𝕏

Task 55049375

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989_2
Workunit 25872470
Created 27 Jun 2024, 19:28:15 UTC
Sent 28 Jun 2024, 5:37:34 UTC
Report deadline 1 Jul 2024, 5:37:34 UTC
Received 29 Jun 2024, 14:38:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190916
Run time 2 hours 28 min 41 sec
CPU time 2 hours 28 min 25 sec
Validate state Valid
Credit 40.00
Device peak FLOPS 2.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.69 MB
Peak swap size 4.99 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989_2_r835866187_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989_2_r835866187_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.137717
     * GNaL_b in INaL: 0.007975
     * Gto_b in Ito: 0.070375
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032506
     * GKs_b in IKs: 0.001809
     * GK1_b in IK1: 0.153037
     * Gncx_b in INaCa_i: 0.000948
     * Pnak_b in INaK: 62.714052
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038006
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10960352, states[0] = -0.269359, states[40]= 0.001120
Saving checkpoint... 
Iteration: 21939147, states[0] = -84.026209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32861670, states[0] = -84.337927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43804357, states[0] = -84.578596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54603569, states[0] = -84.301894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65446932, states[0] = -84.091268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76467610, states[0] = -84.656900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87491665, states[0] = -33.830619, states[40]= 0.000180
Saving checkpoint... 
Iteration: 98510778, states[0] = -84.459968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109554087, states[0] = 16.894516, states[40]= 0.000041
Saving checkpoint... 
Iteration: 120599881, states[0] = -84.288956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131645882, states[0] = 31.213346, states[40]= 0.001295
Saving checkpoint... 
Iteration: 142692405, states[0] = -84.060011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153713498, states[0] = -84.654423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164743087, states[0] = -35.454563, states[40]= 0.000158
Saving checkpoint... 
Iteration: 175757367, states[0] = -84.447796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186800905, states[0] = 18.478462, states[40]= 0.000031
Saving checkpoint... 
Iteration: 197825860, states[0] = -84.126991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208836076, states[0] = -84.650092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219844809, states[0] = -10.450946, states[40]= 0.000353
Saving checkpoint... 
Iteration: 230872078, states[0] = -84.403238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241878355, states[0] = 34.080434, states[40]= 0.628437
Saving checkpoint... 
Iteration: 252905712, states[0] = -77.607951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263932353, states[0] = -84.595933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274958212, states[0] = -0.106879, states[40]= 0.000333
Saving checkpoint... 
Iteration: 285985735, states[0] = -84.347263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297029335, states[0] = 28.332148, states[40]= 0.000070
Saving checkpoint... 
Iteration: 308069212, states[0] = -84.072513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319113557, states[0] = -84.684789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330156797, states[0] = -78.625812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341199223, states[0] = -84.627884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352243108, states[0] = -35.486707, states[40]= 0.000157
Saving checkpoint... 
Iteration: 363282823, states[0] = -84.531840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374325984, states[0] = 4.731182, states[40]= 0.000221
Saving checkpoint... 
Iteration: 385350357, states[0] = -84.288132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396375230, states[0] = -56.331132, states[40]= 0.000002
Saving checkpoint... 
Iteration: 407394786, states[0] = -64.535566, states[40]= 0.000004
Saving checkpoint... 
Iteration: 418421129, states[0] = -84.566807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429446967, states[0] = 7.159481, states[40]= 0.000168
Saving checkpoint... 
Iteration: 440474476, states[0] = -84.281883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451504231, states[0] = 32.554238, states[40]= 0.464801
Saving checkpoint... 
Iteration: 462518586, states[0] = -63.096171, states[40]= 0.000005
Saving checkpoint... 
Iteration: 473529212, states[0] = -84.518935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484537629, states[0] = 24.794929, states[40]= 0.000012
Saving checkpoint... 
Iteration: 495547556, states[0] = -83.732614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506485607, states[0] = -84.342367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517418386, states[0] = -84.557970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528391127, states[0] = 32.122526, states[40]= 0.006956
Saving checkpoint... 
Iteration: 539408181, states[0] = -79.756133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550427237, states[0] = -84.579012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561443459, states[0] = 9.185873, states[40]= 0.000130
Saving checkpoint... 
Iteration: 572460227, states[0] = -84.187920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583477440, states[0] = -84.666362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594493928, states[0] = -36.333672, states[40]= 0.000147
Saving checkpoint... 
Iteration: 605508617, states[0] = -84.444810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616461247, states[0] = -84.642772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627477697, states[0] = -19.114346, states[40]= 0.000237
Saving checkpoint... 
Iteration: 638492471, states[0] = -84.374047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 649509186, states[0] = 31.657220, states[40]= 0.081643
Saving checkpoint... 
Iteration: 660524935, states[0] = -70.892860, states[40]= 0.000002
Saving checkpoint... 
Iteration: 671539517, states[0] = -84.544829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682551871, states[0] = 17.997838, states[40]= 0.000033
Saving checkpoint... 
Iteration: 693570886, states[0] = -84.078566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704591250, states[0] = -84.648673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715606485, states[0] = -23.238130, states[40]= 0.000228
Saving checkpoint... 
Iteration: 726625492, states[0] = -84.408917, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989_2_r835866187_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_750-conf_989_2_r835866187_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.137717
     * GNaL_b in INaL: 0.007975
     * Gto_b in Ito: 0.070375
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032506
     * GKs_b in IKs: 0.001809
     * GK1_b in IK1: 0.153037
     * Gncx_b in INaCa_i: 0.000948
     * Pnak_b in INaK: 62.714052
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038006
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 726625492
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.408917 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 737662569, states[0] = 24.823760, states[40]= 0.000012
Saving checkpoint... 
Iteration: 748707776, states[0] = -84.167301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759750411, states[0] = -29.527169, states[40]= 0.000088
Saving checkpoint... 
Iteration: 770789985, states[0] = -82.873375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781835828, states[0] = -84.639000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 792876816, states[0] = -44.577377, states[40]= 0.000064
Saving checkpoint... 
Iteration: 803920825, states[0] = -84.558741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814960472, states[0] = -1.807264, states[40]= 0.000363
Saving checkpoint... 
Iteration: 826022275, states[0] = -84.490077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836773862, states[0] = -69.540990, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847772168, states[0] = -84.489306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858786432, states[0] = 25.333687, states[40]= 0.000013
Saving checkpoint... 
Iteration: 869791926, states[0] = -83.231412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880795112, states[0] = -84.555489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891805886, states[0] = 15.961039, states[40]= 0.000047
Saving checkpoint... 
Iteration: 902814887, states[0] = -84.024239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913853090, states[0] = -84.660979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924917660, states[0] = -83.331996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935909112, states[0] = -84.524711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946900892, states[0] = 29.636585, states[40]= 0.000224
Saving checkpoint... 
Iteration: 957939928, states[0] = -84.023518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968981569, states[0] = -84.664309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980054248, states[0] = -83.904566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991118797, states[0] = -84.677928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002179380, states[0] = -83.906221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013242940, states[0] = -84.676591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024297991, states[0] = -83.740304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035358651, states[0] = -84.665591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046417129, states[0] = -83.256457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057485094, states[0] = -84.666894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068535732, states[0] = -81.347560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079593445, states[0] = -84.644790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090656335, states[0] = -78.160867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101718710, states[0] = -84.644752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112777984, states[0] = -74.586029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123836420, states[0] = -84.633475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134895891, states[0] = -65.842656, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1145957751, states[0] = -84.627234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157016618, states[0] = -60.759094, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1168074103, states[0] = -84.612061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179130810, states[0] = -48.815171, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1190189724, states[0] = -84.593855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201248696, states[0] = -41.286693, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1212304074, states[0] = -84.570699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223359378, states[0] = -26.314207, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1234419558, states[0] = -84.547378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245480430, states[0] = -22.085656, states[40]= 0.000228
Saving checkpoint... 
Iteration: 1256541837, states[0] = -84.539916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267602298, states[0] = -18.657742, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1278662837, states[0] = -84.528716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289723207, states[0] = -14.119710, states[40]= 0.000294
Saving checkpoint... 
Iteration: 1300785319, states[0] = -84.521239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311848159, states[0] = -14.066086, states[40]= 0.000295
Saving checkpoint... 
Iteration: 1322908497, states[0] = -84.515577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333969028, states[0] = -9.606982, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1345031417, states[0] = -84.509029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1356080997, states[0] = 1.475367, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1367123902, states[0] = -84.389678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378161757, states[0] = 25.192510, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1389196155, states[0] = -84.067133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400241648, states[0] = -84.667908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411285467, states[0] = -81.192715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422328017, states[0] = -84.614125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433371487, states[0] = -38.974841, states[40]= 0.000116
Saving checkpoint... 
Iteration: 1444414438, states[0] = -84.529947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455458125, states[0] = -0.026847, states[40]= 0.000331
Saving checkpoint... 
Iteration: 1466503108, states[0] = -84.405935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477556577, states[0] = 15.609112, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1488605055, states[0] = -84.293641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499648469, states[0] = 30.460457, states[40]= 0.000521
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.550599
 - CaMKt in component CaMK (millimolar): 0.030080
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.932365
 - nass in component intracellular_ions (millimolar): 6.932507
 - ki in component intracellular_ions (millimolar): 144.773593
 - kss in component intracellular_ions (millimolar): 144.773566
 - cansr in component intracellular_ions (millimolar): 1.970230
 - cajsr in component intracellular_ions (millimolar): 1.806212
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.010258
 - hf in component INa (dimensionless): 0.572389
 - hs in component INa (dimensionless): 0.572282
 - j in component INa (dimensionless): 0.571707
 - hsp in component INa (dimensionless): 0.325513
 - jp in component INa (dimensionless): 0.571278
 - mL in component INaL (dimensionless): 0.000354
 - hL in component INaL (dimensionless): 0.362470
 - hLp in component INaL (dimensionless): 0.161524
 - a in component Ito (dimensionless): 0.001253
 - iF in component Ito (dimensionless): 0.999202
 - iS in component Ito (dimensionless): 0.417002
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999202
 - iSp in component Ito (dimensionless): 0.453789
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.864689
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.997978
 - jca in component ICaL (dimensionless): 0.999325
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005037
 - xrf in component IKr (dimensionless): 0.000102
 - xrs in component IKr (dimensionless): 0.630118
 - xs1 in component IKs (dimensionless): 0.353498
 - xs2 in component IKs (dimensionless): 0.000280
 - xk1 in component IK1 (dimensionless): 0.996788
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
08:52:08 (3392): called boinc_finish(0)

</stderr_txt>
]]>


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