𝕏

Task 55079749

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0
Workunit 26153620
Created 28 Jun 2024, 5:04:25 UTC
Sent 28 Jun 2024, 9:47:56 UTC
Report deadline 1 Jul 2024, 9:47:56 UTC
Received 28 Jun 2024, 13:45:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221580
Run time 44 min 9 sec
CPU time 40 min 12 sec
Validate state Valid
Credit 41.28
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.23 MB
Peak swap size 5.18 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 38780177, states[0] = 16.976737, states[40]= 0.006767
Saving checkpoint... 
Iteration: 78181038, states[0] = -87.182723, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 78181038
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.182723 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 117422580, states[0] = -87.161409, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 117422580
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.161409 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 154122965, states[0] = -79.353196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192025779, states[0] = 19.041302, states[40]= 0.007428
Saving checkpoint... 
Iteration: 231407222, states[0] = -87.119454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268713692, states[0] = -87.244420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307154917, states[0] = -87.112439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345189087, states[0] = -87.198836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382462467, states[0] = -87.242310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420310364, states[0] = -1.467292, states[40]= 0.004747
Saving checkpoint... 
Iteration: 459795279, states[0] = 8.879615, states[40]= 0.005866
Saving checkpoint... 
Iteration: 497450967, states[0] = -87.222191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536999357, states[0] = -87.291175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576659512, states[0] = -87.125678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615908556, states[0] = -87.122895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654486104, states[0] = -87.275740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692324632, states[0] = -16.463229, states[40]= 0.001504
Saving checkpoint... 
Iteration: 731003528, states[0] = 31.410633, states[40]= 0.143907
Saving checkpoint... 
Iteration: 770205387, states[0] = -87.229877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807376106, states[0] = -83.170371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846157117, states[0] = -87.118444, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 846157117
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.118444 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 883394207, states[0] = -87.064096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922950985, states[0] = -87.221748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959362908, states[0] = -63.522273, states[40]= 0.000003
Saving checkpoint... 
Iteration: 996766629, states[0] = 22.396876, states[40]= 0.013481
Saving checkpoint... 
Iteration: 1035933996, states[0] = -87.187012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074372964, states[0] = -79.340118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112580317, states[0] = -23.320859, states[40]= 0.000819
Saving checkpoint... 
Iteration: 1151546309, states[0] = 8.262668, states[40]= 0.005824


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1151546309
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 8.262668 (After loading)
 - states[40]: 0.005824 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1191104207, states[0] = -51.949947, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1230755794, states[0] = 26.690207, states[40]= 0.112999
Saving checkpoint... 
Iteration: 1268767173, states[0] = 22.234657, states[40]= 0.012630


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1268767173
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 22.234657 (After loading)
 - states[40]: 0.012630 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1306981117, states[0] = -87.268630, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_925_0_r107709452_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1306981117
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.268630 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1340346053, states[0] = -42.016459, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1373801863, states[0] = 4.763795, states[40]= 0.005560
Saving checkpoint... 
Iteration: 1406225020, states[0] = -87.260208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437817119, states[0] = -7.821563, states[40]= 0.003307
Saving checkpoint... 
Iteration: 1472177414, states[0] = -87.171334, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.166541
 - CaMKt in component CaMK (millimolar): 0.019959
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.881980
 - nass in component intracellular_ions (millimolar): 6.882079
 - ki in component intracellular_ions (millimolar): 145.072210
 - kss in component intracellular_ions (millimolar): 145.072186
 - cansr in component intracellular_ions (millimolar): 1.437482
 - cajsr in component intracellular_ions (millimolar): 1.216866
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007888
 - hf in component INa (dimensionless): 0.672926
 - hs in component INa (dimensionless): 0.672826
 - j in component INa (dimensionless): 0.672139
 - hsp in component INa (dimensionless): 0.425865
 - jp in component INa (dimensionless): 0.670159
 - mL in component INaL (dimensionless): 0.000215
 - hL in component INaL (dimensionless): 0.382097
 - hLp in component INaL (dimensionless): 0.178050
 - a in component Ito (dimensionless): 0.001050
 - iF in component Ito (dimensionless): 0.999495
 - iS in component Ito (dimensionless): 0.290798
 - ap in component Ito (dimensionless): 0.000535
 - iFp in component Ito (dimensionless): 0.999495
 - iSp in component Ito (dimensionless): 0.337342
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.854705
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990760
 - jca in component ICaL (dimensionless): 0.991200
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004282
 - xrf in component IKr (dimensionless): 0.001911
 - xrs in component IKr (dimensionless): 0.674255
 - xs1 in component IKs (dimensionless): 0.386442
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.996943
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:44:59 (64152): called boinc_finish(0)

</stderr_txt>
]]>