𝕏

Task 55125871

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_4000-conf_373_1
Workunit 26176581
Created 28 Jun 2024, 5:25:29 UTC
Sent 28 Jun 2024, 15:49:15 UTC
Report deadline 1 Jul 2024, 15:49:15 UTC
Received 29 Jun 2024, 5:58:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216581
Run time 57 min 8 sec
CPU time 45 min 38 sec
Validate state Valid
Credit 42.19
Device peak FLOPS 5.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.51 MB
Peak swap size 1.54 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_4000-conf_373.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_4000-conf_373_1_r861021243_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_4000-conf_373_1_r861021243_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.153868
     * GNaL_b in INaL: 0.005575
     * Gto_b in Ito: 0.071808
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033649
     * GKs_b in IKs: 0.001965
     * GK1_b in IK1: 0.164831
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 66.976441
     * GKb_b in IKb: 0.003697
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047162
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9846558, states[0] = -94.181489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22530016, states[0] = -94.138219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35279708, states[0] = -94.185189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48156081, states[0] = -5.276096, states[40]= 0.000435
Saving checkpoint... 
Iteration: 60537248, states[0] = -94.175817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70909918, states[0] = -94.224920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81137794, states[0] = -94.224214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93701684, states[0] = -94.215845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106393234, states[0] = -94.058492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118991419, states[0] = -94.241497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131461451, states[0] = -94.230209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141052404, states[0] = -94.243135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153170061, states[0] = -94.240652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170110700, states[0] = 10.582766, states[40]= 0.000027
Saving checkpoint... 
Iteration: 183215254, states[0] = -94.240895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195551121, states[0] = -94.232637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207435936, states[0] = -94.235410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217815159, states[0] = -94.228313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229755946, states[0] = -94.229256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241609250, states[0] = -94.231817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253844511, states[0] = -94.227918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265686094, states[0] = -94.230317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277985604, states[0] = -94.226021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290259886, states[0] = -88.898708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302301768, states[0] = -93.795294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314077010, states[0] = 23.299158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323715950, states[0] = -94.229319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335865968, states[0] = -94.226953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347860043, states[0] = -94.226907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360298977, states[0] = -93.781700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372210726, states[0] = -38.457322, states[40]= 0.001631
Saving checkpoint... 
Iteration: 384431211, states[0] = -94.127239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396267357, states[0] = -93.207071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408399024, states[0] = -94.079965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420288787, states[0] = -93.730671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432629877, states[0] = -94.236349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444845102, states[0] = -94.249300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456578354, states[0] = -94.223909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 468898308, states[0] = -94.248416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480750896, states[0] = -94.247594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490777125, states[0] = -94.248275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503131704, states[0] = -94.241575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515327889, states[0] = -94.235645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 527495832, states[0] = -94.231353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539422801, states[0] = -94.232927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551876051, states[0] = -94.224437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564266192, states[0] = -92.988774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576012831, states[0] = 32.012072, states[40]= -0.000000
Saving checkpoint... 
Iteration: 588440646, states[0] = -94.136125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600626483, states[0] = -94.233854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612892681, states[0] = -94.246902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625019586, states[0] = -94.243667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637630519, states[0] = -94.227363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648210923, states[0] = -38.587335, states[40]= 0.001609
Saving checkpoint... 
Iteration: 660494254, states[0] = -94.182597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669645841, states[0] = -94.226722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 681791327, states[0] = -94.224173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693742193, states[0] = -94.224800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705889000, states[0] = -94.222545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707124157, states[0] = -94.239532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719471262, states[0] = -94.229765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731375168, states[0] = -94.231978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743912365, states[0] = -94.221823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755865601, states[0] = -94.222295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765369984, states[0] = -94.231735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770788064, states[0] = -94.245369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782727048, states[0] = -94.243104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794532789, states[0] = -94.202863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806367990, states[0] = -94.013080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817992861, states[0] = -94.220052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 829794902, states[0] = -94.222468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841696835, states[0] = -94.223898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851266431, states[0] = -94.233617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863278514, states[0] = -94.233137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874993720, states[0] = -94.241628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 886856689, states[0] = -94.244295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898974279, states[0] = -94.241894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909154558, states[0] = -94.236332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921153219, states[0] = -94.236240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932872674, states[0] = -94.243619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942031939, states[0] = 34.570013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953979053, states[0] = -94.218686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965680265, states[0] = -94.222800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978216680, states[0] = -42.695920, states[40]= 0.001012
Saving checkpoint... 
Iteration: 990010405, states[0] = 30.742662, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1001852477, states[0] = -94.219724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013580271, states[0] = -94.224136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025912346, states[0] = -94.218672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037810050, states[0] = -94.219919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049703226, states[0] = -94.221465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061332588, states[0] = -94.229422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070741113, states[0] = -94.240602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080216187, states[0] = -42.328862, states[40]= 0.001058
Saving checkpoint... 
Iteration: 1092324784, states[0] = -93.881599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102040389, states[0] = 33.733859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113889855, states[0] = -94.217974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126099124, states[0] = 14.977912, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1137884725, states[0] = -94.217772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149942773, states[0] = -94.216915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161944366, states[0] = -94.216762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174100952, states[0] = 14.273349, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1186117755, states[0] = 7.760633, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1198285843, states[0] = -93.706112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210374220, states[0] = -94.022672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222218559, states[0] = -44.091906, states[40]= 0.000855
Saving checkpoint... 
Iteration: 1233864464, states[0] = -94.216967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242805421, states[0] = -94.240328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254990206, states[0] = -94.237484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266717972, states[0] = -94.237158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1278682667, states[0] = -94.234154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290805306, states[0] = -94.239795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302331626, states[0] = -93.903542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314196666, states[0] = -29.870504, states[40]= 0.003215
Saving checkpoint... 
Iteration: 1326250055, states[0] = -72.871509, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1338248156, states[0] = -70.307661, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1350262852, states[0] = -91.628431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362160314, states[0] = -12.630061, states[40]= 0.000434
Saving checkpoint... 
Iteration: 1371255489, states[0] = -94.228129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383115614, states[0] = -94.232257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395240379, states[0] = -94.228303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404823669, states[0] = -94.238625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414142514, states[0] = -2.593839, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1426110800, states[0] = 10.466502, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1438503460, states[0] = -94.179830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450632497, states[0] = -94.225452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462956855, states[0] = -94.236056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474790045, states[0] = -94.237549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487018639, states[0] = -94.234077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499129844, states[0] = -94.230516, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.088319
 - CaMKt in component CaMK (millimolar): 0.002470
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.939918
 - nass in component intracellular_ions (millimolar): 7.940068
 - ki in component intracellular_ions (millimolar): 143.855928
 - kss in component intracellular_ions (millimolar): 143.855913
 - cansr in component intracellular_ions (millimolar): 1.804842
 - cajsr in component intracellular_ions (millimolar): 1.806585
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003928
 - hf in component INa (dimensionless): 0.865151
 - hs in component INa (dimensionless): 0.865152
 - j in component INa (dimensionless): 0.865154
 - hsp in component INa (dimensionless): 0.698472
 - jp in component INa (dimensionless): 0.865156
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707215
 - hLp in component INaL (dimensionless): 0.512672
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.990407
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.996093
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994952
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004263
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008855
 - xs1 in component IKs (dimensionless): 0.052835
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997543
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:49:13 (13292): called boinc_finish(0)

</stderr_txt>
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