𝕏

Task 55114751

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0
Workunit 26171066
Created 28 Jun 2024, 5:20:24 UTC
Sent 28 Jun 2024, 14:18:31 UTC
Report deadline 1 Jul 2024, 14:18:31 UTC
Received 30 Jun 2024, 2:19:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230611
Run time 2 hours 9 min 36 sec
CPU time 1 hours 35 min 27 sec
Validate state Valid
Credit 45.46
Device peak FLOPS 3.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 5.34 MB
Peak disk usage 0.36 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 19190144, states[0] = -94.734015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37967887, states[0] = -95.097458, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 37967887
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.097458 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 56122750, states[0] = -31.831571, states[40]= 0.000898


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 56122750
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -31.831571 (After loading)
 - states[40]: 0.000898 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 77234486, states[0] = -94.831114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97424305, states[0] = -95.065988, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 97424305
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.065988 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 108313816, states[0] = -94.983947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125009756, states[0] = 27.185196, states[40]= 0.053239
Saving checkpoint... 
Iteration: 142936113, states[0] = -95.068051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159143368, states[0] = -51.657719, states[40]= 0.000075


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 159143368
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -51.657719 (After loading)
 - states[40]: 0.000075 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 159143368
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -51.657719 (After loading)
 - states[40]: 0.000075 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 175092941, states[0] = -4.019307, states[40]= 0.003902
Saving checkpoint... 
Iteration: 187844679, states[0] = -95.014301, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 187844679
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.014301 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 200070402, states[0] = 9.364341, states[40]= 0.004115
Saving checkpoint... 
Iteration: 212944089, states[0] = -95.069826, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 212944089
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.069826 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 212944089
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.069826 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 212944089
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.069826 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 229445396, states[0] = -95.070146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247793682, states[0] = -94.953520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264443041, states[0] = -95.069207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282046807, states[0] = 19.090638, states[40]= 0.002331
Saving checkpoint... 
Iteration: 299212357, states[0] = -94.751324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315803139, states[0] = -94.967038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332541619, states[0] = 20.961392, states[40]= 0.001988
Saving checkpoint... 
Iteration: 348562594, states[0] = 12.865562, states[40]= 0.003561


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 348562594
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.865562 (After loading)
 - states[40]: 0.003561 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 362289955, states[0] = -94.947176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374589431, states[0] = -1.417466, states[40]= 0.004297
Saving checkpoint... 
Iteration: 386184617, states[0] = -94.573034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397709009, states[0] = -94.738335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407360027, states[0] = -95.025901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419346247, states[0] = -95.014567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431437249, states[0] = -95.066556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442394087, states[0] = -95.047677, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 442394087
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.047677 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 455231963, states[0] = -94.816627, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_661_0_r55746422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.750492
     * GNaL_b in INaL: 0.006618
     * Gto_b in Ito: 0.090848
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030967
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.175626
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.285518
     * GKb_b in IKb: 0.003928
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044925
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 455231963
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.816627 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 468883967, states[0] = -95.041831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473973565, states[0] = -95.076949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479242218, states[0] = -94.845995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486682841, states[0] = -94.513296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499412467, states[0] = -95.056477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512514656, states[0] = 27.342930, states[40]= 0.010818
Saving checkpoint... 
Iteration: 525546048, states[0] = 19.369779, states[40]= 0.002278
Saving checkpoint... 
Iteration: 539171775, states[0] = -90.802049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552432648, states[0] = -95.064427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566929401, states[0] = -95.063165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580271023, states[0] = -94.912574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593554835, states[0] = 16.038820, states[40]= 0.002942
Saving checkpoint... 
Iteration: 607886187, states[0] = -95.042579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622253900, states[0] = -94.875182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636832739, states[0] = -95.000936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651178248, states[0] = -94.083236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662443797, states[0] = -95.067828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672687856, states[0] = -94.628256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683987184, states[0] = -95.079147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695325064, states[0] = -94.992607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707588750, states[0] = -0.943781, states[40]= 0.004350
Saving checkpoint... 
Iteration: 719721407, states[0] = -94.781662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730911366, states[0] = -95.055047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742648641, states[0] = -57.410647, states[40]= 0.000030
Saving checkpoint... 
Iteration: 754397757, states[0] = -95.048355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766094969, states[0] = -5.628880, states[40]= 0.003588
Saving checkpoint... 
Iteration: 777696493, states[0] = -94.685413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789422302, states[0] = -95.059492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799548438, states[0] = 18.487021, states[40]= 0.002449
Saving checkpoint... 
Iteration: 812522849, states[0] = 26.465915, states[40]= 0.001769
Saving checkpoint... 
Iteration: 825309240, states[0] = -94.973162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836143709, states[0] = -51.987972, states[40]= 0.000071
Saving checkpoint... 
Iteration: 848685845, states[0] = -94.597919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861286480, states[0] = -94.939474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873686864, states[0] = -94.614537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884319947, states[0] = -94.986069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896471739, states[0] = -95.074800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909973818, states[0] = -95.075249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922112915, states[0] = -22.188111, states[40]= 0.001264
Saving checkpoint... 
Iteration: 934212597, states[0] = -94.749604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946336838, states[0] = -95.003743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957691389, states[0] = -94.657481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969396339, states[0] = -95.046745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983259375, states[0] = -94.886392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997070029, states[0] = 9.544066, states[40]= 0.004092
Saving checkpoint... 
Iteration: 1010906100, states[0] = -95.051470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024954076, states[0] = -95.069543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038895187, states[0] = -95.045854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052842100, states[0] = -95.008277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066589221, states[0] = -1.269099, states[40]= 0.004314
Saving checkpoint... 
Iteration: 1078608402, states[0] = -17.954535, states[40]= 0.001414
Saving checkpoint... 
Iteration: 1089956458, states[0] = -95.069971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099367292, states[0] = -95.028436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108674773, states[0] = -93.006230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117716629, states[0] = -94.763455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127710918, states[0] = -94.742564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136746537, states[0] = -94.854770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146631839, states[0] = -39.794590, states[40]= 0.000389
Saving checkpoint... 
Iteration: 1157869996, states[0] = -95.030086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167935574, states[0] = -95.062993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176942975, states[0] = -95.065481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187123712, states[0] = -32.121516, states[40]= 0.000887
Saving checkpoint... 
Iteration: 1195393365, states[0] = -95.044242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208129385, states[0] = -37.435573, states[40]= 0.000518
Saving checkpoint... 
Iteration: 1220531171, states[0] = 24.388059, states[40]= 0.001491
Saving checkpoint... 
Iteration: 1229877837, states[0] = -95.034979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239524127, states[0] = 26.206375, states[40]= 0.001594
Saving checkpoint... 
Iteration: 1248765676, states[0] = -94.898981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263454154, states[0] = -95.068603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276921505, states[0] = -95.057199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287164494, states[0] = -79.256558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304305182, states[0] = -94.965828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321857631, states[0] = -95.020351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337933112, states[0] = -95.061423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351940913, states[0] = -95.064090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368295649, states[0] = -94.951934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381257154, states[0] = -94.879719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391345911, states[0] = -95.010335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403440403, states[0] = -95.063710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415054976, states[0] = 15.984409, states[40]= 0.002954
Saving checkpoint... 
Iteration: 1425416054, states[0] = -95.054311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436094934, states[0] = -5.598326, states[40]= 0.003594
Saving checkpoint... 
Iteration: 1447329358, states[0] = -94.994168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458511245, states[0] = 27.244590, states[40]= 0.032423
Saving checkpoint... 
Iteration: 1469734348, states[0] = -94.819631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481540011, states[0] = 21.524732, states[40]= 0.001894
Saving checkpoint... 
Iteration: 1492374835, states[0] = -95.031982, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.954223
 - CaMKt in component CaMK (millimolar): 0.012823
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.608888
 - nass in component intracellular_ions (millimolar): 6.608986
 - ki in component intracellular_ions (millimolar): 145.271344
 - kss in component intracellular_ions (millimolar): 145.271322
 - cansr in component intracellular_ions (millimolar): 1.666674
 - cajsr in component intracellular_ions (millimolar): 1.624306
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003599
 - hf in component INa (dimensionless): 0.880906
 - hs in component INa (dimensionless): 0.880899
 - j in component INa (dimensionless): 0.880853
 - hsp in component INa (dimensionless): 0.727524
 - jp in component INa (dimensionless): 0.880822
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.708204
 - hLp in component INaL (dimensionless): 0.444949
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.609543
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.680589
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.913925
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999824
 - jca in component ICaL (dimensionless): 0.999971
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003063
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364016
 - xs1 in component IKs (dimensionless): 0.272291
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:13:40 (5680): called boinc_finish(0)

</stderr_txt>
]]>