𝕏

Task 55023670

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_176_0
Workunit 26127571
Created 27 Jun 2024, 18:02:21 UTC
Sent 28 Jun 2024, 2:09:27 UTC
Report deadline 1 Jul 2024, 2:09:27 UTC
Received 28 Jun 2024, 5:31:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 202888
Run time 1 hours 47 min 15 sec
CPU time 41 min 29 sec
Validate state Valid
Credit 41.69
Device peak FLOPS 3.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.86 MB
Peak swap size 6.40 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_176_0_r723779649_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_176_0_r723779649_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.195207
     * GNaL_b in INaL: 0.004477
     * Gto_b in Ito: 0.094224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029828
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.168074
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.901228
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029499
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9297293, states[0] = -53.040035, states[40]= 0.000314
Saving checkpoint... 
Iteration: 19246798, states[0] = -94.232648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 29388463, states[0] = -94.249046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 37940572, states[0] = -94.106323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46871574, states[0] = -93.966314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55871328, states[0] = -93.983199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64581738, states[0] = 22.250893, states[40]= 0.000004
Saving checkpoint... 
Iteration: 73523704, states[0] = 32.801000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83962086, states[0] = -94.265506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95580826, states[0] = -94.284819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103926459, states[0] = -94.147611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114593826, states[0] = -94.277113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122608160, states[0] = -94.289996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131951116, states[0] = -94.278043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143165243, states[0] = -94.295415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151399113, states[0] = -94.281535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160214904, states[0] = -94.288989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168680730, states[0] = -94.298681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178298495, states[0] = -94.286258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188274801, states[0] = -94.304076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198577032, states[0] = -94.278244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207413969, states[0] = -94.139455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216316570, states[0] = -93.842467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225264408, states[0] = -80.394024, states[40]= 0.000011
Saving checkpoint... 
Iteration: 235456001, states[0] = -94.280721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245291687, states[0] = -94.303971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254972693, states[0] = -94.279911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264940805, states[0] = -94.300596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273878909, states[0] = -94.302408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282301579, states[0] = -93.762338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290912524, states[0] = -94.281247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301082458, states[0] = -94.294100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310539006, states[0] = 32.784907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319595541, states[0] = 16.212533, states[40]= 0.000022
Saving checkpoint... 
Iteration: 329530037, states[0] = -94.295785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338037856, states[0] = -94.260073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348529587, states[0] = -94.255547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359068100, states[0] = -94.272665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367874450, states[0] = -94.052050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377235982, states[0] = -94.300201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386112950, states[0] = -94.285304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 395584837, states[0] = -94.292052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404514229, states[0] = -94.294892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414768045, states[0] = -94.300377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423076780, states[0] = 23.183395, states[40]= 0.000003
Saving checkpoint... 
Iteration: 432534330, states[0] = -94.256299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444516381, states[0] = -94.245873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454702098, states[0] = -30.640209, states[40]= 0.007577
Saving checkpoint... 
Iteration: 463125546, states[0] = -94.288873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472839966, states[0] = -93.939843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481808066, states[0] = -93.794165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490605379, states[0] = 12.381847, states[40]= 0.000056
Saving checkpoint... 
Iteration: 499637237, states[0] = -0.730201, states[40]= 0.000626
Saving checkpoint... 
Iteration: 509699216, states[0] = -94.284772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519313815, states[0] = -93.823312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528583217, states[0] = -94.274255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537018723, states[0] = 31.659700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544693465, states[0] = -27.178568, states[40]= 0.008508
Saving checkpoint... 
Iteration: 553592851, states[0] = 17.246286, states[40]= 0.000017
Saving checkpoint... 
Iteration: 562407669, states[0] = -94.275753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571189537, states[0] = -94.283875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580591232, states[0] = 17.863815, states[40]= 0.000014
Saving checkpoint... 
Iteration: 589729886, states[0] = -46.850506, states[40]= 0.001386
Saving checkpoint... 
Iteration: 598353059, states[0] = -94.276910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606925571, states[0] = -94.294076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616974686, states[0] = -94.210231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626472414, states[0] = -94.291922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637217844, states[0] = -94.281311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645896097, states[0] = -94.294202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654481881, states[0] = -94.215941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663334975, states[0] = -93.916083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672263211, states[0] = -78.515760, states[40]= 0.000014
Saving checkpoint... 
Iteration: 681305127, states[0] = -93.773755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690908510, states[0] = -94.292874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700417516, states[0] = -94.272506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709351162, states[0] = -94.274635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718213779, states[0] = -94.279768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 728345878, states[0] = -94.293665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738978208, states[0] = -94.289320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 749076012, states[0] = -94.267236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 758514105, states[0] = -94.287434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767128136, states[0] = -94.280486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776360814, states[0] = -94.292363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785278493, states[0] = -94.292727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795124095, states[0] = 4.916783, states[40]= 0.000263
Saving checkpoint... 
Iteration: 804481144, states[0] = -94.212115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812877728, states[0] = -94.271504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822156212, states[0] = -10.801842, states[40]= 0.001104
Saving checkpoint... 
Iteration: 830015180, states[0] = -94.236957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839147281, states[0] = -94.282314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847592083, states[0] = 17.542255, states[40]= 0.000015
Saving checkpoint... 
Iteration: 857745976, states[0] = -94.275521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867385035, states[0] = -94.067680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 877234878, states[0] = -94.275558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 886791809, states[0] = -93.689032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895733790, states[0] = -49.634232, states[40]= 0.000955
Saving checkpoint... 
Iteration: 904978494, states[0] = -94.207616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913433284, states[0] = -94.267487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922146860, states[0] = -94.278279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931437550, states[0] = -94.266965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940645964, states[0] = -5.004464, states[40]= 0.000913
Saving checkpoint... 
Iteration: 951179412, states[0] = -22.246922, states[40]= 0.006006
Saving checkpoint... 
Iteration: 960799155, states[0] = -94.289174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969451986, states[0] = -94.178859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979247881, states[0] = -94.272893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988166192, states[0] = -94.276075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997608176, states[0] = 11.288284, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1008091363, states[0] = 17.818150, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1017463476, states[0] = -94.190620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026875769, states[0] = -94.286744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036111541, states[0] = -94.277403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047372353, states[0] = -94.031907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055879092, states[0] = -94.266339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064170299, states[0] = -94.280713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071455928, states[0] = -94.181239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081502975, states[0] = 18.571157, states[40]= 1.392110
Saving checkpoint... 
Iteration: 1089828434, states[0] = -94.286304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098400784, states[0] = -94.096893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1108204306, states[0] = -94.271943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117056248, states[0] = -94.278089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125819965, states[0] = -94.285625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132166380, states[0] = -94.273026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141943524, states[0] = -94.164780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151800792, states[0] = -94.267182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161617604, states[0] = -94.269996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171838522, states[0] = -93.919124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180301007, states[0] = -94.266572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190444723, states[0] = -94.281102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200173341, states[0] = -19.911655, states[40]= 0.003684
Saving checkpoint... 
Iteration: 1209527504, states[0] = -94.236211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218522605, states[0] = -94.233234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228825149, states[0] = -93.861937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238340368, states[0] = -94.283013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247998357, states[0] = -94.258358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257746387, states[0] = -94.282050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267344748, states[0] = -94.263105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1276779334, states[0] = -93.430569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286097694, states[0] = -94.262504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295401284, states[0] = -94.280364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304498934, states[0] = -94.276566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314691848, states[0] = -94.277636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323927802, states[0] = -94.278894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332673805, states[0] = -94.275451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342053839, states[0] = -94.273448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351300067, states[0] = -94.263001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360355561, states[0] = -94.260749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368756651, states[0] = -94.280020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377115396, states[0] = 8.433459, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1385550533, states[0] = -94.272674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393133412, states[0] = -94.268930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401326028, states[0] = -93.862092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412986715, states[0] = -94.255237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420555587, states[0] = 29.800837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430641821, states[0] = -94.267778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441028553, states[0] = -94.272444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450242284, states[0] = -94.263181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457358998, states[0] = -94.278059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465765658, states[0] = -82.672736, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1476540695, states[0] = -94.237423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486994510, states[0] = -94.208666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495006266, states[0] = -94.272252, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.128958
 - CaMKt in component CaMK (millimolar): 0.004831
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.997697
 - nass in component intracellular_ions (millimolar): 7.997870
 - ki in component intracellular_ions (millimolar): 143.682422
 - kss in component intracellular_ions (millimolar): 143.682403
 - cansr in component intracellular_ions (millimolar): 1.997193
 - cajsr in component intracellular_ions (millimolar): 1.999662
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003912
 - hf in component INa (dimensionless): 0.865928
 - hs in component INa (dimensionless): 0.865930
 - j in component INa (dimensionless): 0.865937
 - hsp in component INa (dimensionless): 0.699881
 - jp in component INa (dimensionless): 0.865941
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708393
 - hLp in component INaL (dimensionless): 0.509923
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.963827
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981083
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985804
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005445
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034297
 - xs1 in component IKs (dimensionless): 0.092840
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:12:28 (5948): called boinc_finish(0)

</stderr_txt>
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