𝕏

Task 55043173

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1
Workunit 26137314
Created 27 Jun 2024, 18:11:12 UTC
Sent 28 Jun 2024, 4:55:22 UTC
Report deadline 1 Jul 2024, 4:55:22 UTC
Received 28 Jun 2024, 22:59:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230596
Run time 2 hours 28 min 30 sec
CPU time 2 hours 27 min 25 sec
Validate state Valid
Credit 43.43
Device peak FLOPS 2.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.68 MB
Peak swap size 6.22 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.949209
     * GNaL_b in INaL: 0.006306
     * Gto_b in Ito: 0.082691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033604
     * GKs_b in IKs: 0.002062
     * GK1_b in IK1: 0.150202
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 67.820236
     * GKb_b in IKb: 0.003720
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038367
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11348375, states[0] = -94.733945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22620982, states[0] = -36.426554, states[40]= 0.000486
Saving checkpoint... 
Iteration: 33897421, states[0] = -94.723608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45267604, states[0] = -94.559732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56700020, states[0] = -94.330371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68118929, states[0] = -33.965150, states[40]= 0.000673
Saving checkpoint... 
Iteration: 79493237, states[0] = -94.755973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90809833, states[0] = -94.636782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102200134, states[0] = -94.330535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113596404, states[0] = -11.286129, states[40]= 0.002447
Saving checkpoint... 
Iteration: 124803751, states[0] = -94.627666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135938593, states[0] = -94.740081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147206383, states[0] = -94.358549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158321933, states[0] = -94.653354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169441013, states[0] = -94.740930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180510038, states[0] = 28.032985, states[40]= 0.048436
Saving checkpoint... 
Iteration: 191720439, states[0] = -94.415888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202952069, states[0] = -94.744747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214174716, states[0] = -93.661785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225299063, states[0] = -94.619913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236430043, states[0] = -94.736358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247549162, states[0] = 17.479291, states[40]= 0.003262
Saving checkpoint... 
Iteration: 258721157, states[0] = -94.418397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269909448, states[0] = -94.726609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281101570, states[0] = -16.571374, states[40]= 0.001561
Saving checkpoint... 
Iteration: 292222304, states[0] = -94.422614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303312682, states[0] = -94.640401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314452925, states[0] = -94.744643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325674386, states[0] = -93.608467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337030217, states[0] = 24.425389, states[40]= 0.002064
Saving checkpoint... 
Iteration: 348348583, states[0] = -94.682511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359641618, states[0] = -57.887656, states[40]= 0.000025
Saving checkpoint... 
Iteration: 370882988, states[0] = -94.710490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382227937, states[0] = -94.442889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393623525, states[0] = -38.607441, states[40]= 0.000406
Saving checkpoint... 
Iteration: 404877097, states[0] = -94.706240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416157993, states[0] = -78.265950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427396396, states[0] = -94.718804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438581082, states[0] = 1.519362, states[40]= 0.004823
Saving checkpoint... 
Iteration: 449597416, states[0] = -12.311846, states[40]= 0.002235
Saving checkpoint... 
Iteration: 460667548, states[0] = -90.750642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471701203, states[0] = -94.334322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482691724, states[0] = -94.286058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493819462, states[0] = -94.648975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504953545, states[0] = -94.744165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515962445, states[0] = -94.746925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527078322, states[0] = 3.286470, states[40]= 0.004890
Saving checkpoint... 
Iteration: 538177920, states[0] = -93.996126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549203386, states[0] = -94.343920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560233149, states[0] = -94.460280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571431308, states[0] = -94.735688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582574593, states[0] = 5.500979, states[40]= 0.004871
Saving checkpoint... 
Iteration: 593651061, states[0] = -68.764730, states[40]= 0.000004
Saving checkpoint... 
Iteration: 604725966, states[0] = -94.435003, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.949209
     * GNaL_b in INaL: 0.006306
     * Gto_b in Ito: 0.082691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033604
     * GKs_b in IKs: 0.002062
     * GK1_b in IK1: 0.150202
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 67.820236
     * GKb_b in IKb: 0.003720
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038367
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 604725966
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.435003 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 615744052, states[0] = -94.494750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626846181, states[0] = -94.679152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637975623, states[0] = -94.750179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649161723, states[0] = -83.888147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660396107, states[0] = -94.717796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671454279, states[0] = -94.743809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682642571, states[0] = -58.934719, states[40]= 0.000021
Saving checkpoint... 
Iteration: 693854271, states[0] = -94.686623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705031662, states[0] = 23.961954, states[40]= 0.002116
Saving checkpoint... 
Iteration: 716116872, states[0] = -31.938531, states[40]= 0.000805
Saving checkpoint... 
Iteration: 727250577, states[0] = -94.513225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738475764, states[0] = -94.749855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749510245, states[0] = 28.013807, states[40]= 0.045255
Saving checkpoint... 
Iteration: 760723148, states[0] = -94.424071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771825915, states[0] = -94.656188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783049979, states[0] = 17.149196, states[40]= 0.003328
Saving checkpoint... 
Iteration: 794172444, states[0] = -93.187805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805371852, states[0] = -94.700911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816592377, states[0] = -7.384649, states[40]= 0.003348
Saving checkpoint... 
Iteration: 827827511, states[0] = -94.657932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839038161, states[0] = 21.707602, states[40]= 0.002462
Saving checkpoint... 
Iteration: 850128382, states[0] = -43.616676, states[40]= 0.000213
Saving checkpoint... 
Iteration: 861346286, states[0] = -94.678413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872449241, states[0] = -94.741397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883649031, states[0] = -66.289631, states[40]= 0.000006
Saving checkpoint... 
Iteration: 894763530, states[0] = -94.546317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906076292, states[0] = 4.514692, states[40]= 0.004893
Saving checkpoint... 
Iteration: 917248136, states[0] = -94.505630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928481945, states[0] = -94.750733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939593628, states[0] = -8.564035, states[40]= 0.003068
Saving checkpoint... 
Iteration: 950733671, states[0] = -94.460614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961852464, states[0] = -94.683993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973045017, states[0] = 19.122048, states[40]= 0.002940
Saving checkpoint... 
Iteration: 984280965, states[0] = -94.584384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995457274, states[0] = -94.743611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006638029, states[0] = -53.966645, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1017791479, states[0] = -94.604100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029055120, states[0] = 15.008431, states[40]= 0.003742
Saving checkpoint... 
Iteration: 1040228620, states[0] = -94.442916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051320437, states[0] = -94.648245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062483634, states[0] = -94.750660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073495587, states[0] = -94.753304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084620237, states[0] = -35.291577, states[40]= 0.000590
Saving checkpoint... 
Iteration: 1095655785, states[0] = -75.037377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106848640, states[0] = -94.679839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117956787, states[0] = -94.743018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129022838, states[0] = 26.471336, states[40]= 0.002318
Saving checkpoint... 
Iteration: 1140183479, states[0] = -94.200207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151263930, states[0] = -94.546355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162354971, states[0] = -94.685576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173491529, states[0] = -94.752074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184476533, states[0] = -94.748456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195775317, states[0] = -94.571981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207031541, states[0] = 24.001982, states[40]= 0.002111
Saving checkpoint... 
Iteration: 1218224917, states[0] = -94.428947, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT-conf_494_1_r948248348_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.949209
     * GNaL_b in INaL: 0.006306
     * Gto_b in Ito: 0.082691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033604
     * GKs_b in IKs: 0.002062
     * GK1_b in IK1: 0.150202
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 67.820236
     * GKb_b in IKb: 0.003720
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038367
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1218224917
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.428947 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1229641877, states[0] = -58.167654, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1240998488, states[0] = -94.753303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252325185, states[0] = -94.653557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263597759, states[0] = -12.657678, states[40]= 0.002167
Saving checkpoint... 
Iteration: 1274939224, states[0] = -94.736317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286267546, states[0] = -94.554409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297674111, states[0] = -93.555843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309092055, states[0] = -7.085430, states[40]= 0.003419
Saving checkpoint... 
Iteration: 1320619774, states[0] = -34.827634, states[40]= 0.000619
Saving checkpoint... 
Iteration: 1331957594, states[0] = -94.742506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343372415, states[0] = -94.699406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354776779, states[0] = -94.574489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366187720, states[0] = -94.253693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377587116, states[0] = -2.848650, states[40]= 0.004310
Saving checkpoint... 
Iteration: 1389010741, states[0] = 27.976000, states[40]= 0.038482
Saving checkpoint... 
Iteration: 1400372920, states[0] = -94.699583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411751580, states[0] = -94.513528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423049985, states[0] = 17.147503, states[40]= 0.003329
Saving checkpoint... 
Iteration: 1434419942, states[0] = -94.727594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445804287, states[0] = -94.623846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457215774, states[0] = -94.393027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468572867, states[0] = 6.470882, states[40]= 0.004829
Saving checkpoint... 
Iteration: 1479793565, states[0] = -94.606105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491085179, states[0] = -1.357791, states[40]= 0.004541
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.628556
 - CaMKt in component CaMK (millimolar): 0.012439
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.865181
 - nass in component intracellular_ions (millimolar): 6.865277
 - ki in component intracellular_ions (millimolar): 145.021218
 - kss in component intracellular_ions (millimolar): 145.021197
 - cansr in component intracellular_ions (millimolar): 1.656183
 - cajsr in component intracellular_ions (millimolar): 1.615171
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003720
 - hf in component INa (dimensionless): 0.875177
 - hs in component INa (dimensionless): 0.875169
 - j in component INa (dimensionless): 0.875116
 - hsp in component INa (dimensionless): 0.716783
 - jp in component INa (dimensionless): 0.875079
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.700970
 - hLp in component INaL (dimensionless): 0.439291
 - a in component Ito (dimensionless): 0.000635
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.614449
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.685369
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.918581
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999846
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003022
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.366301
 - xs1 in component IKs (dimensionless): 0.261683
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997408
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:41:29 (10024): called boinc_finish(0)

</stderr_txt>
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