𝕏

Task 55087472

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT_Block_Kr_15-conf_732_1
Workunit 26157478
Created 28 Jun 2024, 5:07:58 UTC
Sent 28 Jun 2024, 10:45:02 UTC
Report deadline 1 Jul 2024, 10:45:02 UTC
Received 29 Jun 2024, 2:50:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 56 min 17 sec
CPU time 1 hours 51 min 8 sec
Validate state Valid
Credit 41.15
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.64 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT_Block_Kr_15-conf_732.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT_Block_Kr_15-conf_732_1_r1217789800_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-TESZT_Block_Kr_15-conf_732_1_r1217789800_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 116.989383
     * GNaL_b in INaL: 0.007416
     * Gto_b in Ito: 0.099638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.028604
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.174363
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 74.481788
     * GKb_b in IKb: 0.003923
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021209
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13665325, states[0] = -71.551894, states[40]= 0.000003
Saving checkpoint... 
Iteration: 27448702, states[0] = -95.057508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41172112, states[0] = -75.457919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 54846311, states[0] = -94.975814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68578692, states[0] = 7.339052, states[40]= 0.004697
Saving checkpoint... 
Iteration: 82209256, states[0] = -94.667677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95852996, states[0] = -94.974857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109384824, states[0] = -94.998447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123057024, states[0] = 16.672506, states[40]= 0.003146
Saving checkpoint... 
Iteration: 136631230, states[0] = -31.375491, states[40]= 0.001270
Saving checkpoint... 
Iteration: 150264442, states[0] = -94.839412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163902904, states[0] = -95.007584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177345868, states[0] = -94.965420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190654590, states[0] = -52.674121, states[40]= 0.000085
Saving checkpoint... 
Iteration: 203949242, states[0] = -95.027259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217173623, states[0] = -75.722607, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230680188, states[0] = -86.961974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244117253, states[0] = -19.790812, states[40]= 0.001548
Saving checkpoint... 
Iteration: 257478762, states[0] = -95.035597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270793824, states[0] = -94.897219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284253954, states[0] = -94.812328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297592587, states[0] = -0.201049, states[40]= 0.004714
Saving checkpoint... 
Iteration: 310788874, states[0] = -94.888417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323988629, states[0] = -95.037649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337274297, states[0] = -94.860003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350364448, states[0] = -94.980939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363514732, states[0] = 27.483315, states[40]= 0.011093
Saving checkpoint... 
Iteration: 376637121, states[0] = -36.296298, states[40]= 0.000790
Saving checkpoint... 
Iteration: 389598223, states[0] = -4.021218, states[40]= 0.004131
Saving checkpoint... 
Iteration: 402596293, states[0] = -2.653042, states[40]= 0.004382
Saving checkpoint... 
Iteration: 415799115, states[0] = -94.905326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429154944, states[0] = -53.020917, states[40]= 0.000080
Saving checkpoint... 
Iteration: 442501513, states[0] = 49.131926, states[40]= 0.317657
Saving checkpoint... 
Iteration: 455918244, states[0] = -95.013757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469250765, states[0] = -94.803024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482591125, states[0] = 0.709460, states[40]= 0.004794
Saving checkpoint... 
Iteration: 495910327, states[0] = -95.009761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509493735, states[0] = -95.038002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522933911, states[0] = -95.020214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536400055, states[0] = -95.004144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549876137, states[0] = -94.988962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563361446, states[0] = -94.977608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576815134, states[0] = -94.928212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590339815, states[0] = -94.957405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603859816, states[0] = -94.976078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617341312, states[0] = -94.958834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630788703, states[0] = -94.886778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644036839, states[0] = 23.577048, states[40]= 0.001720
Saving checkpoint... 
Iteration: 657638104, states[0] = -37.142329, states[40]= 0.000717
Saving checkpoint... 
Iteration: 671112909, states[0] = -16.082099, states[40]= 0.001727
Saving checkpoint... 
Iteration: 684606614, states[0] = -10.673137, states[40]= 0.002609
Saving checkpoint... 
Iteration: 698090965, states[0] = 0.807663, states[40]= 0.004801
Saving checkpoint... 
Iteration: 711560305, states[0] = 15.443202, states[40]= 0.003428
Saving checkpoint... 
Iteration: 725131933, states[0] = -31.914701, states[40]= 0.001217
Saving checkpoint... 
Iteration: 738660059, states[0] = -58.350801, states[40]= 0.000034
Saving checkpoint... 
Iteration: 752129321, states[0] = -29.749447, states[40]= 0.001420
Saving checkpoint... 
Iteration: 765742198, states[0] = -94.777385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779224536, states[0] = -94.719640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792724243, states[0] = -94.718539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806231752, states[0] = -94.744335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819710553, states[0] = -94.666074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833105048, states[0] = -9.358922, states[40]= 0.002906
Saving checkpoint... 
Iteration: 846507934, states[0] = 27.122769, states[40]= 0.103297
Saving checkpoint... 
Iteration: 859967443, states[0] = -95.030087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873504104, states[0] = 32.290492, states[40]= 0.359858
Saving checkpoint... 
Iteration: 886999175, states[0] = -95.037573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900488985, states[0] = -95.035349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913955017, states[0] = -95.026133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927460616, states[0] = -95.027818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940877914, states[0] = -94.988601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954102783, states[0] = -7.507800, states[40]= 0.003347
Saving checkpoint... 
Iteration: 967346601, states[0] = -94.962641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981047361, states[0] = 20.154908, states[40]= 0.002378
Saving checkpoint... 
Iteration: 994462042, states[0] = -95.027969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008105567, states[0] = -9.791191, states[40]= 0.002806
Saving checkpoint... 
Iteration: 1021630609, states[0] = -30.813810, states[40]= 0.001324
Saving checkpoint... 
Iteration: 1034875723, states[0] = -94.986662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048324337, states[0] = -94.938069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061888364, states[0] = -94.995038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075376637, states[0] = -94.987145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088691219, states[0] = -94.262610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102067719, states[0] = 12.450110, states[40]= 0.004030
Saving checkpoint... 
Iteration: 1115438561, states[0] = -95.019570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128676517, states[0] = -80.639975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142001035, states[0] = 49.790325, states[40]= 0.159931
Saving checkpoint... 
Iteration: 1155560603, states[0] = 15.328186, states[40]= 0.003454
Saving checkpoint... 
Iteration: 1169108967, states[0] = -12.680630, states[40]= 0.002205
Saving checkpoint... 
Iteration: 1182619774, states[0] = -21.895693, states[40]= 0.001573
Saving checkpoint... 
Iteration: 1196280896, states[0] = -94.869806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209906902, states[0] = -95.005058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223638653, states[0] = -37.616457, states[40]= 0.000679
Saving checkpoint... 
Iteration: 1237272481, states[0] = -94.852404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251068112, states[0] = 12.284383, states[40]= 0.004060
Saving checkpoint... 
Iteration: 1264780714, states[0] = -94.869165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278472320, states[0] = -95.029699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292180468, states[0] = -87.370017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305932191, states[0] = -95.016294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319690048, states[0] = -94.108174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333460654, states[0] = -95.026154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347201076, states[0] = -94.612781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360901681, states[0] = -95.001640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374601432, states[0] = -6.437358, states[40]= 0.003601
Saving checkpoint... 
Iteration: 1388371202, states[0] = -94.981889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402101523, states[0] = -6.508411, states[40]= 0.003584
Saving checkpoint... 
Iteration: 1415744559, states[0] = -94.781623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429266653, states[0] = -94.838700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442959817, states[0] = -95.025449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456542245, states[0] = 21.871766, states[40]= 0.002029
Saving checkpoint... 
Iteration: 1470286554, states[0] = -94.879390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483911213, states[0] = -95.006126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497460249, states[0] = -95.025355, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.911087
 - CaMKt in component CaMK (millimolar): 0.013615
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.631733
 - nass in component intracellular_ions (millimolar): 6.631832
 - ki in component intracellular_ions (millimolar): 145.241275
 - kss in component intracellular_ions (millimolar): 145.241253
 - cansr in component intracellular_ions (millimolar): 1.700036
 - cajsr in component intracellular_ions (millimolar): 1.656772
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880161
 - hs in component INa (dimensionless): 0.880153
 - j in component INa (dimensionless): 0.880102
 - hsp in component INa (dimensionless): 0.726112
 - jp in component INa (dimensionless): 0.880067
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.703942
 - hLp in component INaL (dimensionless): 0.435351
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.598329
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.667714
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.906447
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999784
 - jca in component ICaL (dimensionless): 0.999964
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003222
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.380061
 - xs1 in component IKs (dimensionless): 0.286049
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:49:47 (15623): called boinc_finish(0)

</stderr_txt>
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