𝕏

Task 55043806

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0
Workunit 26137631
Created 27 Jun 2024, 18:11:27 UTC
Sent 28 Jun 2024, 4:55:22 UTC
Report deadline 1 Jul 2024, 4:55:22 UTC
Received 28 Jun 2024, 20:43:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230596
Run time 2 hours 28 min 50 sec
CPU time 2 hours 27 min 49 sec
Validate state Valid
Credit 42.10
Device peak FLOPS 2.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.68 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11229779, states[0] = -39.459064, states[40]= 0.001561
Saving checkpoint... 
Iteration: 22772931, states[0] = -94.312347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34069818, states[0] = 26.282118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45369705, states[0] = -94.138147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56816139, states[0] = -94.348588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68164992, states[0] = -19.198679, states[40]= 0.002027
Saving checkpoint... 
Iteration: 79511167, states[0] = -94.328352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90882891, states[0] = -94.368532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102178559, states[0] = -27.474278, states[40]= 0.005383
Saving checkpoint... 
Iteration: 113471602, states[0] = -94.318417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 124762906, states[0] = -94.380500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136075647, states[0] = 22.434061, states[40]= 0.000003
Saving checkpoint... 
Iteration: 147490580, states[0] = -94.335173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158911886, states[0] = -94.378805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170286156, states[0] = -93.915915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181666521, states[0] = -94.381271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192855169, states[0] = -94.381513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204259187, states[0] = -93.750818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215638178, states[0] = -94.378513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227028794, states[0] = 34.488653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238221594, states[0] = -60.700246, states[40]= 0.000160
Saving checkpoint... 
Iteration: 249522536, states[0] = -94.350848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260980606, states[0] = -94.374490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272381841, states[0] = -94.218536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283879828, states[0] = -94.378428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295348227, states[0] = -94.145216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306825131, states[0] = -94.379675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318198661, states[0] = -41.532515, states[40]= 0.002012
Saving checkpoint... 
Iteration: 329609691, states[0] = -94.371593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341045055, states[0] = 32.201981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352471537, states[0] = -94.319876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363905447, states[0] = -94.374791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375461575, states[0] = -94.311768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386723711, states[0] = -94.378130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397992189, states[0] = -94.369559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409369222, states[0] = -94.189924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420733683, states[0] = -94.377150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432184956, states[0] = -32.353159, states[40]= 0.004540
Saving checkpoint... 
Iteration: 443712086, states[0] = -94.376036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455012713, states[0] = 32.278213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466398564, states[0] = -94.239677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477724247, states[0] = -94.375170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489081613, states[0] = 20.009763, states[40]= 0.000007
Saving checkpoint... 
Iteration: 500276037, states[0] = -93.852605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511473738, states[0] = -94.316203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522714533, states[0] = -94.373532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533958176, states[0] = -94.366810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545201793, states[0] = -43.896014, states[40]= 0.001541
Saving checkpoint... 
Iteration: 556311244, states[0] = -94.018410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567594308, states[0] = -94.361230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578788633, states[0] = -94.371717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589946174, states[0] = -94.365551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601134045, states[0] = -3.072980, states[40]= 0.000636
Saving checkpoint... 
Iteration: 612371824, states[0] = -94.188503, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 612371824
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.188503 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 623587069, states[0] = -94.357992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634703783, states[0] = -94.369578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645832248, states[0] = -94.368428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656884384, states[0] = -94.366140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668017332, states[0] = 33.703440, states[40]= -0.000000
Saving checkpoint... 
Iteration: 679226121, states[0] = -65.403757, states[40]= 0.000080
Saving checkpoint... 
Iteration: 690542526, states[0] = -94.344051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701899809, states[0] = -94.364014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713143763, states[0] = -8.944298, states[40]= 0.000822
Saving checkpoint... 
Iteration: 724435863, states[0] = -94.277442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735673273, states[0] = -94.364898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 747073180, states[0] = 23.267829, states[40]= 0.000002
Saving checkpoint... 
Iteration: 758275101, states[0] = -93.838586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769636433, states[0] = -94.360722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780846021, states[0] = -94.363561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 791902082, states[0] = -94.360977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802949989, states[0] = -94.358409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814046438, states[0] = 31.882999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825058350, states[0] = 28.493808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836055952, states[0] = 29.250146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847135823, states[0] = -4.060257, states[40]= 0.000683
Saving checkpoint... 
Iteration: 858150411, states[0] = -13.380619, states[40]= 0.000897
Saving checkpoint... 
Iteration: 869285103, states[0] = -93.889652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880378219, states[0] = -94.192015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891325103, states[0] = -94.057383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902546242, states[0] = -94.338348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913751766, states[0] = -94.361153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924833762, states[0] = -94.359284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 935825513, states[0] = -94.359177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947081553, states[0] = 20.039911, states[40]= 0.000006
Saving checkpoint... 
Iteration: 958183609, states[0] = -31.533237, states[40]= 0.004741
Saving checkpoint... 
Iteration: 969215494, states[0] = -55.134276, states[40]= 0.000358
Saving checkpoint... 
Iteration: 980359096, states[0] = -94.149092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991497626, states[0] = -94.315013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002619716, states[0] = -94.351087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013835994, states[0] = -94.356305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025023014, states[0] = 34.436071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036317781, states[0] = -94.027019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047548658, states[0] = -94.334364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058771386, states[0] = -94.356300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070057484, states[0] = 28.773587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081282376, states[0] = -93.868123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092538475, states[0] = -94.329528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103861620, states[0] = -94.352460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115043981, states[0] = 32.450931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126284503, states[0] = -93.877851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137677380, states[0] = -94.352020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148996269, states[0] = -94.344856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160160888, states[0] = -19.863849, states[40]= 0.002031
Saving checkpoint... 
Iteration: 1171489261, states[0] = -94.304453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1182796816, states[0] = -94.351866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193952051, states[0] = -94.345573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205334030, states[0] = -94.075394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216774226, states[0] = -94.351125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228158925, states[0] = -18.755105, states[40]= 0.001634
Saving checkpoint... 
Iteration: 1239386863, states[0] = -94.195576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1250552102, states[0] = -94.328799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261806637, states[0] = -94.349057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273011249, states[0] = 31.573820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284325286, states[0] = -94.044933, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_2000-conf_195_0_r505666917_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1284325286
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.044933 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1295586258, states[0] = -94.335885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306878111, states[0] = -94.345197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318079682, states[0] = 20.779406, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1329255879, states[0] = -93.673966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340346827, states[0] = -94.107039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351516296, states[0] = -94.312336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362674162, states[0] = -94.344498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373968450, states[0] = -94.338893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385190909, states[0] = -36.038485, states[40]= 0.003450
Saving checkpoint... 
Iteration: 1396498265, states[0] = -94.302102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407661306, states[0] = -94.342168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419063711, states[0] = 26.708409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430243648, states[0] = -91.316760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441538822, states[0] = -94.318246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452790131, states[0] = -94.343173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464084474, states[0] = 18.888050, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1475217589, states[0] = -56.935218, states[40]= 0.000276
Saving checkpoint... 
Iteration: 1486478774, states[0] = -94.287662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497707945, states[0] = -94.341565, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.209177
 - CaMKt in component CaMK (millimolar): 0.009031
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 8.119668
 - nass in component intracellular_ions (millimolar): 8.119835
 - ki in component intracellular_ions (millimolar): 143.457979
 - kss in component intracellular_ions (millimolar): 143.457956
 - cansr in component intracellular_ions (millimolar): 2.055205
 - cajsr in component intracellular_ions (millimolar): 2.057536
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003881
 - hf in component INa (dimensionless): 0.867452
 - hs in component INa (dimensionless): 0.867454
 - j in component INa (dimensionless): 0.867465
 - hsp in component INa (dimensionless): 0.702648
 - jp in component INa (dimensionless): 0.867471
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710273
 - hLp in component INaL (dimensionless): 0.493557
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.873891
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.915738
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.960333
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004943
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.122019
 - xs1 in component IKs (dimensionless): 0.166630
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997513
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:37:58 (5052): called boinc_finish(0)

</stderr_txt>
]]>


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