𝕏

Task 54997489

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_452_1
Workunit 26114614
Created 27 Jun 2024, 17:50:44 UTC
Sent 27 Jun 2024, 22:55:54 UTC
Report deadline 1 Jul 2024, 1:48:42 UTC
Received 28 Jun 2024, 3:22:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 27 min 43 sec
CPU time 2 hours 26 min 13 sec
Validate state Valid
Credit 47.66
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.47 MB
Peak swap size 2.35 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_452.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_452_1_r534179332_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_452_1_r534179332_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 113.047854
     * GNaL_b in INaL: 0.006893
     * Gto_b in Ito: 0.096137
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033023
     * GKs_b in IKs: 0.001802
     * GK1_b in IK1: 0.043925
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 73.221069
     * GKb_b in IKb: 0.003879
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020092
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10681580, states[0] = -79.250470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21508551, states[0] = 26.671996, states[40]= 0.078286
Saving checkpoint... 
Iteration: 32360075, states[0] = -91.526205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43203861, states[0] = -83.443998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54047506, states[0] = 18.677397, states[40]= 0.002112
Saving checkpoint... 
Iteration: 64859435, states[0] = -91.376144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75625606, states[0] = -36.098230, states[40]= 0.000554
Saving checkpoint... 
Iteration: 86435143, states[0] = -91.539380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97258758, states[0] = -90.154290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108364184, states[0] = -91.338698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119519289, states[0] = 27.031549, states[40]= 0.002934
Saving checkpoint... 
Iteration: 130719622, states[0] = -86.447283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141890143, states[0] = -91.410486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153076914, states[0] = 5.894417, states[40]= 0.004248
Saving checkpoint... 
Iteration: 164094476, states[0] = -5.987035, states[40]= 0.003430
Saving checkpoint... 
Iteration: 175142849, states[0] = -51.578253, states[40]= 0.000066
Saving checkpoint... 
Iteration: 186320860, states[0] = -91.093025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197506300, states[0] = 27.522733, states[40]= 0.170007
Saving checkpoint... 
Iteration: 208682491, states[0] = -75.411559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219900597, states[0] = -91.430031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231063675, states[0] = 12.323537, states[40]= 0.003399
Saving checkpoint... 
Iteration: 242229204, states[0] = -87.898727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253415312, states[0] = -91.462246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264591361, states[0] = -3.401069, states[40]= 0.003903
Saving checkpoint... 
Iteration: 275792358, states[0] = -90.829375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286966293, states[0] = -91.537197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298135403, states[0] = -44.864580, states[40]= 0.000182
Saving checkpoint... 
Iteration: 309369749, states[0] = -91.336466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321052269, states[0] = 17.031710, states[40]= 0.002492
Saving checkpoint... 
Iteration: 332722952, states[0] = -86.981965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344382495, states[0] = -91.378713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356072521, states[0] = 8.192493, states[40]= 0.004025
Saving checkpoint... 
Iteration: 367751792, states[0] = -89.802401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379452888, states[0] = -91.521613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391193602, states[0] = -79.549398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402904422, states[0] = -91.437380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414522558, states[0] = 26.569057, states[40]= 0.001658
Saving checkpoint... 
Iteration: 426211019, states[0] = -84.597457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437914446, states[0] = -91.459202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449613467, states[0] = -24.290264, states[40]= 0.001150
Saving checkpoint... 
Iteration: 461311132, states[0] = -91.015540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473016621, states[0] = 27.247380, states[40]= 0.005890
Saving checkpoint... 
Iteration: 484734644, states[0] = -88.530264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496445462, states[0] = -91.511383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508157050, states[0] = -62.336029, states[40]= 0.000010
Saving checkpoint... 
Iteration: 519848563, states[0] = -91.247789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531530639, states[0] = 24.619022, states[40]= 0.001292
Saving checkpoint... 
Iteration: 543252786, states[0] = -89.850085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554961965, states[0] = -91.531188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566645853, states[0] = -54.086263, states[40]= 0.000044
Saving checkpoint... 
Iteration: 578152826, states[0] = -59.446035, states[40]= 0.000017
Saving checkpoint... 
Iteration: 589862246, states[0] = -91.306608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601558967, states[0] = 14.336137, states[40]= 0.003023
Saving checkpoint... 
Iteration: 613242103, states[0] = -89.197552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624961414, states[0] = -91.530237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636669107, states[0] = -69.307192, states[40]= 0.000003
Saving checkpoint... 
Iteration: 648371861, states[0] = -91.342172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660075626, states[0] = 6.599315, states[40]= 0.004192
Saving checkpoint... 
Iteration: 671779659, states[0] = -90.641821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683473776, states[0] = -91.542225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695264509, states[0] = -90.295507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706981030, states[0] = -91.548296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718697870, states[0] = -80.949701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730441739, states[0] = -91.504983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742147252, states[0] = -55.220232, states[40]= 0.000036
Saving checkpoint... 
Iteration: 753868775, states[0] = -91.330586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765571418, states[0] = 8.739328, states[40]= 0.003957
Saving checkpoint... 
Iteration: 777284101, states[0] = -90.713729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788976943, states[0] = -91.544482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800719755, states[0] = -86.424915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812470744, states[0] = -91.538769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824216735, states[0] = -85.845600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835939403, states[0] = -91.501039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847642272, states[0] = -51.054830, states[40]= 0.000072
Saving checkpoint... 
Iteration: 859372440, states[0] = -91.343115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871086357, states[0] = 0.240352, states[40]= 0.004308
Saving checkpoint... 
Iteration: 882831585, states[0] = -91.155991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894555961, states[0] = 15.568108, states[40]= 0.002782
Saving checkpoint... 
Iteration: 906273980, states[0] = -90.531661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917999793, states[0] = -91.560167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929720101, states[0] = -86.486691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941378529, states[0] = -91.363133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953136845, states[0] = -46.189345, states[40]= 0.000151
Saving checkpoint... 
Iteration: 964817680, states[0] = -91.063750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976528067, states[0] = 25.331832, states[40]= 0.001260
Saving checkpoint... 
Iteration: 988135771, states[0] = -45.201031, states[40]= 0.000174
Saving checkpoint... 
Iteration: 999867823, states[0] = -91.325830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011605282, states[0] = -16.278742, states[40]= 0.001519
Saving checkpoint... 
Iteration: 1023301453, states[0] = -90.925199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035017028, states[0] = 27.230456, states[40]= 0.005245
Saving checkpoint... 
Iteration: 1046706725, states[0] = -83.517872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058417524, states[0] = -91.462259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070128103, states[0] = -38.067905, states[40]= 0.000444
Saving checkpoint... 
Iteration: 1081835555, states[0] = -91.177892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093542287, states[0] = 20.773486, states[40]= 0.001809
Saving checkpoint... 
Iteration: 1105203547, states[0] = -82.648817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116917068, states[0] = -91.461056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128639120, states[0] = -48.259212, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1140375709, states[0] = -91.352841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152108587, states[0] = -19.553225, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1163845148, states[0] = -91.227984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175579062, states[0] = 4.726242, states[40]= 0.004325
Saving checkpoint... 
Iteration: 1187273800, states[0] = -90.526246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199005467, states[0] = 28.361157, states[40]= 0.224148
Saving checkpoint... 
Iteration: 1210731602, states[0] = -88.186941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222432883, states[0] = -91.488974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234174547, states[0] = -71.952296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1245916124, states[0] = -91.458511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257608613, states[0] = -19.578410, states[40]= 0.001261
Saving checkpoint... 
Iteration: 1269306355, states[0] = -90.970186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280818383, states[0] = -91.067223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292538575, states[0] = 22.079618, states[40]= 0.001605
Saving checkpoint... 
Iteration: 1304226177, states[0] = -87.472655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315960171, states[0] = -91.525375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327639472, states[0] = -48.575294, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1339311444, states[0] = -91.013446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351007843, states[0] = 26.917951, states[40]= 0.101247
Saving checkpoint... 
Iteration: 1362670464, states[0] = -69.988945, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374367540, states[0] = -91.322861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385957967, states[0] = -91.522538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397650952, states[0] = -58.075215, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1409344891, states[0] = -91.225443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421061367, states[0] = 13.325629, states[40]= 0.003216
Saving checkpoint... 
Iteration: 1432770296, states[0] = -90.445864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444437133, states[0] = -91.494536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456079554, states[0] = 4.447700, states[40]= 0.004338
Saving checkpoint... 
Iteration: 1467779168, states[0] = -90.628695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479500416, states[0] = -38.004201, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1491214217, states[0] = -85.314266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502895536, states[0] = 10.237856, states[40]= 0.007710
Saving checkpoint... 
Iteration: 1514421318, states[0] = -85.863302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525826410, states[0] = 5.322182, states[40]= 0.003203
Saving checkpoint... 
Iteration: 1537316995, states[0] = -90.447346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548775660, states[0] = -90.946205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560219618, states[0] = -79.625109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571627844, states[0] = -90.223222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583026021, states[0] = 25.585655, states[40]= 0.000980
Saving checkpoint... 
Iteration: 1594420269, states[0] = -89.273652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605766062, states[0] = -83.812642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617250968, states[0] = -88.803399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628595084, states[0] = -88.277419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639932031, states[0] = -87.668805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651265147, states[0] = -87.900921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662586469, states[0] = 8.627708, states[40]= 0.003579
Saving checkpoint... 
Iteration: 1673893695, states[0] = -87.652295, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -87.174104
 - CaMKt in component CaMK (millimolar): 0.001109
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.140654
 - nass in component intracellular_ions (millimolar): 6.140739
 - ki in component intracellular_ions (millimolar): 145.756660
 - kss in component intracellular_ions (millimolar): 145.756648
 - cansr in component intracellular_ions (millimolar): 1.551329
 - cajsr in component intracellular_ions (millimolar): 1.551426
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.007883
 - hf in component INa (dimensionless): 0.673193
 - hs in component INa (dimensionless): 0.673204
 - j in component INa (dimensionless): 0.673257
 - hsp in component INa (dimensionless): 0.426556
 - jp in component INa (dimensionless): 0.673287
 - mL in component INaL (dimensionless): 0.000215
 - hL in component INaL (dimensionless): 0.490044
 - hLp in component INaL (dimensionless): 0.296877
 - a in component Ito (dimensionless): 0.001050
 - iF in component Ito (dimensionless): 0.999496
 - iS in component Ito (dimensionless): 0.995303
 - ap in component Ito (dimensionless): 0.000535
 - iFp in component Ito (dimensionless): 0.999496
 - iSp in component Ito (dimensionless): 0.997547
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998850
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002878
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.007825
 - xs1 in component IKs (dimensionless): 0.023935
 - xs2 in component IKs (dimensionless): 0.000209
 - xk1 in component IK1 (dimensionless): 0.998760
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:34:02 (59019): called boinc_finish(0)

</stderr_txt>
]]>


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