𝕏

Task 55116571

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_2000-conf_663_0
Workunit 26171975
Created 28 Jun 2024, 5:21:16 UTC
Sent 28 Jun 2024, 14:39:39 UTC
Report deadline 1 Jul 2024, 14:39:39 UTC
Received 29 Jun 2024, 2:22:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 44 sec
CPU time 1 hours 29 min 57 sec
Validate state Valid
Credit 43.68
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_2000-conf_663.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_2000-conf_663_0_r1738376852_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_2000-conf_663_0_r1738376852_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.103358
     * GNaL_b in INaL: 0.006946
     * Gto_b in Ito: 0.072367
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030071
     * GKs_b in IKs: 0.001980
     * GK1_b in IK1: 0.174887
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 75.186330
     * GKb_b in IKb: 0.003907
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027151
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8229073, states[0] = -93.916259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16840373, states[0] = -94.243192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25338844, states[0] = -94.048590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33071865, states[0] = 16.268511, states[40]= 0.001234
Saving checkpoint... 
Iteration: 41280195, states[0] = -93.880498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49182336, states[0] = -56.245518, states[40]= 0.000086
Saving checkpoint... 
Iteration: 57511630, states[0] = -94.166138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65102576, states[0] = 2.884767, states[40]= 0.003431
Saving checkpoint... 
Iteration: 73598654, states[0] = -94.182571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82681691, states[0] = -94.187967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91409386, states[0] = -94.105810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99778886, states[0] = -94.187552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108400686, states[0] = -94.097137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116635381, states[0] = -94.184342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124193636, states[0] = -65.997982, states[40]= 0.000018
Saving checkpoint... 
Iteration: 132829690, states[0] = -94.185519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141270994, states[0] = -93.836688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148883407, states[0] = -94.183395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157012534, states[0] = 32.665372, states[40]= 0.023713
Saving checkpoint... 
Iteration: 164754809, states[0] = -94.186756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172950059, states[0] = -94.180351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181341618, states[0] = -94.018073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188746653, states[0] = -94.186636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197351161, states[0] = -94.033922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205654500, states[0] = -94.184627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213269233, states[0] = -93.829722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221913455, states[0] = -94.181629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230790664, states[0] = -94.185764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239582851, states[0] = -94.177454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247547876, states[0] = -94.170989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255441317, states[0] = -94.128184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263509867, states[0] = -94.160557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271023311, states[0] = 32.174044, states[40]= 0.000637
Saving checkpoint... 
Iteration: 279409582, states[0] = -94.103848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287332342, states[0] = -94.000414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294953135, states[0] = -94.179539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301484941, states[0] = -94.151039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309056993, states[0] = 21.958881, states[40]= 0.000520
Saving checkpoint... 
Iteration: 317463818, states[0] = -94.141020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326031609, states[0] = 30.310490, states[40]= 0.000152
Saving checkpoint... 
Iteration: 333462687, states[0] = -94.140351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341591130, states[0] = -94.178143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350146358, states[0] = -28.215850, states[40]= 0.002389
Saving checkpoint... 
Iteration: 358032644, states[0] = 30.028728, states[40]= 0.000150
Saving checkpoint... 
Iteration: 365636595, states[0] = -94.182692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374377671, states[0] = -94.070066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382410726, states[0] = -94.104372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391013770, states[0] = 32.786667, states[40]= 0.015445
Saving checkpoint... 
Iteration: 398813541, states[0] = -94.184396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406681977, states[0] = -94.184830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415605648, states[0] = -94.179597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424012352, states[0] = 32.644667, states[40]= 0.025256
Saving checkpoint... 
Iteration: 434318923, states[0] = -93.971946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443212217, states[0] = -89.602117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453044420, states[0] = 26.368988, states[40]= 0.000252
Saving checkpoint... 
Iteration: 461060207, states[0] = 20.787491, states[40]= 0.000622
Saving checkpoint... 
Iteration: 468640581, states[0] = -94.182496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477703697, states[0] = -94.185019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485937421, states[0] = -94.179340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493961953, states[0] = -94.178213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502711997, states[0] = -94.185020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511471621, states[0] = -94.144029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519943053, states[0] = -94.178934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528888062, states[0] = -94.181216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536510035, states[0] = -94.159331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544211836, states[0] = -89.235000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553116415, states[0] = -5.473943, states[40]= 0.003269
Saving checkpoint... 
Iteration: 562058564, states[0] = 21.388502, states[40]= 0.000568
Saving checkpoint... 
Iteration: 569886743, states[0] = -94.181078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577686934, states[0] = -94.184180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585998695, states[0] = -94.176111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594214191, states[0] = -91.137978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602277252, states[0] = -93.855985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610433093, states[0] = -94.120943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619428326, states[0] = -94.117459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627651084, states[0] = -94.182425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635996540, states[0] = -94.175977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644115571, states[0] = -4.878363, states[40]= 0.003351
Saving checkpoint... 
Iteration: 652669162, states[0] = -94.183212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660879380, states[0] = -94.180943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670120262, states[0] = -8.320706, states[40]= 0.002795
Saving checkpoint... 
Iteration: 678817532, states[0] = -94.182978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687352386, states[0] = -94.033503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695141880, states[0] = -25.013002, states[40]= 0.002373
Saving checkpoint... 
Iteration: 703479115, states[0] = -94.146621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712121993, states[0] = -9.662289, states[40]= 0.002552
Saving checkpoint... 
Iteration: 721265962, states[0] = -93.815184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729605554, states[0] = -94.178123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737395857, states[0] = -94.088641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746328498, states[0] = -93.990680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755847279, states[0] = -94.181680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763583247, states[0] = -94.175055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771080938, states[0] = 12.808852, states[40]= 0.001745
Saving checkpoint... 
Iteration: 778865657, states[0] = -94.180915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787214848, states[0] = -91.524692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795627590, states[0] = -94.179978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804100541, states[0] = 4.008504, states[40]= 0.003315
Saving checkpoint... 
Iteration: 812999664, states[0] = -94.175007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821143134, states[0] = -25.910733, states[40]= 0.002422
Saving checkpoint... 
Iteration: 828802641, states[0] = -94.182678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836378996, states[0] = -94.069503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844828831, states[0] = -94.181868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853739000, states[0] = -94.183500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862090050, states[0] = 8.950116, states[40]= 0.002481
Saving checkpoint... 
Iteration: 870216850, states[0] = -92.401696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878750531, states[0] = -94.183326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887351761, states[0] = -94.031577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895608204, states[0] = -94.177644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903497276, states[0] = -94.153138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911553151, states[0] = -94.169016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919758239, states[0] = -94.183064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927505391, states[0] = -94.155942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937478302, states[0] = -94.145162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946330405, states[0] = -93.993530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954135045, states[0] = -19.990605, states[40]= 0.001811
Saving checkpoint... 
Iteration: 962933111, states[0] = -94.177304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970974601, states[0] = -94.175416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978935486, states[0] = -94.177126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987183301, states[0] = -56.611579, states[40]= 0.000083
Saving checkpoint... 
Iteration: 994943213, states[0] = -94.176711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003286474, states[0] = -93.883895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011997272, states[0] = -94.174189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020675823, states[0] = -94.181758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029986876, states[0] = -94.174581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039317285, states[0] = -93.965430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047252996, states[0] = -93.762359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055984140, states[0] = -94.174585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063774334, states[0] = -94.182173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071087332, states[0] = 10.134787, states[40]= 0.002252
Saving checkpoint... 
Iteration: 1078892892, states[0] = -94.178458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087370880, states[0] = -94.058154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094571033, states[0] = -94.171558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102783712, states[0] = -94.181822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111082599, states[0] = 12.127939, states[40]= 0.001871
Saving checkpoint... 
Iteration: 1119206722, states[0] = -82.552612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128118762, states[0] = -7.183914, states[40]= 0.002996
Saving checkpoint... 
Iteration: 1136718498, states[0] = -94.182128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144148754, states[0] = -29.926001, states[40]= 0.002237
Saving checkpoint... 
Iteration: 1151536072, states[0] = -94.163974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159919772, states[0] = -94.176961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169717227, states[0] = -94.181964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178147181, states[0] = -28.800009, states[40]= 0.002348
Saving checkpoint... 
Iteration: 1186189256, states[0] = -61.783618, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1194794395, states[0] = -94.181168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203037207, states[0] = 28.696721, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1210592695, states[0] = -94.174300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218673530, states[0] = -94.180749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226305415, states[0] = -93.936081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234345700, states[0] = -94.020049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243806837, states[0] = -94.180636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252183786, states[0] = -57.018320, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1260543373, states[0] = -94.165231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268718936, states[0] = -94.181516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278271417, states[0] = -93.832496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284904831, states[0] = -94.177008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292438329, states[0] = -94.121353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300370453, states[0] = -94.056595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308619883, states[0] = -94.176902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317444914, states[0] = -94.125509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325607782, states[0] = -94.175593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333225497, states[0] = -93.543688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343094755, states[0] = 6.817784, states[40]= 0.002876
Saving checkpoint... 
Iteration: 1351717482, states[0] = -94.181118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359817693, states[0] = -94.179799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367553999, states[0] = -94.167066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374710920, states[0] = -94.180942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382789868, states[0] = -94.180391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391947286, states[0] = -94.174680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400170073, states[0] = -45.838244, states[40]= 0.000411
Saving checkpoint... 
Iteration: 1407800176, states[0] = -94.180039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416238437, states[0] = -93.695820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423941506, states[0] = -94.174786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432267022, states[0] = -93.815755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440591235, states[0] = -94.173032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448581228, states[0] = -94.171557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456660051, states[0] = -94.179047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465329121, states[0] = -93.988539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473466107, states[0] = -94.136799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482424951, states[0] = -94.110886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490898234, states[0] = -94.176319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498579252, states[0] = -94.171019, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.047725
 - CaMKt in component CaMK (millimolar): 0.005638
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.724503
 - nass in component intracellular_ions (millimolar): 6.724617
 - ki in component intracellular_ions (millimolar): 145.121540
 - kss in component intracellular_ions (millimolar): 145.121527
 - cansr in component intracellular_ions (millimolar): 1.811427
 - cajsr in component intracellular_ions (millimolar): 1.810385
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.003944
 - hf in component INa (dimensionless): 0.864372
 - hs in component INa (dimensionless): 0.864374
 - j in component INa (dimensionless): 0.864384
 - hsp in component INa (dimensionless): 0.697074
 - jp in component INa (dimensionless): 0.864390
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.705915
 - hLp in component INaL (dimensionless): 0.492614
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.883654
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.923719
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.969579
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004268
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.113237
 - xs1 in component IKs (dimensionless): 0.141420
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997552
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:22:28 (12594): called boinc_finish(0)

</stderr_txt>
]]>


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