458301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073531096, states[0] = -94.473121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084715492, states[0] = -94.458610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095969500, states[0] = -94.474225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107211212, states[0] = -94.458622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118442740, states[0] = -94.474654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129706548, states[0] = -94.458636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140955396, states[0] = -94.474436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152230653, states[0] = -94.458484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163536459, states[0] = -94.472969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174574020, states[0] = -94.459448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185799865, states[0] = -94.475871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196835070, states[0] = -94.461302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208031802, states[0] = -94.456177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219188537, states[0] = -94.462726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230369857, states[0] = -94.376258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241557793, states[0] = -94.464231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252785231, states[0] = -94.252326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263941514, states[0] = -94.465790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275094534, states[0] = 0.274567, states[40]= 0.004559
Saving checkpoint... 
Iteration: 1286284482, states[0] = -94.468267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297425604, states[0] = -94.457395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308400299, states[0] = -94.475157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319594195, states[0] = -94.459230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330656109, states[0] = -94.471932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341924639, states[0] = -94.460459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353102611, states[0] = -94.467351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364288164, states[0] = -94.461640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375515335, states[0] = -94.452225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386668577, states[0] = -94.462847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397864072, states[0] = -94.370532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408916655, states[0] = -94.466073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420131934, states[0] = -30.521190, states[40]= 0.001042
Saving checkpoint... 
Iteration: 1431361648, states[0] = -94.466908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442561823, states[0] = 15.572332, states[40]= 0.004211
Saving checkpoint... 
Iteration: 1453745397, states[0] = -94.468858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464958861, states[0] = -94.457148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476154340, states[0] = -94.470529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487244248, states[0] = -94.458218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498482545, states[0] = -94.473771, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.332922
 - CaMKt in component CaMK (millimolar): 0.001075
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.323479
 - nass in component intracellular_ions (millimolar): 6.323562
 - ki in component intracellular_ions (millimolar): 145.608626
 - kss in component intracellular_ions (millimolar): 145.608616
 - cansr in component intracellular_ions (millimolar): 1.538429
 - cajsr in component intracellular_ions (millimolar): 1.538456
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003832
 - hf in component INa (dimensionless): 0.869771
 - hs in component INa (dimensionless): 0.869772
 - j in component INa (dimensionless): 0.869773
 - hsp in component INa (dimensionless): 0.706866
 - jp in component INa (dimensionless): 0.869773
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713911
 - hLp in component INaL (dimensionless): 0.521537
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997818
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999281
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998964
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002800
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001742
 - xs1 in component IKs (dimensionless): 0.021290
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997483
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:26:43 (70608): called boinc_finish(0)

</stderr_txt>
]]>


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