𝕏

Task 55087075

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932_0
Workunit 26157280
Created 28 Jun 2024, 5:07:48 UTC
Sent 28 Jun 2024, 10:45:02 UTC
Report deadline 1 Jul 2024, 10:45:02 UTC
Received 29 Jun 2024, 0:54:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 56 min 56 sec
CPU time 1 hours 51 min 39 sec
Validate state Valid
Credit 42.88
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932_0_r1772170928_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932_0_r1772170928_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.816507
     * GNaL_b in INaL: 0.005018
     * Gto_b in Ito: 0.072705
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032901
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.150357
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.922271
     * GKb_b in IKb: 0.003683
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037986
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13529845, states[0] = -94.081139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27056611, states[0] = -94.052942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40540502, states[0] = -94.038765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53987933, states[0] = -94.086368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67518090, states[0] = 33.851670, states[40]= -0.000000
Saving checkpoint... 
Iteration: 80965062, states[0] = -94.122189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94475007, states[0] = -94.103395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107956978, states[0] = -94.020148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121032729, states[0] = -94.134911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134500724, states[0] = -94.114117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148022273, states[0] = -94.085318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161224404, states[0] = -94.134195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 174660820, states[0] = -94.116473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188161341, states[0] = -94.135560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201090779, states[0] = -94.140617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214537558, states[0] = -94.119114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228020311, states[0] = -94.088112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241375724, states[0] = -94.132038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254514121, states[0] = -94.119678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267846765, states[0] = -93.805022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280942501, states[0] = -94.145631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294352861, states[0] = -94.121764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 307735728, states[0] = -49.693486, states[40]= 0.000440
Saving checkpoint... 
Iteration: 320936470, states[0] = -94.145553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334183686, states[0] = -94.124420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347563024, states[0] = 28.597964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360880426, states[0] = -94.146283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374425549, states[0] = -94.120147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387811506, states[0] = -93.658383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401370503, states[0] = -94.131321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414740824, states[0] = -94.116368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428272170, states[0] = -94.144925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441739998, states[0] = -94.122505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455264867, states[0] = -76.613127, states[40]= 0.000007
Saving checkpoint... 
Iteration: 468681737, states[0] = -94.136637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482246435, states[0] = -94.115750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495624245, states[0] = -94.127783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509168707, states[0] = -94.123269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522651646, states[0] = -5.023150, states[40]= 0.000356
Saving checkpoint... 
Iteration: 536073221, states[0] = -94.139719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549666707, states[0] = -94.115889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563103694, states[0] = -94.121979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576618675, states[0] = -94.123712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589861093, states[0] = -94.113958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603327459, states[0] = -94.144468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616782196, states[0] = -94.120283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630337563, states[0] = -93.768865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643787444, states[0] = -94.131734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657283453, states[0] = -94.113955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670780212, states[0] = -94.143119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684235539, states[0] = -94.120519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697719237, states[0] = -37.985123, states[40]= 0.001911
Saving checkpoint... 
Iteration: 711125889, states[0] = -94.136453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724580244, states[0] = -94.115278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738057569, states[0] = -94.104123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751617045, states[0] = -94.122252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764967793, states[0] = -94.111792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778484611, states[0] = -94.140455, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932_0_r1772170928_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_5000-conf_932_0_r1772170928_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.816507
     * GNaL_b in INaL: 0.005018
     * Gto_b in Ito: 0.072705
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032901
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.150357
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.922271
     * GKb_b in IKb: 0.003683
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037986
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 778484611
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.140455 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 792154644, states[0] = -94.113934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805790170, states[0] = -94.142230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819485806, states[0] = -94.115574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 833138142, states[0] = -94.127876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846957563, states[0] = -94.115703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860237157, states[0] = -50.766749, states[40]= 0.000378
Saving checkpoint... 
Iteration: 872557622, states[0] = 30.214661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884995515, states[0] = -94.110614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898002205, states[0] = -94.070809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911045790, states[0] = -94.137430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924165931, states[0] = -94.119784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937157970, states[0] = -94.112664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950102070, states[0] = 14.692545, states[40]= 0.000010
Saving checkpoint... 
Iteration: 963451218, states[0] = -94.139791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976878842, states[0] = -94.115688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990347692, states[0] = -93.802302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003944149, states[0] = -94.124179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017484271, states[0] = -94.109545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030974326, states[0] = -94.138599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044345659, states[0] = -94.115612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057703725, states[0] = -29.176690, states[40]= 0.003866
Saving checkpoint... 
Iteration: 1071065028, states[0] = -94.135433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084559705, states[0] = -94.112432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097892636, states[0] = -93.924723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111250533, states[0] = -94.128911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124568396, states[0] = -94.111994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138041119, states[0] = -94.092891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151575043, states[0] = -94.119751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165205695, states[0] = -30.132234, states[40]= 0.003705
Saving checkpoint... 
Iteration: 1178722385, states[0] = -94.129246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1192368290, states[0] = -94.108765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205892044, states[0] = -94.138953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219465375, states[0] = -94.112422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233038235, states[0] = -94.090578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246716387, states[0] = -94.116068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260307279, states[0] = -93.629770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273879087, states[0] = -94.123647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287443740, states[0] = -94.107470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301066742, states[0] = -94.133416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314725836, states[0] = -94.108818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328283405, states[0] = -94.137610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341820608, states[0] = -94.113466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355352244, states[0] = -93.814364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368761884, states[0] = -94.126354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382069514, states[0] = -94.109782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395566702, states[0] = -94.102347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409037575, states[0] = -94.118408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422656280, states[0] = -7.458973, states[40]= 0.000403
Saving checkpoint... 
Iteration: 1436056957, states[0] = -94.132589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449536325, states[0] = -94.109583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462968431, states[0] = -94.036444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476456906, states[0] = -94.119816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490001228, states[0] = 40.687776, states[40]= 1.786731
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.981313
 - CaMKt in component CaMK (millimolar): 0.001715
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.845009
 - nass in component intracellular_ions (millimolar): 7.845157
 - ki in component intracellular_ions (millimolar): 143.978484
 - kss in component intracellular_ions (millimolar): 143.978470
 - cansr in component intracellular_ions (millimolar): 1.770554
 - cajsr in component intracellular_ions (millimolar): 1.771937
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003971
 - hf in component INa (dimensionless): 0.863087
 - hs in component INa (dimensionless): 0.863087
 - j in component INa (dimensionless): 0.863088
 - hsp in component INa (dimensionless): 0.694754
 - jp in component INa (dimensionless): 0.863089
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704229
 - hLp in component INaL (dimensionless): 0.509769
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.997224
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999035
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998093
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004180
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002454
 - xs1 in component IKs (dimensionless): 0.031976
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997569
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:53:30 (14587): called boinc_finish(0)

</stderr_txt>
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