𝕏

Task 55113850

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760_1
Workunit 26170616
Created 28 Jun 2024, 5:19:57 UTC
Sent 28 Jun 2024, 14:13:02 UTC
Report deadline 1 Jul 2024, 14:13:02 UTC
Received 29 Jun 2024, 2:50:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 56 min 55 sec
CPU time 1 hours 51 min 24 sec
Validate state Valid
Credit 42.42
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.57 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760_1_r211004931_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760_1_r211004931_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.457360
     * GNaL_b in INaL: 0.004906
     * Gto_b in Ito: 0.093010
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032485
     * GKs_b in IKs: 0.001821
     * GK1_b in IK1: 0.163620
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 71.178403
     * GKb_b in IKb: 0.003682
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031594
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13149153, states[0] = -70.852240, states[40]= 0.000002
Saving checkpoint... 
Iteration: 26299826, states[0] = -94.773731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39769117, states[0] = -94.704159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53111867, states[0] = -27.224422, states[40]= 0.001039
Saving checkpoint... 
Iteration: 66592789, states[0] = -7.848001, states[40]= 0.003143
Saving checkpoint... 
Iteration: 79912824, states[0] = -94.856042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93296922, states[0] = -94.747608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106687580, states[0] = -94.407228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119820876, states[0] = -94.780763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133047332, states[0] = 17.926677, states[40]= 0.002589
Saving checkpoint... 
Iteration: 146261937, states[0] = -94.677747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159404283, states[0] = -94.849615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172465464, states[0] = -94.873491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185443345, states[0] = -94.866398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198390967, states[0] = -94.841824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211437877, states[0] = -94.864258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224688206, states[0] = -94.409918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238064515, states[0] = 10.631037, states[40]= 0.003967
Saving checkpoint... 
Iteration: 251379190, states[0] = -94.834020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264732154, states[0] = -94.593663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278049093, states[0] = 17.243655, states[40]= 0.002728
Saving checkpoint... 
Iteration: 291365336, states[0] = -94.823732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304674618, states[0] = -94.018072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318138781, states[0] = -54.696356, states[40]= 0.000042
Saving checkpoint... 
Iteration: 331603534, states[0] = -18.571536, states[40]= 0.001342
Saving checkpoint... 
Iteration: 345059379, states[0] = 12.967989, states[40]= 0.003569
Saving checkpoint... 
Iteration: 358548309, states[0] = 17.551617, states[40]= 0.002666
Saving checkpoint... 
Iteration: 372016732, states[0] = 26.662088, states[40]= 0.006113
Saving checkpoint... 
Iteration: 385455920, states[0] = -94.869682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398905116, states[0] = -94.848903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412422519, states[0] = -94.857181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425805277, states[0] = -94.757806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439240599, states[0] = -94.619398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452555427, states[0] = 14.667511, states[40]= 0.003244
Saving checkpoint... 
Iteration: 466023247, states[0] = 25.701525, states[40]= 0.001832
Saving checkpoint... 
Iteration: 479513253, states[0] = 26.780483, states[40]= 0.017425
Saving checkpoint... 
Iteration: 492997293, states[0] = -94.879685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506423559, states[0] = -94.857253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519871164, states[0] = -94.827231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533377043, states[0] = -94.831387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546881128, states[0] = -94.834113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560303706, states[0] = -94.754927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573818698, states[0] = -94.775588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587241658, states[0] = -94.621940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600692023, states[0] = -94.429967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614095569, states[0] = -10.419185, states[40]= 0.002570
Saving checkpoint... 
Iteration: 627577050, states[0] = 4.037343, states[40]= 0.004592
Saving checkpoint... 
Iteration: 640939663, states[0] = -94.863141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654394977, states[0] = -94.842287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667874907, states[0] = -94.829340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681345391, states[0] = -94.804795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694827546, states[0] = -94.785857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708245660, states[0] = -94.633023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721696813, states[0] = -94.452797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735114635, states[0] = -29.748023, states[40]= 0.000929
Saving checkpoint... 
Iteration: 748481618, states[0] = -94.875221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761609515, states[0] = -24.636713, states[40]= 0.001120
Saving checkpoint... 
Iteration: 774923108, states[0] = -94.855967, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760_1_r211004931_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Coppini_1000-conf_760_1_r211004931_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.457360
     * GNaL_b in INaL: 0.004906
     * Gto_b in Ito: 0.093010
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032485
     * GKs_b in IKs: 0.001821
     * GK1_b in IK1: 0.163620
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 71.178403
     * GKb_b in IKb: 0.003682
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031594
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 774923108
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.855967 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 788478950, states[0] = -94.874416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802111805, states[0] = -26.926380, states[40]= 0.001057
Saving checkpoint... 
Iteration: 815663884, states[0] = -88.190493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829277549, states[0] = -94.708579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842874923, states[0] = -94.828640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856498616, states[0] = -94.878474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870199799, states[0] = -94.465831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883832744, states[0] = -94.790957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897613051, states[0] = -28.168698, states[40]= 0.001007
Saving checkpoint... 
Iteration: 911348311, states[0] = -94.806628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925140586, states[0] = -56.650215, states[40]= 0.000031
Saving checkpoint... 
Iteration: 938891676, states[0] = -94.839187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952536417, states[0] = 21.930200, states[40]= 0.001870
Saving checkpoint... 
Iteration: 966335750, states[0] = -94.793872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980116987, states[0] = -32.091991, states[40]= 0.000790
Saving checkpoint... 
Iteration: 993866788, states[0] = -94.822001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007317751, states[0] = -94.772608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021092455, states[0] = -7.416460, states[40]= 0.003244
Saving checkpoint... 
Iteration: 1034838245, states[0] = -94.796215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048280817, states[0] = -94.714069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062054352, states[0] = 15.117784, states[40]= 0.003155
Saving checkpoint... 
Iteration: 1075654652, states[0] = -73.827114, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1089243620, states[0] = -94.625620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102951746, states[0] = -94.865444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116547614, states[0] = 17.823621, states[40]= 0.002613
Saving checkpoint... 
Iteration: 1130253625, states[0] = -94.652873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143661540, states[0] = -84.799105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156979678, states[0] = -94.873098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170420232, states[0] = -94.853091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183870314, states[0] = -94.823902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197347761, states[0] = -94.804949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210862470, states[0] = -94.817711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224207717, states[0] = -94.498675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237558667, states[0] = 13.281181, states[40]= 0.003511
Saving checkpoint... 
Iteration: 1250988795, states[0] = -94.874824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264523665, states[0] = 25.613725, states[40]= 0.001774
Saving checkpoint... 
Iteration: 1278087787, states[0] = -3.354813, states[40]= 0.004068
Saving checkpoint... 
Iteration: 1289415449, states[0] = -94.850411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301964824, states[0] = -94.868609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313988574, states[0] = -94.874520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327288708, states[0] = -94.727436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340547169, states[0] = 17.996485, states[40]= 0.002579
Saving checkpoint... 
Iteration: 1353875176, states[0] = -94.826742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367253550, states[0] = -94.651707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380755658, states[0] = -94.657057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394175034, states[0] = -94.053416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407674632, states[0] = -94.013756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421177349, states[0] = -94.212044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434704427, states[0] = -94.483847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448274566, states[0] = -94.700016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461869471, states[0] = -94.822141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475392748, states[0] = -94.837646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489049116, states[0] = 17.236346, states[40]= 0.002730
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.752012
 - CaMKt in component CaMK (millimolar): 0.012865
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.760452
 - nass in component intracellular_ions (millimolar): 6.760550
 - ki in component intracellular_ions (millimolar): 145.116349
 - kss in component intracellular_ions (millimolar): 145.116327
 - cansr in component intracellular_ions (millimolar): 1.684540
 - cajsr in component intracellular_ions (millimolar): 1.643517
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003674
 - hf in component INa (dimensionless): 0.877376
 - hs in component INa (dimensionless): 0.877369
 - j in component INa (dimensionless): 0.877318
 - hsp in component INa (dimensionless): 0.720884
 - jp in component INa (dimensionless): 0.877283
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704414
 - hLp in component INaL (dimensionless): 0.443401
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.615446
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.687035
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.919637
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999851
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003148
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.360140
 - xs1 in component IKs (dimensionless): 0.261110
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:46:03 (17779): called boinc_finish(0)

</stderr_txt>
]]>