𝕏

Task 55022701

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_75_1
Workunit 26127127
Created 27 Jun 2024, 18:01:59 UTC
Sent 28 Jun 2024, 1:53:30 UTC
Report deadline 1 Jul 2024, 11:29:30 UTC
Received 28 Jun 2024, 21:07:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216978
Run time 10 hours 31 min 26 sec
CPU time 10 hours 28 min 47 sec
Validate state Valid
Credit 58.50
Device peak FLOPS 1.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.23 MB
Peak swap size 11.08 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_75.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_75_1_r1103368793_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_75_1_r1103368793_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.914909
     * GNaL_b in INaL: 0.007413
     * Gto_b in Ito: 0.070939
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030854
     * GKs_b in IKs: 0.002060
     * GK1_b in IK1: 0.156847
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 74.038573
     * GKb_b in IKb: 0.003890
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018788
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11605630, states[0] = -26.231539, states[40]= 0.000648
Saving checkpoint... 
Iteration: 23143903, states[0] = -63.737799, states[40]= 0.000003
Saving checkpoint... 
Iteration: 34771013, states[0] = -94.872712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46349532, states[0] = -94.916812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57672710, states[0] = -94.037006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69167473, states[0] = -91.484401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80754727, states[0] = -94.813633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92192071, states[0] = -94.698411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103774510, states[0] = -94.831072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115305409, states[0] = -94.857888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127111432, states[0] = -26.313736, states[40]= 0.000690
Saving checkpoint... 
Iteration: 138494209, states[0] = -94.924596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149744782, states[0] = -94.789219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161134578, states[0] = -48.133171, states[40]= 0.000040
Saving checkpoint... 
Iteration: 172552361, states[0] = 11.953007, states[40]= 0.005179
Saving checkpoint... 
Iteration: 183872234, states[0] = -94.892940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195312229, states[0] = -94.859207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206647425, states[0] = -62.074225, states[40]= 0.000004
Saving checkpoint... 
Iteration: 218044428, states[0] = 15.036947, states[40]= 0.005385
Saving checkpoint... 
Iteration: 229570426, states[0] = 4.254108, states[40]= 0.004772
Saving checkpoint... 
Iteration: 241181752, states[0] = -94.597482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252744551, states[0] = -94.787379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264314972, states[0] = -94.860835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275621105, states[0] = -34.921884, states[40]= 0.000280
Saving checkpoint... 
Iteration: 286899845, states[0] = -94.902437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298280532, states[0] = -94.831256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309504264, states[0] = 33.753699, states[40]= 0.138631
Saving checkpoint... 
Iteration: 320630932, states[0] = -44.329684, states[40]= 0.000072
Saving checkpoint... 
Iteration: 332043783, states[0] = 15.283795, states[40]= 0.005409
Saving checkpoint... 
Iteration: 343546287, states[0] = 14.330328, states[40]= 0.005322
Saving checkpoint... 
Iteration: 355016045, states[0] = 23.876764, states[40]= 0.016821
Saving checkpoint... 
Iteration: 366379046, states[0] = -94.895039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378326916, states[0] = -94.868829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389841403, states[0] = -94.877463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401470174, states[0] = -94.918813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412923901, states[0] = -94.909224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424483725, states[0] = -94.920903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436176115, states[0] = -94.259189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447738593, states[0] = -94.778297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459026235, states[0] = 21.297794, states[40]= 0.007420
Saving checkpoint... 
Iteration: 470802741, states[0] = -94.851327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482194687, states[0] = -94.696391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493808036, states[0] = -94.855501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505232156, states[0] = -94.768066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516569301, states[0] = 4.785423, states[40]= 0.004812
Saving checkpoint... 
Iteration: 528001270, states[0] = 50.251258, states[40]= 0.041616
Saving checkpoint... 
Iteration: 539521339, states[0] = 22.629618, states[40]= 0.009590
Saving checkpoint... 
Iteration: 550918517, states[0] = -94.907741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562540428, states[0] = 16.536042, states[40]= 0.005567
Saving checkpoint... 
Iteration: 574318377, states[0] = -94.863026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585881679, states[0] = -94.895927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597614009, states[0] = -28.471806, states[40]= 0.000581
Saving checkpoint... 
Iteration: 609253485, states[0] = -94.799544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620998498, states[0] = -94.922797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632792713, states[0] = -94.842680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644667606, states[0] = -90.448376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656541009, states[0] = 16.321553, states[40]= 0.005536
Saving checkpoint... 
Iteration: 668465714, states[0] = -94.917915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680158228, states[0] = -76.413635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691971704, states[0] = -94.918907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703588716, states[0] = -6.437556, states[40]= 0.003118
Saving checkpoint... 
Iteration: 715241116, states[0] = -94.781985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727093537, states[0] = -10.252769, states[40]= 0.002297
Saving checkpoint... 
Iteration: 738763663, states[0] = -94.812353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750833489, states[0] = -94.872697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762795362, states[0] = -94.844955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774444327, states[0] = -94.913772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786132993, states[0] = -46.422141, states[40]= 0.000052
Saving checkpoint... 
Iteration: 797949616, states[0] = -94.914847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809388487, states[0] = -94.898303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821021357, states[0] = 22.625116, states[40]= 0.009578
Saving checkpoint... 
Iteration: 832755869, states[0] = -94.802557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844644018, states[0] = -58.197057, states[40]= 0.000007
Saving checkpoint... 
Iteration: 856511627, states[0] = 24.988366, states[40]= 0.037318
Saving checkpoint... 
Iteration: 868292542, states[0] = -94.842399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879892954, states[0] = -94.899818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891694263, states[0] = -94.695098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903361047, states[0] = -94.887130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914679461, states[0] = -94.518580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926170852, states[0] = -92.831099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938019270, states[0] = 23.135916, states[40]= 0.011402
Saving checkpoint... 
Iteration: 949910935, states[0] = -94.905417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961676469, states[0] = -94.299408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973017414, states[0] = 23.566850, states[40]= 0.013982
Saving checkpoint... 
Iteration: 984881671, states[0] = -94.895708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996598336, states[0] = -14.403965, states[40]= 0.001564
Saving checkpoint... 
Iteration: 1007962623, states[0] = -94.917190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019912553, states[0] = -94.905842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031574867, states[0] = 2.070930, states[40]= 0.004568
Saving checkpoint... 
Iteration: 1043289639, states[0] = -94.839657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054868568, states[0] = -94.890389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066657651, states[0] = -75.515712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078399679, states[0] = -94.901931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089987304, states[0] = -94.921053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101552520, states[0] = 11.902376, states[40]= 0.005176
Saving checkpoint... 
Iteration: 1113191496, states[0] = -94.687103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124638046, states[0] = -51.713391, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1136295228, states[0] = -94.844634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147906779, states[0] = -94.904090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159609164, states[0] = -24.120300, states[40]= 0.000794
Saving checkpoint... 
Iteration: 1171602330, states[0] = -17.981106, states[40]= 0.001151
Saving checkpoint... 
Iteration: 1183377455, states[0] = -94.893972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195046843, states[0] = 14.116906, states[40]= 0.005306
Saving checkpoint... 
Iteration: 1207105659, states[0] = -20.975642, states[40]= 0.000944
Saving checkpoint... 
Iteration: 1218547785, states[0] = 13.753619, states[40]= 0.005280
Saving checkpoint... 
Iteration: 1230270577, states[0] = -94.820113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242135686, states[0] = -49.217304, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1253753264, states[0] = -94.798899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264989565, states[0] = -94.921273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276563584, states[0] = 7.346309, states[40]= 0.004972
Saving checkpoint... 
Iteration: 1288272008, states[0] = -94.821674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299890611, states[0] = -94.898784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311450394, states[0] = -94.914725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322904138, states[0] = -94.903195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334186916, states[0] = -94.665862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345591230, states[0] = -8.371536, states[40]= 0.002695
Saving checkpoint... 
Iteration: 1357577805, states[0] = 0.515157, states[40]= 0.004383
Saving checkpoint... 
Iteration: 1369194562, states[0] = -94.695593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380913984, states[0] = -94.906049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392525971, states[0] = 21.374621, states[40]= 0.007496
Saving checkpoint... 
Iteration: 1404198496, states[0] = -94.704647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415680748, states[0] = -94.568291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427355914, states[0] = -94.884424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438931908, states[0] = -94.910637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450790429, states[0] = -94.840163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462282930, states[0] = -94.833008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473855059, states[0] = -94.883984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485411706, states[0] = -94.905348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496968136, states[0] = -94.917880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508510765, states[0] = -41.738742, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1519847803, states[0] = 10.496029, states[40]= 0.005916
Saving checkpoint... 
Iteration: 1531175304, states[0] = -95.166913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542728166, states[0] = -64.815502, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1554505852, states[0] = -95.089943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566019299, states[0] = 22.720179, states[40]= 0.012860
Saving checkpoint... 
Iteration: 1577511665, states[0] = -45.607619, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1589055475, states[0] = -95.170619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600388531, states[0] = -95.064743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611896475, states[0] = -95.209019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623495404, states[0] = -95.081033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635119486, states[0] = -55.147008, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1646889743, states[0] = -95.069648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658603734, states[0] = -95.098531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669951954, states[0] = -94.560691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681670638, states[0] = -95.023257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692978154, states[0] = -10.857069, states[40]= 0.002463
Saving checkpoint... 
Iteration: 1704594274, states[0] = -95.209234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715921286, states[0] = -95.129432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727414089, states[0] = 24.460472, states[40]= 0.024767
Saving checkpoint... 
Iteration: 1738784150, states[0] = -95.201562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750257739, states[0] = 4.480412, states[40]= 0.005437
Saving checkpoint... 
Iteration: 1761857802, states[0] = -95.177149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773099459, states[0] = -32.780975, states[40]= 0.000358
Saving checkpoint... 
Iteration: 1784665367, states[0] = -95.184868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796257257, states[0] = -94.909153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807569433, states[0] = 3.392488, states[40]= 0.004828
Saving checkpoint... 
Iteration: 1819019495, states[0] = 22.741329, states[40]= 0.010929
Saving checkpoint... 
Iteration: 1830341009, states[0] = -94.905328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841949534, states[0] = -94.934676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853255386, states[0] = -94.816079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864784830, states[0] = -94.844968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876158570, states[0] = -77.806423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887574306, states[0] = 2.230008, states[40]= 0.004591
Saving checkpoint... 
Iteration: 1899139272, states[0] = -53.288036, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1910407337, states[0] = -94.906390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921971069, states[0] = -94.919922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933473394, states[0] = -94.919758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945058717, states[0] = 9.384505, states[40]= 0.005068
Saving checkpoint... 
Iteration: 1956463965, states[0] = -94.917519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967953401, states[0] = -94.915376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979571840, states[0] = 3.572473, states[40]= 0.004715
Saving checkpoint... 
Iteration: 1991045684, states[0] = 14.558255, states[40]= 0.005341
Saving checkpoint... 
Iteration: 2002521722, states[0] = 22.531098, states[40]= 0.009336
Saving checkpoint... 
Iteration: 2014203175, states[0] = -94.714152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025621253, states[0] = -35.060056, states[40]= 0.000274
Saving checkpoint... 
Iteration: 2036682928, states[0] = -94.620848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048405422, states[0] = -94.903191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060138064, states[0] = -51.733974, states[40]= 0.000022
Saving checkpoint... 
Iteration: 2071645484, states[0] = -59.836553, states[40]= 0.000006
Saving checkpoint... 
Iteration: 2083274594, states[0] = -94.824033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094586088, states[0] = -4.556160, states[40]= 0.003518
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.798026
 - CaMKt in component CaMK (millimolar): 0.006840
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.509354
 - nass in component intracellular_ions (millimolar): 6.509414
 - ki in component intracellular_ions (millimolar): 145.470904
 - kss in component intracellular_ions (millimolar): 145.470885
 - cansr in component intracellular_ions (millimolar): 1.304674
 - cajsr in component intracellular_ions (millimolar): 1.266471
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003657
 - hf in component INa (dimensionless): 0.878188
 - hs in component INa (dimensionless): 0.878183
 - j in component INa (dimensionless): 0.878151
 - hsp in component INa (dimensionless): 0.722420
 - jp in component INa (dimensionless): 0.878130
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705728
 - hLp in component INaL (dimensionless): 0.444688
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.614706
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.687678
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929190
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999863
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.352661
 - xs1 in component IKs (dimensionless): 0.251098
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997364
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:18:44 (97911): called boinc_finish(0)

</stderr_txt>
]]>


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