𝕏

Task 55004483

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1
Workunit 26118038
Created 27 Jun 2024, 17:53:49 UTC
Sent 27 Jun 2024, 23:15:51 UTC
Report deadline 30 Jun 2024, 23:15:51 UTC
Received 28 Jun 2024, 4:20:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 58 min 24 sec
CPU time 1 hours 58 min 24 sec
Validate state Valid
Credit 43.17
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.62 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.618069
     * GNaL_b in INaL: 0.004725
     * Gto_b in Ito: 0.073691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033464
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.180768
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.023762
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023143
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13549223, states[0] = 33.675723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26114783, states[0] = -94.293020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39833948, states[0] = -94.316448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51657494, states[0] = -94.318171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 65064929, states[0] = -94.308134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77761757, states[0] = -94.327272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90379649, states[0] = -94.152209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103949988, states[0] = -94.257918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116704066, states[0] = -94.341214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130149362, states[0] = -94.345184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142575617, states[0] = 23.190992, states[40]= 0.000002
Saving checkpoint... 
Iteration: 155492768, states[0] = -94.353060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167779842, states[0] = -94.343364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180023505, states[0] = 34.168349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192860312, states[0] = -94.357934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204397225, states[0] = -94.200744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217994395, states[0] = -94.302200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229935042, states[0] = -94.252039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243782109, states[0] = -94.358338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255702500, states[0] = -94.355707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266056593, states[0] = -94.330698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278165947, states[0] = -94.352452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290516697, states[0] = -94.352432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303696347, states[0] = -94.354571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316152876, states[0] = -94.347013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329463085, states[0] = -94.353629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342058214, states[0] = 29.030739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354482197, states[0] = -94.292195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367882268, states[0] = -94.172275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380999975, states[0] = -94.335003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394085206, states[0] = -94.348098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406947079, states[0] = -94.261859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420041137, states[0] = 33.189715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432521320, states[0] = -94.313548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445855826, states[0] = -94.112850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458187866, states[0] = -94.351184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471558151, states[0] = -94.327593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484202512, states[0] = -94.342194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497992157, states[0] = -94.333056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509900883, states[0] = -94.335343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523646585, states[0] = -7.756794, states[40]= 0.000623
Saving checkpoint... 
Iteration: 535797243, states[0] = -93.907002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549378014, states[0] = -94.160620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561788095, states[0] = -94.352804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575300249, states[0] = -94.352578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587909126, states[0] = -94.333672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601294612, states[0] = -94.336927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614092580, states[0] = -94.334621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627312185, states[0] = -93.969912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639856840, states[0] = -94.350835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652254441, states[0] = -94.337328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664856704, states[0] = -94.110974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678323207, states[0] = -94.010549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691152233, states[0] = -94.340195, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.618069
     * GNaL_b in INaL: 0.004725
     * Gto_b in Ito: 0.073691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033464
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.180768
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.023762
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023143
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 691152233
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.340195 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 705018857, states[0] = 33.564686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717001417, states[0] = 39.695273, states[40]= 2.151696
Saving checkpoint... 
Iteration: 730959947, states[0] = -94.267845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743187714, states[0] = -94.345948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757076813, states[0] = -94.341751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768718970, states[0] = -94.347379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780889974, states[0] = -94.347531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794404839, states[0] = -94.346898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806851186, states[0] = -94.331375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820549408, states[0] = 31.473439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832739911, states[0] = -70.229552, states[40]= 0.000034
Saving checkpoint... 
Iteration: 846160692, states[0] = -16.542298, states[40]= 0.000984
Saving checkpoint... 
Iteration: 859355116, states[0] = -94.330290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871883344, states[0] = -94.164957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885317275, states[0] = -93.984864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897896655, states[0] = -94.345216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911789077, states[0] = -94.331410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924662620, states[0] = -94.340346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938461739, states[0] = -94.342525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951335968, states[0] = -94.047861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963243470, states[0] = -75.740429, states[40]= 0.000016
Saving checkpoint... 
Iteration: 974730016, states[0] = -94.332232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987494294, states[0] = -94.288542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999628208, states[0] = -94.334459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011939027, states[0] = -94.341905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025138015, states[0] = -94.335465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037601183, states[0] = -94.335699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050527244, states[0] = -94.304931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063356102, states[0] = -94.326509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076942352, states[0] = -94.323757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089569084, states[0] = -94.319679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102261123, states[0] = -94.328841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114419177, states[0] = -94.323726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128312085, states[0] = -93.960081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142121197, states[0] = -94.330692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155984655, states[0] = -94.337762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167951186, states[0] = -94.338664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181317785, states[0] = -94.341403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193791324, states[0] = -94.326164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207206960, states[0] = -94.328771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219732430, states[0] = -61.626008, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1233002624, states[0] = 23.682497, states[40]= 1.464170
Saving checkpoint... 
Iteration: 1245271040, states[0] = -93.753265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258022129, states[0] = -94.334560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269158950, states[0] = -15.486316, states[40]= 0.000859
Saving checkpoint... 
Iteration: 1280380540, states[0] = -94.338594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291679621, states[0] = -25.522701, states[40]= 0.004620
Saving checkpoint... 
Iteration: 1302663263, states[0] = -94.333479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1315920009, states[0] = -94.214321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328843386, states[0] = -94.322029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342106241, states[0] = -94.329927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1354589967, states[0] = 17.587942, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1368208209, states[0] = -41.935344, states[40]= 0.001719


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_3000-conf_758_1_r1552119062_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.618069
     * GNaL_b in INaL: 0.004725
     * Gto_b in Ito: 0.073691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033464
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.180768
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.023762
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023143
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1368208209
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -41.935344 (After loading)
 - states[40]: 0.001719 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1382064467, states[0] = -94.312894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393888463, states[0] = -94.164659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407767169, states[0] = -94.337085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419652941, states[0] = -94.330174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431734968, states[0] = -94.335862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445308156, states[0] = -94.336605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457871005, states[0] = -94.318818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470370758, states[0] = -94.128491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484271108, states[0] = -94.335734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496472443, states[0] = -94.331927, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.190409
 - CaMKt in component CaMK (millimolar): 0.004450
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 8.104011
 - nass in component intracellular_ions (millimolar): 8.104178
 - ki in component intracellular_ions (millimolar): 143.604189
 - kss in component intracellular_ions (millimolar): 143.604171
 - cansr in component intracellular_ions (millimolar): 1.960488
 - cajsr in component intracellular_ions (millimolar): 1.962690
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003888
 - hf in component INa (dimensionless): 0.867096
 - hs in component INa (dimensionless): 0.867097
 - j in component INa (dimensionless): 0.867104
 - hsp in component INa (dimensionless): 0.701997
 - jp in component INa (dimensionless): 0.867107
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710071
 - hLp in component INaL (dimensionless): 0.512430
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.965432
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.982156
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.986366
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005222
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.032619
 - xs1 in component IKs (dimensionless): 0.090194
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997518
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:17:42 (15700): called boinc_finish(0)

</stderr_txt>
]]>


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