𝕏

Task 55120534

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1
Workunit 26173914
Created 28 Jun 2024, 5:23:07 UTC
Sent 28 Jun 2024, 15:01:04 UTC
Report deadline 2 Jul 2024, 0:37:04 UTC
Received 2 Jul 2024, 10:57:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237469
Run time 1 hours 27 min 35 sec
CPU time 1 hours 24 min 36 sec
Validate state Valid
Credit 62.04
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.21 MB
Peak swap size 5.28 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.295567
     * GNaL_b in INaL: 0.005570
     * Gto_b in Ito: 0.080653
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029661
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.153858
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 73.740349
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045916
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17871818, states[0] = -95.163041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36203884, states[0] = -94.942705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61845463, states[0] = -95.066384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75674915, states[0] = -94.293780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94899872, states[0] = -95.070864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120607183, states[0] = -22.027537, states[40]= 0.000845
Saving checkpoint... 
Iteration: 145816712, states[0] = -95.024186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172687337, states[0] = -94.827733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198195616, states[0] = -94.862576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223969376, states[0] = -95.076387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249707705, states[0] = -94.887940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275428987, states[0] = -95.068328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301264272, states[0] = -94.974892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327014375, states[0] = 22.862607, states[40]= 0.020592
Saving checkpoint... 
Iteration: 352697728, states[0] = -94.867075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378424850, states[0] = -95.067236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404397474, states[0] = -95.059674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430493915, states[0] = -95.079536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456264859, states[0] = -94.975453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482051381, states[0] = 12.173602, states[40]= 0.004907
Saving checkpoint... 
Iteration: 507644096, states[0] = -57.500757, states[40]= 0.000007
Saving checkpoint... 
Iteration: 533320755, states[0] = -95.024316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551699736, states[0] = -94.871433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577444535, states[0] = -95.071475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603202102, states[0] = -94.876404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629741665, states[0] = -94.945342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656306794, states[0] = -95.014483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683019344, states[0] = 22.059137, states[40]= 0.010444
Saving checkpoint... 
Iteration: 709944796, states[0] = -95.071452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736636923, states[0] = -49.973626, states[40]= 0.000027
Saving checkpoint... 
Iteration: 763254454, states[0] = -94.962681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789887135, states[0] = -95.056063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816523650, states[0] = 21.165142, states[40]= 0.007659
Saving checkpoint... 
Iteration: 843153865, states[0] = -68.806153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869763542, states[0] = -94.973696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895513955, states[0] = 22.925784, states[40]= 0.022224
Saving checkpoint... 
Iteration: 908577814, states[0] = 0.836454, states[40]= 0.004249


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.295567
     * GNaL_b in INaL: 0.005570
     * Gto_b in Ito: 0.080653
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029661
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.153858
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 73.740349
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045916
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 908577814
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 0.836454 (After loading)
 - states[40]: 0.004249 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 928332543, states[0] = -95.031347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954844931, states[0] = -95.038106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981251875, states[0] = -94.959223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007663795, states[0] = -83.836592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030013208, states[0] = 23.040552, states[40]= 0.025626
Saving checkpoint... 
Iteration: 1053451266, states[0] = -95.072521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078388699, states[0] = -95.056434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102833474, states[0] = -95.031786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125504013, states[0] = 31.654418, states[40]= 0.143610
Saving checkpoint... 
Iteration: 1151771833, states[0] = -94.982781, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.295567
     * GNaL_b in INaL: 0.005570
     * Gto_b in Ito: 0.080653
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029661
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.153858
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 73.740349
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045916
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1151771833
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.982781 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_667_1_r153821997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.295567
     * GNaL_b in INaL: 0.005570
     * Gto_b in Ito: 0.080653
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029661
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.153858
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 73.740349
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045916
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1151771833
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.982781 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1180334652, states[0] = -95.032416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207113886, states[0] = -27.873176, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1233856196, states[0] = -95.043441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260385988, states[0] = -95.055399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287147936, states[0] = -61.709374, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1313969642, states[0] = -95.075572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332749911, states[0] = -94.956425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360260660, states[0] = -94.970015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386938973, states[0] = -95.069866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413464266, states[0] = -95.074636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433202638, states[0] = -94.877034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460439437, states[0] = -95.069922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486826168, states[0] = -95.027211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513232735, states[0] = 17.370038, states[40]= 0.006709
Saving checkpoint... 
Iteration: 1539415165, states[0] = -48.918157, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1565706261, states[0] = 27.372285, states[40]= 0.103961
Saving checkpoint... 
Iteration: 1592058788, states[0] = -95.337189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610717747, states[0] = 22.173415, states[40]= 0.013877
Saving checkpoint... 
Iteration: 1637504583, states[0] = -38.395666, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1663821291, states[0] = 21.102889, states[40]= 0.010106
Saving checkpoint... 
Iteration: 1689961114, states[0] = 2.516927, states[40]= 0.005028
Saving checkpoint... 
Iteration: 1715915932, states[0] = -95.285663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742129750, states[0] = 18.030630, states[40]= 0.007123
Saving checkpoint... 
Iteration: 1768412787, states[0] = -95.280470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794696426, states[0] = -29.784562, states[40]= 0.000466
Saving checkpoint... 
Iteration: 1821006656, states[0] = 25.548126, states[40]= 0.108535
Saving checkpoint... 
Iteration: 1840091736, states[0] = -9.191073, states[40]= 0.002448
Saving checkpoint... 
Iteration: 1866572275, states[0] = 3.340100, states[40]= 0.004510
Saving checkpoint... 
Iteration: 1892899209, states[0] = -95.064231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919178199, states[0] = -94.533510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945439261, states[0] = -95.070627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971749567, states[0] = -94.956059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997953416, states[0] = -95.072573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024163942, states[0] = -84.085871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050315629, states[0] = -95.020029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076687416, states[0] = -94.825698, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.955180
 - CaMKt in component CaMK (millimolar): 0.006730
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.384802
 - nass in component intracellular_ions (millimolar): 6.384861
 - ki in component intracellular_ions (millimolar): 145.598684
 - kss in component intracellular_ions (millimolar): 145.598665
 - cansr in component intracellular_ions (millimolar): 1.287785
 - cajsr in component intracellular_ions (millimolar): 1.249462
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003599
 - hf in component INa (dimensionless): 0.880923
 - hs in component INa (dimensionless): 0.880918
 - j in component INa (dimensionless): 0.880889
 - hsp in component INa (dimensionless): 0.727570
 - jp in component INa (dimensionless): 0.880869
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709538
 - hLp in component INaL (dimensionless): 0.448306
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.614863
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.688358
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930654
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999869
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001509
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336129
 - xs1 in component IKs (dimensionless): 0.251591
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:57:14 (28324): called boinc_finish(0)

</stderr_txt>
]]>


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