𝕏

Task 55023768

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_1000-conf_976_0
Workunit 26127620
Created 27 Jun 2024, 18:02:26 UTC
Sent 28 Jun 2024, 2:09:27 UTC
Report deadline 1 Jul 2024, 2:09:27 UTC
Received 28 Jun 2024, 5:31:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 202888
Run time 1 hours 49 min 39 sec
CPU time 40 min 48 sec
Validate state Valid
Credit 40.71
Device peak FLOPS 3.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.86 MB
Peak swap size 6.39 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_1000-conf_976.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_1000-conf_976_0_r21602309_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_1000-conf_976_0_r21602309_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.902311
     * GNaL_b in INaL: 0.006828
     * Gto_b in Ito: 0.094651
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029907
     * GKs_b in IKs: 0.001858
     * GK1_b in IK1: 0.178494
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 72.427588
     * GKb_b in IKb: 0.003837
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050371
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8636083, states[0] = -61.315030, states[40]= 0.000004
Saving checkpoint... 
Iteration: 17327867, states[0] = -87.116507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26378816, states[0] = -87.106540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34477362, states[0] = -87.108327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42428941, states[0] = -87.085392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52404927, states[0] = -87.066093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62143002, states[0] = -60.630651, states[40]= 0.000004
Saving checkpoint... 
Iteration: 71186647, states[0] = -86.850749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79845399, states[0] = -87.023591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89063343, states[0] = 7.306608, states[40]= 0.004557
Saving checkpoint... 
Iteration: 98605769, states[0] = -21.629030, states[40]= 0.000824
Saving checkpoint... 
Iteration: 107799790, states[0] = -86.986979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116248725, states[0] = -86.935332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125067946, states[0] = 5.484945, states[40]= 0.004483
Saving checkpoint... 
Iteration: 134153155, states[0] = -72.689013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143137365, states[0] = -52.246243, states[40]= 0.000018
Saving checkpoint... 
Iteration: 152203138, states[0] = -86.862314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161400643, states[0] = -87.029393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170746815, states[0] = -86.928498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179975266, states[0] = -87.043764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189107964, states[0] = -23.245014, states[40]= 0.000747
Saving checkpoint... 
Iteration: 198485972, states[0] = -87.044802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207539492, states[0] = 16.429440, states[40]= 0.004804
Saving checkpoint... 
Iteration: 216205512, states[0] = -86.864827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226101544, states[0] = -17.212777, states[40]= 0.001137
Saving checkpoint... 
Iteration: 234362479, states[0] = -87.015156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244131235, states[0] = -45.577815, states[40]= 0.000051
Saving checkpoint... 
Iteration: 252786841, states[0] = -86.969595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260827566, states[0] = -86.998202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268720778, states[0] = -86.890074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277396466, states[0] = -87.026748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286148066, states[0] = -64.947253, states[40]= 0.000002
Saving checkpoint... 
Iteration: 295618398, states[0] = -33.007481, states[40]= 0.000312
Saving checkpoint... 
Iteration: 304805022, states[0] = -86.983715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315399158, states[0] = -87.027468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325075381, states[0] = 2.071550, states[40]= 0.004246
Saving checkpoint... 
Iteration: 333590237, states[0] = -7.246917, states[40]= 0.002770
Saving checkpoint... 
Iteration: 343030297, states[0] = 19.330068, states[40]= 0.005410
Saving checkpoint... 
Iteration: 351875540, states[0] = -87.019888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361165595, states[0] = -85.705662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370802638, states[0] = -86.981932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379429745, states[0] = -87.034968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387896328, states[0] = -87.026590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396952597, states[0] = -87.039322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406699145, states[0] = -86.853237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415794925, states[0] = -86.976040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424525870, states[0] = 20.480882, states[40]= 0.006104
Saving checkpoint... 
Iteration: 433553534, states[0] = 11.378414, states[40]= 0.004616
Saving checkpoint... 
Iteration: 443706497, states[0] = -86.866099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453010817, states[0] = 22.385328, states[40]= 0.038754
Saving checkpoint... 
Iteration: 461562463, states[0] = 7.890076, states[40]= 0.004567
Saving checkpoint... 
Iteration: 471175716, states[0] = -86.762230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480248987, states[0] = -86.929933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489358479, states[0] = -87.013169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498530897, states[0] = 19.159285, states[40]= 0.005346
Saving checkpoint... 
Iteration: 507769027, states[0] = -86.952618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517438319, states[0] = -87.036625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526755319, states[0] = -86.937562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534477618, states[0] = -87.043029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542573703, states[0] = 2.905511, states[40]= 0.004317
Saving checkpoint... 
Iteration: 551611727, states[0] = -26.732090, states[40]= 0.000591
Saving checkpoint... 
Iteration: 561802707, states[0] = -86.981852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570618383, states[0] = -32.991577, states[40]= 0.000313
Saving checkpoint... 
Iteration: 579930806, states[0] = -87.035057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589079620, states[0] = -0.185943, states[40]= 0.004002
Saving checkpoint... 
Iteration: 598732317, states[0] = -86.907367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607621480, states[0] = -35.934974, states[40]= 0.000213
Saving checkpoint... 
Iteration: 616658815, states[0] = -80.684342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625342292, states[0] = -87.005697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634276250, states[0] = -86.959671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643238438, states[0] = -86.915993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653575826, states[0] = 1.845674, states[40]= 0.004225
Saving checkpoint... 
Iteration: 662797183, states[0] = -86.977637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672000550, states[0] = 34.340849, states[40]= 0.002249
Saving checkpoint... 
Iteration: 681849872, states[0] = -87.009261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691492245, states[0] = -87.044752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700354583, states[0] = -87.011357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709253238, states[0] = -86.934975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718629980, states[0] = -44.285419, states[40]= 0.000062
Saving checkpoint... 
Iteration: 728754171, states[0] = -86.936073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738779602, states[0] = -86.962742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747976045, states[0] = -87.042675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756985307, states[0] = -87.043875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766908856, states[0] = -87.029791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776606711, states[0] = -22.039810, states[40]= 0.000803
Saving checkpoint... 
Iteration: 786345220, states[0] = -87.007013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796297269, states[0] = -86.977615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804767856, states[0] = -86.951213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813574925, states[0] = 2.301537, states[40]= 0.004267
Saving checkpoint... 
Iteration: 822320573, states[0] = -86.993626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831315674, states[0] = -86.990553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841586596, states[0] = -4.549932, states[40]= 0.003306
Saving checkpoint... 
Iteration: 852071796, states[0] = 3.818764, states[40]= 0.004384
Saving checkpoint... 
Iteration: 861999848, states[0] = -87.045489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871157462, states[0] = -78.889173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880787478, states[0] = -86.969623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889803518, states[0] = -86.982224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898885654, states[0] = -87.022961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907885851, states[0] = -87.023019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916549916, states[0] = 12.723825, states[40]= 0.004631
Saving checkpoint... 
Iteration: 926063729, states[0] = 7.369061, states[40]= 0.004553
Saving checkpoint... 
Iteration: 934994918, states[0] = -87.044897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943979232, states[0] = -87.042972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952656777, states[0] = -77.906830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962514953, states[0] = 22.168963, states[40]= 0.016394
Saving checkpoint... 
Iteration: 971355577, states[0] = -87.011610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980170530, states[0] = -86.554133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989594770, states[0] = -11.017093, states[40]= 0.002022
Saving checkpoint... 
Iteration: 998563769, states[0] = 7.352483, states[40]= 0.004552
Saving checkpoint... 
Iteration: 1008573725, states[0] = 2.894937, states[40]= 0.004317
Saving checkpoint... 
Iteration: 1017256500, states[0] = -86.938613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025834633, states[0] = -87.001509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034296632, states[0] = -86.976964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041901890, states[0] = -87.027739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051548100, states[0] = 13.388550, states[40]= 0.004642
Saving checkpoint... 
Iteration: 1060618685, states[0] = -33.276976, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1069503268, states[0] = 31.054658, states[40]= 0.154340
Saving checkpoint... 
Iteration: 1078679603, states[0] = -86.803776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087214697, states[0] = -86.879578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095594177, states[0] = -10.500980, states[40]= 0.002119
Saving checkpoint... 
Iteration: 1103084171, states[0] = -2.922966, states[40]= 0.003597
Saving checkpoint... 
Iteration: 1112247421, states[0] = -86.927543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121187982, states[0] = -86.832076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130327419, states[0] = -86.997464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138433170, states[0] = -87.035179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146802170, states[0] = -86.981070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154607822, states[0] = -23.078749, states[40]= 0.000754
Saving checkpoint... 
Iteration: 1164314136, states[0] = -86.989337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173299606, states[0] = -86.979145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182245182, states[0] = -86.924632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191442891, states[0] = -87.037055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200424666, states[0] = -87.033314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209091971, states[0] = -8.638330, states[40]= 0.002486
Saving checkpoint... 
Iteration: 1218830126, states[0] = -86.998930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228468617, states[0] = -87.041307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237251040, states[0] = -86.931963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246459085, states[0] = -87.039833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255440594, states[0] = -87.036577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264112160, states[0] = -27.137105, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1272963824, states[0] = -87.040559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281913307, states[0] = -87.030581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290953230, states[0] = -87.038836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299635768, states[0] = -50.341511, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1309465570, states[0] = -87.040801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319731308, states[0] = -86.905413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328481252, states[0] = -87.042981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337626899, states[0] = -41.194956, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1345410967, states[0] = -87.029950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356229806, states[0] = -86.903175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364425195, states[0] = -87.033323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373350500, states[0] = -87.009089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382613483, states[0] = -28.377271, states[40]= 0.000515
Saving checkpoint... 
Iteration: 1390671350, states[0] = -86.610532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399924093, states[0] = -87.033054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410101223, states[0] = -16.901335, states[40]= 0.001168
Saving checkpoint... 
Iteration: 1418758279, states[0] = -86.940390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427170839, states[0] = -86.576765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436733487, states[0] = -86.908497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446252636, states[0] = -86.933760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454548160, states[0] = 13.366789, states[40]= 0.004642
Saving checkpoint... 
Iteration: 1463934600, states[0] = -87.035256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472184669, states[0] = -86.824119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481451137, states[0] = -87.038351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489595353, states[0] = -11.529653, states[40]= 0.001929
Saving checkpoint... 
Iteration: 1497894335, states[0] = -87.025263, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.920958
 - CaMKt in component CaMK (millimolar): 0.006734
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.366636
 - nass in component intracellular_ions (millimolar): 6.366693
 - ki in component intracellular_ions (millimolar): 145.620012
 - kss in component intracellular_ions (millimolar): 145.619993
 - cansr in component intracellular_ions (millimolar): 1.282013
 - cajsr in component intracellular_ions (millimolar): 1.243583
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.008086
 - hf in component INa (dimensionless): 0.663981
 - hs in component INa (dimensionless): 0.663970
 - j in component INa (dimensionless): 0.663913
 - hsp in component INa (dimensionless): 0.416345
 - jp in component INa (dimensionless): 0.663874
 - mL in component INaL (dimensionless): 0.000226
 - hL in component INaL (dimensionless): 0.467883
 - hLp in component INaL (dimensionless): 0.240562
 - a in component Ito (dimensionless): 0.001068
 - iF in component Ito (dimensionless): 0.999473
 - iS in component Ito (dimensionless): 0.572138
 - ap in component Ito (dimensionless): 0.000544
 - iFp in component Ito (dimensionless): 0.999473
 - iSp in component Ito (dimensionless): 0.625411
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931752
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999877
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001476
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.412620
 - xs1 in component IKs (dimensionless): 0.252978
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.997002
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:17:57 (3428): called boinc_finish(0)

</stderr_txt>
]]>


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