𝕏

Task 55079740

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425_1
Workunit 26153615
Created 28 Jun 2024, 5:04:25 UTC
Sent 28 Jun 2024, 9:39:16 UTC
Report deadline 1 Jul 2024, 9:39:16 UTC
Received 28 Jun 2024, 23:06:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 55 min 22 sec
CPU time 1 hours 50 min 18 sec
Validate state Valid
Credit 43.11
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 32.57 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425_1_r43833608_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425_1_r43833608_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.411489
     * GNaL_b in INaL: 0.006806
     * Gto_b in Ito: 0.083759
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029674
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.149698
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 74.954377
     * GKb_b in IKb: 0.003895
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020200
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13519950, states[0] = 20.927704, states[40]= 0.010382


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425_1_r43833608_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_500-conf_425_1_r43833608_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.411489
     * GNaL_b in INaL: 0.006806
     * Gto_b in Ito: 0.083759
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029674
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.149698
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 74.954377
     * GKb_b in IKb: 0.003895
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020200
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 13519950
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 20.927704 (After loading)
 - states[40]: 0.010382 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 26221871, states[0] = -87.379551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39601563, states[0] = -45.051123, states[40]= 0.000066
Saving checkpoint... 
Iteration: 53003557, states[0] = 31.855375, states[40]= 0.138958
Saving checkpoint... 
Iteration: 66441031, states[0] = -87.269354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79938489, states[0] = -87.257890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93184311, states[0] = -87.243934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106616081, states[0] = -61.434652, states[40]= 0.000005
Saving checkpoint... 
Iteration: 120485948, states[0] = -87.345272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134106090, states[0] = -49.070333, states[40]= 0.000036
Saving checkpoint... 
Iteration: 147649450, states[0] = -87.083228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161293023, states[0] = 11.091163, states[40]= 0.005999
Saving checkpoint... 
Iteration: 174747096, states[0] = -87.359106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188368470, states[0] = -64.429827, states[40]= 0.000003
Saving checkpoint... 
Iteration: 201960397, states[0] = -87.298766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215409475, states[0] = -87.162022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228981492, states[0] = -87.336214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242583670, states[0] = -23.446819, states[40]= 0.000825
Saving checkpoint... 
Iteration: 256115228, states[0] = -60.178119, states[40]= 0.000006
Saving checkpoint... 
Iteration: 269536326, states[0] = 14.622294, states[40]= 0.006326
Saving checkpoint... 
Iteration: 283273215, states[0] = 20.466644, states[40]= 0.008322
Saving checkpoint... 
Iteration: 297013475, states[0] = 23.332584, states[40]= 0.022882
Saving checkpoint... 
Iteration: 310731658, states[0] = -87.336340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324398752, states[0] = -87.068870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338251941, states[0] = 39.760327, states[40]= 0.090208
Saving checkpoint... 
Iteration: 352017196, states[0] = 22.416432, states[40]= 0.013119
Saving checkpoint... 
Iteration: 365765639, states[0] = 22.823213, states[40]= 0.016074
Saving checkpoint... 
Iteration: 379509758, states[0] = 24.236732, states[40]= 0.049161
Saving checkpoint... 
Iteration: 393257513, states[0] = 25.211477, states[40]= 0.080945
Saving checkpoint... 
Iteration: 407094820, states[0] = -36.052968, states[40]= 0.000236
Saving checkpoint... 
Iteration: 420829815, states[0] = -19.024863, states[40]= 0.001182
Saving checkpoint... 
Iteration: 434626614, states[0] = -76.020102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448478734, states[0] = -87.331514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462223805, states[0] = -87.323254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476075548, states[0] = -14.137968, states[40]= 0.001874
Saving checkpoint... 
Iteration: 489858994, states[0] = -52.481076, states[40]= 0.000021
Saving checkpoint... 
Iteration: 503543514, states[0] = 10.827369, states[40]= 0.005979
Saving checkpoint... 
Iteration: 517250461, states[0] = -16.866401, states[40]= 0.000024
Saving checkpoint... 
Iteration: 530997992, states[0] = -87.359574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544723538, states[0] = -87.322707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558582507, states[0] = -22.115106, states[40]= 0.000915
Saving checkpoint... 
Iteration: 572316229, states[0] = -4.482064, states[40]= 0.004107
Saving checkpoint... 
Iteration: 586025755, states[0] = 19.480298, states[40]= 0.007581
Saving checkpoint... 
Iteration: 599676384, states[0] = -87.216183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613465595, states[0] = -87.308299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627154344, states[0] = -87.134763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640804240, states[0] = 4.494045, states[40]= 0.005524
Saving checkpoint... 
Iteration: 654573336, states[0] = -11.662012, states[40]= 0.002374
Saving checkpoint... 
Iteration: 668272075, states[0] = 20.880311, states[40]= 0.008799
Saving checkpoint... 
Iteration: 681929077, states[0] = -87.223672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695693915, states[0] = -87.261983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709397181, states[0] = -87.030732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723090071, states[0] = -30.707001, states[40]= 0.000442
Saving checkpoint... 
Iteration: 736843959, states[0] = -35.083535, states[40]= 0.000267
Saving checkpoint... 
Iteration: 750551254, states[0] = 6.356458, states[40]= 0.005674
Saving checkpoint... 
Iteration: 764265973, states[0] = 22.739295, states[40]= 0.015334
Saving checkpoint... 
Iteration: 778072508, states[0] = -10.755872, states[40]= 0.002578
Saving checkpoint... 
Iteration: 791786550, states[0] = 14.509360, states[40]= 0.006313
Saving checkpoint... 
Iteration: 805389922, states[0] = -86.442660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819087052, states[0] = -27.293519, states[40]= 0.000608
Saving checkpoint... 
Iteration: 832806349, states[0] = 3.115609, states[40]= 0.005391
Saving checkpoint... 
Iteration: 846412704, states[0] = -87.173485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859905331, states[0] = -87.140897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873617320, states[0] = -62.887123, states[40]= 0.000004
Saving checkpoint... 
Iteration: 887031723, states[0] = 16.864886, states[40]= 0.006685
Saving checkpoint... 
Iteration: 900660464, states[0] = -87.165160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914276252, states[0] = 19.277623, states[40]= 0.007472
Saving checkpoint... 
Iteration: 927765805, states[0] = 22.781806, states[40]= 0.015698
Saving checkpoint... 
Iteration: 941383273, states[0] = -83.676479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954955740, states[0] = -87.288283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968309974, states[0] = 0.585486, states[40]= 0.005075
Saving checkpoint... 
Iteration: 981703695, states[0] = -87.283900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994902953, states[0] = -87.123645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008033112, states[0] = 16.206409, states[40]= 0.006558
Saving checkpoint... 
Iteration: 1021280592, states[0] = 17.388468, states[40]= 0.006804
Saving checkpoint... 
Iteration: 1034576347, states[0] = -15.045593, states[40]= 0.001716
Saving checkpoint... 
Iteration: 1047636419, states[0] = -85.470982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060910698, states[0] = -87.165894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074405222, states[0] = -87.140004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087751807, states[0] = 40.454940, states[40]= 0.083208
Saving checkpoint... 
Iteration: 1101078034, states[0] = -16.976724, states[40]= 0.001426
Saving checkpoint... 
Iteration: 1114599072, states[0] = -40.863605, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1128277753, states[0] = 18.647436, states[40]= 0.007191
Saving checkpoint... 
Iteration: 1142041015, states[0] = 12.183627, states[40]= 0.006083
Saving checkpoint... 
Iteration: 1155725017, states[0] = -87.324599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169367488, states[0] = -63.108106, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1183120736, states[0] = -67.526929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1196757617, states[0] = 25.147571, states[40]= 0.079144
Saving checkpoint... 
Iteration: 1210458047, states[0] = -87.292812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224085391, states[0] = -25.406446, states[40]= 0.000709
Saving checkpoint... 
Iteration: 1237779737, states[0] = 17.776306, states[40]= 0.006905
Saving checkpoint... 
Iteration: 1251569026, states[0] = -7.128682, states[40]= 0.003465
Saving checkpoint... 
Iteration: 1265315067, states[0] = -3.455982, states[40]= 0.004338
Saving checkpoint... 
Iteration: 1279011452, states[0] = 23.790041, states[40]= 0.034040
Saving checkpoint... 
Iteration: 1292682227, states[0] = -87.231645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306380132, states[0] = -80.653071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320003407, states[0] = 32.476285, states[40]= 0.135268
Saving checkpoint... 
Iteration: 1333706647, states[0] = -87.289787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347358925, states[0] = -52.396549, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1360978578, states[0] = -87.330306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374550301, states[0] = 6.932588, states[40]= 0.005716
Saving checkpoint... 
Iteration: 1388018186, states[0] = 22.137202, states[40]= 0.011779
Saving checkpoint... 
Iteration: 1401522189, states[0] = 20.840071, states[40]= 0.008745
Saving checkpoint... 
Iteration: 1415080311, states[0] = -19.593906, states[40]= 0.001125
Saving checkpoint... 
Iteration: 1428608783, states[0] = -52.225663, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1442194074, states[0] = -87.261579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455740352, states[0] = -87.348170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469336215, states[0] = -26.342868, states[40]= 0.000658
Saving checkpoint... 
Iteration: 1482880633, states[0] = -81.218713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496363152, states[0] = -57.560000, states[40]= 0.000009
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.236913
 - CaMKt in component CaMK (millimolar): 0.020155
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.610011
 - nass in component intracellular_ions (millimolar): 6.610113
 - ki in component intracellular_ions (millimolar): 145.344883
 - kss in component intracellular_ions (millimolar): 145.344857
 - cansr in component intracellular_ions (millimolar): 1.437019
 - cajsr in component intracellular_ions (millimolar): 1.214253
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007833
 - hf in component INa (dimensionless): 0.675466
 - hs in component INa (dimensionless): 0.675346
 - j in component INa (dimensionless): 0.674483
 - hsp in component INa (dimensionless): 0.428622
 - jp in component INa (dimensionless): 0.671905
 - mL in component INaL (dimensionless): 0.000213
 - hL in component INaL (dimensionless): 0.374241
 - hLp in component INaL (dimensionless): 0.171857
 - a in component Ito (dimensionless): 0.001045
 - iF in component Ito (dimensionless): 0.999501
 - iS in component Ito (dimensionless): 0.282507
 - ap in component Ito (dimensionless): 0.000533
 - iFp in component Ito (dimensionless): 0.999501
 - iSp in component Ito (dimensionless): 0.325914
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.847048
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.989740
 - jca in component ICaL (dimensionless): 0.990321
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004304
 - xrf in component IKr (dimensionless): 0.002412
 - xrs in component IKr (dimensionless): 0.692525
 - xs1 in component IKs (dimensionless): 0.397883
 - xs2 in component IKs (dimensionless): 0.000222
 - xk1 in component IK1 (dimensionless): 0.996926
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:57:56 (10461): called boinc_finish(0)

</stderr_txt>
]]>


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