𝕏

Task 55114291

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_660_0
Workunit 26170837
Created 28 Jun 2024, 5:20:08 UTC
Sent 28 Jun 2024, 14:27:05 UTC
Report deadline 1 Jul 2024, 14:27:05 UTC
Received 28 Jun 2024, 23:05:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 15 min 51 sec
CPU time 2 hours 11 min 1 sec
Validate state Valid
Credit 39.17
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.49 MB
Peak swap size 2.35 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_660.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_660_0_r902366392_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_660_0_r902366392_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.937761
     * GNaL_b in INaL: 0.005368
     * Gto_b in Ito: 0.096134
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030338
     * GKs_b in IKs: 0.001841
     * GK1_b in IK1: 0.159051
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 66.689009
     * GKb_b in IKb: 0.003740
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028698
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11296264, states[0] = 8.260927, states[40]= 0.005578
Saving checkpoint... 
Iteration: 22609429, states[0] = -56.608823, states[40]= 0.000011
Saving checkpoint... 
Iteration: 33896223, states[0] = -87.213531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45157978, states[0] = -87.278542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56152052, states[0] = -87.250859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66787478, states[0] = 13.422040, states[40]= 0.005932
Saving checkpoint... 
Iteration: 77794395, states[0] = 9.771782, states[40]= 0.005713
Saving checkpoint... 
Iteration: 89104386, states[0] = -49.501892, states[40]= 0.000034
Saving checkpoint... 
Iteration: 100388483, states[0] = -86.867512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111708940, states[0] = -87.403819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123004243, states[0] = 27.731726, states[40]= 0.152070
Saving checkpoint... 
Iteration: 134319182, states[0] = -8.385763, states[40]= 0.003135
Saving checkpoint... 
Iteration: 145623279, states[0] = -75.390077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156708789, states[0] = -87.402811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168017315, states[0] = 21.342324, states[40]= 0.011938
Saving checkpoint... 
Iteration: 179253040, states[0] = 32.130268, states[40]= 0.148354
Saving checkpoint... 
Iteration: 190564909, states[0] = -4.192708, states[40]= 0.004139
Saving checkpoint... 
Iteration: 201851717, states[0] = -46.195223, states[40]= 0.000056
Saving checkpoint... 
Iteration: 213128209, states[0] = -82.090698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224439916, states[0] = -87.361856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235734719, states[0] = -87.445826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247045997, states[0] = 8.906307, states[40]= 0.005670
Saving checkpoint... 
Iteration: 258369470, states[0] = -69.483340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269677860, states[0] = -87.330948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280734591, states[0] = -87.445575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291893265, states[0] = -87.134846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303223093, states[0] = -87.427911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314359077, states[0] = -55.228513, states[40]= 0.000014
Saving checkpoint... 
Iteration: 325657742, states[0] = -87.269131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336973021, states[0] = -87.427750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348135313, states[0] = -86.349411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359463627, states[0] = -87.411454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370718827, states[0] = -87.420662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381905302, states[0] = -87.259677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393195704, states[0] = -87.375039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404493866, states[0] = -87.458033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415771809, states[0] = 20.111173, states[40]= 0.008166
Saving checkpoint... 
Iteration: 427032703, states[0] = 15.776528, states[40]= 0.006181
Saving checkpoint... 
Iteration: 438302150, states[0] = 5.251009, states[40]= 0.005467
Saving checkpoint... 
Iteration: 449577365, states[0] = -17.660127, states[40]= 0.001332
Saving checkpoint... 
Iteration: 460867312, states[0] = -66.279223, states[40]= 0.000002
Saving checkpoint... 
Iteration: 471986070, states[0] = -87.447436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483249937, states[0] = -87.465496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494438378, states[0] = -87.357782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505728764, states[0] = -87.436646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517006516, states[0] = 24.109275, states[40]= 0.104791
Saving checkpoint... 
Iteration: 528266930, states[0] = 21.429806, states[40]= 0.012521
Saving checkpoint... 
Iteration: 539594943, states[0] = -38.198500, states[40]= 0.000177
Saving checkpoint... 
Iteration: 550879693, states[0] = -83.523280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562184048, states[0] = -87.346902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573509171, states[0] = 22.826615, states[40]= 0.056424
Saving checkpoint... 
Iteration: 584787252, states[0] = 13.575969, states[40]= 0.005942
Saving checkpoint... 
Iteration: 596104648, states[0] = -49.738524, states[40]= 0.000033
Saving checkpoint... 
Iteration: 607397273, states[0] = -87.207735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618713829, states[0] = -87.411497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629872698, states[0] = -74.470672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641162803, states[0] = -87.285968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652460118, states[0] = -87.404542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663604941, states[0] = -50.096226, states[40]= 0.000031
Saving checkpoint... 
Iteration: 674915287, states[0] = -87.293807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686202206, states[0] = -87.388736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697477846, states[0] = -87.434991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708782260, states[0] = 15.980965, states[40]= 0.006211
Saving checkpoint... 
Iteration: 720137384, states[0] = -86.729393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731431291, states[0] = -87.339547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742783367, states[0] = 15.466929, states[40]= 0.006138
Saving checkpoint... 
Iteration: 754067489, states[0] = -6.641135, states[40]= 0.003564
Saving checkpoint... 
Iteration: 765354060, states[0] = -49.021928, states[40]= 0.000037
Saving checkpoint... 
Iteration: 776642614, states[0] = -87.113962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787797279, states[0] = 8.173704, states[40]= 0.005634
Saving checkpoint... 
Iteration: 799078089, states[0] = -18.513339, states[40]= 0.001231
Saving checkpoint... 
Iteration: 810357289, states[0] = -52.988713, states[40]= 0.000020
Saving checkpoint... 
Iteration: 821659839, states[0] = -87.275900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832979431, states[0] = -87.437257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844241601, states[0] = -87.454526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855475208, states[0] = -87.430641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866801861, states[0] = 5.431575, states[40]= 0.005479
Saving checkpoint... 
Iteration: 878072347, states[0] = -11.831366, states[40]= 0.002329
Saving checkpoint... 
Iteration: 889407318, states[0] = -87.266859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900713385, states[0] = -87.410333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912018777, states[0] = 20.986984, states[40]= 0.010206
Saving checkpoint... 
Iteration: 923318436, states[0] = -7.597771, states[40]= 0.003329
Saving checkpoint... 
Iteration: 934624544, states[0] = -77.287458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945825408, states[0] = -15.359858, states[40]= 0.001660
Saving checkpoint... 
Iteration: 957207149, states[0] = -87.398412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968579639, states[0] = -20.341709, states[40]= 0.001048
Saving checkpoint... 
Iteration: 979910231, states[0] = -87.277037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991299511, states[0] = 6.863598, states[40]= 0.005566
Saving checkpoint... 
Iteration: 1002638390, states[0] = -86.850039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013997414, states[0] = -87.461755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025344706, states[0] = -37.921678, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1036691776, states[0] = -87.365221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047989640, states[0] = -87.451648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059223661, states[0] = -87.427891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070523260, states[0] = 19.632506, states[40]= 0.007609
Saving checkpoint... 
Iteration: 1081854597, states[0] = -49.675236, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1093203961, states[0] = -87.391847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104423688, states[0] = -87.318271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115702922, states[0] = -87.389684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127010117, states[0] = 22.615348, states[40]= 0.045082
Saving checkpoint... 
Iteration: 1138285521, states[0] = 14.434378, states[40]= 0.006020
Saving checkpoint... 
Iteration: 1149598520, states[0] = -42.387861, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1160885426, states[0] = -86.374388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172155012, states[0] = -87.257480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183432018, states[0] = -87.340883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194760910, states[0] = 22.473914, states[40]= 0.037516
Saving checkpoint... 
Iteration: 1206082908, states[0] = -24.187363, states[40]= 0.000770
Saving checkpoint... 
Iteration: 1217404906, states[0] = -87.256981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228707531, states[0] = -87.398823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239995849, states[0] = -87.459519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251327143, states[0] = -17.397209, states[40]= 0.001365
Saving checkpoint... 
Iteration: 1262542937, states[0] = 10.604603, states[40]= 0.005754
Saving checkpoint... 
Iteration: 1273836097, states[0] = -27.917748, states[40]= 0.000568
Saving checkpoint... 
Iteration: 1285152938, states[0] = -87.248023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296427884, states[0] = -87.329717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307778108, states[0] = 17.794335, states[40]= 0.006607
Saving checkpoint... 
Iteration: 1319078568, states[0] = -19.077628, states[40]= 0.001170
Saving checkpoint... 
Iteration: 1330373774, states[0] = -76.125766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341681872, states[0] = -87.340302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352993341, states[0] = -87.456171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364322398, states[0] = -11.888270, states[40]= 0.002317
Saving checkpoint... 
Iteration: 1375560558, states[0] = -0.549865, states[40]= 0.004838
Saving checkpoint... 
Iteration: 1386885372, states[0] = -86.361325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398180874, states[0] = -87.337610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409463823, states[0] = -87.410497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420662585, states[0] = -87.284279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431863372, states[0] = -60.793661, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1443024525, states[0] = 19.186507, states[40]= 0.007250
Saving checkpoint... 
Iteration: 1454352358, states[0] = -46.961117, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1465655158, states[0] = -87.257714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476957788, states[0] = -87.399015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488262055, states[0] = 22.294787, states[40]= 0.029105
Saving checkpoint... 
Iteration: 1499563565, states[0] = -3.002943, states[40]= 0.004393
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.340056
 - CaMKt in component CaMK (millimolar): 0.021135
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 6.833683
 - nass in component intracellular_ions (millimolar): 6.833787
 - ki in component intracellular_ions (millimolar): 145.115110
 - kss in component intracellular_ions (millimolar): 145.115083
 - cansr in component intracellular_ions (millimolar): 1.459229
 - cajsr in component intracellular_ions (millimolar): 1.231405
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.007752
 - hf in component INa (dimensionless): 0.679170
 - hs in component INa (dimensionless): 0.679058
 - j in component INa (dimensionless): 0.678269
 - hsp in component INa (dimensionless): 0.432803
 - jp in component INa (dimensionless): 0.675968
 - mL in component INaL (dimensionless): 0.000209
 - hL in component INaL (dimensionless): 0.381669
 - hLp in component INaL (dimensionless): 0.177136
 - a in component Ito (dimensionless): 0.001038
 - iF in component Ito (dimensionless): 0.999510
 - iS in component Ito (dimensionless): 0.287047
 - ap in component Ito (dimensionless): 0.000529
 - iFp in component Ito (dimensionless): 0.999510
 - iSp in component Ito (dimensionless): 0.332822
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.853768
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990631
 - jca in component ICaL (dimensionless): 0.990705
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004429
 - xrf in component IKr (dimensionless): 0.001995
 - xrs in component IKr (dimensionless): 0.670532
 - xs1 in component IKs (dimensionless): 0.391930
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.996900
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:58:29 (67947): called boinc_finish(0)

</stderr_txt>
]]>


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