𝕏

Task 55071830

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_10000-conf_18_1
Workunit 26149672
Created 28 Jun 2024, 5:00:57 UTC
Sent 28 Jun 2024, 8:40:56 UTC
Report deadline 1 Jul 2024, 8:40:56 UTC
Received 28 Jun 2024, 17:17:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 20 sec
CPU time 1 hours 34 min 45 sec
Validate state Valid
Credit 43.62
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_10000-conf_18.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_10000-conf_18_1_r892465768_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_ENDO_10000-conf_18_1_r892465768_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.996697
     * GNaL_b in INaL: 0.006669
     * Gto_b in Ito: 0.082649
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032114
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.180940
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 72.476772
     * GKb_b in IKb: 0.003692
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039639
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12904203, states[0] = -94.153731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25749108, states[0] = -94.102333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38673490, states[0] = -94.037463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51740639, states[0] = -94.036772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63743170, states[0] = -94.017882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77338332, states[0] = -94.021808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90474158, states[0] = -94.000286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102910992, states[0] = -94.016361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116214524, states[0] = -94.039121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129988363, states[0] = -94.010913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141654428, states[0] = -94.028221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154301761, states[0] = -94.011622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166385070, states[0] = -94.033919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178802531, states[0] = -94.012473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190531080, states[0] = -94.023044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203663750, states[0] = -94.012741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215188385, states[0] = -57.297241, states[40]= 0.000098
Saving checkpoint... 
Iteration: 228510267, states[0] = -94.013113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241177169, states[0] = -94.039613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253131067, states[0] = -94.014373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265424280, states[0] = -93.963706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278337638, states[0] = -94.013586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290644711, states[0] = -94.044479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302917294, states[0] = -94.015264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315361585, states[0] = -93.887995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326922829, states[0] = -94.023540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339261673, states[0] = -94.011334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352000792, states[0] = -94.022505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365228224, states[0] = -93.308109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377931065, states[0] = -94.015123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390856479, states[0] = -94.049021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403495099, states[0] = -94.012968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416627770, states[0] = -94.028205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429538412, states[0] = -94.010825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442951750, states[0] = -94.014962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455632692, states[0] = -94.043079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469185170, states[0] = -94.011340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481762864, states[0] = -94.025765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494695323, states[0] = -94.010552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507120442, states[0] = -94.020967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520728694, states[0] = -94.049003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533632406, states[0] = -94.012463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546595536, states[0] = -94.028707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559259118, states[0] = -94.011128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571726019, states[0] = -94.026291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583724452, states[0] = -94.012183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595946633, states[0] = -94.046582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609127901, states[0] = -94.011309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621960845, states[0] = -94.022754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634640316, states[0] = -94.010491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648405064, states[0] = -94.013009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661309770, states[0] = -94.035310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674812008, states[0] = -94.010235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687032925, states[0] = -94.021795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700067972, states[0] = 19.259784, states[40]= 0.001139
Saving checkpoint... 
Iteration: 712599040, states[0] = -94.016684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725688235, states[0] = -94.047251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738567533, states[0] = -94.012443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751944958, states[0] = -94.022838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764414741, states[0] = -94.010686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777826741, states[0] = -94.015270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790835506, states[0] = -94.048992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803179115, states[0] = -94.013650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816138523, states[0] = -94.040266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829295294, states[0] = -94.010811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842035843, states[0] = -94.021612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854902212, states[0] = -94.009957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868213386, states[0] = -94.013458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879700553, states[0] = -94.010179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892301065, states[0] = -94.018816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904619959, states[0] = -94.010261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917286113, states[0] = -94.018927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930089599, states[0] = 10.531109, states[40]= 0.002893
Saving checkpoint... 
Iteration: 942364797, states[0] = -94.018215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955657842, states[0] = -94.045006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968235664, states[0] = -94.013281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980415437, states[0] = -93.954895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993821856, states[0] = -94.011563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006340441, states[0] = -94.034153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018340787, states[0] = -94.012866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031305406, states[0] = -94.035079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043903446, states[0] = -94.011336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056371000, states[0] = -94.033307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069506894, states[0] = -94.010260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082551205, states[0] = -94.016657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095341607, states[0] = -93.851680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108429203, states[0] = -94.012495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120844892, states[0] = -94.048533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133434250, states[0] = -94.012456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146745183, states[0] = -94.025423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159224900, states[0] = -94.010614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172923315, states[0] = -94.014404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185451257, states[0] = -93.983783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197995670, states[0] = -94.014040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211379960, states[0] = -94.032930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223021101, states[0] = -94.013903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234467338, states[0] = -94.010160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246161247, states[0] = -94.039140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258320225, states[0] = -94.012706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270125807, states[0] = -10.618098, states[40]= 0.002703
Saving checkpoint... 
Iteration: 1281221837, states[0] = -94.037248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292782335, states[0] = -94.015021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304204934, states[0] = -94.010511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315718258, states[0] = -94.047952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327405682, states[0] = -94.017513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338547480, states[0] = -94.011928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348919676, states[0] = -94.011012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358917026, states[0] = -94.011008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369548257, states[0] = -94.009916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381342937, states[0] = -94.033731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392389286, states[0] = -94.017584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403302822, states[0] = -94.012628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415000601, states[0] = 39.953556, states[40]= 0.027585
Saving checkpoint... 
Iteration: 1426790816, states[0] = -94.024419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438107837, states[0] = -94.013328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450062257, states[0] = 21.348444, states[40]= 0.000844
Saving checkpoint... 
Iteration: 1462428273, states[0] = -94.017204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473672676, states[0] = -94.011465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486020817, states[0] = -94.043435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497527958, states[0] = -94.016425, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.885220
 - CaMKt in component CaMK (millimolar): 0.001061
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.659296
 - nass in component intracellular_ions (millimolar): 6.659425
 - ki in component intracellular_ions (millimolar): 145.202184
 - kss in component intracellular_ions (millimolar): 145.202176
 - cansr in component intracellular_ions (millimolar): 1.871299
 - cajsr in component intracellular_ions (millimolar): 1.871195
 - cai in component intracellular_ions (millimolar): 0.000109
 - m in component INa (dimensionless): 0.004010
 - hf in component INa (dimensionless): 0.861210
 - hs in component INa (dimensionless): 0.861210
 - j in component INa (dimensionless): 0.861210
 - hsp in component INa (dimensionless): 0.691394
 - jp in component INa (dimensionless): 0.861210
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701534
 - hLp in component INaL (dimensionless): 0.506665
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.999841
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.999844
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006022
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002165
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997592
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:20:34 (74720): called boinc_finish(0)

</stderr_txt>
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