𝕏

Task 55087629

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_633_0
Workunit 26157557
Created 28 Jun 2024, 5:08:03 UTC
Sent 28 Jun 2024, 10:45:02 UTC
Report deadline 1 Jul 2024, 13:37:50 UTC
Received 28 Jun 2024, 23:06:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 10 min 20 sec
CPU time 2 hours 4 min 51 sec
Validate state Valid
Credit 48.28
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.75 MB
Peak swap size 32.57 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_633.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_633_0_r1915677363_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_633_0_r1915677363_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 99.905499
     * GNaL_b in INaL: 0.004731
     * Gto_b in Ito: 0.092224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.028295
     * GKs_b in IKs: 0.001754
     * GK1_b in IK1: 0.147379
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 68.846759
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054141
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13484437, states[0] = -94.883747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26889228, states[0] = -94.806339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40318474, states[0] = -94.723473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53826651, states[0] = -94.728601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67353736, states[0] = -94.755872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80857386, states[0] = -94.757420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94381331, states[0] = -94.775937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107841127, states[0] = -94.738718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121327986, states[0] = -94.722496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134812015, states[0] = -94.699887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148438987, states[0] = -94.805449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161966756, states[0] = -94.814967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175443694, states[0] = -94.806908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188900166, states[0] = -94.785676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202325630, states[0] = -94.718083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215809522, states[0] = -94.695027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229373508, states[0] = -94.766980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242884508, states[0] = -94.775123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256139725, states[0] = -45.114315, states[40]= 0.000198
Saving checkpoint... 
Iteration: 269470746, states[0] = -94.815367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283003528, states[0] = 34.341530, states[40]= 0.406265
Saving checkpoint... 
Iteration: 296203412, states[0] = -94.379246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309715858, states[0] = -94.441718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323140572, states[0] = -45.908807, states[40]= 0.000177
Saving checkpoint... 
Iteration: 336225207, states[0] = -94.479347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349582701, states[0] = 3.424834, states[40]= 0.004548
Saving checkpoint... 
Iteration: 363098380, states[0] = -7.531476, states[40]= 0.003171
Saving checkpoint... 
Iteration: 376450351, states[0] = -94.808312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389650779, states[0] = -55.628810, states[40]= 0.000040
Saving checkpoint... 
Iteration: 402919578, states[0] = -94.795204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416121809, states[0] = -28.838278, states[40]= 0.001154
Saving checkpoint... 
Iteration: 429386345, states[0] = -94.775600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442783180, states[0] = -94.646595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456061163, states[0] = 13.693051, states[40]= 0.003381
Saving checkpoint... 
Iteration: 469116347, states[0] = -23.955297, states[40]= 0.001294
Saving checkpoint... 
Iteration: 482544600, states[0] = 19.997732, states[40]= 0.002122
Saving checkpoint... 
Iteration: 495947381, states[0] = -94.806735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509365690, states[0] = -94.759338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522843630, states[0] = -94.738035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536262224, states[0] = -94.597307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549786429, states[0] = -94.652766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563293253, states[0] = -94.665858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576797117, states[0] = -94.672821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590303056, states[0] = -94.682991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603744585, states[0] = -94.546159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617313189, states[0] = -94.698868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630747267, states[0] = -94.554421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644179657, states[0] = -89.825061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657715839, states[0] = -94.440169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671235556, states[0] = -94.515876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684723004, states[0] = -94.469302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698250229, states[0] = -94.563112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711730007, states[0] = -94.495845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725290289, states[0] = -94.659594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738646466, states[0] = -51.496133, states[40]= 0.000077
Saving checkpoint... 
Iteration: 752101901, states[0] = -10.640840, states[40]= 0.002485
Saving checkpoint... 
Iteration: 765612763, states[0] = -20.707425, states[40]= 0.001317
Saving checkpoint... 
Iteration: 779148003, states[0] = -52.963749, states[40]= 0.000061
Saving checkpoint... 
Iteration: 792583394, states[0] = 3.028464, states[40]= 0.004550
Saving checkpoint... 
Iteration: 806083583, states[0] = 2.919100, states[40]= 0.004550
Saving checkpoint... 
Iteration: 819591397, states[0] = -2.072089, states[40]= 0.004210
Saving checkpoint... 
Iteration: 833062818, states[0] = 13.008978, states[40]= 0.003511
Saving checkpoint... 
Iteration: 846538622, states[0] = 22.071317, states[40]= 0.001765
Saving checkpoint... 
Iteration: 860031768, states[0] = 24.249997, states[40]= 0.001464
Saving checkpoint... 
Iteration: 873426984, states[0] = -94.796772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886931971, states[0] = -94.798936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900496756, states[0] = -94.819340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913990895, states[0] = -94.817955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927601661, states[0] = -10.422571, states[40]= 0.002531
Saving checkpoint... 
Iteration: 941320109, states[0] = -94.707478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955019124, states[0] = 27.045769, states[40]= 0.003178
Saving checkpoint... 
Iteration: 968758220, states[0] = -94.584798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982459472, states[0] = -94.808933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996097404, states[0] = -6.704739, states[40]= 0.003354
Saving checkpoint... 
Iteration: 1009847490, states[0] = -94.740097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023809452, states[0] = -94.691486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037450007, states[0] = -94.805457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050842956, states[0] = -94.735116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064410513, states[0] = -94.787791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078006270, states[0] = 28.074696, states[40]= 0.171341
Saving checkpoint... 
Iteration: 1091935362, states[0] = -94.799535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105698379, states[0] = -94.326939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119385286, states[0] = -94.772008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132703859, states[0] = -94.378706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146346254, states[0] = -94.738242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159880675, states[0] = -94.768536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173010074, states[0] = 27.135447, states[40]= 0.047904
Saving checkpoint... 
Iteration: 1186307118, states[0] = -94.687136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199558447, states[0] = 14.792621, states[40]= 0.003165
Saving checkpoint... 
Iteration: 1212949426, states[0] = -94.804522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226344512, states[0] = -94.736066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239639076, states[0] = -44.500371, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1252904829, states[0] = -94.783848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266309203, states[0] = -94.690091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279855790, states[0] = -94.747213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293375085, states[0] = -94.763761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307041559, states[0] = 21.068425, states[40]= 0.001932
Saving checkpoint... 
Iteration: 1320769423, states[0] = -94.612126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334433713, states[0] = -94.797836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348062652, states[0] = 13.078998, states[40]= 0.003498
Saving checkpoint... 
Iteration: 1361785547, states[0] = -94.647612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375526320, states[0] = 25.722084, states[40]= 0.001419
Saving checkpoint... 
Iteration: 1389200990, states[0] = -94.355378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402966920, states[0] = -94.809536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416683546, states[0] = -92.472040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430284232, states[0] = -94.644651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443907259, states[0] = -94.784433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457565682, states[0] = 11.794424, states[40]= 0.003728
Saving checkpoint... 
Iteration: 1471339028, states[0] = -94.729015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485058461, states[0] = 14.787461, states[40]= 0.003166
Saving checkpoint... 
Iteration: 1498792332, states[0] = -94.660248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512226087, states[0] = -95.102160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525671076, states[0] = -94.822271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539076045, states[0] = -94.693674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552532618, states[0] = -94.671344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565888543, states[0] = -94.579462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579263233, states[0] = -94.260140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592488145, states[0] = -94.423226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605780787, states[0] = -94.169814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619133226, states[0] = -94.352774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632487870, states[0] = -94.330239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645777173, states[0] = -94.341658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659096341, states[0] = -94.320757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672385859, states[0] = -94.308252, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.181261
 - CaMKt in component CaMK (millimolar): 0.001130
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.350221
 - nass in component intracellular_ions (millimolar): 6.350306
 - ki in component intracellular_ions (millimolar): 145.545301
 - kss in component intracellular_ions (millimolar): 145.545290
 - cansr in component intracellular_ions (millimolar): 1.564132
 - cajsr in component intracellular_ions (millimolar): 1.564181
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003892
 - hf in component INa (dimensionless): 0.866923
 - hs in component INa (dimensionless): 0.866923
 - j in component INa (dimensionless): 0.866924
 - hsp in component INa (dimensionless): 0.701677
 - jp in component INa (dimensionless): 0.866925
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709759
 - hLp in component INaL (dimensionless): 0.516476
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.997665
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999215
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998830
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002980
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001887
 - xs1 in component IKs (dimensionless): 0.023503
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997520
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:57:15 (12259): called boinc_finish(0)

</stderr_txt>
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