𝕏

Task 55043815

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1
Workunit 26137635
Created 27 Jun 2024, 18:11:27 UTC
Sent 28 Jun 2024, 4:55:22 UTC
Report deadline 1 Jul 2024, 4:55:22 UTC
Received 28 Jun 2024, 18:31:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230596
Run time 2 hours 27 min 46 sec
CPU time 2 hours 26 min 27 sec
Validate state Valid
Credit 42.18
Device peak FLOPS 2.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.68 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.685500
     * GNaL_b in INaL: 0.005836
     * Gto_b in Ito: 0.092767
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033615
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.163750
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 72.249810
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036406
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11303358, states[0] = -93.906073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22766861, states[0] = -94.339728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34093330, states[0] = 17.826444, states[40]= 0.000020
Saving checkpoint... 
Iteration: 45469707, states[0] = -94.296037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56876945, states[0] = -94.377809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68133173, states[0] = -0.942570, states[40]= 0.000911
Saving checkpoint... 
Iteration: 79325019, states[0] = -94.047644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90630599, states[0] = -94.400368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101833971, states[0] = -94.408431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113085405, states[0] = 18.948148, states[40]= 0.000018
Saving checkpoint... 
Iteration: 124347927, states[0] = -94.147996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135554235, states[0] = -94.395365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146775344, states[0] = -94.417850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157924491, states[0] = -94.411974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169211075, states[0] = -52.671855, states[40]= 0.000698
Saving checkpoint... 
Iteration: 180423567, states[0] = -94.305035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191680612, states[0] = -94.417703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202803589, states[0] = -94.417767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214080486, states[0] = 20.667309, states[40]= 0.000011
Saving checkpoint... 
Iteration: 225402759, states[0] = -94.274044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236650731, states[0] = -94.414541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247856930, states[0] = -94.414350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259215728, states[0] = -56.951251, states[40]= 0.000383
Saving checkpoint... 
Iteration: 270598083, states[0] = -94.406123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282028959, states[0] = 33.333350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293374034, states[0] = -94.217003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304745096, states[0] = -94.415515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316241686, states[0] = -90.214285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 327619744, states[0] = -94.407553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338898153, states[0] = -94.408796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350265809, states[0] = -93.746285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361715279, states[0] = -94.413070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372957856, states[0] = -94.404047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384188020, states[0] = -35.439064, states[40]= 0.005074
Saving checkpoint... 
Iteration: 395523487, states[0] = -94.378329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406593101, states[0] = -94.399799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417822007, states[0] = -94.409241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429076737, states[0] = 22.095735, states[40]= 0.000007
Saving checkpoint... 
Iteration: 440332257, states[0] = -94.093197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451510745, states[0] = -94.369905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462737967, states[0] = -94.409248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 473973460, states[0] = -94.399094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485079927, states[0] = 20.876598, states[40]= 0.000010
Saving checkpoint... 
Iteration: 496329541, states[0] = -94.081154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507480615, states[0] = -94.349232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 518683444, states[0] = -94.405781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529867550, states[0] = -94.402765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541042863, states[0] = 32.136807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552336132, states[0] = -94.102058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563548244, states[0] = -94.381439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574817798, states[0] = -94.403142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586230792, states[0] = -73.038820, states[40]= 0.000036
Saving checkpoint... 
Iteration: 597652709, states[0] = -94.400595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608901523, states[0] = -94.397874, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.685500
     * GNaL_b in INaL: 0.005836
     * Gto_b in Ito: 0.092767
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033615
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.163750
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 72.249810
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036406
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 608901523
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.397874 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 620318422, states[0] = -94.032941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631729634, states[0] = -94.402494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643009708, states[0] = 28.553757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654306850, states[0] = -93.980336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665679388, states[0] = -94.399721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677000236, states[0] = -65.432797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688479218, states[0] = -94.340989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699987314, states[0] = -94.389256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711377904, states[0] = -94.208577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722715711, states[0] = -94.398684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734071196, states[0] = 24.147718, states[40]= 0.000003
Saving checkpoint... 
Iteration: 745323692, states[0] = -94.048984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756548229, states[0] = -94.373717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767983008, states[0] = -94.386792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 779360054, states[0] = -94.163865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790656138, states[0] = -94.393151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802043368, states[0] = 32.053650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813362004, states[0] = -94.167484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824738495, states[0] = -94.394799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836111343, states[0] = 7.739010, states[40]= 0.000245
Saving checkpoint... 
Iteration: 847452832, states[0] = -94.312548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858665992, states[0] = -94.391185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870065486, states[0] = 26.143175, states[40]= 0.000002
Saving checkpoint... 
Iteration: 881385321, states[0] = -94.216859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 892842096, states[0] = -94.389459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904136126, states[0] = -4.755095, states[40]= 0.001192
Saving checkpoint... 
Iteration: 915650174, states[0] = -94.387637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927075938, states[0] = 22.404828, states[40]= 0.000006
Saving checkpoint... 
Iteration: 938512958, states[0] = -94.351556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949992945, states[0] = -94.378929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961417703, states[0] = -94.267288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972858698, states[0] = -94.385515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984312052, states[0] = -93.990618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995744619, states[0] = -94.387989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007131405, states[0] = -2.017697, states[40]= 0.000991
Saving checkpoint... 
Iteration: 1018568755, states[0] = -94.369608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030054494, states[0] = 29.527690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041457429, states[0] = -94.309095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052815374, states[0] = -94.384173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064266231, states[0] = -93.719949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075799003, states[0] = -94.383798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087049159, states[0] = 30.877146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098517881, states[0] = -94.347604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109834789, states[0] = -94.381125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121283909, states[0] = -93.837258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132778471, states[0] = -94.382055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144432866, states[0] = -94.279374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155822203, states[0] = -94.379791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167253786, states[0] = -93.565428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178601505, states[0] = -94.370604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190024386, states[0] = 33.133789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201396770, states[0] = -94.225119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212838700, states[0] = -94.376839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224269192, states[0] = -93.735151, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_595_1_r15907089_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.685500
     * GNaL_b in INaL: 0.005836
     * Gto_b in Ito: 0.092767
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033615
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.163750
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 72.249810
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036406
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1224269192
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.735151 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1235573063, states[0] = -94.362049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246939747, states[0] = -94.370232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258246175, states[0] = -92.736397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269697427, states[0] = -94.376381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281047434, states[0] = 31.264806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292391808, states[0] = -94.212599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303796984, states[0] = -94.374744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1315142394, states[0] = -8.740751, states[40]= 0.001321
Saving checkpoint... 
Iteration: 1326675126, states[0] = -94.373087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338057151, states[0] = 28.781270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349438876, states[0] = -94.278012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360797390, states[0] = -94.372465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372232773, states[0] = -75.876079, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1383575139, states[0] = -94.356676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394879816, states[0] = -94.367630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406180910, states[0] = -31.075443, states[40]= 0.006823
Saving checkpoint... 
Iteration: 1417465981, states[0] = -94.301495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428854194, states[0] = -94.367560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1440174576, states[0] = -27.647371, states[40]= 0.007397
Saving checkpoint... 
Iteration: 1451534006, states[0] = -94.340633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462872658, states[0] = -94.365297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474223966, states[0] = -64.601064, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1485547240, states[0] = -94.344253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496775505, states[0] = -94.367604, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.232499
 - CaMKt in component CaMK (millimolar): 0.009919
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 8.123944
 - nass in component intracellular_ions (millimolar): 8.124128
 - ki in component intracellular_ions (millimolar): 143.373176
 - kss in component intracellular_ions (millimolar): 143.373150
 - cansr in component intracellular_ions (millimolar): 2.168192
 - cajsr in component intracellular_ions (millimolar): 2.171026
 - cai in component intracellular_ions (millimolar): 0.000109
 - m in component INa (dimensionless): 0.003871
 - hf in component INa (dimensionless): 0.867892
 - hs in component INa (dimensionless): 0.867894
 - j in component INa (dimensionless): 0.867908
 - hsp in component INa (dimensionless): 0.703450
 - jp in component INa (dimensionless): 0.867916
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.710939
 - hLp in component INaL (dimensionless): 0.494357
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.874431
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.916191
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.960770
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005763
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.121377
 - xs1 in component IKs (dimensionless): 0.165527
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997507
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
14:27:41 (7224): called boinc_finish(0)

</stderr_txt>
]]>


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