𝕏

Task 55132316

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_2000-conf_781_0
Workunit 26179801
Created 28 Jun 2024, 5:28:33 UTC
Sent 28 Jun 2024, 16:43:07 UTC
Report deadline 1 Jul 2024, 16:43:07 UTC
Received 29 Jun 2024, 5:40:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 15 min 27 sec
CPU time 2 hours 10 min 42 sec
Validate state Valid
Credit 42.25
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 2.35 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_2000-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_2000-conf_781_0_r1189013209_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_2000-conf_781_0_r1189013209_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.207819
     * GNaL_b in INaL: 0.007575
     * Gto_b in Ito: 0.078345
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031451
     * GKs_b in IKs: 0.001907
     * GK1_b in IK1: 0.167097
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 66.371036
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018901
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11182617, states[0] = -83.343746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22395412, states[0] = -94.541621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33603342, states[0] = -94.586367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44772964, states[0] = -94.582783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55984317, states[0] = -94.573260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67072855, states[0] = 12.128459, states[40]= 0.004259
Saving checkpoint... 
Iteration: 78373215, states[0] = -94.476788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89565089, states[0] = -94.559085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100753966, states[0] = -94.569280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111962303, states[0] = -94.565016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123126449, states[0] = -21.610910, states[40]= 0.001596
Saving checkpoint... 
Iteration: 134309538, states[0] = -94.388908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145555507, states[0] = -94.554347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156759617, states[0] = -94.566904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167962543, states[0] = -94.563209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179269992, states[0] = -94.302111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190600789, states[0] = -94.559719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201859836, states[0] = -94.565324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213146749, states[0] = -37.507131, states[40]= 0.000680
Saving checkpoint... 
Iteration: 224288100, states[0] = -94.345315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235606919, states[0] = -94.560064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246905025, states[0] = -94.564112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258211289, states[0] = -94.066015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269296757, states[0] = -94.363343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280603428, states[0] = -94.559572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291920241, states[0] = -94.563609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303207852, states[0] = -93.979183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314487533, states[0] = -94.536961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325730439, states[0] = -94.565725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337023226, states[0] = 27.191088, states[40]= 0.001992
Saving checkpoint... 
Iteration: 348329779, states[0] = -94.419683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359566553, states[0] = -94.554803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370875082, states[0] = -94.564491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381991839, states[0] = -94.561486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393241850, states[0] = -94.216985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404503334, states[0] = -94.541525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415754533, states[0] = -94.565729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426993669, states[0] = -94.561346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438245559, states[0] = -94.229205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449506158, states[0] = -94.542214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460746048, states[0] = -94.565601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471968887, states[0] = -94.561955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483219114, states[0] = -94.131569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494476711, states[0] = -94.532922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505768768, states[0] = -94.565572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517066381, states[0] = 14.825873, states[40]= 0.003871
Saving checkpoint... 
Iteration: 528311991, states[0] = -94.391214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539381423, states[0] = -94.477856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550565965, states[0] = -94.554345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561833971, states[0] = -94.564882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573116415, states[0] = -13.410722, states[40]= 0.001989
Saving checkpoint... 
Iteration: 584422662, states[0] = -94.507607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595653828, states[0] = -94.562801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606921496, states[0] = -94.562953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618210595, states[0] = -94.053104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629471425, states[0] = -94.530724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640745636, states[0] = -94.565252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651802316, states[0] = -94.565109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663029157, states[0] = 26.139109, states[40]= 0.001707
Saving checkpoint... 
Iteration: 674302697, states[0] = -94.374121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685556379, states[0] = -94.552564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696622596, states[0] = -94.560496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707876582, states[0] = -94.563810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719130647, states[0] = -24.800691, states[40]= 0.001693
Saving checkpoint... 
Iteration: 730379035, states[0] = -94.475376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741641618, states[0] = -94.561794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752921532, states[0] = -94.562672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764335300, states[0] = -94.426636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775710390, states[0] = -94.564524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787140842, states[0] = -32.754155, states[40]= 0.001147
Saving checkpoint... 
Iteration: 798537723, states[0] = -94.548934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809955212, states[0] = -94.561680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821353361, states[0] = -94.449159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832770858, states[0] = -94.564941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844135574, states[0] = -28.623605, states[40]= 0.001556
Saving checkpoint... 
Iteration: 855390509, states[0] = -94.484854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866790655, states[0] = -94.564791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878171879, states[0] = -60.150527, states[40]= 0.000023
Saving checkpoint... 
Iteration: 889570171, states[0] = -94.554315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900952218, states[0] = -94.561586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912344091, states[0] = -94.437867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923632695, states[0] = -94.560835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935061902, states[0] = 16.474199, states[40]= 0.003563
Saving checkpoint... 
Iteration: 946457216, states[0] = -94.524403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957839955, states[0] = -94.564025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969282982, states[0] = -94.332229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980580323, states[0] = -94.555535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992027479, states[0] = 26.476866, states[40]= 0.001707
Saving checkpoint... 
Iteration: 1003427346, states[0] = -94.509514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014825863, states[0] = -94.564132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026091161, states[0] = 3.790058, states[40]= 0.004814
Saving checkpoint... 
Iteration: 1037496611, states[0] = -94.538373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048711855, states[0] = -94.564030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060072152, states[0] = 12.563654, states[40]= 0.004229
Saving checkpoint... 
Iteration: 1071416971, states[0] = -94.503207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082822617, states[0] = -94.564046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094236898, states[0] = -94.198652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105675607, states[0] = -94.562849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116984286, states[0] = -94.560285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128361994, states[0] = -94.458053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139746040, states[0] = -94.564296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151117519, states[0] = -14.313748, states[40]= 0.001860
Saving checkpoint... 
Iteration: 1162515966, states[0] = -94.543384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173907785, states[0] = -94.562203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185205917, states[0] = -93.879937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196619110, states[0] = -94.559246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208064248, states[0] = 15.622521, states[40]= 0.003727
Saving checkpoint... 
Iteration: 1219497172, states[0] = -94.538190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230871712, states[0] = -94.562907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242192448, states[0] = -86.722355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253529723, states[0] = -94.546393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264849175, states[0] = -94.563278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276228037, states[0] = -94.166472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287635173, states[0] = -94.560312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299020535, states[0] = 27.517464, states[40]= 0.002726
Saving checkpoint... 
Iteration: 1310417585, states[0] = -94.503130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321738008, states[0] = -94.563885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333155960, states[0] = -45.319668, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1344454037, states[0] = -94.522252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355798243, states[0] = -94.563793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367191824, states[0] = -85.841822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378589085, states[0] = -94.555861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389983252, states[0] = -94.559790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401387220, states[0] = -94.481123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412807114, states[0] = -94.563599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424218886, states[0] = -94.128595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435388325, states[0] = -94.481967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446808276, states[0] = -94.563521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458207764, states[0] = -93.973210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469643102, states[0] = -94.560490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481079091, states[0] = 9.618121, states[40]= 0.004572
Saving checkpoint... 
Iteration: 1492531274, states[0] = -94.546267, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.435041
 - CaMKt in component CaMK (millimolar): 0.004392
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.671278
 - nass in component intracellular_ions (millimolar): 6.671366
 - ki in component intracellular_ions (millimolar): 145.233216
 - kss in component intracellular_ions (millimolar): 145.233201
 - cansr in component intracellular_ions (millimolar): 1.625324
 - cajsr in component intracellular_ions (millimolar): 1.624611
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003793
 - hf in component INa (dimensionless): 0.871661
 - hs in component INa (dimensionless): 0.871662
 - j in component INa (dimensionless): 0.871668
 - hsp in component INa (dimensionless): 0.710338
 - jp in component INa (dimensionless): 0.871672
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.716529
 - hLp in component INaL (dimensionless): 0.507170
 - a in component Ito (dimensionless): 0.000643
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.889685
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.929656
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974245
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002935
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.101843
 - xs1 in component IKs (dimensionless): 0.128922
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997457
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:35:20 (71646): called boinc_finish(0)

</stderr_txt>
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