𝕏

Task 55082775

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0
Workunit 26155132
Created 28 Jun 2024, 5:05:48 UTC
Sent 28 Jun 2024, 10:23:48 UTC
Report deadline 1 Jul 2024, 10:23:48 UTC
Received 28 Jun 2024, 13:48:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 50 min 28 sec
CPU time 1 hours 50 min 28 sec
Validate state Valid
Credit 41.07
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14067064, states[0] = -94.222480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27819517, states[0] = -94.452136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42550855, states[0] = -94.159648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57205196, states[0] = -24.545196, states[40]= 0.014875
Saving checkpoint... 
Iteration: 71739596, states[0] = -94.455152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83581775, states[0] = -94.477986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97945466, states[0] = -94.372779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112755615, states[0] = -54.610417, states[40]= 0.000392
Saving checkpoint... 
Iteration: 126851933, states[0] = -94.493519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140234200, states[0] = -94.492300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154234305, states[0] = -94.482982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167885902, states[0] = -94.478420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181895292, states[0] = -94.303054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195601263, states[0] = -94.475258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208879341, states[0] = -94.268824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222825777, states[0] = -94.494784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236200127, states[0] = -94.490418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250176494, states[0] = -94.484680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264619692, states[0] = -94.478827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278717461, states[0] = -94.482854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291792083, states[0] = -94.493630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305421291, states[0] = -94.492216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318189828, states[0] = -22.710433, states[40]= 0.006395
Saving checkpoint... 
Iteration: 329940966, states[0] = -94.475135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341943508, states[0] = -94.474864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353873678, states[0] = -94.476652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365795989, states[0] = -94.478837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377628993, states[0] = -94.484286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 391643376, states[0] = -1.228280, states[40]= 0.000525
Saving checkpoint... 
Iteration: 405354733, states[0] = -94.200178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419202779, states[0] = -94.487700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432056173, states[0] = 30.440320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443618000, states[0] = -94.483550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456691089, states[0] = -94.486048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469462147, states[0] = -94.472193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483535375, states[0] = -94.447204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495544856, states[0] = -94.451427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508842059, states[0] = -94.156950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523556670, states[0] = 30.302080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535519411, states[0] = 33.887914, states[40]= -0.000000
Saving checkpoint... 
Iteration: 550107757, states[0] = -94.482099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562310617, states[0] = -94.475030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576585356, states[0] = -94.464941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590007979, states[0] = -94.430027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604442436, states[0] = -94.470428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 618637873, states[0] = -94.476361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633380632, states[0] = -94.265203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646417342, states[0] = -94.470409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659943593, states[0] = -94.469450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674467374, states[0] = -94.484693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688444636, states[0] = -94.468933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702313206, states[0] = -94.035541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715798461, states[0] = -93.958141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730840466, states[0] = -94.147460, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 730840466
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.147460 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 745583497, states[0] = 21.380861, states[40]= 0.000003
Saving checkpoint... 
Iteration: 760037459, states[0] = -94.480966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775001222, states[0] = -94.481918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790065638, states[0] = -94.479483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802685146, states[0] = -21.288739, states[40]= 0.005007
Saving checkpoint... 
Iteration: 815571294, states[0] = -94.478849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 829295641, states[0] = -94.470948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841681360, states[0] = -20.024842, states[40]= 0.003721
Saving checkpoint... 
Iteration: 855292647, states[0] = -93.902269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870205976, states[0] = -27.622003, states[40]= 0.007991
Saving checkpoint... 
Iteration: 885676509, states[0] = -94.477240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899397861, states[0] = -94.482649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914373457, states[0] = -94.482836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 926928019, states[0] = -94.465323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941291817, states[0] = -94.482599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956028192, states[0] = -94.435487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970831837, states[0] = -94.111104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984268443, states[0] = -70.426962, states[40]= 0.000037
Saving checkpoint... 
Iteration: 998931080, states[0] = -94.464011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013534610, states[0] = -94.476744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028813005, states[0] = -94.466997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042510165, states[0] = 30.512830, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1057747382, states[0] = -50.503437, states[40]= 0.000714
Saving checkpoint... 
Iteration: 1069837681, states[0] = -94.131474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084823206, states[0] = -94.073825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098518608, states[0] = -94.427775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113526246, states[0] = -94.431759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128308017, states[0] = -94.002755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141337997, states[0] = -94.464301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155812153, states[0] = -94.479118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170021737, states[0] = 34.251492, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1184595434, states[0] = -94.471712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196989962, states[0] = -94.459046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212446921, states[0] = -94.365882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226989896, states[0] = -94.458536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242061332, states[0] = 28.937502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255743539, states[0] = -47.657314, states[40]= 0.001060
Saving checkpoint... 
Iteration: 1271178469, states[0] = -94.470884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285593551, states[0] = 17.692387, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1300751343, states[0] = -53.527528, states[40]= 0.000461
Saving checkpoint... 
Iteration: 1313248952, states[0] = -94.475155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327807604, states[0] = -93.997163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341887187, states[0] = -94.475320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357062155, states[0] = -94.469939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370449123, states[0] = -94.473361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384712370, states[0] = -29.955201, states[40]= 0.007278
Saving checkpoint... 
Iteration: 1399431102, states[0] = -94.457177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414297474, states[0] = -94.460914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428674157, states[0] = -94.467716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442268994, states[0] = -94.473610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456231171, states[0] = -94.462370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468305355, states[0] = -94.459741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483476240, states[0] = -94.454519, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_3000-conf_228_0_r1664410881_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1483476240
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.454519 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1498273598, states[0] = -94.460250, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.329578
 - CaMKt in component CaMK (millimolar): 0.004511
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.976119
 - nass in component intracellular_ions (millimolar): 7.976279
 - ki in component intracellular_ions (millimolar): 143.753187
 - kss in component intracellular_ions (millimolar): 143.753169
 - cansr in component intracellular_ions (millimolar): 1.894060
 - cajsr in component intracellular_ions (millimolar): 1.896183
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003834
 - hf in component INa (dimensionless): 0.869710
 - hs in component INa (dimensionless): 0.869711
 - j in component INa (dimensionless): 0.869717
 - hsp in component INa (dimensionless): 0.706758
 - jp in component INa (dimensionless): 0.869720
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713881
 - hLp in component INaL (dimensionless): 0.516224
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.963157
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.980773
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.984937
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004547
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034375
 - xs1 in component IKs (dimensionless): 0.096355
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997483
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:07:12 (18448): called boinc_finish(0)

</stderr_txt>
]]>