𝕏

Task 55130174

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT-conf_778_0
Workunit 26178730
Created 28 Jun 2024, 5:27:30 UTC
Sent 28 Jun 2024, 16:24:39 UTC
Report deadline 1 Jul 2024, 16:24:39 UTC
Received 28 Jun 2024, 19:41:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217567
Run time 1 hours 31 min 33 sec
CPU time 1 hours 15 min 43 sec
Validate state Valid
Credit 40.52
Device peak FLOPS 4.28 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.10 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.14.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT-conf_778.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT-conf_778_0_r1029101035_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT-conf_778_0_r1029101035_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 95.610461
     * GNaL_b in INaL: 0.004807
     * Gto_b in Ito: 0.091053
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032387
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161124
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 70.097309
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019103
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10984149, states[0] = -94.779284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22461164, states[0] = -94.738209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32800356, states[0] = -94.600950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43020579, states[0] = 26.377368, states[40]= 0.002126
Saving checkpoint... 
Iteration: 53750181, states[0] = -94.484854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63460303, states[0] = -94.725052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74372265, states[0] = -94.679593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85525859, states[0] = 25.266063, states[40]= 0.001145
Saving checkpoint... 
Iteration: 96192749, states[0] = -94.256408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106716605, states[0] = -94.367824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116185697, states[0] = -94.194663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126106678, states[0] = -20.741322, states[40]= 0.001167
Saving checkpoint... 
Iteration: 136477176, states[0] = -94.729943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147887475, states[0] = -94.690563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158776242, states[0] = -94.549750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168495271, states[0] = -94.734198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178713697, states[0] = -94.355526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188998045, states[0] = -94.734709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199200461, states[0] = -94.296262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210602592, states[0] = -16.597551, states[40]= 0.001449
Saving checkpoint... 
Iteration: 220055472, states[0] = 14.732540, states[40]= 0.002556
Saving checkpoint... 
Iteration: 230487930, states[0] = -94.732255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240007941, states[0] = 26.943694, states[40]= 0.099959
Saving checkpoint... 
Iteration: 251338569, states[0] = -94.647538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260815085, states[0] = -94.617927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272344385, states[0] = -94.653702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282332406, states[0] = -94.640328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292412280, states[0] = -94.704612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303262135, states[0] = -94.516012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314603538, states[0] = -17.562857, states[40]= 0.001357
Saving checkpoint... 
Iteration: 325418006, states[0] = -94.707352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334730381, states[0] = -94.419700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345916241, states[0] = -94.706381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355915139, states[0] = -94.705780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366483465, states[0] = -94.730537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377024961, states[0] = 25.485363, states[40]= 0.001196
Saving checkpoint... 
Iteration: 387625845, states[0] = -39.642329, states[40]= 0.000349
Saving checkpoint... 
Iteration: 398528525, states[0] = 24.547749, states[40]= 0.001098
Saving checkpoint... 
Iteration: 408842070, states[0] = -94.650614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418180496, states[0] = -94.055086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429388024, states[0] = -94.689647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439355722, states[0] = -94.664086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450182026, states[0] = -94.114474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460380965, states[0] = -94.684624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469883934, states[0] = -94.686674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480120149, states[0] = -34.019816, states[40]= 0.000648
Saving checkpoint... 
Iteration: 489764848, states[0] = -94.521897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501524907, states[0] = 25.498476, states[40]= 0.001200
Saving checkpoint... 
Iteration: 511899667, states[0] = -94.696576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521738770, states[0] = -94.447509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531351184, states[0] = -94.659339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542866863, states[0] = -94.673370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553351073, states[0] = -94.659128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565106242, states[0] = -20.303834, states[40]= 0.001184
Saving checkpoint... 
Iteration: 574578765, states[0] = 3.393120, states[40]= 0.004128
Saving checkpoint... 
Iteration: 585876656, states[0] = -94.680879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596869448, states[0] = -94.675227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608686238, states[0] = -94.199645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619488312, states[0] = -94.730524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629015026, states[0] = 26.925576, states[40]= 0.009483
Saving checkpoint... 
Iteration: 638952185, states[0] = -94.720040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648870030, states[0] = -94.675450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659040374, states[0] = 20.624598, states[40]= 0.001524
Saving checkpoint... 
Iteration: 669814050, states[0] = -94.614519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681475294, states[0] = -94.726938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692623950, states[0] = -37.760585, states[40]= 0.000437
Saving checkpoint... 
Iteration: 703330195, states[0] = -94.635698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713296601, states[0] = -94.586713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724461312, states[0] = -94.722649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735485101, states[0] = -94.729210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746208860, states[0] = -94.332026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755619250, states[0] = -33.136939, states[40]= 0.000702
Saving checkpoint... 
Iteration: 766422771, states[0] = -94.707565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776389815, states[0] = -94.689200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786398818, states[0] = -94.694782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797292013, states[0] = -94.578153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808410251, states[0] = -94.701122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818724031, states[0] = -94.393940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829466919, states[0] = -94.723868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840361712, states[0] = -94.667592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850091147, states[0] = -5.462256, states[40]= 0.003432
Saving checkpoint... 
Iteration: 861107991, states[0] = -22.057124, states[40]= 0.001128
Saving checkpoint... 
Iteration: 871146306, states[0] = -60.787346, states[40]= 0.000015
Saving checkpoint... 
Iteration: 882310881, states[0] = -94.608881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891971740, states[0] = -94.724968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901981369, states[0] = -94.727499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913606858, states[0] = -20.922050, states[40]= 0.001161
Saving checkpoint... 
Iteration: 924970811, states[0] = -94.724550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935801976, states[0] = -94.594724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947255086, states[0] = -94.494393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957953860, states[0] = -94.719118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967963137, states[0] = -94.722075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979391076, states[0] = -94.689066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989241666, states[0] = -94.454613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000463085, states[0] = -94.721907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010226050, states[0] = -94.400650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020227621, states[0] = -94.406427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031537912, states[0] = 21.510344, states[40]= 0.001399
Saving checkpoint... 
Iteration: 1042088345, states[0] = -3.145914, states[40]= 0.003807
Saving checkpoint... 
Iteration: 1052488513, states[0] = -94.728541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061825726, states[0] = -94.628463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073092851, states[0] = -6.971861, states[40]= 0.003139
Saving checkpoint... 
Iteration: 1084291878, states[0] = -94.576551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094461844, states[0] = -94.721080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104569793, states[0] = 8.266023, states[40]= 0.003681
Saving checkpoint... 
Iteration: 1114873690, states[0] = -94.676138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124987315, states[0] = -94.727917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135684080, states[0] = -94.162775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145648624, states[0] = -63.338895, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1154804933, states[0] = -94.598456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164593182, states[0] = -7.273473, states[40]= 0.003078
Saving checkpoint... 
Iteration: 1175338201, states[0] = -94.642780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185532329, states[0] = 23.397512, states[40]= 0.001173
Saving checkpoint... 
Iteration: 1195343289, states[0] = -94.648207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205165218, states[0] = -86.260517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214566047, states[0] = 10.078510, states[40]= 0.003407
Saving checkpoint... 
Iteration: 1224194612, states[0] = -94.261812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234406397, states[0] = -94.697033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245156438, states[0] = -72.977188, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1256013480, states[0] = 26.933855, states[40]= 0.015604
Saving checkpoint... 
Iteration: 1267172715, states[0] = -92.810235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278478257, states[0] = -94.724929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289112947, states[0] = -26.957155, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1298098897, states[0] = -12.826799, states[40]= 0.001976
Saving checkpoint... 
Iteration: 1308492985, states[0] = -94.728368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320023228, states[0] = 25.879611, states[40]= 0.001387
Saving checkpoint... 
Iteration: 1330520890, states[0] = 26.329099, states[40]= 0.001980
Saving checkpoint... 
Iteration: 1341572967, states[0] = 6.639942, states[40]= 0.003883
Saving checkpoint... 
Iteration: 1351954801, states[0] = -94.717588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362486127, states[0] = -94.726519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372681614, states[0] = -94.095819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382879908, states[0] = -94.679527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394812945, states[0] = -94.609501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405448572, states[0] = -94.715171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415696239, states[0] = -94.269542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426087433, states[0] = -2.435809, states[40]= 0.003899
Saving checkpoint... 
Iteration: 1435242179, states[0] = -94.454115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445793179, states[0] = -94.577203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456374635, states[0] = -94.675258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465635751, states[0] = -49.704138, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1476677432, states[0] = -93.825706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486219682, states[0] = -94.373808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496512501, states[0] = 26.908890, states[40]= 0.021543
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.604859
 - CaMKt in component CaMK (millimolar): 0.013046
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.848107
 - nass in component intracellular_ions (millimolar): 6.848205
 - ki in component intracellular_ions (millimolar): 145.021669
 - kss in component intracellular_ions (millimolar): 145.021649
 - cansr in component intracellular_ions (millimolar): 1.695365
 - cajsr in component intracellular_ions (millimolar): 1.653563
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003729
 - hf in component INa (dimensionless): 0.874751
 - hs in component INa (dimensionless): 0.874743
 - j in component INa (dimensionless): 0.874687
 - hsp in component INa (dimensionless): 0.715990
 - jp in component INa (dimensionless): 0.874649
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.699864
 - hLp in component INaL (dimensionless): 0.437329
 - a in component Ito (dimensionless): 0.000636
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.612559
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.683404
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.918854
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999847
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003227
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.360880
 - xs1 in component IKs (dimensionless): 0.263094
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997414
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:41:39 (7777): called boinc_finish(0)

</stderr_txt>
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