𝕏

Task 55115283

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_2000-conf_161_1
Workunit 26171331
Created 28 Jun 2024, 5:20:39 UTC
Sent 28 Jun 2024, 14:27:05 UTC
Report deadline 1 Jul 2024, 14:27:05 UTC
Received 28 Jun 2024, 21:52:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 17 min 51 sec
CPU time 2 hours 12 min 58 sec
Validate state Valid
Credit 42.73
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.75 MB
Peak swap size 2.35 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_2000-conf_161.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_2000-conf_161_1_r1429051117_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_2000-conf_161_1_r1429051117_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.981014
     * GNaL_b in INaL: 0.005696
     * Gto_b in Ito: 0.099102
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033036
     * GKs_b in IKs: 0.002028
     * GK1_b in IK1: 0.154215
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 71.507736
     * GKb_b in IKb: 0.003688
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023333
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11121764, states[0] = -24.262714, states[40]= 0.000368
Saving checkpoint... 
Iteration: 22258360, states[0] = -83.521118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33262211, states[0] = -83.486534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44394474, states[0] = -83.843775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55507497, states[0] = -83.922658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66624613, states[0] = -83.941902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77705185, states[0] = -83.938970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88776710, states[0] = -83.932647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99875786, states[0] = -83.923845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110994960, states[0] = -83.912879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122156796, states[0] = -51.510625, states[40]= 0.000026
Saving checkpoint... 
Iteration: 133129275, states[0] = -26.817818, states[40]= 0.000287
Saving checkpoint... 
Iteration: 144338377, states[0] = -83.685451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155487023, states[0] = -83.874291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166620612, states[0] = -83.913686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177759542, states[0] = -83.918362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188759056, states[0] = -83.917967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199522841, states[0] = -83.889203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209984888, states[0] = -83.905162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220938950, states[0] = -83.908109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232064918, states[0] = 15.980146, states[40]= 0.000063
Saving checkpoint... 
Iteration: 243200831, states[0] = -82.784334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254387020, states[0] = -83.775914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265488514, states[0] = -83.872182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276611135, states[0] = -83.910093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287600955, states[0] = -83.908472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298732586, states[0] = -83.916698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309844006, states[0] = -83.912994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320941371, states[0] = -83.906929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332076523, states[0] = 10.848943, states[40]= 0.000132
Saving checkpoint... 
Iteration: 343193371, states[0] = -81.898755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354325132, states[0] = -83.645968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365470374, states[0] = -83.860439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376616502, states[0] = -83.910080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387760623, states[0] = -83.915700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398878230, states[0] = -83.910440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409988965, states[0] = -83.903037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420836499, states[0] = -83.912614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431918192, states[0] = -83.907709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442894419, states[0] = -83.909156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454026025, states[0] = 29.380787, states[40]= 0.000205
Saving checkpoint... 
Iteration: 465125104, states[0] = -22.850693, states[40]= 0.000277
Saving checkpoint... 
Iteration: 476106796, states[0] = -6.113502, states[40]= 0.000460
Saving checkpoint... 
Iteration: 487259171, states[0] = -83.380090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498359232, states[0] = -83.725972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509478255, states[0] = -83.864485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520510285, states[0] = -83.881174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531637151, states[0] = -83.911368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542744561, states[0] = -83.914935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553838500, states[0] = -83.911626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564960892, states[0] = -83.903951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576111374, states[0] = -9.979541, states[40]= 0.000409
Saving checkpoint... 
Iteration: 587226226, states[0] = -83.173448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598353957, states[0] = -83.714533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609316072, states[0] = -83.617503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620426213, states[0] = -83.822149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631496001, states[0] = -83.873620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642603359, states[0] = -83.906433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653705254, states[0] = -83.914136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664852327, states[0] = -83.910154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676016314, states[0] = 30.235299, states[40]= 0.006164
Saving checkpoint... 
Iteration: 687149397, states[0] = -44.644429, states[40]= 0.000067
Saving checkpoint... 
Iteration: 698313349, states[0] = -83.608365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709448193, states[0] = -83.841739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720568775, states[0] = -83.899207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731720211, states[0] = -83.913775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742847108, states[0] = -83.909917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754006857, states[0] = 27.442674, states[40]= 0.174204
Saving checkpoint... 
Iteration: 765009217, states[0] = 28.494015, states[40]= 0.075842
Saving checkpoint... 
Iteration: 776151616, states[0] = -46.620579, states[40]= 0.000052
Saving checkpoint... 
Iteration: 787307776, states[0] = -83.589527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798282368, states[0] = -83.491710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809407765, states[0] = -83.800232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820448849, states[0] = -83.841535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831572549, states[0] = -83.899342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842779167, states[0] = -83.912187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853918463, states[0] = -83.904880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865089872, states[0] = 4.417491, states[40]= 0.000281
Saving checkpoint... 
Iteration: 876267362, states[0] = -83.420507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887412125, states[0] = -83.804934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898539195, states[0] = -83.889732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909723496, states[0] = -83.912603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920698969, states[0] = -83.912238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931806864, states[0] = -83.910589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942954489, states[0] = -83.901873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954079175, states[0] = 9.627188, states[40]= 0.000155
Saving checkpoint... 
Iteration: 965224440, states[0] = -83.158136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976354060, states[0] = -83.712198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987415608, states[0] = -83.808279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998579989, states[0] = -83.899844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009678720, states[0] = -83.910997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020852389, states[0] = -83.907781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032000729, states[0] = 30.579645, states[40]= 0.199661
Saving checkpoint... 
Iteration: 1043147123, states[0] = -42.615018, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1054326440, states[0] = -83.644866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065472120, states[0] = -83.856905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076501063, states[0] = -83.873182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087691741, states[0] = -83.910942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098871267, states[0] = -83.906190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110026305, states[0] = 29.327987, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1121212887, states[0] = -83.062441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132375780, states[0] = -83.751984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143533668, states[0] = -83.886233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154711584, states[0] = -83.910893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165876087, states[0] = -83.905460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176870959, states[0] = -83.905689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188001642, states[0] = 33.715285, states[40]= 0.943711
Saving checkpoint... 
Iteration: 1199194457, states[0] = -82.105716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210383354, states[0] = -83.763732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221591328, states[0] = -83.900560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232671077, states[0] = -83.909158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243794742, states[0] = -83.908991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254922891, states[0] = -83.901919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266039881, states[0] = 25.633205, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1277209746, states[0] = -83.023931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288353924, states[0] = -83.709807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299506822, states[0] = -83.874419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310633523, states[0] = -83.905828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321780868, states[0] = -83.908947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332943426, states[0] = -83.900027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344109668, states[0] = -8.475945, states[40]= 0.000434
Saving checkpoint... 
Iteration: 1355266948, states[0] = -83.415098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366381795, states[0] = -83.760232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377571148, states[0] = -83.895388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388588991, states[0] = -83.899020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399744870, states[0] = -83.909230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410903738, states[0] = -83.902122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422004951, states[0] = 27.292614, states[40]= 0.339106
Saving checkpoint... 
Iteration: 1433152711, states[0] = -47.588847, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1444253970, states[0] = -83.344356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455381766, states[0] = -83.759587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466531462, states[0] = -83.883305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477704064, states[0] = -83.908634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488821212, states[0] = -83.906249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499863903, states[0] = -83.903947, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.770936
 - CaMKt in component CaMK (millimolar): 0.005314
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.396639
 - nass in component intracellular_ions (millimolar): 6.396747
 - ki in component intracellular_ions (millimolar): 145.460398
 - kss in component intracellular_ions (millimolar): 145.460382
 - cansr in component intracellular_ions (millimolar): 1.688695
 - cajsr in component intracellular_ions (millimolar): 1.687884
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.011091
 - hf in component INa (dimensionless): 0.540782
 - hs in component INa (dimensionless): 0.540789
 - j in component INa (dimensionless): 0.540822
 - hsp in component INa (dimensionless): 0.298354
 - jp in component INa (dimensionless): 0.540840
 - mL in component INaL (dimensionless): 0.000411
 - hL in component INaL (dimensionless): 0.378503
 - hLp in component INaL (dimensionless): 0.203050
 - a in component Ito (dimensionless): 0.001320
 - iF in component Ito (dimensionless): 0.999085
 - iS in component Ito (dimensionless): 0.845310
 - ap in component Ito (dimensionless): 0.000673
 - iFp in component Ito (dimensionless): 0.999085
 - iSp in component Ito (dimensionless): 0.873924
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973926
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003198
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.210818
 - xs1 in component IKs (dimensionless): 0.131049
 - xs2 in component IKs (dimensionless): 0.000305
 - xk1 in component IK1 (dimensionless): 0.996972
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
13:47:32 (67839): called boinc_finish(0)

</stderr_txt>
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