𝕏

Task 55128227

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_333-conf_276_0
Workunit 26177758
Created 28 Jun 2024, 5:26:37 UTC
Sent 28 Jun 2024, 16:05:40 UTC
Report deadline 1 Jul 2024, 16:05:40 UTC
Received 29 Jun 2024, 11:30:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223172
Run time 3 hours 15 min
CPU time 2 hours 39 min 26 sec
Validate state Valid
Credit 47.60
Device peak FLOPS 2.74 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.21 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_333-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_333-conf_276_0_r1691655841_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_333-conf_276_0_r1691655841_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.331028
     * GNaL_b in INaL: 0.006450
     * Gto_b in Ito: 0.076240
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029976
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.157307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.518163
     * GKb_b in IKb: 0.003846
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041223
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10048248, states[0] = 13.650288, states[40]= 0.000870
Saving checkpoint... 
Iteration: 19741365, states[0] = -9.660498, states[40]= 0.000890
Saving checkpoint... 
Iteration: 29822323, states[0] = -84.923050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39648649, states[0] = -84.862996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49721629, states[0] = 6.177482, states[40]= 0.000110
Saving checkpoint... 
Iteration: 59505029, states[0] = 29.769985, states[40]= 0.045616
Saving checkpoint... 
Iteration: 69687698, states[0] = 26.029860, states[40]= 0.000091
Saving checkpoint... 
Iteration: 79540769, states[0] = 13.985337, states[40]= 0.000016
Saving checkpoint... 
Iteration: 89567807, states[0] = -12.880784, states[40]= 0.000289
Saving checkpoint... 
Iteration: 99315102, states[0] = -84.996779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109340778, states[0] = 29.504320, states[40]= 0.002919
Saving checkpoint... 
Iteration: 118975006, states[0] = -84.940654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127855525, states[0] = 22.256249, states[40]= 0.000008
Saving checkpoint... 
Iteration: 137492133, states[0] = 28.678035, states[40]= 0.301686
Saving checkpoint... 
Iteration: 147239146, states[0] = -27.625634, states[40]= 0.000271
Saving checkpoint... 
Iteration: 156077372, states[0] = -35.212879, states[40]= 0.000253
Saving checkpoint... 
Iteration: 165895601, states[0] = -16.179659, states[40]= 0.000248
Saving checkpoint... 
Iteration: 175617566, states[0] = -84.135583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185276095, states[0] = -81.140843, states[40]= 0.000002
Saving checkpoint... 
Iteration: 195504917, states[0] = 27.467125, states[40]= 0.000317
Saving checkpoint... 
Iteration: 204838577, states[0] = 26.926377, states[40]= 0.000202
Saving checkpoint... 
Iteration: 215092564, states[0] = -62.629560, states[40]= 0.000025
Saving checkpoint... 
Iteration: 224379277, states[0] = -2.469224, states[40]= 0.000234
Saving checkpoint... 
Iteration: 234137239, states[0] = -85.023992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243976963, states[0] = 33.235948, states[40]= 1.115972
Saving checkpoint... 
Iteration: 254347137, states[0] = 19.792332, states[40]= 0.000004
Saving checkpoint... 
Iteration: 264071074, states[0] = -41.005607, states[40]= 0.000187
Saving checkpoint... 
Iteration: 273881035, states[0] = -10.908652, states[40]= 0.000282
Saving checkpoint... 
Iteration: 283619741, states[0] = -84.852769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293881499, states[0] = -14.360353, states[40]= 0.000260
Saving checkpoint... 
Iteration: 302641693, states[0] = 28.867976, states[40]= 0.372754
Saving checkpoint... 
Iteration: 310812929, states[0] = 29.570963, states[40]= 0.051305
Saving checkpoint... 
Iteration: 319642585, states[0] = 28.843306, states[40]= 0.145624
Saving checkpoint... 
Iteration: 328297793, states[0] = -85.053990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337020662, states[0] = 9.882029, states[40]= 0.000037
Saving checkpoint... 
Iteration: 340343784, states[0] = 16.590334, states[40]= 0.000007
Saving checkpoint... 
Iteration: 344929207, states[0] = -82.670367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350515271, states[0] = 12.747633, states[40]= 0.000019
Saving checkpoint... 
Iteration: 359072672, states[0] = -55.197397, states[40]= 0.000055
Saving checkpoint... 
Iteration: 364812949, states[0] = 29.862958, states[40]= 0.006750
Saving checkpoint... 
Iteration: 369524903, states[0] = 3.913233, states[40]= 0.000114
Saving checkpoint... 
Iteration: 375139630, states[0] = 29.527141, states[40]= 0.055287
Saving checkpoint... 
Iteration: 381383300, states[0] = -28.862063, states[40]= 0.000273
Saving checkpoint... 
Iteration: 386742030, states[0] = -62.565522, states[40]= 0.000025
Saving checkpoint... 
Iteration: 391374721, states[0] = -18.537176, states[40]= 0.000238
Saving checkpoint... 
Iteration: 396931370, states[0] = -84.442382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401887670, states[0] = -37.227190, states[40]= 0.000232
Saving checkpoint... 
Iteration: 405353522, states[0] = 4.886633, states[40]= 0.000098
Saving checkpoint... 
Iteration: 409712557, states[0] = -27.204647, states[40]= 0.000267
Saving checkpoint... 
Iteration: 413823241, states[0] = 24.230016, states[40]= 0.000028
Saving checkpoint... 
Iteration: 417920370, states[0] = -81.759613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423045181, states[0] = -28.035902, states[40]= 0.000271
Saving checkpoint... 
Iteration: 428304063, states[0] = 29.957117, states[40]= 0.017367
Saving checkpoint... 
Iteration: 433094159, states[0] = -84.415490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438934272, states[0] = -84.775662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444400224, states[0] = -58.838108, states[40]= 0.000038
Saving checkpoint... 
Iteration: 450480958, states[0] = 26.806082, states[40]= 0.000182
Saving checkpoint... 
Iteration: 455595750, states[0] = -84.661681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462264162, states[0] = -84.744905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 468743103, states[0] = -76.036722, states[40]= 0.000004
Saving checkpoint... 
Iteration: 474411485, states[0] = -78.860094, states[40]= 0.000003
Saving checkpoint... 
Iteration: 481570485, states[0] = -69.240689, states[40]= 0.000011
Saving checkpoint... 
Iteration: 490048917, states[0] = -41.557811, states[40]= 0.000181
Saving checkpoint... 
Iteration: 497698339, states[0] = -19.810727, states[40]= 0.000236
Saving checkpoint... 
Iteration: 503997486, states[0] = 14.393427, states[40]= 0.000012
Saving checkpoint... 
Iteration: 510638884, states[0] = 27.948510, states[40]= 0.000486
Saving checkpoint... 
Iteration: 519072292, states[0] = -77.192690, states[40]= 0.000004
Saving checkpoint... 
Iteration: 525413650, states[0] = -83.608371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531383744, states[0] = -48.698761, states[40]= 0.000103
Saving checkpoint... 
Iteration: 537911185, states[0] = -83.206449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544928788, states[0] = -84.866907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552241169, states[0] = -82.301045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558708945, states[0] = -41.846548, states[40]= 0.000178
Saving checkpoint... 
Iteration: 567969072, states[0] = 26.869370, states[40]= 0.000191
Saving checkpoint... 
Iteration: 576318678, states[0] = 17.537257, states[40]= 0.000005
Saving checkpoint... 
Iteration: 584527687, states[0] = -26.231476, states[40]= 0.000263
Saving checkpoint... 
Iteration: 593251077, states[0] = -84.736707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602485038, states[0] = 16.083039, states[40]= 0.000008
Saving checkpoint... 
Iteration: 610234407, states[0] = -81.689850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619837859, states[0] = -0.462993, states[40]= 0.000197
Saving checkpoint... 
Iteration: 629009952, states[0] = -7.866767, states[40]= 0.000285
Saving checkpoint... 
Iteration: 638658167, states[0] = 9.142561, states[40]= 0.000044
Saving checkpoint... 
Iteration: 647967779, states[0] = 23.555421, states[40]= 0.000018
Saving checkpoint... 
Iteration: 657088813, states[0] = -84.924382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665797400, states[0] = 24.566256, states[40]= 0.000035
Saving checkpoint... 
Iteration: 672572328, states[0] = -84.560227, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679860566, states[0] = -38.095199, states[40]= 0.000222
Saving checkpoint... 
Iteration: 685846529, states[0] = -20.271331, states[40]= 0.000236
Saving checkpoint... 
Iteration: 694396643, states[0] = -83.560967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701011311, states[0] = -19.757304, states[40]= 0.000236
Saving checkpoint... 
Iteration: 705546254, states[0] = -66.499939, states[40]= 0.000015
Saving checkpoint... 
Iteration: 713259688, states[0] = -85.034177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721969664, states[0] = 18.225877, states[40]= 0.000004
Saving checkpoint... 
Iteration: 730390333, states[0] = -82.454867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738223329, states[0] = -82.682886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746702690, states[0] = -57.953052, states[40]= 0.000041
Saving checkpoint... 
Iteration: 755201517, states[0] = -57.521299, states[40]= 0.000043
Saving checkpoint... 
Iteration: 764176988, states[0] = -27.017874, states[40]= 0.000266
Saving checkpoint... 
Iteration: 772668952, states[0] = -17.146473, states[40]= 0.000242
Saving checkpoint... 
Iteration: 782718984, states[0] = -82.728385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 792480583, states[0] = 5.643398, states[40]= 0.000086
Saving checkpoint... 
Iteration: 802588942, states[0] = 33.084819, states[40]= 0.969476
Saving checkpoint... 
Iteration: 812348874, states[0] = -40.075883, states[40]= 0.000199
Saving checkpoint... 
Iteration: 822545427, states[0] = -80.838735, states[40]= 0.000002
Saving checkpoint... 
Iteration: 832315962, states[0] = 0.199390, states[40]= 0.000185
Saving checkpoint... 
Iteration: 842502926, states[0] = -27.596676, states[40]= 0.000269
Saving checkpoint... 
Iteration: 851682548, states[0] = -45.502968, states[40]= 0.000135
Saving checkpoint... 
Iteration: 858706522, states[0] = -78.946401, states[40]= 0.000003
Saving checkpoint... 
Iteration: 867222880, states[0] = -84.694572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875956318, states[0] = 16.958937, states[40]= 0.000006
Saving checkpoint... 
Iteration: 885525077, states[0] = -61.937782, states[40]= 0.000027
Saving checkpoint... 
Iteration: 894460188, states[0] = 13.229164, states[40]= 0.000017
Saving checkpoint... 
Iteration: 901303092, states[0] = 5.598411, states[40]= 0.000087
Saving checkpoint... 
Iteration: 909807726, states[0] = 0.683275, states[40]= 0.000175
Saving checkpoint... 
Iteration: 919241121, states[0] = -85.042181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928045172, states[0] = -84.425275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936269304, states[0] = 25.105743, states[40]= 0.000050
Saving checkpoint... 
Iteration: 943412075, states[0] = 28.620508, states[40]= 0.248109
Saving checkpoint... 
Iteration: 952551875, states[0] = -84.792348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960677030, states[0] = -52.356672, states[40]= 0.000073
Saving checkpoint... 
Iteration: 967956485, states[0] = 10.682591, states[40]= 0.000031
Saving checkpoint... 
Iteration: 977861477, states[0] = -79.148243, states[40]= 0.000002
Saving checkpoint... 
Iteration: 986722329, states[0] = -84.901065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 995316581, states[0] = -21.630889, states[40]= 0.000238
Saving checkpoint... 
Iteration: 1003262136, states[0] = 25.340679, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1010490504, states[0] = -33.347117, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1018860680, states[0] = -81.947802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028045033, states[0] = -84.800748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037030214, states[0] = -83.830854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046671166, states[0] = -55.901854, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1056225333, states[0] = -85.012314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065521099, states[0] = -80.774988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1075094388, states[0] = 22.110827, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1084041182, states[0] = -84.827432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093387084, states[0] = -84.997153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102697170, states[0] = -84.594112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112319231, states[0] = -40.517311, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1121610588, states[0] = 8.615284, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1131974913, states[0] = -28.822018, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1142180978, states[0] = -81.454171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152776888, states[0] = 6.467136, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1163311250, states[0] = -36.819092, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1173962686, states[0] = -17.872135, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1184573108, states[0] = 27.303367, states[40]= 0.000270
Saving checkpoint... 
Iteration: 1195237877, states[0] = 27.648645, states[40]= 0.000365
Saving checkpoint... 
Iteration: 1205893951, states[0] = 29.979434, states[40]= 0.011993
Saving checkpoint... 
Iteration: 1216631593, states[0] = -26.788648, states[40]= 0.000264
Saving checkpoint... 
Iteration: 1227083298, states[0] = 19.751421, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1237809146, states[0] = -43.627742, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1248383797, states[0] = 29.051695, states[40]= 0.109622
Saving checkpoint... 
Iteration: 1259027679, states[0] = -84.874301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269764269, states[0] = 7.201535, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1280279341, states[0] = -9.409003, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1291068149, states[0] = 24.609054, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1301690045, states[0] = -84.870863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312457690, states[0] = -29.899756, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1323077689, states[0] = 17.329866, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1333876713, states[0] = 29.449337, states[40]= 0.063351
Saving checkpoint... 
Iteration: 1344517578, states[0] = -84.847276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355301825, states[0] = -49.241419, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1365863964, states[0] = 23.317372, states[40]= 0.039964
Saving checkpoint... 
Iteration: 1375332832, states[0] = -84.300871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385319407, states[0] = -77.560462, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1396131521, states[0] = -49.806625, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1406730964, states[0] = 20.361736, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1417485995, states[0] = -80.806779, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1428067023, states[0] = 17.437596, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1438442585, states[0] = -26.559742, states[40]= 0.000263
Saving checkpoint... 
Iteration: 1449196366, states[0] = 28.869290, states[40]= 0.141085
Saving checkpoint... 
Iteration: 1459768189, states[0] = -18.899652, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1470438478, states[0] = -25.337792, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1481041247, states[0] = 28.193035, states[40]= 0.000601
Saving checkpoint... 
Iteration: 1491887624, states[0] = 21.224340, states[40]= 0.000005
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.884470
 - CaMKt in component CaMK (millimolar): 0.217049
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.295450
 - nass in component intracellular_ions (millimolar): 7.295801
 - ki in component intracellular_ions (millimolar): 143.818349
 - kss in component intracellular_ions (millimolar): 143.818315
 - cansr in component intracellular_ions (millimolar): 3.316559
 - cajsr in component intracellular_ions (millimolar): 1.885764
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009920
 - hf in component INa (dimensionless): 0.585748
 - hs in component INa (dimensionless): 0.584655
 - j in component INa (dimensionless): 0.548654
 - hsp in component INa (dimensionless): 0.332048
 - jp in component INa (dimensionless): 0.502394
 - mL in component INaL (dimensionless): 0.000332
 - hL in component INaL (dimensionless): 0.173648
 - hLp in component INaL (dimensionless): 0.070127
 - a in component Ito (dimensionless): 0.001225
 - iF in component Ito (dimensionless): 0.999242
 - iS in component Ito (dimensionless): 0.126124
 - ap in component Ito (dimensionless): 0.000624
 - iFp in component Ito (dimensionless): 0.999243
 - iSp in component Ito (dimensionless): 0.140144
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.668809
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.924485
 - jca in component ICaL (dimensionless): 0.907043
 - ffp in component ICaL (dimensionless): 0.998590
 - fcafp in component ICaL (dimensionless): 0.999927
 - nca in component ICaL (dimensionless): 0.041961
 - xrf in component IKr (dimensionless): 0.112760
 - xrs in component IKr (dimensionless): 0.878239
 - xs1 in component IKs (dimensionless): 0.577007
 - xs2 in component IKs (dimensionless): 0.008693
 - xk1 in component IK1 (dimensionless): 0.996731
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:30:04 (12168): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge