𝕏

Task 55004582

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758_0
Workunit 26118088
Created 27 Jun 2024, 17:53:54 UTC
Sent 27 Jun 2024, 23:21:43 UTC
Report deadline 30 Jun 2024, 23:21:43 UTC
Received 28 Jun 2024, 2:40:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227241
Run time 2 hours 14 min 22 sec
CPU time 2 hours 4 min 18 sec
Validate state Valid
Credit 40.96
Device peak FLOPS 2.94 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.25 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758_0_r395133575_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758_0_r395133575_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.618069
     * GNaL_b in INaL: 0.004725
     * Gto_b in Ito: 0.073691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033464
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.180768
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.023762
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023143
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10577452, states[0] = -44.744286, states[40]= 0.000068
Saving checkpoint... 
Iteration: 23311654, states[0] = -87.681208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36011321, states[0] = 21.151843, states[40]= 0.020060
Saving checkpoint... 
Iteration: 48906258, states[0] = -44.355953, states[40]= 0.000087
Saving checkpoint... 
Iteration: 61940850, states[0] = -87.489677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74636815, states[0] = -87.690846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86414196, states[0] = -62.757675, states[40]= 0.000005
Saving checkpoint... 
Iteration: 98566422, states[0] = -42.593254, states[40]= 0.000112
Saving checkpoint... 
Iteration: 111426678, states[0] = -85.875483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124291613, states[0] = -87.672511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137206257, states[0] = -9.032036, states[40]= 0.003653
Saving checkpoint... 
Iteration: 150150506, states[0] = -87.753983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163081572, states[0] = -78.241674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175967951, states[0] = -87.719801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188112711, states[0] = -87.652094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200870346, states[0] = -14.506427, states[40]= 0.002208
Saving checkpoint... 
Iteration: 213340626, states[0] = 13.496993, states[40]= 0.008677
Saving checkpoint... 
Iteration: 222730617, states[0] = -57.617751, states[40]= 0.000012
Saving checkpoint... 
Iteration: 232737114, states[0] = -70.474726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 245274950, states[0] = -87.656921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258307163, states[0] = -87.756064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271116222, states[0] = -87.693134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283854415, states[0] = -4.098784, states[40]= 0.005148
Saving checkpoint... 
Iteration: 296519334, states[0] = -3.532607, states[40]= 0.005309
Saving checkpoint... 
Iteration: 309230357, states[0] = -72.162630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322299732, states[0] = -87.753642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334162302, states[0] = 13.221889, states[40]= 0.008604
Saving checkpoint... 
Iteration: 346550931, states[0] = -56.622881, states[40]= 0.000014
Saving checkpoint... 
Iteration: 359341167, states[0] = 1.906276, states[40]= 0.006608
Saving checkpoint... 
Iteration: 372417097, states[0] = -87.604084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383959740, states[0] = -87.752339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396773083, states[0] = -87.701596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409575061, states[0] = -87.555527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421808712, states[0] = 19.760431, states[40]= 0.014487
Saving checkpoint... 
Iteration: 434896880, states[0] = -86.839715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447522527, states[0] = -29.629934, states[40]= 0.000538
Saving checkpoint... 
Iteration: 460337725, states[0] = -5.263340, states[40]= 0.004804
Saving checkpoint... 
Iteration: 473159781, states[0] = 4.866424, states[40]= 0.007133
Saving checkpoint... 
Iteration: 486145793, states[0] = 14.057647, states[40]= 0.008838
Saving checkpoint... 
Iteration: 499021472, states[0] = -35.592503, states[40]= 0.000280
Saving checkpoint... 
Iteration: 511802378, states[0] = 18.402217, states[40]= 0.011716
Saving checkpoint... 
Iteration: 524600201, states[0] = -87.720727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537715232, states[0] = -84.390088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550852440, states[0] = -39.676096, states[40]= 0.000166
Saving checkpoint... 
Iteration: 563962449, states[0] = 19.115866, states[40]= 0.012927
Saving checkpoint... 
Iteration: 576752854, states[0] = -87.694494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587652193, states[0] = 1.407818, states[40]= 0.006509
Saving checkpoint... 
Iteration: 599231412, states[0] = -87.623370, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758_0_r395133575_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_333-conf_758_0_r395133575_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.618069
     * GNaL_b in INaL: 0.004725
     * Gto_b in Ito: 0.073691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033464
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.180768
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.023762
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023143
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 599231412
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.623370 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 609149490, states[0] = 1.931004, states[40]= 0.006613
Saving checkpoint... 
Iteration: 615318750, states[0] = -1.268616, states[40]= 0.005909
Saving checkpoint... 
Iteration: 625914538, states[0] = -87.694208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636825742, states[0] = -13.029826, states[40]= 0.002550
Saving checkpoint... 
Iteration: 649337422, states[0] = -32.181852, states[40]= 0.000413
Saving checkpoint... 
Iteration: 660419765, states[0] = -87.720106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669244325, states[0] = -87.696634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680947762, states[0] = 20.583751, states[40]= 0.017487
Saving checkpoint... 
Iteration: 691206230, states[0] = -87.149575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701212126, states[0] = -87.547980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712710826, states[0] = -87.545267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724318715, states[0] = -15.575549, states[40]= 0.001987
Saving checkpoint... 
Iteration: 736011987, states[0] = -56.628652, states[40]= 0.000014
Saving checkpoint... 
Iteration: 747683605, states[0] = -66.794733, states[40]= 0.000003
Saving checkpoint... 
Iteration: 759847931, states[0] = -64.815127, states[40]= 0.000004
Saving checkpoint... 
Iteration: 772408200, states[0] = -87.718862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784946220, states[0] = 15.898793, states[40]= 0.009562
Saving checkpoint... 
Iteration: 796562404, states[0] = -87.688349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808704140, states[0] = -87.583260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820907795, states[0] = -87.731003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833618079, states[0] = 9.290114, states[40]= 0.007828
Saving checkpoint... 
Iteration: 845187406, states[0] = -86.267098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857022383, states[0] = -87.055150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868736019, states[0] = -87.730072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881689288, states[0] = -87.366866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893354393, states[0] = -87.336426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905814006, states[0] = -35.423574, states[40]= 0.000285
Saving checkpoint... 
Iteration: 918322163, states[0] = -49.146470, states[40]= 0.000044
Saving checkpoint... 
Iteration: 929958305, states[0] = -6.374889, states[40]= 0.004466
Saving checkpoint... 
Iteration: 942836527, states[0] = -77.543418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955305275, states[0] = -29.918891, states[40]= 0.000523
Saving checkpoint... 
Iteration: 966634068, states[0] = -24.900533, states[40]= 0.000832
Saving checkpoint... 
Iteration: 979047844, states[0] = -87.699803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991604952, states[0] = 7.276035, states[40]= 0.007512
Saving checkpoint... 
Iteration: 1002866008, states[0] = -87.656552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015324135, states[0] = -67.928173, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1027879003, states[0] = -87.707952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038708219, states[0] = -87.698721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051286114, states[0] = -15.717655, states[40]= 0.001959
Saving checkpoint... 
Iteration: 1063997996, states[0] = -85.860006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076329918, states[0] = -85.760715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088681721, states[0] = -87.619247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101042199, states[0] = -87.719121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112915440, states[0] = 14.682508, states[40]= 0.009043
Saving checkpoint... 
Iteration: 1125333906, states[0] = -87.485639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137910619, states[0] = 16.075458, states[40]= 0.009653
Saving checkpoint... 
Iteration: 1149894556, states[0] = 23.755124, states[40]= 0.051355
Saving checkpoint... 
Iteration: 1162410416, states[0] = 14.727377, states[40]= 0.009060
Saving checkpoint... 
Iteration: 1174938494, states[0] = -12.885598, states[40]= 0.002586
Saving checkpoint... 
Iteration: 1186563584, states[0] = 20.716181, states[40]= 0.018113
Saving checkpoint... 
Iteration: 1199070169, states[0] = 16.651935, states[40]= 0.010002
Saving checkpoint... 
Iteration: 1211628651, states[0] = -52.883837, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1223056305, states[0] = 22.442774, states[40]= 0.032125
Saving checkpoint... 
Iteration: 1234689749, states[0] = -87.702015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246284947, states[0] = -42.654407, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1255117008, states[0] = -42.093800, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1265310201, states[0] = -85.247469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277526031, states[0] = -87.722997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289961743, states[0] = -65.098928, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1301605108, states[0] = -31.576980, states[40]= 0.000441
Saving checkpoint... 
Iteration: 1313651747, states[0] = -87.560914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326590880, states[0] = -14.188873, states[40]= 0.002278
Saving checkpoint... 
Iteration: 1338716235, states[0] = 20.140661, states[40]= 0.015698
Saving checkpoint... 
Iteration: 1350903709, states[0] = 6.201339, states[40]= 0.007345
Saving checkpoint... 
Iteration: 1363469609, states[0] = -86.531229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375751609, states[0] = -12.686758, states[40]= 0.002635
Saving checkpoint... 
Iteration: 1388396676, states[0] = 8.739811, states[40]= 0.007740
Saving checkpoint... 
Iteration: 1401062274, states[0] = 8.592530, states[40]= 0.007716
Saving checkpoint... 
Iteration: 1413043599, states[0] = 19.419158, states[40]= 0.013594
Saving checkpoint... 
Iteration: 1425686484, states[0] = -87.745193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438346542, states[0] = -87.731546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450643288, states[0] = -87.606856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463223422, states[0] = 8.067576, states[40]= 0.007634
Saving checkpoint... 
Iteration: 1475909407, states[0] = -14.373924, states[40]= 0.002237
Saving checkpoint... 
Iteration: 1487881067, states[0] = 12.692220, states[40]= 0.008474
Saving checkpoint... 
Iteration: 1498546958, states[0] = 12.500446, states[40]= 0.008430
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.630913
 - CaMKt in component CaMK (millimolar): 0.040998
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.117215
 - nass in component intracellular_ions (millimolar): 7.117360
 - ki in component intracellular_ions (millimolar): 144.804540
 - kss in component intracellular_ions (millimolar): 144.804508
 - cansr in component intracellular_ions (millimolar): 1.613918
 - cajsr in component intracellular_ions (millimolar): 1.189748
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007529
 - hf in component INa (dimensionless): 0.689496
 - hs in component INa (dimensionless): 0.689284
 - j in component INa (dimensionless): 0.681449
 - hsp in component INa (dimensionless): 0.444096
 - jp in component INa (dimensionless): 0.659404
 - mL in component INaL (dimensionless): 0.000197
 - hL in component INaL (dimensionless): 0.306510
 - hLp in component INaL (dimensionless): 0.144366
 - a in component Ito (dimensionless): 0.001018
 - iF in component Ito (dimensionless): 0.999534
 - iS in component Ito (dimensionless): 0.183548
 - ap in component Ito (dimensionless): 0.000519
 - iFp in component Ito (dimensionless): 0.999534
 - iSp in component Ito (dimensionless): 0.223416
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.810764
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.968468
 - jca in component ICaL (dimensionless): 0.951965
 - ffp in component ICaL (dimensionless): 0.999908
 - fcafp in component ICaL (dimensionless): 0.999994
 - nca in component ICaL (dimensionless): 0.009442
 - xrf in component IKr (dimensionless): 0.024738
 - xrs in component IKr (dimensionless): 0.786825
 - xs1 in component IKs (dimensionless): 0.447766
 - xs2 in component IKs (dimensionless): 0.000926
 - xk1 in component IK1 (dimensionless): 0.996828
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:10:58 (9364): called boinc_finish(0)

</stderr_txt>
]]>


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