𝕏

Task 55023544

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_3000-conf_776_0
Workunit 26127508
Created 27 Jun 2024, 18:02:21 UTC
Sent 28 Jun 2024, 2:06:56 UTC
Report deadline 1 Jul 2024, 2:06:56 UTC
Received 30 Jun 2024, 6:44:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 196629
Run time 1 hours 58 min 46 sec
CPU time 1 hours 54 min 34 sec
Validate state Valid
Credit 41.92
Device peak FLOPS 3.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.91 MB
Peak swap size 6.21 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_3000-conf_776.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_3000-conf_776_0_r138220819_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_EPI_3000-conf_776_0_r138220819_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.938809
     * GNaL_b in INaL: 0.005199
     * Gto_b in Ito: 0.079092
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031778
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.162305
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.196270
     * GKb_b in IKb: 0.003692
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8449912, states[0] = -94.376714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16743962, states[0] = -93.912313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25261274, states[0] = -94.274219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33563455, states[0] = -94.277886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42198411, states[0] = -93.497107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50818974, states[0] = -94.249387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59087294, states[0] = -94.276476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67600856, states[0] = 2.401737, states[40]= 0.000141
Saving checkpoint... 
Iteration: 75797656, states[0] = -94.280210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84614491, states[0] = -94.286008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93575522, states[0] = -94.285960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102221267, states[0] = -93.700311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110700156, states[0] = -94.268850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119214058, states[0] = -94.292917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127888648, states[0] = -94.218030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136253684, states[0] = -94.269440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144736445, states[0] = -94.294373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153146155, states[0] = -44.855505, states[40]= 0.000189
Saving checkpoint... 
Iteration: 161541761, states[0] = -94.280109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170060303, states[0] = -94.291921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178421333, states[0] = -94.264784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187059777, states[0] = -94.279583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195528834, states[0] = -94.287549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203976799, states[0] = -94.263053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212556811, states[0] = -94.279674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220936597, states[0] = -94.256039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229453216, states[0] = -94.263602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237937427, states[0] = -94.285495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246324458, states[0] = -94.127127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254978826, states[0] = -94.262470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263572384, states[0] = -94.278328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272113444, states[0] = -94.295202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280475837, states[0] = -94.262191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289109813, states[0] = -94.276170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297301979, states[0] = -94.073360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305742369, states[0] = -94.270131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313331216, states[0] = -94.266575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319226713, states[0] = -94.270551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327480831, states[0] = -94.273878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336184868, states[0] = -92.440140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344143474, states[0] = -94.294796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352595586, states[0] = 5.085540, states[40]= 0.000098
Saving checkpoint... 
Iteration: 360997212, states[0] = -94.280492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369343177, states[0] = -94.159679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377902802, states[0] = -94.262973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386087453, states[0] = -94.291935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394378442, states[0] = -94.263537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402598957, states[0] = -94.292384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410870553, states[0] = -94.263536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419118689, states[0] = -94.292985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427415431, states[0] = -94.261715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436191603, states[0] = -94.270073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444662092, states[0] = -94.293216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453217309, states[0] = -93.674596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461576451, states[0] = -94.274878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470011181, states[0] = -94.279912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478263756, states[0] = -94.266388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486362558, states[0] = -94.186289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494749619, states[0] = -94.266675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502931809, states[0] = -94.248794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511295140, states[0] = -94.264612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519525014, states[0] = -94.281961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527919707, states[0] = -94.259882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536271247, states[0] = -94.288904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544765064, states[0] = -93.943663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553083326, states[0] = -94.273010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561316931, states[0] = -94.105725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569794704, states[0] = -94.263641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577947589, states[0] = -94.256089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586245702, states[0] = -94.265292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594692657, states[0] = -94.290396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603069686, states[0] = 18.295779, states[40]= 0.000004
Saving checkpoint... 
Iteration: 611630849, states[0] = -94.269804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619982955, states[0] = -94.269667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628539945, states[0] = 26.160585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636872551, states[0] = -94.282339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645195874, states[0] = -93.477591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653477911, states[0] = -94.276571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661809175, states[0] = -94.085740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670147376, states[0] = -94.268080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678426330, states[0] = -94.242489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686641128, states[0] = -94.268082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694861549, states[0] = -94.181434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702982659, states[0] = -94.275494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711350290, states[0] = -94.165146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719650296, states[0] = -94.267113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727954538, states[0] = -94.256867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735771381, states[0] = -94.285545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744211662, states[0] = -93.627575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752564293, states[0] = -94.270573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760735490, states[0] = -93.789754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769199001, states[0] = -94.264158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777557550, states[0] = -94.282574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786131074, states[0] = -27.952122, states[40]= 0.000449
Saving checkpoint... 
Iteration: 794380501, states[0] = -94.279286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802900908, states[0] = -94.221726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811339417, states[0] = -94.257908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819701862, states[0] = -94.286440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828096742, states[0] = 4.362458, states[40]= 0.000110
Saving checkpoint... 
Iteration: 836278440, states[0] = -94.283556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844806171, states[0] = -94.075076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853240118, states[0] = -94.261028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861317542, states[0] = -94.102000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869672145, states[0] = -94.263622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877911182, states[0] = -94.228665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886334458, states[0] = -94.256829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894439660, states[0] = -94.246664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902893977, states[0] = -94.254439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911141875, states[0] = -94.285265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919305344, states[0] = -94.257357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927734314, states[0] = -94.283724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936034355, states[0] = 26.440194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944508429, states[0] = -94.270115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952601298, states[0] = 1.315515, states[40]= 0.000169
Saving checkpoint... 
Iteration: 960882973, states[0] = -94.276353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969273938, states[0] = -93.971929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977744455, states[0] = -94.258755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986086769, states[0] = -94.281806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994374087, states[0] = -94.253584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002947056, states[0] = -94.272295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010998219, states[0] = -94.249241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019455430, states[0] = -94.271583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027735980, states[0] = -93.788068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036063401, states[0] = -94.265848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044271715, states[0] = -93.962101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052417822, states[0] = -94.272993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060710220, states[0] = -93.610983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068930660, states[0] = -94.272041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077186080, states[0] = -92.741433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085464091, states[0] = -94.270018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093819870, states[0] = -94.103179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102426355, states[0] = -94.249981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110777539, states[0] = -94.278979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119283022, states[0] = -94.001965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127594040, states[0] = -94.262835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135727761, states[0] = -93.734751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144051087, states[0] = -94.264632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152370270, states[0] = -94.184748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160910985, states[0] = -94.249516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169097153, states[0] = -94.279411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177543266, states[0] = 25.788188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185810323, states[0] = -94.276233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194301595, states[0] = -94.057083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203032657, states[0] = 26.432846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211392541, states[0] = -94.271647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219981148, states[0] = -94.258992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228330182, states[0] = -94.251225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236549484, states[0] = -94.273844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244825437, states[0] = -94.251124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253283966, states[0] = -94.276312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261759233, states[0] = -93.905793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270128621, states[0] = -94.258836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278688474, states[0] = -94.278987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287088288, states[0] = 9.365744, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1295522144, states[0] = -94.263524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303948128, states[0] = -94.244143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312289775, states[0] = -94.251335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320736727, states[0] = -94.277042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327001986, states[0] = -94.264011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327279963, states[0] = -94.251463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336129391, states[0] = -94.257686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345385529, states[0] = -94.247275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354541766, states[0] = 25.977353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363682144, states[0] = -91.113509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372757688, states[0] = -93.896800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381955917, states[0] = -94.246492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390953157, states[0] = -94.245081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399769994, states[0] = -93.949227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408532962, states[0] = 26.438745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417346736, states[0] = -94.247439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426206282, states[0] = -94.252788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435070414, states[0] = -94.258795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443558942, states[0] = -94.271544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452264718, states[0] = -93.926620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460542534, states[0] = -94.259728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469300944, states[0] = -94.271907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477896705, states[0] = -94.206696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486542643, states[0] = 25.871755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495149505, states[0] = -94.254099, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.116908
 - CaMKt in component CaMK (millimolar): 0.003731
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.168361
 - nass in component intracellular_ions (millimolar): 7.168504
 - ki in component intracellular_ions (millimolar): 144.454468
 - kss in component intracellular_ions (millimolar): 144.454451
 - cansr in component intracellular_ions (millimolar): 2.496770
 - cajsr in component intracellular_ions (millimolar): 2.497288
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003917
 - hf in component INa (dimensionless): 0.865698
 - hs in component INa (dimensionless): 0.865700
 - j in component INa (dimensionless): 0.865707
 - hsp in component INa (dimensionless): 0.699465
 - jp in component INa (dimensionless): 0.865711
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.708063
 - hLp in component INaL (dimensionless): 0.511797
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991107
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005588
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.025279
 - xs1 in component IKs (dimensionless): 0.068737
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997536
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:08:22 (6496): called boinc_finish(0)

</stderr_txt>
]]>


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