𝕏

Task 54999094

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_4000-conf_353_1
Workunit 26115393
Created 27 Jun 2024, 17:51:26 UTC
Sent 27 Jun 2024, 23:01:47 UTC
Report deadline 30 Jun 2024, 23:01:47 UTC
Received 28 Jun 2024, 3:11:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241398
Run time 2 hours 54 min 17 sec
CPU time 2 hours 53 min 59 sec
Validate state Valid
Credit 43.26
Device peak FLOPS 1.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.68 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_4000-conf_353.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_4000-conf_353_1_r1046428776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_4000-conf_353_1_r1046428776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.502399
     * GNaL_b in INaL: 0.006025
     * Gto_b in Ito: 0.096799
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030865
     * GKs_b in IKs: 0.001825
     * GK1_b in IK1: 0.152475
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 73.729630
     * GKb_b in IKb: 0.003882
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032563
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9599144, states[0] = -94.173274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19155693, states[0] = -94.165384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28575256, states[0] = -94.131760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38049846, states[0] = 32.636203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47487597, states[0] = -94.168434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56999165, states[0] = -94.194890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66473653, states[0] = -94.091942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76041359, states[0] = 33.261985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85468573, states[0] = -94.193880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95080606, states[0] = -94.212106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104495673, states[0] = -94.136406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113905315, states[0] = -94.192257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123417230, states[0] = -94.206091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132824821, states[0] = -94.227510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142308728, states[0] = -93.640186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151860204, states[0] = -94.198097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161230526, states[0] = -94.216597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170578372, states[0] = -94.197268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179966309, states[0] = -94.197612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189554244, states[0] = -94.206699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199025610, states[0] = -94.225963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208571551, states[0] = -94.195325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218203725, states[0] = -26.876962, states[40]= 0.007878
Saving checkpoint... 
Iteration: 227543632, states[0] = -94.207270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237091286, states[0] = -94.223424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246677531, states[0] = -94.222867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256241929, states[0] = -47.853527, states[40]= 0.000999
Saving checkpoint... 
Iteration: 265774558, states[0] = -94.201426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275282999, states[0] = -94.215517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284699242, states[0] = -94.225187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294328798, states[0] = -93.757714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303888524, states[0] = -94.198833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313416514, states[0] = -94.210418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322947465, states[0] = -94.228072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332466559, states[0] = -94.116653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342025120, states[0] = 32.774106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351525673, states[0] = -94.206599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361196491, states[0] = -94.217864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 370618138, states[0] = -94.209837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379891491, states[0] = -94.197840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389352979, states[0] = -94.211617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398726480, states[0] = -94.226217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408275846, states[0] = -79.781411, states[40]= 0.000008
Saving checkpoint... 
Iteration: 417822168, states[0] = -94.198645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427412616, states[0] = -94.209105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436882052, states[0] = -94.228336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446338318, states[0] = -93.800458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455936493, states[0] = -94.196082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465469377, states[0] = -94.206805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475064507, states[0] = -94.221761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484723572, states[0] = -94.224887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494200409, states[0] = -25.802269, states[40]= 0.007809
Saving checkpoint... 
Iteration: 503841890, states[0] = -94.197148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513333606, states[0] = -94.210695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522820670, states[0] = -94.227761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 532553037, states[0] = -94.183263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542088804, states[0] = 20.127091, states[40]= 0.000005
Saving checkpoint... 
Iteration: 551609262, states[0] = -94.201723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561249812, states[0] = -94.213182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570685373, states[0] = -94.219961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580079320, states[0] = 23.471694, states[40]= 0.000002
Saving checkpoint... 
Iteration: 589593222, states[0] = -94.201648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599137282, states[0] = -94.217174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608606292, states[0] = -94.203396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 618088686, states[0] = 20.170035, states[40]= 0.000005
Saving checkpoint... 
Iteration: 627561726, states[0] = -94.202005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637133930, states[0] = -94.216817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646693076, states[0] = -94.219898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656209076, states[0] = -28.900515, states[40]= 0.007465
Saving checkpoint... 
Iteration: 665936950, states[0] = -94.193336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 675479670, states[0] = -94.203753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684946886, states[0] = -94.223416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694608510, states[0] = -94.202936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704084964, states[0] = 21.500587, states[40]= 0.000004
Saving checkpoint... 
Iteration: 713729484, states[0] = -94.196723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723191900, states[0] = -94.213347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732683066, states[0] = -94.217556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742195376, states[0] = -24.192322, states[40]= 0.007301
Saving checkpoint... 
Iteration: 751697521, states[0] = -94.196952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761217089, states[0] = -94.211852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770855294, states[0] = -94.224393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780482140, states[0] = -94.127937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789912282, states[0] = -94.192138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799496175, states[0] = -94.201640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809054480, states[0] = -94.217817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818740357, states[0] = -94.221669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828345364, states[0] = -93.825648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837721559, states[0] = -94.195283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847132441, states[0] = -94.214143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856592415, states[0] = -94.195686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866129535, states[0] = 4.983154, states[40]= 0.000207
Saving checkpoint... 
Iteration: 875684142, states[0] = -94.195646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885330918, states[0] = -94.205945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894924530, states[0] = -94.221359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904403901, states[0] = -94.005666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913903806, states[0] = -94.190668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923335641, states[0] = -94.205280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932890131, states[0] = -94.221720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942357530, states[0] = -93.871497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952072525, states[0] = 25.747320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961634551, states[0] = -94.195734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971171124, states[0] = -94.210954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980761216, states[0] = -94.220589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990360027, states[0] = -93.879842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999961819, states[0] = -94.188572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009572020, states[0] = -94.196742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019252102, states[0] = -94.207129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028926691, states[0] = -94.219556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038404316, states[0] = -94.004827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047825569, states[0] = -94.190370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057347973, states[0] = -94.203102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066913095, states[0] = -94.219438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076403314, states[0] = -94.002085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085981069, states[0] = -94.187150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095450969, states[0] = -94.199173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104940538, states[0] = -94.218153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114437907, states[0] = -94.067088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123975382, states[0] = -94.186744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133544066, states[0] = -94.195905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143006813, states[0] = -94.215344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152380222, states[0] = -93.942287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161935617, states[0] = -94.186894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171802590, states[0] = -94.189209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181280678, states[0] = -94.203937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190710240, states[0] = -94.214585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200236377, states[0] = -43.892235, states[40]= 0.001689
Saving checkpoint... 
Iteration: 1209882645, states[0] = -94.187188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219650485, states[0] = -94.191977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229307884, states[0] = -94.202301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238815831, states[0] = -94.218426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248348749, states[0] = -93.833832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257985887, states[0] = -94.184831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267347855, states[0] = -94.200370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1276754328, states[0] = -94.216443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286210764, states[0] = -29.566540, states[40]= 0.007230
Saving checkpoint... 
Iteration: 1295747300, states[0] = -94.188747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305405252, states[0] = -94.197913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314834030, states[0] = -94.217465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324431750, states[0] = -94.054286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333991452, states[0] = -94.183753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343475115, states[0] = -94.195191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352854909, states[0] = -94.216828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362291163, states[0] = -93.225701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371927170, states[0] = -94.184297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381462631, states[0] = -94.195082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391006838, states[0] = -94.212115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400378946, states[0] = -93.935299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409946526, states[0] = -94.183478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419501429, states[0] = -94.193408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429084695, states[0] = -94.208525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438667731, states[0] = -94.206189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448119795, states[0] = 8.660794, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1457566232, states[0] = -94.191065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466976319, states[0] = -94.212248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476730421, states[0] = -94.212474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486320427, states[0] = -93.698815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496048048, states[0] = 32.107662, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.057425
 - CaMKt in component CaMK (millimolar): 0.002791
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.725318
 - nass in component intracellular_ions (millimolar): 7.725481
 - ki in component intracellular_ions (millimolar): 144.039461
 - kss in component intracellular_ions (millimolar): 144.039444
 - cansr in component intracellular_ions (millimolar): 1.888686
 - cajsr in component intracellular_ions (millimolar): 1.890541
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003940
 - hf in component INa (dimensionless): 0.864558
 - hs in component INa (dimensionless): 0.864558
 - j in component INa (dimensionless): 0.864562
 - hsp in component INa (dimensionless): 0.697403
 - jp in component INa (dimensionless): 0.864564
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706373
 - hLp in component INaL (dimensionless): 0.511580
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.989895
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.995832
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994653
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004981
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009366
 - xs1 in component IKs (dimensionless): 0.055025
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997550
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:17:54 (19526): called boinc_finish(0)

</stderr_txt>
]]>


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