𝕏

Task 55118406

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_333-conf_865_1
Workunit 26172887
Created 28 Jun 2024, 5:22:08 UTC
Sent 28 Jun 2024, 14:49:18 UTC
Report deadline 1 Jul 2024, 14:49:18 UTC
Received 1 Jul 2024, 9:10:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 42 min 42 sec
CPU time 37 min 49 sec
Validate state Valid
Credit 43.58
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.66 MB
Peak swap size 391.88 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_333-conf_865.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_333-conf_865_1_r1409582235_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_333-conf_865_1_r1409582235_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.994599
     * GNaL_b in INaL: 0.006654
     * Gto_b in Ito: 0.072855
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031778
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.175545
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 68.678241
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045270
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9627367, states[0] = -87.753649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17277718, states[0] = -87.319935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25983149, states[0] = -87.812093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35462185, states[0] = -87.751264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46023933, states[0] = 14.481687, states[40]= 0.008980
Saving checkpoint... 
Iteration: 55858586, states[0] = 13.006793, states[40]= 0.008531
Saving checkpoint... 
Iteration: 64244901, states[0] = -50.491266, states[40]= 0.000034
Saving checkpoint... 
Iteration: 72342559, states[0] = 21.035615, states[40]= 0.017488
Saving checkpoint... 
Iteration: 81752994, states[0] = -66.259270, states[40]= 0.000003
Saving checkpoint... 
Iteration: 91306635, states[0] = -87.813139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102450193, states[0] = -87.738179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111885282, states[0] = -19.993041, states[40]= 0.001253
Saving checkpoint... 
Iteration: 121639570, states[0] = -87.821567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130335381, states[0] = 21.673700, states[40]= 0.020671
Saving checkpoint... 
Iteration: 140920530, states[0] = -78.839912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150255277, states[0] = -82.420169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158739934, states[0] = -57.513898, states[40]= 0.000012
Saving checkpoint... 
Iteration: 169088333, states[0] = -84.245849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180433253, states[0] = -87.651356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189065851, states[0] = -50.842636, states[40]= 0.000032
Saving checkpoint... 
Iteration: 198838144, states[0] = 16.697363, states[40]= 0.010043
Saving checkpoint... 
Iteration: 209182613, states[0] = 8.813221, states[40]= 0.007657
Saving checkpoint... 
Iteration: 217408726, states[0] = -71.188677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226231414, states[0] = -54.779243, states[40]= 0.000018
Saving checkpoint... 
Iteration: 237163477, states[0] = 18.979294, states[40]= 0.012288
Saving checkpoint... 
Iteration: 247727514, states[0] = -52.131413, states[40]= 0.000027
Saving checkpoint... 
Iteration: 259650155, states[0] = 24.600302, states[40]= 0.051975
Saving checkpoint... 
Iteration: 270877258, states[0] = -31.230371, states[40]= 0.000444
Saving checkpoint... 
Iteration: 280130121, states[0] = -87.838880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289589168, states[0] = -87.654918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299570400, states[0] = -77.209437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311839067, states[0] = 8.772910, states[40]= 0.007650
Saving checkpoint... 
Iteration: 321653781, states[0] = 19.620486, states[40]= 0.013410
Saving checkpoint... 
Iteration: 330431888, states[0] = -87.757783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339868446, states[0] = -28.532871, states[40]= 0.000582
Saving checkpoint... 
Iteration: 348991879, states[0] = 15.474972, states[40]= 0.009394
Saving checkpoint... 
Iteration: 359195809, states[0] = -22.787036, states[40]= 0.000974
Saving checkpoint... 
Iteration: 368604483, states[0] = -87.791244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379059341, states[0] = -71.404912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388308744, states[0] = 22.067977, states[40]= 0.023190
Saving checkpoint... 
Iteration: 397645233, states[0] = 20.097538, states[40]= 0.014495
Saving checkpoint... 
Iteration: 407640507, states[0] = 21.895805, states[40]= 0.022035
Saving checkpoint... 
Iteration: 417772555, states[0] = -87.810372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424481073, states[0] = 17.360062, states[40]= 0.010512
Saving checkpoint... 
Iteration: 433820792, states[0] = 12.943149, states[40]= 0.008529
Saving checkpoint... 
Iteration: 443497396, states[0] = 5.060545, states[40]= 0.007018
Saving checkpoint... 
Iteration: 454768307, states[0] = -87.808735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463272994, states[0] = -87.824330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472466890, states[0] = 22.117475, states[40]= 0.023540
Saving checkpoint... 
Iteration: 482249465, states[0] = -87.755385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491711760, states[0] = -65.986260, states[40]= 0.000003
Saving checkpoint... 
Iteration: 501735481, states[0] = -87.671116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511582396, states[0] = -87.764798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521152484, states[0] = 8.025011, states[40]= 0.007519
Saving checkpoint... 
Iteration: 530075635, states[0] = -87.745766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539456323, states[0] = 24.090947, states[40]= 0.044786
Saving checkpoint... 
Iteration: 549500327, states[0] = -8.969209, states[40]= 0.003555
Saving checkpoint... 
Iteration: 559053110, states[0] = -86.591312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567484666, states[0] = 5.326529, states[40]= 0.007064
Saving checkpoint... 
Iteration: 574462543, states[0] = 19.255875, states[40]= 0.012732
Saving checkpoint... 
Iteration: 583139530, states[0] = 12.724186, states[40]= 0.008471
Saving checkpoint... 
Iteration: 593750514, states[0] = -87.796980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604179576, states[0] = -34.489336, states[40]= 0.000308
Saving checkpoint... 
Iteration: 613493757, states[0] = -8.744511, states[40]= 0.003621
Saving checkpoint... 
Iteration: 623279053, states[0] = 25.660347, states[40]= 0.066766
Saving checkpoint... 
Iteration: 631678318, states[0] = -36.583132, states[40]= 0.000239
Saving checkpoint... 
Iteration: 639681343, states[0] = -41.979748, states[40]= 0.000117
Saving checkpoint... 
Iteration: 648863215, states[0] = -66.881964, states[40]= 0.000003
Saving checkpoint... 
Iteration: 658507657, states[0] = -34.742812, states[40]= 0.000299
Saving checkpoint... 
Iteration: 669160675, states[0] = -16.853585, states[40]= 0.001693
Saving checkpoint... 
Iteration: 680451645, states[0] = 19.409319, states[40]= 0.013003
Saving checkpoint... 
Iteration: 690349522, states[0] = -51.547114, states[40]= 0.000029
Saving checkpoint... 
Iteration: 700382104, states[0] = -87.667911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710345303, states[0] = -48.264785, states[40]= 0.000047
Saving checkpoint... 
Iteration: 718630375, states[0] = 9.738106, states[40]= 0.007825
Saving checkpoint... 
Iteration: 727881005, states[0] = -87.691857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737652861, states[0] = -15.469784, states[40]= 0.001941
Saving checkpoint... 
Iteration: 746134418, states[0] = 4.550097, states[40]= 0.006930
Saving checkpoint... 
Iteration: 755895266, states[0] = -87.778393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766643686, states[0] = -6.913711, states[40]= 0.004166
Saving checkpoint... 
Iteration: 777390251, states[0] = -87.768500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788547230, states[0] = -87.733764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797806490, states[0] = -5.990112, states[40]= 0.004443
Saving checkpoint... 
Iteration: 806579662, states[0] = -87.843751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816831915, states[0] = -44.293477, states[40]= 0.000084
Saving checkpoint... 
Iteration: 824440447, states[0] = 17.707601, states[40]= 0.010804
Saving checkpoint... 
Iteration: 832585637, states[0] = 40.292936, states[40]= 0.068164
Saving checkpoint... 
Iteration: 841811880, states[0] = -19.444004, states[40]= 0.001319
Saving checkpoint... 
Iteration: 851571389, states[0] = -87.834253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863559565, states[0] = -87.804833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873672315, states[0] = -63.835935, states[40]= 0.000004
Saving checkpoint... 
Iteration: 882286084, states[0] = 5.675134, states[40]= 0.007123
Saving checkpoint... 
Iteration: 892618670, states[0] = 5.445949, states[40]= 0.007084
Saving checkpoint... 
Iteration: 901348141, states[0] = -83.956559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910116942, states[0] = 5.428260, states[40]= 0.007081
Saving checkpoint... 
Iteration: 917614826, states[0] = 6.509204, states[40]= 0.007263
Saving checkpoint... 
Iteration: 927704138, states[0] = -87.751926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938819450, states[0] = -43.913092, states[40]= 0.000089
Saving checkpoint... 
Iteration: 949190462, states[0] = -87.665954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956981148, states[0] = -39.434710, states[40]= 0.000165
Saving checkpoint... 
Iteration: 965902416, states[0] = -87.856211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974396305, states[0] = -87.843820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984042223, states[0] = -87.788372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993172183, states[0] = -83.844894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003223357, states[0] = -87.835310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012745807, states[0] = 22.299882, states[40]= 0.024905
Saving checkpoint... 
Iteration: 1022566856, states[0] = 39.174943, states[40]= 0.074400
Saving checkpoint... 
Iteration: 1031093907, states[0] = 13.255904, states[40]= 0.008614
Saving checkpoint... 
Iteration: 1040378289, states[0] = -87.813622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051119650, states[0] = -12.829491, states[40]= 0.002513
Saving checkpoint... 
Iteration: 1059923063, states[0] = 14.075778, states[40]= 0.008862
Saving checkpoint... 
Iteration: 1068335577, states[0] = -86.614772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077998864, states[0] = -85.411782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088065405, states[0] = 26.123396, states[40]= 0.072623
Saving checkpoint... 
Iteration: 1096001259, states[0] = -87.087544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105382640, states[0] = -87.842448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115569329, states[0] = 22.074405, states[40]= 0.023239
Saving checkpoint... 
Iteration: 1125100949, states[0] = 0.627814, states[40]= 0.006180
Saving checkpoint... 
Iteration: 1133673466, states[0] = -87.688046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142160916, states[0] = -86.382539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152994028, states[0] = -86.696854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162171133, states[0] = -87.694127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171695580, states[0] = -87.805120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180714455, states[0] = -87.856524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190616192, states[0] = -27.818715, states[40]= 0.000623
Saving checkpoint... 
Iteration: 1199867879, states[0] = -87.828768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207662448, states[0] = -87.611952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216877397, states[0] = -87.856238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225886147, states[0] = 25.098249, states[40]= 0.059078
Saving checkpoint... 
Iteration: 1235145763, states[0] = -81.008531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244666368, states[0] = -87.722789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253974240, states[0] = -75.911608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263587175, states[0] = 0.556505, states[40]= 0.006164
Saving checkpoint... 
Iteration: 1272891330, states[0] = 19.949531, states[40]= 0.014128
Saving checkpoint... 
Iteration: 1280902876, states[0] = 12.855856, states[40]= 0.008506
Saving checkpoint... 
Iteration: 1289286990, states[0] = -47.662053, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1296932067, states[0] = -18.062053, states[40]= 0.001505
Saving checkpoint... 
Iteration: 1304963241, states[0] = -65.084500, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1316109636, states[0] = -36.256176, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1325940178, states[0] = -33.718647, states[40]= 0.000337
Saving checkpoint... 
Iteration: 1334600709, states[0] = -26.276430, states[40]= 0.000717
Saving checkpoint... 
Iteration: 1344563978, states[0] = 12.333003, states[40]= 0.008372
Saving checkpoint... 
Iteration: 1352186270, states[0] = -87.829379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360321674, states[0] = -87.723955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370070704, states[0] = 5.618497, states[40]= 0.007113
Saving checkpoint... 
Iteration: 1380496261, states[0] = -87.766768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390325087, states[0] = -87.753677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401446151, states[0] = -53.163925, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1411199919, states[0] = 25.964815, states[40]= 0.070667
Saving checkpoint... 
Iteration: 1422087195, states[0] = -19.465246, states[40]= 0.001316
Saving checkpoint... 
Iteration: 1431257584, states[0] = -26.100822, states[40]= 0.000728
Saving checkpoint... 
Iteration: 1440278297, states[0] = -57.301564, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1449244574, states[0] = -10.167027, states[40]= 0.003211
Saving checkpoint... 
Iteration: 1457460220, states[0] = -84.895031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467404597, states[0] = -4.107006, states[40]= 0.004992
Saving checkpoint... 
Iteration: 1477353019, states[0] = 40.372665, states[40]= 0.009042
Saving checkpoint... 
Iteration: 1489036043, states[0] = 20.117756, states[40]= 0.014546
Saving checkpoint... 
Iteration: 1499947332, states[0] = -71.570734, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.733561
 - CaMKt in component CaMK (millimolar): 0.036724
 - cass in component intracellular_ions (millimolar): 0.000114
 - nai in component intracellular_ions (millimolar): 7.027770
 - nass in component intracellular_ions (millimolar): 7.027914
 - ki in component intracellular_ions (millimolar): 144.908289
 - kss in component intracellular_ions (millimolar): 144.908257
 - cansr in component intracellular_ions (millimolar): 1.553292
 - cajsr in component intracellular_ions (millimolar): 1.151113
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.007451
 - hf in component INa (dimensionless): 0.693096
 - hs in component INa (dimensionless): 0.692892
 - j in component INa (dimensionless): 0.683471
 - hsp in component INa (dimensionless): 0.448247
 - jp in component INa (dimensionless): 0.658469
 - mL in component INaL (dimensionless): 0.000193
 - hL in component INaL (dimensionless): 0.298799
 - hLp in component INaL (dimensionless): 0.139786
 - a in component Ito (dimensionless): 0.001011
 - iF in component Ito (dimensionless): 0.999542
 - iS in component Ito (dimensionless): 0.177134
 - ap in component Ito (dimensionless): 0.000515
 - iFp in component Ito (dimensionless): 0.999542
 - iSp in component Ito (dimensionless): 0.214072
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.798992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.964902
 - jca in component ICaL (dimensionless): 0.948084
 - ffp in component ICaL (dimensionless): 0.999873
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.008847
 - xrf in component IKr (dimensionless): 0.028976
 - xrs in component IKr (dimensionless): 0.803050
 - xs1 in component IKs (dimensionless): 0.460687
 - xs2 in component IKs (dimensionless): 0.001125
 - xk1 in component IK1 (dimensionless): 0.996802
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:10:21 (81094): called boinc_finish(0)

</stderr_txt>
]]>


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