𝕏

Task 55023772

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_276_0
Workunit 26127622
Created 27 Jun 2024, 18:02:26 UTC
Sent 28 Jun 2024, 2:09:27 UTC
Report deadline 1 Jul 2024, 2:09:27 UTC
Received 28 Jun 2024, 10:33:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 202888
Run time 1 hours 58 min 7 sec
CPU time 40 min 52 sec
Validate state Valid
Credit 40.73
Device peak FLOPS 3.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.86 MB
Peak swap size 6.39 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_276_0_r1020284662_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_276_0_r1020284662_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.331028
     * GNaL_b in INaL: 0.006450
     * Gto_b in Ito: 0.076240
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029976
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.157307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.518163
     * GKb_b in IKb: 0.003846
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041223
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8663761, states[0] = -87.879703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18143595, states[0] = -87.808269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28832115, states[0] = 39.302800, states[40]= 0.065143
Saving checkpoint... 
Iteration: 36828512, states[0] = -87.870863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44233356, states[0] = -27.366875, states[40]= 0.000675
Saving checkpoint... 
Iteration: 52426572, states[0] = -65.350510, states[40]= 0.000004
Saving checkpoint... 
Iteration: 61193936, states[0] = 11.996772, states[40]= 0.007737
Saving checkpoint... 
Iteration: 70230060, states[0] = -26.627817, states[40]= 0.000723
Saving checkpoint... 
Iteration: 78376956, states[0] = -2.240133, states[40]= 0.005491
Saving checkpoint... 
Iteration: 86801144, states[0] = -87.808435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96026981, states[0] = 9.860011, states[40]= 0.007453
Saving checkpoint... 
Iteration: 104788848, states[0] = -87.761900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113187285, states[0] = 12.859607, states[40]= 0.007880
Saving checkpoint... 
Iteration: 122329769, states[0] = 24.101875, states[40]= 0.059608
Saving checkpoint... 
Iteration: 130345380, states[0] = 16.813792, states[40]= 0.008957
Saving checkpoint... 
Iteration: 138211439, states[0] = -10.696471, states[40]= 0.003076
Saving checkpoint... 
Iteration: 146758567, states[0] = -79.161542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154545912, states[0] = -14.418663, states[40]= 0.002162
Saving checkpoint... 
Iteration: 163035452, states[0] = -2.609865, states[40]= 0.005403
Saving checkpoint... 
Iteration: 172062677, states[0] = -39.418184, states[40]= 0.000179
Saving checkpoint... 
Iteration: 181488306, states[0] = 25.876420, states[40]= 0.093104
Saving checkpoint... 
Iteration: 190548085, states[0] = -22.329821, states[40]= 0.001035
Saving checkpoint... 
Iteration: 198358068, states[0] = 3.942319, states[40]= 0.006700
Saving checkpoint... 
Iteration: 208111722, states[0] = -87.762443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216459834, states[0] = -87.829243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224293763, states[0] = -87.834067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233891288, states[0] = -41.369714, states[40]= 0.000137
Saving checkpoint... 
Iteration: 243423713, states[0] = -86.531842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251208259, states[0] = -21.748835, states[40]= 0.001087
Saving checkpoint... 
Iteration: 259826987, states[0] = 19.495855, states[40]= 0.011448
Saving checkpoint... 
Iteration: 267376624, states[0] = -26.252853, states[40]= 0.000747
Saving checkpoint... 
Iteration: 275640864, states[0] = 38.968096, states[40]= 0.077308
Saving checkpoint... 
Iteration: 283434050, states[0] = -87.737104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291986318, states[0] = 21.231843, states[40]= 0.017185
Saving checkpoint... 
Iteration: 300496237, states[0] = 16.155713, states[40]= 0.008684
Saving checkpoint... 
Iteration: 308182437, states[0] = 2.255201, states[40]= 0.006435
Saving checkpoint... 
Iteration: 317011018, states[0] = 5.407228, states[40]= 0.006904
Saving checkpoint... 
Iteration: 325673035, states[0] = 8.207121, states[40]= 0.007254
Saving checkpoint... 
Iteration: 333437035, states[0] = -87.785490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341722387, states[0] = -53.045820, states[40]= 0.000025
Saving checkpoint... 
Iteration: 350102075, states[0] = -87.785626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358147034, states[0] = 20.967174, states[40]= 0.015803
Saving checkpoint... 
Iteration: 366504022, states[0] = 6.950679, states[40]= 0.007101
Saving checkpoint... 
Iteration: 375120762, states[0] = -87.862359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382748578, states[0] = -87.484815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390784017, states[0] = -87.856624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399563887, states[0] = -74.714563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407595644, states[0] = -87.782369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416618106, states[0] = -87.866793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422641049, states[0] = 20.779397, states[40]= 0.014971
Saving checkpoint... 
Iteration: 427141281, states[0] = 20.498196, states[40]= 0.013918
Saving checkpoint... 
Iteration: 431167709, states[0] = 4.272001, states[40]= 0.006748
Saving checkpoint... 
Iteration: 439790133, states[0] = 36.542122, states[40]= 0.013620
Saving checkpoint... 
Iteration: 448714880, states[0] = -57.585006, states[40]= 0.000012
Saving checkpoint... 
Iteration: 458430090, states[0] = -87.808386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466857626, states[0] = -27.540764, states[40]= 0.000669
Saving checkpoint... 
Iteration: 476079043, states[0] = -87.709332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484101557, states[0] = -87.835268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491192631, states[0] = -33.040560, states[40]= 0.000390
Saving checkpoint... 
Iteration: 499430164, states[0] = -87.823979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508311225, states[0] = 14.778089, states[40]= 0.008268
Saving checkpoint... 
Iteration: 517069903, states[0] = -87.570681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526195113, states[0] = -41.002184, states[40]= 0.000144
Saving checkpoint... 
Iteration: 534444068, states[0] = -87.879452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541806525, states[0] = 15.550329, states[40]= 0.008480
Saving checkpoint... 
Iteration: 549608962, states[0] = -87.878764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558452016, states[0] = 24.618115, states[40]= 0.070515
Saving checkpoint... 
Iteration: 567357862, states[0] = -41.267790, states[40]= 0.000139
Saving checkpoint... 
Iteration: 576074048, states[0] = -87.756643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585193770, states[0] = -47.152118, states[40]= 0.000060
Saving checkpoint... 
Iteration: 593948792, states[0] = 24.394493, states[40]= 0.065902
Saving checkpoint... 
Iteration: 602602164, states[0] = -87.874428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611135656, states[0] = 13.962941, states[40]= 0.008085
Saving checkpoint... 
Iteration: 618997067, states[0] = -11.203271, states[40]= 0.002939
Saving checkpoint... 
Iteration: 628528254, states[0] = -54.759678, states[40]= 0.000019
Saving checkpoint... 
Iteration: 636593780, states[0] = -87.859517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644765303, states[0] = -87.876334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654296631, states[0] = 14.773942, states[40]= 0.008267
Saving checkpoint... 
Iteration: 662695471, states[0] = -60.513226, states[40]= 0.000008
Saving checkpoint... 
Iteration: 671556542, states[0] = -87.649352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680891594, states[0] = -87.704781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689821835, states[0] = -9.277939, states[40]= 0.003480
Saving checkpoint... 
Iteration: 697603528, states[0] = 25.690247, states[40]= 0.090184
Saving checkpoint... 
Iteration: 704793033, states[0] = 13.917365, states[40]= 0.008076
Saving checkpoint... 
Iteration: 713585243, states[0] = -87.856762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721174948, states[0] = -40.114534, states[40]= 0.000163
Saving checkpoint... 
Iteration: 729080817, states[0] = -87.847553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738466094, states[0] = 7.483740, states[40]= 0.007166
Saving checkpoint... 
Iteration: 747646992, states[0] = -6.323755, states[40]= 0.004359
Saving checkpoint... 
Iteration: 756143916, states[0] = -3.794895, states[40]= 0.005088
Saving checkpoint... 
Iteration: 764093720, states[0] = 32.012554, states[40]= 0.124900
Saving checkpoint... 
Iteration: 772024131, states[0] = -70.447446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 781188006, states[0] = -67.337058, states[40]= 0.000003
Saving checkpoint... 
Iteration: 790908693, states[0] = -87.849808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799281938, states[0] = 14.886676, states[40]= 0.008295
Saving checkpoint... 
Iteration: 807894514, states[0] = -87.805469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815319108, states[0] = -22.565908, states[40]= 0.001015
Saving checkpoint... 
Iteration: 823843992, states[0] = -57.528950, states[40]= 0.000012
Saving checkpoint... 
Iteration: 832312564, states[0] = -15.927876, states[40]= 0.001864
Saving checkpoint... 
Iteration: 839807131, states[0] = -9.655757, states[40]= 0.003370
Saving checkpoint... 
Iteration: 848936745, states[0] = 18.556497, states[40]= 0.010177
Saving checkpoint... 
Iteration: 857385328, states[0] = -87.787805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866403701, states[0] = -87.857801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874435211, states[0] = 18.057789, states[40]= 0.009723
Saving checkpoint... 
Iteration: 883303115, states[0] = -10.087597, states[40]= 0.003247
Saving checkpoint... 
Iteration: 891426572, states[0] = 21.151640, states[40]= 0.016736
Saving checkpoint... 
Iteration: 899909055, states[0] = -87.883180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907793009, states[0] = -1.302893, states[40]= 0.005722
Saving checkpoint... 
Iteration: 916273480, states[0] = 12.946590, states[40]= 0.007895
Saving checkpoint... 
Iteration: 923881495, states[0] = -87.799631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933605059, states[0] = 12.959564, states[40]= 0.007898
Saving checkpoint... 
Iteration: 942775402, states[0] = 9.996036, states[40]= 0.007473
Saving checkpoint... 
Iteration: 948860887, states[0] = -87.606848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957118492, states[0] = 1.422843, states[40]= 0.006288
Saving checkpoint... 
Iteration: 966074579, states[0] = 29.001893, states[40]= 0.122343
Saving checkpoint... 
Iteration: 974196018, states[0] = -87.710409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981831945, states[0] = -63.121064, states[40]= 0.000005
Saving checkpoint... 
Iteration: 989909596, states[0] = 24.142192, states[40]= 0.060539
Saving checkpoint... 
Iteration: 998276776, states[0] = 4.972671, states[40]= 0.006846
Saving checkpoint... 
Iteration: 1007070296, states[0] = 29.438215, states[40]= 0.123948
Saving checkpoint... 
Iteration: 1016026525, states[0] = -87.726879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024751476, states[0] = 19.041107, states[40]= 0.010748
Saving checkpoint... 
Iteration: 1032749331, states[0] = 19.656191, states[40]= 0.011743
Saving checkpoint... 
Iteration: 1041356966, states[0] = -87.722879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049794216, states[0] = -20.594782, states[40]= 0.001202
Saving checkpoint... 
Iteration: 1058853583, states[0] = -87.700890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067833272, states[0] = -79.410051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076868872, states[0] = -87.810112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084891643, states[0] = -70.276823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093123872, states[0] = -21.496591, states[40]= 0.001111
Saving checkpoint... 
Iteration: 1101850584, states[0] = -87.719035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110136821, states[0] = -41.146550, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1119048860, states[0] = -87.869000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127502818, states[0] = -86.789693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136583337, states[0] = 13.824473, states[40]= 0.008057
Saving checkpoint... 
Iteration: 1144208171, states[0] = -87.854172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152735849, states[0] = 20.300928, states[40]= 0.013294
Saving checkpoint... 
Iteration: 1161751038, states[0] = 11.617550, states[40]= 0.007689
Saving checkpoint... 
Iteration: 1169495292, states[0] = -85.366248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178766453, states[0] = -1.844265, states[40]= 0.005593
Saving checkpoint... 
Iteration: 1186739406, states[0] = 16.981290, states[40]= 0.009039
Saving checkpoint... 
Iteration: 1194439162, states[0] = -10.738408, states[40]= 0.003065
Saving checkpoint... 
Iteration: 1203099924, states[0] = -4.576765, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1211570952, states[0] = 16.610174, states[40]= 0.008865
Saving checkpoint... 
Iteration: 1219809266, states[0] = -64.871789, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1229871604, states[0] = -87.870230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238612482, states[0] = -25.794282, states[40]= 0.000776
Saving checkpoint... 
Iteration: 1247917148, states[0] = 5.997726, states[40]= 0.006981
Saving checkpoint... 
Iteration: 1255739858, states[0] = 12.742813, states[40]= 0.007861
Saving checkpoint... 
Iteration: 1265126083, states[0] = -47.577389, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1275505003, states[0] = -87.761298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283951816, states[0] = -39.873331, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1291600286, states[0] = -16.371000, states[40]= 0.001785
Saving checkpoint... 
Iteration: 1299083159, states[0] = 2.408681, states[40]= 0.006460
Saving checkpoint... 
Iteration: 1307902646, states[0] = 11.901973, states[40]= 0.007730
Saving checkpoint... 
Iteration: 1316696928, states[0] = -87.872073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325145609, states[0] = -84.828243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333145186, states[0] = -85.098693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341542421, states[0] = 23.448468, states[40]= 0.045834
Saving checkpoint... 
Iteration: 1349701909, states[0] = 31.710209, states[40]= 0.125434
Saving checkpoint... 
Iteration: 1358402423, states[0] = 8.674851, states[40]= 0.007310
Saving checkpoint... 
Iteration: 1366690091, states[0] = -87.866613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374949322, states[0] = -48.793546, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1383282548, states[0] = -49.791731, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1391003452, states[0] = -87.807035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398309557, states[0] = -86.910870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404403507, states[0] = 4.434093, states[40]= 0.006771
Saving checkpoint... 
Iteration: 1412891438, states[0] = 12.349745, states[40]= 0.007798
Saving checkpoint... 
Iteration: 1422270096, states[0] = -38.245892, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1430917389, states[0] = -13.238034, states[40]= 0.002425
Saving checkpoint... 
Iteration: 1438773803, states[0] = -45.424665, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1446276569, states[0] = -50.233005, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1456246717, states[0] = -11.269052, states[40]= 0.002921
Saving checkpoint... 
Iteration: 1466264640, states[0] = -36.841667, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1474330211, states[0] = -87.813631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482505779, states[0] = -87.847555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491145913, states[0] = -87.728730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499097028, states[0] = -39.952290, states[40]= 0.000166
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.760594
 - CaMKt in component CaMK (millimolar): 0.043042
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.017299
 - nass in component intracellular_ions (millimolar): 7.017446
 - ki in component intracellular_ions (millimolar): 144.903180
 - kss in component intracellular_ions (millimolar): 144.903148
 - cansr in component intracellular_ions (millimolar): 1.620132
 - cajsr in component intracellular_ions (millimolar): 1.185218
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007431
 - hf in component INa (dimensionless): 0.694039
 - hs in component INa (dimensionless): 0.693794
 - j in component INa (dimensionless): 0.680577
 - hsp in component INa (dimensionless): 0.449033
 - jp in component INa (dimensionless): 0.650106
 - mL in component INaL (dimensionless): 0.000192
 - hL in component INaL (dimensionless): 0.282033
 - hLp in component INaL (dimensionless): 0.129746
 - a in component Ito (dimensionless): 0.001009
 - iF in component Ito (dimensionless): 0.999544
 - iS in component Ito (dimensionless): 0.168822
 - ap in component Ito (dimensionless): 0.000514
 - iFp in component Ito (dimensionless): 0.999544
 - iSp in component Ito (dimensionless): 0.202810
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.791646
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.963608
 - jca in component ICaL (dimensionless): 0.943971
 - ffp in component ICaL (dimensionless): 0.999808
 - fcafp in component ICaL (dimensionless): 0.999989
 - nca in component ICaL (dimensionless): 0.009498
 - xrf in component IKr (dimensionless): 0.034362
 - xrs in component IKr (dimensionless): 0.794239
 - xs1 in component IKs (dimensionless): 0.471400
 - xs2 in component IKs (dimensionless): 0.001487
 - xk1 in component IK1 (dimensionless): 0.996796
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:32:53 (19060): called boinc_finish(0)

</stderr_txt>
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