𝕏

Task 55024166

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_776_1
Workunit 26127818
Created 27 Jun 2024, 18:02:36 UTC
Sent 28 Jun 2024, 2:12:16 UTC
Report deadline 1 Jul 2024, 2:12:16 UTC
Received 28 Jun 2024, 10:11:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 17 min 23 sec
CPU time 2 hours 12 min 6 sec
Validate state Valid
Credit 41.86
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.42 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_776.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_776_1_r2096395958_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_776_1_r2096395958_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.938809
     * GNaL_b in INaL: 0.005199
     * Gto_b in Ito: 0.079092
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031778
     * GKs_b in IKs: 0.000105
     * GK1_b in IK1: 0.162305
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.196270
     * GKb_b in IKb: 0.003692
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020784
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11233650, states[0] = -94.692381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22524921, states[0] = 26.183268, states[40]= 0.002087
Saving checkpoint... 
Iteration: 33782761, states[0] = -94.715337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45066894, states[0] = 11.018382, states[40]= 0.004387
Saving checkpoint... 
Iteration: 56164066, states[0] = -76.365657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67383069, states[0] = -94.816665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78578940, states[0] = 5.226870, states[40]= 0.004936
Saving checkpoint... 
Iteration: 89762542, states[0] = -94.648239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100947826, states[0] = -94.844084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112141793, states[0] = -49.527507, states[40]= 0.000108
Saving checkpoint... 
Iteration: 123352758, states[0] = -94.786234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134570924, states[0] = 9.401077, states[40]= 0.004652
Saving checkpoint... 
Iteration: 145765635, states[0] = -94.652393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156912438, states[0] = -94.826697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168100866, states[0] = -10.333029, states[40]= 0.002689
Saving checkpoint... 
Iteration: 179299392, states[0] = -94.718439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190498685, states[0] = -94.855116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201617003, states[0] = -25.536168, states[40]= 0.001315
Saving checkpoint... 
Iteration: 212679751, states[0] = -93.397161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223860677, states[0] = -94.791605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235064429, states[0] = 12.377422, states[40]= 0.004245
Saving checkpoint... 
Iteration: 246278244, states[0] = -94.679132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257474570, states[0] = -94.849041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268657888, states[0] = -66.832763, states[40]= 0.000007
Saving checkpoint... 
Iteration: 279902171, states[0] = -94.820270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291164390, states[0] = -75.648017, states[40]= 0.000002
Saving checkpoint... 
Iteration: 301258726, states[0] = -94.634147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310326325, states[0] = -94.755879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318946601, states[0] = -94.840139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329862305, states[0] = -94.792516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340943826, states[0] = -94.839051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352135464, states[0] = -43.022001, states[40]= 0.000274
Saving checkpoint... 
Iteration: 363361303, states[0] = -94.791539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374218328, states[0] = -94.505599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385194355, states[0] = -94.393889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396384902, states[0] = -94.809238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407570145, states[0] = 9.789602, states[40]= 0.004612
Saving checkpoint... 
Iteration: 418692528, states[0] = -94.376937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429904074, states[0] = -94.820743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441103967, states[0] = -13.214169, states[40]= 0.002099
Saving checkpoint... 
Iteration: 452296856, states[0] = -94.712935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463471439, states[0] = -94.847387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474656283, states[0] = -64.911330, states[40]= 0.000009
Saving checkpoint... 
Iteration: 485828690, states[0] = -94.758065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497030379, states[0] = 25.035868, states[40]= 0.001860
Saving checkpoint... 
Iteration: 508239877, states[0] = -94.580094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519443990, states[0] = -94.838431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530490361, states[0] = -94.851848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541665812, states[0] = -77.845673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552879085, states[0] = -94.804640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564073203, states[0] = 8.315712, states[40]= 0.004767
Saving checkpoint... 
Iteration: 575278404, states[0] = -94.678166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586507013, states[0] = 29.443296, states[40]= 0.131563
Saving checkpoint... 
Iteration: 597706722, states[0] = -94.457823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608912604, states[0] = -94.824554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620036512, states[0] = 23.063583, states[40]= 0.002141
Saving checkpoint... 
Iteration: 631251837, states[0] = -94.614655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642426917, states[0] = -94.831139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653630290, states[0] = -37.989742, states[40]= 0.000521
Saving checkpoint... 
Iteration: 664848094, states[0] = -94.778354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676059571, states[0] = 14.438628, states[40]= 0.003877
Saving checkpoint... 
Iteration: 687153610, states[0] = -61.860656, states[40]= 0.000015
Saving checkpoint... 
Iteration: 698365742, states[0] = -94.793954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709578142, states[0] = 5.777409, states[40]= 0.004934
Saving checkpoint... 
Iteration: 720808545, states[0] = -94.730343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732036990, states[0] = 22.901635, states[40]= 0.002169
Saving checkpoint... 
Iteration: 743214203, states[0] = -94.488033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754397550, states[0] = -94.815804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765267074, states[0] = -94.652679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776439627, states[0] = -94.835824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787635987, states[0] = -43.537480, states[40]= 0.000255
Saving checkpoint... 
Iteration: 798849357, states[0] = -94.779068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810064310, states[0] = 12.431008, states[40]= 0.004237
Saving checkpoint... 
Iteration: 821285045, states[0] = -94.690373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832521483, states[0] = 27.317936, states[40]= 0.002425
Saving checkpoint... 
Iteration: 843588434, states[0] = -0.369406, states[40]= 0.004730
Saving checkpoint... 
Iteration: 854789594, states[0] = -94.698715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865969029, states[0] = -94.845188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877165373, states[0] = -77.151375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888388687, states[0] = -94.809848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899612438, states[0] = -21.264820, states[40]= 0.001362
Saving checkpoint... 
Iteration: 910839488, states[0] = -94.768640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922076702, states[0] = 6.539983, states[40]= 0.004898
Saving checkpoint... 
Iteration: 933329248, states[0] = -94.757025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944589268, states[0] = -0.936670, states[40]= 0.004662
Saving checkpoint... 
Iteration: 955726927, states[0] = -94.535179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966978203, states[0] = -94.847273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978240525, states[0] = -94.580303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989418729, states[0] = -94.826102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000556586, states[0] = 15.651621, states[40]= 0.003636
Saving checkpoint... 
Iteration: 1011770440, states[0] = -94.659416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023009727, states[0] = 28.537325, states[40]= 0.053387
Saving checkpoint... 
Iteration: 1034270233, states[0] = -94.658865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045494628, states[0] = -94.850833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056723833, states[0] = -94.523628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067984801, states[0] = -94.848522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079208133, states[0] = -94.461934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090462716, states[0] = -94.842495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101713956, states[0] = -94.485666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112930865, states[0] = -94.831039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124182990, states[0] = -93.985585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135418592, states[0] = -94.825482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146662608, states[0] = -73.020943, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157575773, states[0] = 7.022101, states[40]= 0.004868
Saving checkpoint... 
Iteration: 1168910549, states[0] = -94.821381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179935961, states[0] = -94.832863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191160268, states[0] = -69.828281, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1202383349, states[0] = -94.805129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213615192, states[0] = -23.840103, states[40]= 0.001338
Saving checkpoint... 
Iteration: 1224826665, states[0] = -94.752805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236057096, states[0] = 15.447407, states[40]= 0.003678
Saving checkpoint... 
Iteration: 1247291894, states[0] = -94.701342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258518635, states[0] = 27.815069, states[40]= 0.003907
Saving checkpoint... 
Iteration: 1269773954, states[0] = -94.666150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280926190, states[0] = -94.828398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292154307, states[0] = -62.636621, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1303397016, states[0] = -94.813404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314480538, states[0] = -94.846546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325639530, states[0] = -47.085354, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1336846614, states[0] = -94.774343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348052497, states[0] = 17.257341, states[40]= 0.003299
Saving checkpoint... 
Iteration: 1359294695, states[0] = -94.705802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370540257, states[0] = 21.770950, states[40]= 0.002371
Saving checkpoint... 
Iteration: 1381768779, states[0] = -94.654245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393000889, states[0] = 46.062648, states[40]= 0.110518
Saving checkpoint... 
Iteration: 1404234410, states[0] = -94.559103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415469630, states[0] = -94.843273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426688746, states[0] = -94.311816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437875463, states[0] = -94.798661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449118656, states[0] = -27.059487, states[40]= 0.001271
Saving checkpoint... 
Iteration: 1460361968, states[0] = -94.787930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471455785, states[0] = -94.838883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482660165, states[0] = -69.690716, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1493883878, states[0] = -94.804380, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.726105
 - CaMKt in component CaMK (millimolar): 0.012871
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.648577
 - nass in component intracellular_ions (millimolar): 6.648674
 - ki in component intracellular_ions (millimolar): 145.232700
 - kss in component intracellular_ions (millimolar): 145.232680
 - cansr in component intracellular_ions (millimolar): 1.672763
 - cajsr in component intracellular_ions (millimolar): 1.630648
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003683
 - hf in component INa (dimensionless): 0.876918
 - hs in component INa (dimensionless): 0.876909
 - j in component INa (dimensionless): 0.876856
 - hsp in component INa (dimensionless): 0.720025
 - jp in component INa (dimensionless): 0.876820
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.701563
 - hLp in component INaL (dimensionless): 0.436607
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.606836
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.676676
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.912502
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999816
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003127
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.374222
 - xs1 in component IKs (dimensionless): 0.274129
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997383
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:06:50 (62157): called boinc_finish(0)

</stderr_txt>
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