𝕏

Task 55026302

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_ENDO-conf_579_1
Workunit 26128885
Created 27 Jun 2024, 18:03:35 UTC
Sent 28 Jun 2024, 2:18:24 UTC
Report deadline 1 Jul 2024, 2:18:24 UTC
Received 28 Jun 2024, 7:35:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216914
Run time 3 hours 1 min 48 sec
CPU time 2 hours 59 min 20 sec
Validate state Valid
Credit 40.33
Device peak FLOPS 1.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.80 MB
Peak swap size 1.56 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_ENDO-conf_579.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_ENDO-conf_579_1_r115151804_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_ENDO-conf_579_1_r115151804_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.529061
     * GNaL_b in INaL: 0.006406
     * Gto_b in Ito: 0.085894
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029770
     * GKs_b in IKs: 0.002123
     * GK1_b in IK1: 0.159387
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.540006
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037498
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8310782, states[0] = -86.919040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16604145, states[0] = -15.301648, states[40]= 0.001414
Saving checkpoint... 
Iteration: 24932323, states[0] = -86.929261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33258797, states[0] = -86.699781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41600833, states[0] = -10.406570, states[40]= 0.002117
Saving checkpoint... 
Iteration: 49935928, states[0] = -86.903815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58243873, states[0] = -86.635589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66548838, states[0] = 18.794592, states[40]= 0.001239
Saving checkpoint... 
Iteration: 74886683, states[0] = -86.866985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83208963, states[0] = -86.495091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91525884, states[0] = 26.908097, states[40]= 0.000713
Saving checkpoint... 
Iteration: 99857436, states[0] = -86.838314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108178864, states[0] = -85.934301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116513863, states[0] = 28.600735, states[40]= 0.012481
Saving checkpoint... 
Iteration: 124851738, states[0] = -86.830507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133188412, states[0] = -86.361243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141527966, states[0] = 26.354433, states[40]= 0.000658
Saving checkpoint... 
Iteration: 149869932, states[0] = -86.846383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158199654, states[0] = -86.445842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166536402, states[0] = 23.579620, states[40]= 0.000775
Saving checkpoint... 
Iteration: 174853569, states[0] = -86.830653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183176940, states[0] = -85.629821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191510655, states[0] = 28.333696, states[40]= 0.036840
Saving checkpoint... 
Iteration: 199850117, states[0] = -86.826761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208178549, states[0] = -85.875226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216472588, states[0] = -86.899173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224777648, states[0] = -86.713038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233095110, states[0] = -4.579948, states[40]= 0.003110
Saving checkpoint... 
Iteration: 241433030, states[0] = -86.884507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249705121, states[0] = -86.470788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258034585, states[0] = 24.225601, states[40]= 0.000729
Saving checkpoint... 
Iteration: 266370007, states[0] = -86.844953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274695198, states[0] = -86.419896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283021871, states[0] = 27.878705, states[40]= 0.001233
Saving checkpoint... 
Iteration: 291344130, states[0] = -86.819651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299685905, states[0] = -86.312796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308022041, states[0] = 27.845093, states[40]= 0.001191
Saving checkpoint... 
Iteration: 316254945, states[0] = -86.654528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324541332, states[0] = 21.773718, states[40]= 0.000936
Saving checkpoint... 
Iteration: 332836247, states[0] = -86.810316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341169478, states[0] = -82.246123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349508657, states[0] = 28.105430, states[40]= 0.072830
Saving checkpoint... 
Iteration: 357845656, states[0] = -86.820973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366131078, states[0] = -39.458560, states[40]= 0.000308
Saving checkpoint... 
Iteration: 374467600, states[0] = -86.896715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382797263, states[0] = -86.751935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391100330, states[0] = -9.186052, states[40]= 0.002358
Saving checkpoint... 
Iteration: 399442407, states[0] = -86.887613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407709353, states[0] = -86.488855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416044446, states[0] = 20.594270, states[40]= 0.001060
Saving checkpoint... 
Iteration: 424369805, states[0] = -86.843937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432715697, states[0] = -86.515894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441057831, states[0] = 15.340875, states[40]= 0.001785
Saving checkpoint... 
Iteration: 449379300, states[0] = -86.851495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457694252, states[0] = -86.412814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465979834, states[0] = -86.899819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474306620, states[0] = -86.767688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482529284, states[0] = 25.969678, states[40]= 0.000652
Saving checkpoint... 
Iteration: 490872637, states[0] = -86.845966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499182178, states[0] = -86.178538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507483668, states[0] = -86.900634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515805235, states[0] = -86.765173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524118316, states[0] = -27.046163, states[40]= 0.000897
Saving checkpoint... 
Iteration: 532457462, states[0] = -86.892573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540795336, states[0] = -86.747566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549124297, states[0] = -32.854265, states[40]= 0.000629
Saving checkpoint... 
Iteration: 557433098, states[0] = -86.882851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565777159, states[0] = -86.710056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574102099, states[0] = -10.886486, states[40]= 0.002061
Saving checkpoint... 
Iteration: 582421327, states[0] = -86.877154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590756339, states[0] = -86.657068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599089890, states[0] = -0.674098, states[40]= 0.003460
Saving checkpoint... 
Iteration: 607406164, states[0] = -86.868793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615734790, states[0] = -86.588559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624060878, states[0] = 14.094927, states[40]= 0.001989
Saving checkpoint... 
Iteration: 632400792, states[0] = -86.865429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640744330, states[0] = -86.620565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649072210, states[0] = 9.143816, states[40]= 0.002791
Saving checkpoint... 
Iteration: 657409184, states[0] = -86.870279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665738941, states[0] = -86.602657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674017475, states[0] = 28.516968, states[40]= 0.003900
Saving checkpoint... 
Iteration: 682354153, states[0] = -86.828174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690690725, states[0] = -86.383305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699011532, states[0] = 28.439500, states[40]= 0.027341
Saving checkpoint... 
Iteration: 707333478, states[0] = -86.804998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715668311, states[0] = -81.203592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723873594, states[0] = -86.845555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732155957, states[0] = -65.815794, states[40]= 0.000006
Saving checkpoint... 
Iteration: 740483135, states[0] = -86.899301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748815493, states[0] = -86.780228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757143822, states[0] = -52.317777, states[40]= 0.000051
Saving checkpoint... 
Iteration: 765476125, states[0] = -86.897250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773796398, states[0] = -86.748326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782134048, states[0] = -42.385243, states[40]= 0.000211
Saving checkpoint... 
Iteration: 790481259, states[0] = -86.898544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798823741, states[0] = -86.791813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807113071, states[0] = -21.897108, states[40]= 0.000999
Saving checkpoint... 
Iteration: 815457956, states[0] = -86.891293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823741542, states[0] = -86.610533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832068690, states[0] = 10.750662, states[40]= 0.002542
Saving checkpoint... 
Iteration: 840389407, states[0] = -86.856889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848704551, states[0] = -86.464967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857044384, states[0] = 20.618714, states[40]= 0.001057
Saving checkpoint... 
Iteration: 865351426, states[0] = -86.824469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873689233, states[0] = -86.365900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882034108, states[0] = 24.392308, states[40]= 0.000718
Saving checkpoint... 
Iteration: 890340193, states[0] = -86.812094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898672312, states[0] = -84.110378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906985658, states[0] = -86.899105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915320708, states[0] = -86.786977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923649637, states[0] = -58.515120, states[40]= 0.000019
Saving checkpoint... 
Iteration: 931985743, states[0] = -86.898999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940323756, states[0] = -86.791104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948643059, states[0] = -51.522827, states[40]= 0.000057
Saving checkpoint... 
Iteration: 956971979, states[0] = -86.895062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965300699, states[0] = -86.755071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973339409, states[0] = -86.810756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981692663, states[0] = -86.398622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990054214, states[0] = 16.791359, states[40]= 0.001560
Saving checkpoint... 
Iteration: 998389807, states[0] = -86.856355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006699575, states[0] = -86.440245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015018036, states[0] = 28.464505, states[40]= 0.003293
Saving checkpoint... 
Iteration: 1023344137, states[0] = -86.815873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031681897, states[0] = -86.159808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040009289, states[0] = 28.167235, states[40]= 0.058688
Saving checkpoint... 
Iteration: 1048315369, states[0] = -86.778496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056665836, states[0] = -78.526519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065009101, states[0] = 28.146944, states[40]= 0.062579
Saving checkpoint... 
Iteration: 1073332565, states[0] = -86.801974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081670164, states[0] = -82.770464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090009974, states[0] = 28.249769, states[40]= 0.046455
Saving checkpoint... 
Iteration: 1098345258, states[0] = -86.816723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106691253, states[0] = -86.386084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115036444, states[0] = 23.571113, states[40]= 0.000777
Saving checkpoint... 
Iteration: 1123378416, states[0] = -86.847347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131725228, states[0] = -86.550534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140079775, states[0] = 5.385961, states[40]= 0.003261
Saving checkpoint... 
Iteration: 1148402439, states[0] = -86.863792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156752768, states[0] = -86.643813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165052696, states[0] = 17.392319, states[40]= 0.001471
Saving checkpoint... 
Iteration: 1173388849, states[0] = -86.854789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181727135, states[0] = -86.557568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190075026, states[0] = 7.800909, states[40]= 0.002980
Saving checkpoint... 
Iteration: 1198417304, states[0] = -86.871932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206721604, states[0] = -86.535933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215032982, states[0] = 24.777300, states[40]= 0.000694
Saving checkpoint... 
Iteration: 1223386525, states[0] = -86.852888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231734014, states[0] = -86.582588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240088482, states[0] = 0.272872, states[40]= 0.003487
Saving checkpoint... 
Iteration: 1248416201, states[0] = -86.871095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256773067, states[0] = -86.696993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265120393, states[0] = -29.060883, states[40]= 0.000823
Saving checkpoint... 
Iteration: 1273455306, states[0] = -86.888020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281810654, states[0] = -86.770027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290135235, states[0] = -43.562622, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1298475057, states[0] = -86.894214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306767365, states[0] = -86.682808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315080443, states[0] = 5.029365, states[40]= 0.003294
Saving checkpoint... 
Iteration: 1323368404, states[0] = -86.838115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331678827, states[0] = -85.899903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340010771, states[0] = 28.350733, states[40]= 0.035407
Saving checkpoint... 
Iteration: 1348343902, states[0] = -86.813939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356681446, states[0] = -86.130684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365012302, states[0] = 28.517104, states[40]= 0.021065
Saving checkpoint... 
Iteration: 1373357361, states[0] = -86.827771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381698162, states[0] = -86.430937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390047214, states[0] = 19.532350, states[40]= 0.001184
Saving checkpoint... 
Iteration: 1398381291, states[0] = -86.848139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406723861, states[0] = -86.543785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415068740, states[0] = 10.729734, states[40]= 0.002545
Saving checkpoint... 
Iteration: 1423403514, states[0] = -86.863031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431750627, states[0] = -86.636011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440096639, states[0] = -5.848148, states[40]= 0.002926
Saving checkpoint... 
Iteration: 1449074123, states[0] = 8.239025, states[40]= 0.002920
Saving checkpoint... 
Iteration: 1457251810, states[0] = -86.639415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465471687, states[0] = -86.892370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473697448, states[0] = -86.426598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481931774, states[0] = -86.877517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490356129, states[0] = -86.825971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498829238, states[0] = -86.795541, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.775360
 - CaMKt in component CaMK (millimolar): 0.012596
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.648491
 - nass in component intracellular_ions (millimolar): 6.648584
 - ki in component intracellular_ions (millimolar): 145.229377
 - kss in component intracellular_ions (millimolar): 145.229355
 - cansr in component intracellular_ions (millimolar): 1.641875
 - cajsr in component intracellular_ions (millimolar): 1.597358
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.008205
 - hf in component INa (dimensionless): 0.658622
 - hs in component INa (dimensionless): 0.658601
 - j in component INa (dimensionless): 0.658481
 - hsp in component INa (dimensionless): 0.410506
 - jp in component INa (dimensionless): 0.658398
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.460780
 - hLp in component INaL (dimensionless): 0.232572
 - a in component Ito (dimensionless): 0.001078
 - iF in component Ito (dimensionless): 0.999459
 - iS in component Ito (dimensionless): 0.563153
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999459
 - iSp in component Ito (dimensionless): 0.611478
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.911929
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999819
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002955
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.467034
 - xs1 in component IKs (dimensionless): 0.278217
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997037
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:34:43 (4968): called boinc_finish(0)

</stderr_txt>
]]>


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