𝕏

Task 55031885

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0
Workunit 26131676
Created 27 Jun 2024, 18:06:02 UTC
Sent 28 Jun 2024, 3:17:38 UTC
Report deadline 1 Jul 2024, 3:17:38 UTC
Received 29 Jun 2024, 20:03:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220129
Run time 2 hours 44 min 43 sec
CPU time 2 hours 11 min 38 sec
Validate state Valid
Credit 42.37
Device peak FLOPS 3.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.77 MB
Peak swap size 4.10 GB
Peak disk usage 0.05 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.935035
     * GNaL_b in INaL: 0.005177
     * Gto_b in Ito: 0.071379
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030370
     * GKs_b in IKs: 0.002017
     * GK1_b in IK1: 0.153089
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 69.243128
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022819
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5003559, states[0] = -94.107891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 10876635, states[0] = -93.940120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15161723, states[0] = -45.171056, states[40]= 0.000337
Saving checkpoint... 
Iteration: 19974678, states[0] = -93.943435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24294681, states[0] = -93.653049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29945186, states[0] = -93.933603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33507456, states[0] = -93.917593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38239446, states[0] = -93.946699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43231236, states[0] = -93.923950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48215824, states[0] = -89.722035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53140708, states[0] = -93.933694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58378904, states[0] = -93.912026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63368894, states[0] = -93.774277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68774877, states[0] = -93.914773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73343424, states[0] = -93.911656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78401837, states[0] = -93.819763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82902163, states[0] = -93.819972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87926732, states[0] = -93.929983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92851250, states[0] = -93.910653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98473012, states[0] = -93.927656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103391694, states[0] = -93.908944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109053267, states[0] = -93.923663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113287250, states[0] = -93.934249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118725642, states[0] = -92.861561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123609712, states[0] = -93.926148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128388238, states[0] = -93.931118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133119876, states[0] = -93.920274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137817815, states[0] = -93.911523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143015422, states[0] = -93.901931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147066392, states[0] = 18.362880, states[40]= 0.001453
Saving checkpoint... 
Iteration: 151355842, states[0] = -93.909949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156270185, states[0] = -93.491537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160899450, states[0] = -93.815822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166051529, states[0] = -93.923391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170583271, states[0] = -93.921839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175380947, states[0] = -93.908886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181228554, states[0] = -93.915081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186077289, states[0] = 14.034703, states[40]= 0.002327
Saving checkpoint... 
Iteration: 191305831, states[0] = -93.933489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196503513, states[0] = 38.821707, states[40]= 0.532809
Saving checkpoint... 
Iteration: 201775179, states[0] = -93.933964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206179567, states[0] = -93.932363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210809790, states[0] = -93.933333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215861502, states[0] = -93.909486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220415959, states[0] = -93.907432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225261812, states[0] = -93.453128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230054131, states[0] = -93.914434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235029620, states[0] = -93.924213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239509498, states[0] = -93.925172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244657922, states[0] = -38.620023, states[40]= 0.001174
Saving checkpoint... 
Iteration: 250380794, states[0] = -93.908643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255372443, states[0] = -93.777351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259701635, states[0] = -73.375654, states[40]= 0.000006
Saving checkpoint... 
Iteration: 265612847, states[0] = -4.581760, states[40]= 0.003931
Saving checkpoint... 
Iteration: 269797724, states[0] = -93.911859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275240132, states[0] = -93.933824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279827619, states[0] = -93.932660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285563240, states[0] = -93.916613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290426384, states[0] = -93.928903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295456204, states[0] = -93.905772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300367185, states[0] = -93.768536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305832348, states[0] = -93.910355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311319488, states[0] = -93.932790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316975425, states[0] = -93.881717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322047514, states[0] = -93.923088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327029984, states[0] = 30.449810, states[40]= 0.000270
Saving checkpoint... 
Iteration: 332430276, states[0] = -93.928608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337353904, states[0] = -93.909416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341058552, states[0] = -93.915272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345296940, states[0] = -93.595548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350194247, states[0] = -93.932603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355525886, states[0] = 31.359688, states[40]= 0.000408
Saving checkpoint... 
Iteration: 360638848, states[0] = -93.928854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365479474, states[0] = -93.926239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371268080, states[0] = -93.933522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376561832, states[0] = 20.081988, states[40]= 0.001164
Saving checkpoint... 
Iteration: 380869044, states[0] = -93.908707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386786616, states[0] = -93.911977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391382434, states[0] = -93.908168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396742208, states[0] = -93.933483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401627176, states[0] = -93.919036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407077590, states[0] = -93.919522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412049493, states[0] = -93.922732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416885132, states[0] = -93.907992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421030083, states[0] = -93.923646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425805195, states[0] = -93.911099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430335872, states[0] = -93.909853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434831964, states[0] = -93.909995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439876141, states[0] = -93.782649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444973843, states[0] = -93.926276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450518075, states[0] = -93.902003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455179168, states[0] = -93.931607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459650533, states[0] = -93.929643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464948144, states[0] = -93.905562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470103241, states[0] = -93.924019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474864259, states[0] = -93.930902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480294287, states[0] = -93.585923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484618987, states[0] = -9.221895, states[40]= 0.002982
Saving checkpoint... 
Iteration: 489259455, states[0] = -93.441138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493901843, states[0] = -93.817718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499307458, states[0] = -93.910794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504868766, states[0] = -93.930650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510041803, states[0] = 27.061940, states[40]= 0.000402
Saving checkpoint... 
Iteration: 515549490, states[0] = -93.922432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521081734, states[0] = -93.920043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525809317, states[0] = -93.932420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531582426, states[0] = -93.920151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536630607, states[0] = -93.918483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541497502, states[0] = -93.903650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546621513, states[0] = -93.926369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551642705, states[0] = -93.917872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556425540, states[0] = -93.906101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561289958, states[0] = -93.570103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565692448, states[0] = -64.787730, states[40]= 0.000024
Saving checkpoint... 
Iteration: 570944113, states[0] = -93.927294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576305632, states[0] = -93.623446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580870873, states[0] = -93.773853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585318514, states[0] = -93.661438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590824430, states[0] = -93.909844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595678634, states[0] = -54.084897, states[40]= 0.000141
Saving checkpoint... 
Iteration: 601210316, states[0] = -93.914640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605610746, states[0] = -93.919224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610788704, states[0] = -93.565319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615337157, states[0] = -93.708296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621182843, states[0] = -57.249529, states[40]= 0.000085
Saving checkpoint... 
Iteration: 625893242, states[0] = -93.806517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631225769, states[0] = -93.913870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635766686, states[0] = -93.912092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640523412, states[0] = 31.809392, states[40]= 0.000706
Saving checkpoint... 
Iteration: 645283651, states[0] = -93.545955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649868467, states[0] = -93.769674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655127658, states[0] = -93.918280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660098847, states[0] = 4.010473, states[40]= 0.004205
Saving checkpoint... 
Iteration: 665366411, states[0] = -93.930273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669147858, states[0] = -31.301464, states[40]= 0.002351
Saving checkpoint... 
Iteration: 673271441, states[0] = -93.911782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678206660, states[0] = -79.157381, states[40]= 0.000002
Saving checkpoint... 
Iteration: 683251649, states[0] = -93.932683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688196769, states[0] = -93.914995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692702394, states[0] = -93.914729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697411405, states[0] = -93.906206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702974654, states[0] = -93.925491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708272869, states[0] = -93.501519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713481351, states[0] = -93.925144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718472220, states[0] = -93.903992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723287705, states[0] = -93.561252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727948634, states[0] = -93.862410, states[40]= 0.000000
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Iteration: 733194118, states[0] = -93.914984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738356970, states[0] = -93.749041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743285854, states[0] = -93.932244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747765897, states[0] = -93.932450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752826352, states[0] = -93.909298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757363417, states[0] = -93.907832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762549688, states[0] = -93.911659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767495540, states[0] = -93.924310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772522939, states[0] = 31.885255, states[40]= 0.000801
Saving checkpoint... 
Iteration: 777529899, states[0] = -93.905407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782610202, states[0] = -93.918738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786733211, states[0] = -93.932284, states[40]= 0.000000
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Iteration: 791894514, states[0] = -93.906556, states[40]= 0.000000
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Iteration: 797090411, states[0] = -93.920904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801927382, states[0] = -93.927379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807107737, states[0] = -1.143069, states[40]= 0.004337
Saving checkpoint... 
Iteration: 811630346, states[0] = -18.382899, states[40]= 0.001924
Saving checkpoint... 
Iteration: 817381547, states[0] = -93.906968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822005933, states[0] = 32.937564, states[40]= 0.235258
Saving checkpoint... 
Iteration: 827114190, states[0] = -93.924597, states[40]= 0.000000
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Iteration: 832214215, states[0] = -93.913799, states[40]= 0.000000
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Iteration: 837125261, states[0] = -14.298902, states[40]= 0.002086
Saving checkpoint... 
Iteration: 842052236, states[0] = -93.912141, states[40]= 0.000000
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Iteration: 847342694, states[0] = -93.908377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851329559, states[0] = -93.930952, states[40]= 0.000000
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Iteration: 855973794, states[0] = -93.925090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861275963, states[0] = -93.514206, states[40]= 0.000000
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Iteration: 866059616, states[0] = -93.914028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870424698, states[0] = -93.841341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875989317, states[0] = -93.902956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880715576, states[0] = -89.135306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885251741, states[0] = -93.401795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890399376, states[0] = -93.928329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894834119, states[0] = -93.930692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899807141, states[0] = -93.909648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904702082, states[0] = -73.848591, states[40]= 0.000005
Saving checkpoint... 
Iteration: 909463463, states[0] = -93.872486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914280349, states[0] = -93.931827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918041694, states[0] = 27.097092, states[40]= 0.000400
Saving checkpoint... 
Iteration: 923197817, states[0] = -93.931082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928032718, states[0] = -93.922052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932822495, states[0] = -93.908932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937482618, states[0] = -93.903004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942700618, states[0] = -93.931124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948106299, states[0] = -0.245042, states[40]= 0.004379
Saving checkpoint... 
Iteration: 952622590, states[0] = -12.121503, states[40]= 0.002405
Saving checkpoint... 
Iteration: 956528222, states[0] = -93.922188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961300137, states[0] = -93.909756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966578544, states[0] = -93.918104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970558299, states[0] = 21.381863, states[40]= 0.000974
Saving checkpoint... 
Iteration: 974073524, states[0] = -93.917010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978779532, states[0] = -93.931651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983235936, states[0] = -93.931744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988417883, states[0] = -93.905127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992913199, states[0] = -93.905285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998713095, states[0] = -93.913366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003320681, states[0] = -93.908800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008673967, states[0] = -93.929720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014513060, states[0] = -93.898366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018589833, states[0] = 8.515457, states[40]= 0.003508
Saving checkpoint... 
Iteration: 1023770404, states[0] = -93.931619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028567250, states[0] = -93.920089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033967121, states[0] = -93.874516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038453391, states[0] = -93.865078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043780408, states[0] = -93.910334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048633958, states[0] = -21.170068, states[40]= 0.002184
Saving checkpoint... 
Iteration: 1053581125, states[0] = -93.918382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058307688, states[0] = -93.930920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063677774, states[0] = -53.437895, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1068572774, states[0] = -93.916572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072668490, states[0] = -46.469400, states[40]= 0.000432
Saving checkpoint... 
Iteration: 1077406127, states[0] = -93.821082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081786337, states[0] = -93.555020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087250990, states[0] = -93.911455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091742527, states[0] = -93.911807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096640862, states[0] = -26.252744, states[40]= 0.002749
Saving checkpoint... 
Iteration: 1100204187, states[0] = -93.930785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104959382, states[0] = -93.925046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110046647, states[0] = 25.472026, states[40]= 0.000523
Saving checkpoint... 
Iteration: 1114207671, states[0] = -93.913274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119441026, states[0] = -93.855218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124655586, states[0] = -93.915614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129923423, states[0] = -93.839348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135390313, states[0] = -93.905718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139577522, states[0] = -93.919272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144343708, states[0] = -93.907478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149386949, states[0] = -93.796483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154030033, states[0] = -93.904365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158749871, states[0] = -93.931308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163124105, states[0] = -93.924908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168211782, states[0] = -93.912934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172645304, states[0] = -93.915954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177538763, states[0] = 28.013115, states[40]= 0.000343
Saving checkpoint... 
Iteration: 1182124409, states[0] = -13.603400, states[40]= 0.002173
Saving checkpoint... 
Iteration: 1186636082, states[0] = -22.760374, states[40]= 0.002409
Saving checkpoint... 
Iteration: 1192341330, states[0] = -93.907432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197645126, states[0] = -93.927036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202504723, states[0] = -93.922612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207679682, states[0] = -54.867905, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1212720994, states[0] = -93.930875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218483311, states[0] = -93.883604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222836854, states[0] = -93.705823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226900942, states[0] = -93.905057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231477980, states[0] = -93.902310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236611231, states[0] = -93.923000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241605855, states[0] = -93.917618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244835420, states[0] = -93.907513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249112676, states[0] = -93.917271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253417819, states[0] = -93.926495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258469052, states[0] = -93.902537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262514434, states[0] = -93.921970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266612987, states[0] = -93.923161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272465751, states[0] = -93.872940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276064788, states[0] = -93.919493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280473766, states[0] = -93.923864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286085860, states[0] = -93.918642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291944304, states[0] = -93.857382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296576325, states[0] = -93.916684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301329442, states[0] = -93.929655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305635499, states[0] = -93.925782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309895268, states[0] = -93.807158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314871814, states[0] = -93.928195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319812344, states[0] = -93.908220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324364031, states[0] = -93.906167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329223411, states[0] = -92.543852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333923297, states[0] = -93.838633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338931967, states[0] = -93.925623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343980128, states[0] = -93.901911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349280554, states[0] = -93.930568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354534403, states[0] = 29.291314, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1359533624, states[0] = -93.904991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363461729, states[0] = -93.902486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368671956, states[0] = -93.928561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373897228, states[0] = -93.904769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378944251, states[0] = -93.857087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383825573, states[0] = -93.929526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389006589, states[0] = 32.426578, states[40]= 0.187732
Saving checkpoint... 
Iteration: 1393650199, states[0] = -32.991577, states[40]= 0.002073
Saving checkpoint... 
Iteration: 1397976932, states[0] = -93.901863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403120381, states[0] = -93.923752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408364651, states[0] = -93.905900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413156634, states[0] = -37.671810, states[40]= 0.001307
Saving checkpoint... 
Iteration: 1419078869, states[0] = 13.377629, states[40]= 0.002472
Saving checkpoint... 
Iteration: 1423235286, states[0] = -93.911162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428114896, states[0] = -6.069924, states[40]= 0.003655
Saving checkpoint... 
Iteration: 1432653340, states[0] = -35.269841, states[40]= 0.001684
Saving checkpoint... 
Iteration: 1436972005, states[0] = -93.901919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441497323, states[0] = -93.901050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445549273, states[0] = -93.919754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450737385, states[0] = -93.305784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455665198, states[0] = -93.927879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460220226, states[0] = -93.930146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464474978, states[0] = -93.878128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469576137, states[0] = -93.918385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474208615, states[0] = -93.912190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479025112, states[0] = 31.510299, states[40]= 0.000473
Saving checkpoint... 
Iteration: 1483748413, states[0] = -93.382543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489090380, states[0] = -93.917643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493393346, states[0] = -93.926834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498193983, states[0] = -93.912777, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.776750
 - CaMKt in component CaMK (millimolar): 0.003128
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.749619
 - nass in component intracellular_ions (millimolar): 6.749742
 - ki in component intracellular_ions (millimolar): 145.103556
 - kss in component intracellular_ions (millimolar): 145.103545
 - cansr in component intracellular_ions (millimolar): 1.842361
 - cajsr in component intracellular_ions (millimolar): 1.842096
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004054
 - hf in component INa (dimensionless): 0.859066
 - hs in component INa (dimensionless): 0.859068
 - j in component INa (dimensionless): 0.859076
 - hsp in component INa (dimensionless): 0.687587
 - jp in component INa (dimensionless): 0.859081
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698592
 - hLp in component INaL (dimensionless): 0.499745
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.968329
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.983826
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005109
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030948
 - xs1 in component IKs (dimensionless): 0.072549
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:39:57 (40257): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.935035
     * GNaL_b in INaL: 0.005177
     * Gto_b in Ito: 0.071379
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030370
     * GKs_b in IKs: 0.002017
     * GK1_b in IK1: 0.153089
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 69.243128
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022819
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498193983
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.912777 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.776750
 - CaMKt in component CaMK (millimolar): 0.003128
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.749619
 - nass in component intracellular_ions (millimolar): 6.749742
 - ki in component intracellular_ions (millimolar): 145.103556
 - kss in component intracellular_ions (millimolar): 145.103545
 - cansr in component intracellular_ions (millimolar): 1.842361
 - cajsr in component intracellular_ions (millimolar): 1.842096
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004054
 - hf in component INa (dimensionless): 0.859066
 - hs in component INa (dimensionless): 0.859068
 - j in component INa (dimensionless): 0.859076
 - hsp in component INa (dimensionless): 0.687587
 - jp in component INa (dimensionless): 0.859081
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698592
 - hLp in component INaL (dimensionless): 0.499745
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.968329
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.983826
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005109
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030948
 - xs1 in component IKs (dimensionless): 0.072549
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:43:23 (42447): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_3000-conf_684_0_r747595950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.935035
     * GNaL_b in INaL: 0.005177
     * Gto_b in Ito: 0.071379
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030370
     * GKs_b in IKs: 0.002017
     * GK1_b in IK1: 0.153089
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 69.243128
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022819
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498193983
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.912777 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.776750
 - CaMKt in component CaMK (millimolar): 0.003128
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.749619
 - nass in component intracellular_ions (millimolar): 6.749742
 - ki in component intracellular_ions (millimolar): 145.103556
 - kss in component intracellular_ions (millimolar): 145.103545
 - cansr in component intracellular_ions (millimolar): 1.842361
 - cajsr in component intracellular_ions (millimolar): 1.842096
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004054
 - hf in component INa (dimensionless): 0.859066
 - hs in component INa (dimensionless): 0.859068
 - j in component INa (dimensionless): 0.859076
 - hsp in component INa (dimensionless): 0.687587
 - jp in component INa (dimensionless): 0.859081
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698592
 - hLp in component INaL (dimensionless): 0.499745
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.968329
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.983826
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005109
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030948
 - xs1 in component IKs (dimensionless): 0.072549
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:46:57 (42471): called boinc_finish(0)

</stderr_txt>
]]>


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