𝕏

Task 55004221

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1
Workunit 26117907
Created 27 Jun 2024, 17:53:44 UTC
Sent 27 Jun 2024, 23:15:51 UTC
Report deadline 30 Jun 2024, 23:15:51 UTC
Received 28 Jun 2024, 8:23:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 53 min 47 sec
CPU time 1 hours 53 min 47 sec
Validate state Valid
Credit 42.51
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.773750
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.074576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032065
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.158863
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 68.869989
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018272
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13722271, states[0] = -93.935874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25404738, states[0] = -93.879021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37962191, states[0] = -93.841866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50214829, states[0] = -91.169583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63892635, states[0] = -93.832352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77421149, states[0] = -93.843364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91308166, states[0] = -93.847226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103827664, states[0] = -93.833292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116932009, states[0] = -93.862709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129271921, states[0] = -93.848898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142154787, states[0] = -37.627664, states[40]= 0.001039
Saving checkpoint... 
Iteration: 155189117, states[0] = -93.852183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168214765, states[0] = -91.058797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180985701, states[0] = -93.860729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192099062, states[0] = 3.868600, states[40]= 0.003116
Saving checkpoint... 
Iteration: 203537026, states[0] = -93.840432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215158437, states[0] = -93.853402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226882978, states[0] = -93.864618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237898788, states[0] = -93.832174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251785095, states[0] = -93.834371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264824558, states[0] = -93.866165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278645862, states[0] = -93.862049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290545813, states[0] = -93.843725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304363438, states[0] = -93.694924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317748123, states[0] = -93.835006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331490303, states[0] = -93.841488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343253421, states[0] = -93.849376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356982352, states[0] = -93.860515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369639014, states[0] = -93.837405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381333028, states[0] = -93.846394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394307340, states[0] = -93.564512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406664785, states[0] = -93.863344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418789874, states[0] = -93.866356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432678078, states[0] = -93.864168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445525754, states[0] = -93.840197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459476326, states[0] = -93.841588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472842250, states[0] = -93.865250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486917158, states[0] = -93.862796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500226130, states[0] = -93.089537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514035228, states[0] = 28.818281, states[40]= 0.000151
Saving checkpoint... 
Iteration: 527515364, states[0] = -93.840290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541759876, states[0] = -93.834208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555311818, states[0] = -93.846717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569162417, states[0] = -93.852406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582466148, states[0] = -93.807060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594559679, states[0] = -93.846842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607712655, states[0] = -93.835087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620914667, states[0] = -93.862563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633808561, states[0] = -93.832967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645005741, states[0] = -93.858832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658134286, states[0] = -21.886944, states[40]= 0.001788
Saving checkpoint... 
Iteration: 671899176, states[0] = -93.831123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686380754, states[0] = -93.721589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700576600, states[0] = -93.850597, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.773750
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.074576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032065
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.158863
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 68.869989
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018272
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 700576600
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.850597 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 715113055, states[0] = -93.854096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728924798, states[0] = -93.861919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743455055, states[0] = -93.841534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755785766, states[0] = -93.833138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770090228, states[0] = 8.195495, states[40]= 0.002428
Saving checkpoint... 
Iteration: 783796136, states[0] = -93.832855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797320775, states[0] = -93.845809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810837385, states[0] = -93.864549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825249402, states[0] = -93.848354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839256177, states[0] = -93.848063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852614730, states[0] = -93.856985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866231425, states[0] = -93.207594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879330536, states[0] = -93.845266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891762071, states[0] = -93.833306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905526552, states[0] = -93.839052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917579127, states[0] = -93.837594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931573642, states[0] = -93.837704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946055677, states[0] = 22.120398, states[40]= 0.000466
Saving checkpoint... 
Iteration: 960459737, states[0] = -93.801866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974987267, states[0] = -93.858805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989400516, states[0] = -93.842645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003661984, states[0] = -93.835300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018137134, states[0] = -24.110186, states[40]= 0.001999
Saving checkpoint... 
Iteration: 1032474227, states[0] = -93.810986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046765508, states[0] = -93.864961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061068252, states[0] = -93.855152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075359268, states[0] = -93.843800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089748745, states[0] = -93.833110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104223220, states[0] = -92.935261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118823835, states[0] = -93.864109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133772577, states[0] = -93.832491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148385725, states[0] = -93.727555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162106400, states[0] = -0.256924, states[40]= 0.003435
Saving checkpoint... 
Iteration: 1174442381, states[0] = -93.788384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188459718, states[0] = -93.801296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200010931, states[0] = 31.519089, states[40]= 0.042045
Saving checkpoint... 
Iteration: 1211618998, states[0] = -93.835848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223173660, states[0] = -93.850355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236076074, states[0] = 14.304633, states[40]= 0.001361
Saving checkpoint... 
Iteration: 1249713612, states[0] = -93.833497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264838011, states[0] = -93.863429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277430118, states[0] = -93.841001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292635956, states[0] = -93.858569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304794496, states[0] = -93.864148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319399265, states[0] = -93.841880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333510294, states[0] = -93.838467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346938192, states[0] = -93.859896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360526783, states[0] = -93.834878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374094065, states[0] = 6.382324, states[40]= 0.002743
Saving checkpoint... 
Iteration: 1387862324, states[0] = -93.830065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401138576, states[0] = -93.851358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414766255, states[0] = -93.864065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428383633, states[0] = -93.723922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442697595, states[0] = -93.862705, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_658_1_r325860262_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.773750
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.074576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032065
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.158863
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 68.869989
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018272
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1442697595
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.862705 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1456017103, states[0] = 32.025963, states[40]= 0.004961
Saving checkpoint... 
Iteration: 1468900856, states[0] = -93.861000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481809328, states[0] = -93.830880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494935668, states[0] = -93.859634, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.703314
 - CaMKt in component CaMK (millimolar): 0.002050
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.791125
 - nass in component intracellular_ions (millimolar): 6.791247
 - ki in component intracellular_ions (millimolar): 145.069080
 - kss in component intracellular_ions (millimolar): 145.069070
 - cansr in component intracellular_ions (millimolar): 1.823491
 - cajsr in component intracellular_ions (millimolar): 1.823328
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004084
 - hf in component INa (dimensionless): 0.857599
 - hs in component INa (dimensionless): 0.857600
 - j in component INa (dimensionless): 0.857604
 - hsp in component INa (dimensionless): 0.684985
 - jp in component INa (dimensionless): 0.857606
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.696472
 - hLp in component INaL (dimensionless): 0.500137
 - a in component Ito (dimensionless): 0.000676
 - iF in component Ito (dimensionless): 0.999839
 - iS in component Ito (dimensionless): 0.991378
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999839
 - iSp in component Ito (dimensionless): 0.996522
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996536
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005166
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008251
 - xs1 in component IKs (dimensionless): 0.040751
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997635
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:42:59 (16176): called boinc_finish(0)

</stderr_txt>
]]>


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