𝕏

Task 55015748

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_869_0
Workunit 26123669
Created 27 Jun 2024, 17:58:50 UTC
Sent 28 Jun 2024, 0:51:05 UTC
Report deadline 1 Jul 2024, 0:51:05 UTC
Received 28 Jun 2024, 6:33:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237478
Run time 2 hours 53 min 43 sec
CPU time 2 hours 42 min 25 sec
Validate state Valid
Credit 42.18
Device peak FLOPS 2.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.57 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_869.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_869_0_r572386911_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_869_0_r572386911_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.691321
     * GNaL_b in INaL: 0.004604
     * Gto_b in Ito: 0.085436
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031689
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.172691
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 70.743591
     * GKb_b in IKb: 0.003848
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052351
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8849880, states[0] = -95.090112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17721848, states[0] = -94.842630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26684072, states[0] = -94.670192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35532425, states[0] = 22.803242, states[40]= 0.002517
Saving checkpoint... 
Iteration: 44455081, states[0] = -95.063465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53337197, states[0] = -94.997839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62264973, states[0] = -94.896676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71189365, states[0] = -94.663268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80062107, states[0] = 11.060464, states[40]= 0.004490
Saving checkpoint... 
Iteration: 88962528, states[0] = -95.056126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97888663, states[0] = -95.027374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106814416, states[0] = -94.967050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115726778, states[0] = -94.796957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124573441, states[0] = 5.287231, states[40]= 0.004927
Saving checkpoint... 
Iteration: 133410874, states[0] = -95.036490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142321254, states[0] = -94.973430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151220054, states[0] = -94.774916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160090908, states[0] = -7.300610, states[40]= 0.003355
Saving checkpoint... 
Iteration: 168948457, states[0] = -95.049325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177893779, states[0] = -95.027746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186743192, states[0] = -94.840926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195624074, states[0] = -40.895621, states[40]= 0.000285
Saving checkpoint... 
Iteration: 204495368, states[0] = -95.060003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213380704, states[0] = -95.020356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222346330, states[0] = -94.996331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231242121, states[0] = -94.837945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240118101, states[0] = -34.772600, states[40]= 0.000585
Saving checkpoint... 
Iteration: 249017258, states[0] = 26.808510, states[40]= 0.006006
Saving checkpoint... 
Iteration: 257914377, states[0] = -95.036799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266820255, states[0] = -94.971357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275732517, states[0] = -94.811913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284632945, states[0] = -50.335578, states[40]= 0.000075
Saving checkpoint... 
Iteration: 293534377, states[0] = 22.335812, states[40]= 0.002611
Saving checkpoint... 
Iteration: 302447272, states[0] = -95.048274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311393332, states[0] = -95.026881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320258115, states[0] = -94.875003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329132423, states[0] = -49.766988, states[40]= 0.000082
Saving checkpoint... 
Iteration: 338050526, states[0] = 16.198342, states[40]= 0.003700
Saving checkpoint... 
Iteration: 346882932, states[0] = -95.021139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355748976, states[0] = -94.854342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364536282, states[0] = 21.668904, states[40]= 0.002715
Saving checkpoint... 
Iteration: 373460218, states[0] = -95.051660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382291239, states[0] = -94.934023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391164408, states[0] = -92.217050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400004048, states[0] = 34.164587, states[40]= 0.328748
Saving checkpoint... 
Iteration: 408903037, states[0] = -95.031309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417828139, states[0] = -94.979077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426663920, states[0] = -91.865920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435570159, states[0] = 7.117014, states[40]= 0.004864
Saving checkpoint... 
Iteration: 444440630, states[0] = -95.045766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453386155, states[0] = -95.022604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462265261, states[0] = -94.889212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471153387, states[0] = -76.028197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472897392, states[0] = -95.028401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481411073, states[0] = -95.034669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490158435, states[0] = -84.845697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498832890, states[0] = -94.983452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507478568, states[0] = -95.055603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516210756, states[0] = -94.741599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524941141, states[0] = -95.045671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533670356, states[0] = -94.204135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542364483, states[0] = -95.008954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551027952, states[0] = 24.405656, states[40]= 0.002386
Saving checkpoint... 
Iteration: 559676657, states[0] = -94.553826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568323435, states[0] = -94.973772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576789698, states[0] = -94.931093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585419742, states[0] = -95.037901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594167515, states[0] = -93.649354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602801914, states[0] = -94.948261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611484103, states[0] = -95.056435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620175161, states[0] = -94.516921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628936189, states[0] = -95.043727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637678089, states[0] = -94.577775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646298394, states[0] = -94.943381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654970344, states[0] = -95.053274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663676986, states[0] = -94.559801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672448785, states[0] = -95.047534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681129216, states[0] = -46.306366, states[40]= 0.000136
Saving checkpoint... 
Iteration: 689811542, states[0] = -94.960066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698508525, states[0] = 27.736108, states[40]= 0.079954
Saving checkpoint... 
Iteration: 707187612, states[0] = -94.648018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715784668, states[0] = -94.922851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724361624, states[0] = -95.006378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733003746, states[0] = 35.404460, states[40]= 0.355118
Saving checkpoint... 
Iteration: 741615975, states[0] = -32.619620, states[40]= 0.000717
Saving checkpoint... 
Iteration: 750198199, states[0] = -94.693245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758906493, states[0] = -95.031769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767543250, states[0] = 19.087382, states[40]= 0.003166
Saving checkpoint... 
Iteration: 775945522, states[0] = -95.046228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784610598, states[0] = -27.205692, states[40]= 0.001013
Saving checkpoint... 
Iteration: 793274865, states[0] = -94.906118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802023571, states[0] = 25.592191, states[40]= 0.002584
Saving checkpoint... 
Iteration: 810673153, states[0] = -94.435531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819340654, states[0] = -94.989522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828026713, states[0] = 24.763755, states[40]= 0.002390
Saving checkpoint... 
Iteration: 836787013, states[0] = -94.926150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845483996, states[0] = -95.055665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854204728, states[0] = -94.718352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862943692, states[0] = -95.045390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871633024, states[0] = -50.418314, states[40]= 0.000074
Saving checkpoint... 
Iteration: 880280564, states[0] = -94.915636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888877626, states[0] = -95.016297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897504454, states[0] = 32.767746, states[40]= 0.293468
Saving checkpoint... 
Iteration: 906138698, states[0] = -56.689145, states[40]= 0.000028
Saving checkpoint... 
Iteration: 914717395, states[0] = -94.763224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923327898, states[0] = -94.977215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931952324, states[0] = -95.047725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940557966, states[0] = 13.023472, states[40]= 0.004239
Saving checkpoint... 
Iteration: 949161980, states[0] = -90.021290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957767344, states[0] = -94.891678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966314281, states[0] = -94.962396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974933149, states[0] = -95.041592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983617129, states[0] = -33.784205, states[40]= 0.000645
Saving checkpoint... 
Iteration: 990409692, states[0] = -95.032444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999015780, states[0] = 26.987363, states[40]= 0.008633
Saving checkpoint... 
Iteration: 1007639383, states[0] = -57.461944, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1015942443, states[0] = -95.044512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024559184, states[0] = 12.478249, states[40]= 0.004320
Saving checkpoint... 
Iteration: 1033243113, states[0] = -94.837829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041919405, states[0] = -95.036308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050509914, states[0] = 27.452192, states[40]= 0.050830
Saving checkpoint... 
Iteration: 1059272370, states[0] = -94.900775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067976257, states[0] = -95.053306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076654194, states[0] = -77.381436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085245237, states[0] = -94.842960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093868610, states[0] = -95.009965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102511439, states[0] = 27.310626, states[40]= 0.031135
Saving checkpoint... 
Iteration: 1111251220, states[0] = -94.857144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119923248, states[0] = -95.037547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128573330, states[0] = 5.376534, states[40]= 0.004929
Saving checkpoint... 
Iteration: 1137180232, states[0] = -94.600720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145952884, states[0] = -95.047199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154626714, states[0] = -43.646210, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1163309205, states[0] = -94.955727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171989348, states[0] = -95.055687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180574201, states[0] = 4.878877, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1189151181, states[0] = -72.509537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1197798819, states[0] = -94.942192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206480147, states[0] = -95.053709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215060139, states[0] = 12.045125, states[40]= 0.004381
Saving checkpoint... 
Iteration: 1223731437, states[0] = -94.805754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232449612, states[0] = -95.045986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241048174, states[0] = 17.154123, states[40]= 0.003525
Saving checkpoint... 
Iteration: 1249729584, states[0] = -94.800296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258438401, states[0] = -95.042445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267028720, states[0] = 24.176909, states[40]= 0.002396
Saving checkpoint... 
Iteration: 1275710053, states[0] = -94.736619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284448322, states[0] = -95.045441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293158549, states[0] = -85.029339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301925137, states[0] = -95.037676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310578210, states[0] = 2.460781, states[40]= 0.004895
Saving checkpoint... 
Iteration: 1319222349, states[0] = -94.778022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327957877, states[0] = -95.047989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336644251, states[0] = -63.154393, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1345313901, states[0] = -94.960740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353950206, states[0] = -95.045770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362551280, states[0] = 15.888878, states[40]= 0.003757
Saving checkpoint... 
Iteration: 1371220078, states[0] = -94.770573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379870284, states[0] = -95.010143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388558299, states[0] = 12.875711, states[40]= 0.004261
Saving checkpoint... 
Iteration: 1397326071, states[0] = -94.973845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405970399, states[0] = -95.050888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414632172, states[0] = -49.489395, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1423315397, states[0] = -94.962214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432015240, states[0] = 27.041995, states[40]= 0.009978
Saving checkpoint... 
Iteration: 1440681601, states[0] = -94.611158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449282436, states[0] = -94.916894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458023982, states[0] = 25.491625, states[40]= 0.002537
Saving checkpoint... 
Iteration: 1466687688, states[0] = -94.645905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475335809, states[0] = -94.983058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484013608, states[0] = 27.174364, states[40]= 0.015928
Saving checkpoint... 
Iteration: 1492629115, states[0] = -46.194943, states[40]= 0.000138
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.932462
 - CaMKt in component CaMK (millimolar): 0.012087
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.687650
 - nass in component intracellular_ions (millimolar): 6.687746
 - ki in component intracellular_ions (millimolar): 145.206458
 - kss in component intracellular_ions (millimolar): 145.206436
 - cansr in component intracellular_ions (millimolar): 1.631453
 - cajsr in component intracellular_ions (millimolar): 1.590614
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003607
 - hf in component INa (dimensionless): 0.880531
 - hs in component INa (dimensionless): 0.880524
 - j in component INa (dimensionless): 0.880480
 - hsp in component INa (dimensionless): 0.726816
 - jp in component INa (dimensionless): 0.880450
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709955
 - hLp in component INaL (dimensionless): 0.450924
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.618885
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.691366
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.921147
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999855
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002884
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.357544
 - xs1 in component IKs (dimensionless): 0.257662
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:33:21 (15195): called boinc_finish(0)

</stderr_txt>
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