𝕏

Task 55074849

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_21_0
Workunit 26151182
Created 28 Jun 2024, 5:02:15 UTC
Sent 28 Jun 2024, 9:03:56 UTC
Report deadline 1 Jul 2024, 11:56:44 UTC
Received 28 Jun 2024, 20:58:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213754
Run time 2 hours 36 min 44 sec
CPU time 2 hours 31 min 21 sec
Validate state Valid
Credit 48.15
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.60 MB
Peak swap size 6.24 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_21.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_21_0_r564105749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_21_0_r564105749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.569281
     * GNaL_b in INaL: 0.007316
     * Gto_b in Ito: 0.072310
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030091
     * GKs_b in IKs: 0.001878
     * GK1_b in IK1: 0.037130
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.333181
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021747
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11317999, states[0] = -90.885305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23199439, states[0] = -77.588994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34912574, states[0] = -90.866648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46822873, states[0] = -90.279422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58721542, states[0] = -82.244932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69838702, states[0] = -90.355811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81720549, states[0] = -81.830713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93551811, states[0] = 18.320788, states[40]= 0.002417
Saving checkpoint... 
Iteration: 104691912, states[0] = -73.538306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116475348, states[0] = -90.774248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128218263, states[0] = -81.148019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140277154, states[0] = -88.892348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151725317, states[0] = -82.685487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163801230, states[0] = -89.726476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173293489, states[0] = -89.519699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184189381, states[0] = -72.510229, states[40]= 0.000002
Saving checkpoint... 
Iteration: 195707832, states[0] = -78.422573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207253699, states[0] = -87.090796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219224166, states[0] = -82.414122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230751597, states[0] = -86.856601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242460801, states[0] = -90.732839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254389451, states[0] = -90.562200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266395666, states[0] = -90.584513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277185646, states[0] = -71.062690, states[40]= 0.000002
Saving checkpoint... 
Iteration: 288539710, states[0] = 22.895352, states[40]= 0.001643
Saving checkpoint... 
Iteration: 300283752, states[0] = -89.169507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312163217, states[0] = -59.872767, states[40]= 0.000017
Saving checkpoint... 
Iteration: 324179564, states[0] = -68.506927, states[40]= 0.000003
Saving checkpoint... 
Iteration: 336156157, states[0] = -55.140249, states[40]= 0.000040
Saving checkpoint... 
Iteration: 347688687, states[0] = -72.235026, states[40]= 0.000002
Saving checkpoint... 
Iteration: 359414772, states[0] = -90.641721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371295575, states[0] = -89.570716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382813145, states[0] = -89.951522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394302374, states[0] = -89.741961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406239330, states[0] = -85.204997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418320133, states[0] = -90.057193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430337583, states[0] = -90.253620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441802922, states[0] = -89.753983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453578750, states[0] = 6.726401, states[40]= 0.004328
Saving checkpoint... 
Iteration: 465285963, states[0] = -89.255433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477116844, states[0] = -22.258185, states[40]= 0.001305
Saving checkpoint... 
Iteration: 488958505, states[0] = -90.727491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500613771, states[0] = -19.492814, states[40]= 0.001344
Saving checkpoint... 
Iteration: 512509198, states[0] = 29.603335, states[40]= 0.060086
Saving checkpoint... 
Iteration: 523858118, states[0] = -90.407863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535554131, states[0] = 17.489278, states[40]= 0.002608
Saving checkpoint... 
Iteration: 547228164, states[0] = -83.228033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559338620, states[0] = -90.262310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571225106, states[0] = -82.604497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583091526, states[0] = -0.675118, states[40]= 0.004312
Saving checkpoint... 
Iteration: 595083745, states[0] = 4.059664, states[40]= 0.004471
Saving checkpoint... 
Iteration: 607002840, states[0] = 38.250495, states[40]= 0.463687
Saving checkpoint... 
Iteration: 618813186, states[0] = -89.950792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630413442, states[0] = -90.636688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642455970, states[0] = -90.723039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654425204, states[0] = -90.665893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655629101, states[0] = -32.931562, states[40]= 0.000872
Saving checkpoint... 
Iteration: 667100182, states[0] = -7.188435, states[40]= 0.003206
Saving checkpoint... 
Iteration: 679176693, states[0] = -67.190712, states[40]= 0.000004
Saving checkpoint... 
Iteration: 690690205, states[0] = -72.795864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 702364504, states[0] = -90.444370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714185923, states[0] = -71.168757, states[40]= 0.000002
Saving checkpoint... 
Iteration: 725802615, states[0] = -89.745368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737503309, states[0] = 36.329139, states[40]= 0.414304
Saving checkpoint... 
Iteration: 749481463, states[0] = -90.753248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761396656, states[0] = -90.584827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773270814, states[0] = -88.505169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785142973, states[0] = -44.734648, states[40]= 0.000206
Saving checkpoint... 
Iteration: 797130001, states[0] = -33.703641, states[40]= 0.000811
Saving checkpoint... 
Iteration: 808629820, states[0] = -33.548320, states[40]= 0.000823
Saving checkpoint... 
Iteration: 820661926, states[0] = -59.054100, states[40]= 0.000020
Saving checkpoint... 
Iteration: 832640389, states[0] = -42.556051, states[40]= 0.000279
Saving checkpoint... 
Iteration: 843964494, states[0] = -90.733703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855470536, states[0] = -90.741045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867560507, states[0] = 14.965330, states[40]= 0.003115
Saving checkpoint... 
Iteration: 879399700, states[0] = -90.594400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891343247, states[0] = -90.300099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902924840, states[0] = -90.663749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914771171, states[0] = -88.526418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926159888, states[0] = -57.720915, states[40]= 0.000026
Saving checkpoint... 
Iteration: 937603806, states[0] = -10.343338, states[40]= 0.002516
Saving checkpoint... 
Iteration: 949560840, states[0] = 14.830022, states[40]= 0.003141
Saving checkpoint... 
Iteration: 961563771, states[0] = 13.619462, states[40]= 0.003373
Saving checkpoint... 
Iteration: 973556398, states[0] = 16.605667, states[40]= 0.002786
Saving checkpoint... 
Iteration: 985048739, states[0] = 19.549956, states[40]= 0.002206
Saving checkpoint... 
Iteration: 997059683, states[0] = 15.298881, states[40]= 0.003049
Saving checkpoint... 
Iteration: 1008441846, states[0] = -90.698045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019883800, states[0] = -90.535128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031521009, states[0] = 28.624751, states[40]= 0.001995
Saving checkpoint... 
Iteration: 1043526414, states[0] = 27.302488, states[40]= 0.001258
Saving checkpoint... 
Iteration: 1055382224, states[0] = -90.528367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067308516, states[0] = -89.865282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079134318, states[0] = -37.394516, states[40]= 0.000542
Saving checkpoint... 
Iteration: 1090559907, states[0] = 15.208626, states[40]= 0.003067
Saving checkpoint... 
Iteration: 1102688660, states[0] = -72.220820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1114145555, states[0] = -46.885218, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1126216346, states[0] = -80.617880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137904247, states[0] = -90.607473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149530521, states[0] = 26.064477, states[40]= 0.001270
Saving checkpoint... 
Iteration: 1161204259, states[0] = -77.388342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172940445, states[0] = -90.694621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184373524, states[0] = -90.488456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196308174, states[0] = -89.858002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208204436, states[0] = -77.439735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220053088, states[0] = 17.892931, states[40]= 0.002527
Saving checkpoint... 
Iteration: 1231972012, states[0] = -90.740778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243921111, states[0] = -90.653126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255928024, states[0] = -90.669074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267597536, states[0] = -5.032051, states[40]= 0.003658
Saving checkpoint... 
Iteration: 1279648236, states[0] = -49.075983, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1291154952, states[0] = -54.262332, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1302635709, states[0] = -38.579303, states[40]= 0.000469
Saving checkpoint... 
Iteration: 1314632681, states[0] = -35.996197, states[40]= 0.000637
Saving checkpoint... 
Iteration: 1326595993, states[0] = -3.842613, states[40]= 0.003879
Saving checkpoint... 
Iteration: 1338397850, states[0] = -90.585823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349930128, states[0] = -90.673152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351018052, states[0] = 29.135366, states[40]= 0.003761
Saving checkpoint... 
Iteration: 1362808605, states[0] = -89.865207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374566542, states[0] = 12.442068, states[40]= 0.003585
Saving checkpoint... 
Iteration: 1385942166, states[0] = -90.696643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397513043, states[0] = 29.535745, states[40]= 0.016754
Saving checkpoint... 
Iteration: 1409473265, states[0] = -90.741262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421113538, states[0] = -19.277478, states[40]= 0.001351
Saving checkpoint... 
Iteration: 1432688722, states[0] = -72.242425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1444534713, states[0] = 24.668488, states[40]= 0.001408
Saving checkpoint... 
Iteration: 1456458952, states[0] = -90.723055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468370406, states[0] = -90.471547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480091557, states[0] = -0.693439, states[40]= 0.004310
Saving checkpoint... 
Iteration: 1492066163, states[0] = 12.605477, states[40]= 0.003556
Saving checkpoint... 
Iteration: 1503544035, states[0] = -43.427680, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1515516966, states[0] = -70.048052, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1527541059, states[0] = -89.573654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539011196, states[0] = -90.075720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550656516, states[0] = -49.033346, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1562481919, states[0] = -89.146287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573863769, states[0] = -88.853924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585548189, states[0] = -87.761688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597162687, states[0] = -87.954608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608880464, states[0] = -86.662627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620444624, states[0] = -86.542875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632334345, states[0] = -84.654107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1644148832, states[0] = -84.809906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655630881, states[0] = -86.467151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666999712, states[0] = -83.661635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1678869667, states[0] = -84.529387, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -82.346565
 - CaMKt in component CaMK (millimolar): 0.001080
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.171397
 - nass in component intracellular_ions (millimolar): 6.171478
 - ki in component intracellular_ions (millimolar): 145.733433
 - kss in component intracellular_ions (millimolar): 145.733420
 - cansr in component intracellular_ions (millimolar): 1.518471
 - cajsr in component intracellular_ions (millimolar): 1.518652
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.012791
 - hf in component INa (dimensionless): 0.482373
 - hs in component INa (dimensionless): 0.482541
 - j in component INa (dimensionless): 0.483247
 - hsp in component INa (dimensionless): 0.252144
 - jp in component INa (dimensionless): 0.483652
 - mL in component INaL (dimensionless): 0.000538
 - hL in component INaL (dimensionless): 0.339540
 - hLp in component INaL (dimensionless): 0.190414
 - a in component Ito (dimensionless): 0.001453
 - iF in component Ito (dimensionless): 0.998828
 - iS in component Ito (dimensionless): 0.993210
 - ap in component Ito (dimensionless): 0.000741
 - iFp in component Ito (dimensionless): 0.998828
 - iSp in component Ito (dimensionless): 0.995662
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998751
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002643
 - xrf in component IKr (dimensionless): 0.000018
 - xrs in component IKr (dimensionless): 0.014315
 - xs1 in component IKs (dimensionless): 0.025793
 - xs2 in component IKs (dimensionless): 0.000357
 - xk1 in component IK1 (dimensionless): 0.999231
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:59:40 (7876): called boinc_finish(0)

</stderr_txt>
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