𝕏

Task 55009096

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_8000-conf_562_0
Workunit 26120345
Created 27 Jun 2024, 17:55:55 UTC
Sent 27 Jun 2024, 23:57:57 UTC
Report deadline 30 Jun 2024, 23:57:57 UTC
Received 28 Jun 2024, 14:13:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 54 min 55 sec
CPU time 1 hours 50 min 3 sec
Validate state Valid
Credit 38.24
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.98 MB
Peak swap size 32.57 GB
Peak disk usage 2.47 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_8000-conf_562.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_8000-conf_562_0_r1472762559_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_8000-conf_562_0_r1472762559_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.907096
     * GNaL_b in INaL: 0.004785
     * Gto_b in Ito: 0.084005
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032160
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.175355
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.668521
     * GKb_b in IKb: 0.003730
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021992
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13375942, states[0] = -84.156879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26628354, states[0] = -84.039197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40095029, states[0] = 4.458592, states[40]= 0.001236
Saving checkpoint... 
Iteration: 53629428, states[0] = -83.969382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67178536, states[0] = -83.936211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80742558, states[0] = -83.967680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94309134, states[0] = -83.922427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107873972, states[0] = -83.910275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121483687, states[0] = -83.928209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135089967, states[0] = -83.905762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148634757, states[0] = -83.940309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162200305, states[0] = -83.908657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175931477, states[0] = -83.899502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189560911, states[0] = -83.918518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203157744, states[0] = -83.900035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216655988, states[0] = -83.938852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230240161, states[0] = -83.905354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243838001, states[0] = -83.897567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257424809, states[0] = -83.920978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 271018424, states[0] = -83.899455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284588766, states[0] = -83.928278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298250589, states[0] = -83.904627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311713501, states[0] = -83.897309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325298860, states[0] = -83.924896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338906513, states[0] = -83.899670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352499283, states[0] = -83.898606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366176893, states[0] = -83.905281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379796277, states[0] = -83.897010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393447999, states[0] = -83.919767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407133321, states[0] = -83.898610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420768690, states[0] = -83.942687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434321912, states[0] = -83.903598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 447858852, states[0] = -83.896813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461399467, states[0] = -83.921206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474971226, states[0] = -83.899162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488550390, states[0] = -83.918244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502146158, states[0] = -83.905466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515742881, states[0] = -83.896915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529301046, states[0] = -83.924503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542891495, states[0] = -83.899444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556504768, states[0] = -83.900938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570043868, states[0] = -83.906742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583654417, states[0] = -83.896993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597243339, states[0] = -83.926571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610731250, states[0] = -83.900216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 624431467, states[0] = -83.852054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638276164, states[0] = -83.903809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651911697, states[0] = -83.896480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665726068, states[0] = -83.912222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679479676, states[0] = -83.897249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692977098, states[0] = -83.937326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706684091, states[0] = -83.900384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720342084, states[0] = -83.723012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733705154, states[0] = -83.912595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 747302146, states[0] = -83.897634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760723767, states[0] = -83.941451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774396069, states[0] = -83.902474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788044483, states[0] = 25.136005, states[40]= 0.000091
Saving checkpoint... 
Iteration: 801562630, states[0] = -83.915975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814953698, states[0] = -83.898819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828665509, states[0] = -83.938087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842443409, states[0] = -83.901976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856255513, states[0] = -83.433729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870036910, states[0] = -83.906472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883654504, states[0] = -83.896623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897456273, states[0] = -83.918883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911274438, states[0] = -83.897514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925094769, states[0] = -83.932174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938898845, states[0] = -83.898920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952748156, states[0] = -83.941804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966522740, states[0] = -83.901184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980333675, states[0] = -83.703853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994123689, states[0] = -83.905143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007949676, states[0] = -83.895988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021771418, states[0] = -83.910836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035565573, states[0] = -83.896617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049415202, states[0] = -83.919975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063196706, states[0] = -83.897574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077004083, states[0] = -83.935770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090814351, states[0] = -83.899160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104602973, states[0] = -83.929817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118300386, states[0] = -83.902968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132116761, states[0] = -6.516462, states[40]= 0.001555
Saving checkpoint... 
Iteration: 1146003562, states[0] = -83.906621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159757599, states[0] = -83.896096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173577838, states[0] = -83.915118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187352250, states[0] = -83.896949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201155215, states[0] = -83.929328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214975761, states[0] = -83.898229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228697859, states[0] = -83.939792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242574136, states[0] = -83.900462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256449325, states[0] = -83.866377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270217183, states[0] = -83.903676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284006343, states[0] = 28.916987, states[40]= 0.186302
Saving checkpoint... 
Iteration: 1297768720, states[0] = -83.910552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311597939, states[0] = -83.896209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325416815, states[0] = -83.919585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339193267, states[0] = -83.897245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353041100, states[0] = -83.933900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366832200, states[0] = -83.898726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380687150, states[0] = -83.938993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394507445, states[0] = -83.900775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408293047, states[0] = -83.587036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422143284, states[0] = -83.904369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436200558, states[0] = -81.286825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449613890, states[0] = -83.913859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463234359, states[0] = -83.896958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476494382, states[0] = -83.894742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489119883, states[0] = -83.930434, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.771299
 - CaMKt in component CaMK (millimolar): 0.000853
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.203215
 - nass in component intracellular_ions (millimolar): 6.203322
 - ki in component intracellular_ions (millimolar): 145.704142
 - kss in component intracellular_ions (millimolar): 145.704133
 - cansr in component intracellular_ions (millimolar): 1.638384
 - cajsr in component intracellular_ions (millimolar): 1.638442
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.011091
 - hf in component INa (dimensionless): 0.540795
 - hs in component INa (dimensionless): 0.540795
 - j in component INa (dimensionless): 0.540795
 - hsp in component INa (dimensionless): 0.298346
 - jp in component INa (dimensionless): 0.540796
 - mL in component INaL (dimensionless): 0.000411
 - hL in component INaL (dimensionless): 0.378466
 - hLp in component INaL (dimensionless): 0.210154
 - a in component Ito (dimensionless): 0.001320
 - iF in component Ito (dimensionless): 0.999085
 - iS in component Ito (dimensionless): 0.998889
 - ap in component Ito (dimensionless): 0.000673
 - iFp in component Ito (dimensionless): 0.999085
 - iSp in component Ito (dimensionless): 0.999008
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999939
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003554
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.000992
 - xs1 in component IKs (dimensionless): 0.005862
 - xs2 in component IKs (dimensionless): 0.000305
 - xk1 in component IK1 (dimensionless): 0.996972
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:12:11 (1883): called boinc_finish(0)

</stderr_txt>
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