𝕏

Task 55103994

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1
Workunit 26165693
Created 28 Jun 2024, 5:15:23 UTC
Sent 28 Jun 2024, 13:03:23 UTC
Report deadline 1 Jul 2024, 13:03:23 UTC
Received 28 Jun 2024, 23:14:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 43 min 9 sec
CPU time 35 min 56 sec
Validate state Valid
Credit 42.25
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.72 MB
Peak swap size 391.95 GB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.551448
     * GNaL_b in INaL: 0.004576
     * Gto_b in Ito: 0.071411
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033859
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.157040
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.228824
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036114
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 39101291, states[0] = -93.960564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80641888, states[0] = -93.951038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118161233, states[0] = -93.947149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156992568, states[0] = -93.913332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196363985, states[0] = -93.927185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235623569, states[0] = -93.940476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272352370, states[0] = -93.907334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316886509, states[0] = -93.913843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354026831, states[0] = -93.921713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388922084, states[0] = -93.924645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428718640, states[0] = -93.931501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471816559, states[0] = -93.914828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519475721, states[0] = -93.911900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555186938, states[0] = -68.684002, states[40]= 0.000009
Saving checkpoint... 
Iteration: 596394651, states[0] = -93.925079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630318753, states[0] = -93.681648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664563516, states[0] = -93.910243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706154620, states[0] = -93.933433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746872128, states[0] = -93.913235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785945748, states[0] = -93.941797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821888536, states[0] = -93.912790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852992759, states[0] = -93.903291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888027425, states[0] = -93.917701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928366644, states[0] = -93.944286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970198505, states[0] = -82.048008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010046661, states[0] = 25.431128, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1050188524, states[0] = -70.268149, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1083123871, states[0] = -93.938723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108123129, states[0] = -93.938581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127351455, states[0] = -93.905601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141572743, states[0] = -93.918937, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.551448
     * GNaL_b in INaL: 0.004576
     * Gto_b in Ito: 0.071411
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033859
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.157040
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.228824
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036114
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1141572743
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.918937 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1181729774, states[0] = -93.915182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231949440, states[0] = -93.910917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267407710, states[0] = -93.904709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293544606, states[0] = -93.936767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317604978, states[0] = -0.300138, states[40]= 0.003298
Saving checkpoint... 
Iteration: 1345816328, states[0] = -93.944705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372219368, states[0] = -93.906689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402872822, states[0] = -93.791571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429386243, states[0] = -93.911622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456812597, states[0] = -93.912945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488677063, states[0] = -93.930994, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.779283
 - CaMKt in component CaMK (millimolar): 0.001561
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.527298
 - nass in component intracellular_ions (millimolar): 6.527423
 - ki in component intracellular_ions (millimolar): 145.335118
 - kss in component intracellular_ions (millimolar): 145.335108
 - cansr in component intracellular_ions (millimolar): 1.828348
 - cajsr in component intracellular_ions (millimolar): 1.828101
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004053
 - hf in component INa (dimensionless): 0.859116
 - hs in component INa (dimensionless): 0.859117
 - j in component INa (dimensionless): 0.859119
 - hsp in component INa (dimensionless): 0.687670
 - jp in component INa (dimensionless): 0.859121
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698591
 - hLp in component INaL (dimensionless): 0.503130
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.997613
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999174
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998761
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005376
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002140
 - xs1 in component IKs (dimensionless): 0.023508
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:26:08 (34641): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_5000-conf_249_1_r169150162_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.551448
     * GNaL_b in INaL: 0.004576
     * Gto_b in Ito: 0.071411
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033859
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.157040
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.228824
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036114
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1488677063
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.930994 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.779283
 - CaMKt in component CaMK (millimolar): 0.001561
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.527298
 - nass in component intracellular_ions (millimolar): 6.527423
 - ki in component intracellular_ions (millimolar): 145.335118
 - kss in component intracellular_ions (millimolar): 145.335108
 - cansr in component intracellular_ions (millimolar): 1.828348
 - cajsr in component intracellular_ions (millimolar): 1.828101
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004053
 - hf in component INa (dimensionless): 0.859116
 - hs in component INa (dimensionless): 0.859117
 - j in component INa (dimensionless): 0.859119
 - hsp in component INa (dimensionless): 0.687670
 - jp in component INa (dimensionless): 0.859121
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698591
 - hLp in component INaL (dimensionless): 0.503130
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.997613
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999174
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998761
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005376
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002140
 - xs1 in component IKs (dimensionless): 0.023508
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:29:34 (41272): called boinc_finish(0)

</stderr_txt>
]]>


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