Task 55043627

Name	HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1
Workunit	26137541
Created	27 Jun 2024, 18:11:22 UTC
Sent	28 Jun 2024, 4:54:57 UTC
Report deadline	1 Jul 2024, 4:54:57 UTC
Received	28 Jun 2024, 14:42:13 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	230596
Run time	2 hours 26 min 11 sec
CPU time	2 hours 25 min 2 sec
Validate state	Valid
Credit	43.21
Device peak FLOPS	2.68 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	11.68 MB
Peak swap size	6.23 MB
Peak disk usage	0.03 MB
Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12537718, states[0] = 24.774334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25772787, states[0] = -94.441961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39083853, states[0] = 5.718252, states[40]= 0.000134
Saving checkpoint... 
Iteration: 52346778, states[0] = -94.590722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65552159, states[0] = 20.231482, states[40]= 0.000002
Saving checkpoint... 
Iteration: 77659287, states[0] = -92.914934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88592123, states[0] = -3.367131, states[40]= 0.000654
Saving checkpoint... 
Iteration: 99610737, states[0] = -26.650863, states[40]= 0.000817
Saving checkpoint... 
Iteration: 110469071, states[0] = -94.680506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121484148, states[0] = -94.683829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132508105, states[0] = 19.584053, states[40]= 0.000002
Saving checkpoint... 
Iteration: 143561323, states[0] = 16.226301, states[40]= 0.000014
Saving checkpoint... 
Iteration: 154539405, states[0] = 23.037075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165573718, states[0] = 9.935611, states[40]= 0.000099
Saving checkpoint... 
Iteration: 176521700, states[0] = 23.790828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187617850, states[0] = -36.483407, states[40]= 0.000777
Saving checkpoint... 
Iteration: 198737079, states[0] = -94.393426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209933004, states[0] = -94.673894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220974654, states[0] = -94.680837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232062416, states[0] = 15.700597, states[40]= 0.000017
Saving checkpoint... 
Iteration: 243056302, states[0] = 18.245962, states[40]= 0.000006
Saving checkpoint... 
Iteration: 254222759, states[0] = -94.322752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265188372, states[0] = -94.094061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276320906, states[0] = -94.595307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287407284, states[0] = -94.660369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298583847, states[0] = 3.235356, states[40]= 0.000365
Saving checkpoint... 
Iteration: 309784883, states[0] = -94.532075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320860376, states[0] = -94.631909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331888512, states[0] = -94.648808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343017653, states[0] = 23.176205, states[40]= -0.000000
Saving checkpoint... 
Iteration: 354071766, states[0] = 11.014754, states[40]= 0.000075
Saving checkpoint... 
Iteration: 365112622, states[0] = -29.788451, states[40]= 0.000911
Saving checkpoint... 
Iteration: 376056279, states[0] = 18.256837, states[40]= 0.000006
Saving checkpoint... 
Iteration: 387039632, states[0] = 22.982918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398087485, states[0] = 0.290944, states[40]= 0.000527
Saving checkpoint... 
Iteration: 409084847, states[0] = 2.466592, states[40]= 0.000407
Saving checkpoint... 
Iteration: 420036296, states[0] = 23.507963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431084423, states[0] = 2.798428, states[40]= 0.000388
Saving checkpoint... 
Iteration: 442049751, states[0] = 20.506903, states[40]= 0.000002
Saving checkpoint... 
Iteration: 453092175, states[0] = -4.182185, states[40]= 0.000736
Saving checkpoint... 
Iteration: 464101337, states[0] = -15.273749, states[40]= 0.000693
Saving checkpoint... 
Iteration: 475285640, states[0] = -94.521823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486344998, states[0] = -94.607136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497342801, states[0] = -94.604268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508262756, states[0] = -94.462197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519385594, states[0] = -94.633966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530566373, states[0] = 13.833110, states[40]= 0.000033
Saving checkpoint... 
Iteration: 541592199, states[0] = -4.201548, states[40]= 0.000734
Saving checkpoint... 
Iteration: 552676958, states[0] = -93.971324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563626922, states[0] = -48.556041, states[40]= 0.000299
Saving checkpoint... 
Iteration: 574657497, states[0] = -92.716764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585775113, states[0] = -94.489821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596738496, states[0] = -94.370958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607825324, states[0] = -94.577239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618889880, states[0] = -94.629082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629941547, states[0] = -94.646344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641078094, states[0] = 7.261531, states[40]= 0.000180
Saving checkpoint... 
Iteration: 652195080, states[0] = -94.118785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662997610, states[0] = -94.651698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674285908, states[0] = -94.508140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685598936, states[0] = -12.151078, states[40]= 0.000747
Saving checkpoint... 
Iteration: 696693456, states[0] = -94.103058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707853690, states[0] = -94.599015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719031655, states[0] = 23.977721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730132471, states[0] = -56.052278, states[40]= 0.000130


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 730132471
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -56.052278 (After loading)
 - states[40]: 0.000130 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 741102680, states[0] = -17.000267, states[40]= 0.000668
Saving checkpoint... 
Iteration: 752391225, states[0] = -94.620287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763618260, states[0] = -37.006607, states[40]= 0.000752
Saving checkpoint... 
Iteration: 773968893, states[0] = -94.641012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785152063, states[0] = -87.915129, states[40]= 0.000002
Saving checkpoint... 
Iteration: 796461488, states[0] = -94.638320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807741154, states[0] = -94.366521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818916838, states[0] = -94.626039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830083811, states[0] = 3.285275, states[40]= 0.000359
Saving checkpoint... 
Iteration: 841343502, states[0] = -94.580391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852490230, states[0] = -94.637702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863676363, states[0] = -93.942508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874882930, states[0] = -94.607204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886098410, states[0] = -11.464728, states[40]= 0.000758
Saving checkpoint... 
Iteration: 897299086, states[0] = -94.517690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908541160, states[0] = 22.703871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919686001, states[0] = -94.026055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930901428, states[0] = -94.612226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942063307, states[0] = 15.312007, states[40]= 0.000020
Saving checkpoint... 
Iteration: 953330935, states[0] = -94.559247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964554689, states[0] = 18.864736, states[40]= 0.000004
Saving checkpoint... 
Iteration: 975748731, states[0] = -94.383075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987055380, states[0] = 18.611795, states[40]= 0.000005
Saving checkpoint... 
Iteration: 998091575, states[0] = -3.525844, states[40]= 0.000705
Saving checkpoint... 
Iteration: 1009307534, states[0] = -94.523797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020618616, states[0] = -37.448088, states[40]= 0.000731
Saving checkpoint... 
Iteration: 1031824896, states[0] = -94.546460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042897833, states[0] = -94.602709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054028031, states[0] = 24.113879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065176398, states[0] = -93.927962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076406521, states[0] = -94.603970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087572092, states[0] = 10.857961, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1098835991, states[0] = -94.554435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110090576, states[0] = -2.518243, states[40]= 0.000663
Saving checkpoint... 
Iteration: 1121328058, states[0] = -94.543904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132412308, states[0] = -94.602164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143541607, states[0] = 22.618409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154778638, states[0] = -94.457478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165964415, states[0] = -94.612507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177095222, states[0] = -7.529294, states[40]= 0.000788
Saving checkpoint... 
Iteration: 1188187925, states[0] = -94.022497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199233060, states[0] = -94.303985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210136268, states[0] = -61.198828, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1221279368, states[0] = -94.454450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232348037, states[0] = -94.556774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243410193, states[0] = -94.593524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254507925, states[0] = 19.449699, states[40]= -0.000001
Saving checkpoint... 
Iteration: 1265521454, states[0] = 23.775620, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1276637661, states[0] = -63.149510, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1287679459, states[0] = -93.940790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298812806, states[0] = -94.511093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309659237, states[0] = -93.143434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320812442, states[0] = -94.508979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331819864, states[0] = -94.518586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342698371, states[0] = -94.092702, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_1000-conf_195_1_r1387074949_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.342015
     * GNaL_b in INaL: 0.006441
     * Gto_b in Ito: 0.074232
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033901
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.171134
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 71.189727
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054782
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1342698371
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.092702 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1353810770, states[0] = -94.504137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364867284, states[0] = -94.562585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376000126, states[0] = -79.152080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387198013, states[0] = -94.086827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398475501, states[0] = -94.597461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409659966, states[0] = -93.277459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420764504, states[0] = -94.401643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432018344, states[0] = 23.322052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443238570, states[0] = -94.310129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454433609, states[0] = -94.585874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465557680, states[0] = 17.740435, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1476577790, states[0] = 7.486348, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1487606717, states[0] = -22.163409, states[40]= 0.000708
Saving checkpoint... 
Iteration: 1498600253, states[0] = -13.780622, states[40]= 0.000707
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.468301
 - CaMKt in component CaMK (millimolar): 0.025847
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 7.848944
 - nass in component intracellular_ions (millimolar): 7.849107
 - ki in component intracellular_ions (millimolar): 143.225099
 - kss in component intracellular_ions (millimolar): 143.225062
 - cansr in component intracellular_ions (millimolar): 3.097701
 - cajsr in component intracellular_ions (millimolar): 3.074254
 - cai in component intracellular_ions (millimolar): 0.000108
 - m in component INa (dimensionless): 0.003780
 - hf in component INa (dimensionless): 0.872272
 - hs in component INa (dimensionless): 0.872269
 - j in component INa (dimensionless): 0.872247
 - hsp in component INa (dimensionless): 0.711439
 - jp in component INa (dimensionless): 0.872227
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.699540
 - hLp in component INaL (dimensionless): 0.442808
 - a in component Ito (dimensionless): 0.000642
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.999859
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999859
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.917810
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005960
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327053
 - xs1 in component IKs (dimensionless): 0.267625
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997449
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:35:18 (13904): called boinc_finish(0)

</stderr_txt>
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