𝕏

Task 54997248

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_666-conf_451_0
Workunit 26114494
Created 27 Jun 2024, 17:50:39 UTC
Sent 27 Jun 2024, 22:55:54 UTC
Report deadline 30 Jun 2024, 22:55:58 UTC
Received 28 Jun 2024, 7:54:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 17 min 31 sec
CPU time 2 hours 12 min 43 sec
Validate state Valid
Credit 42.78
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.52 MB
Peak swap size 2.35 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_666-conf_451.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_666-conf_451_0_r1620732149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_666-conf_451_0_r1620732149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.302946
     * GNaL_b in INaL: 0.005924
     * Gto_b in Ito: 0.075587
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032138
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.179711
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 68.702074
     * GKb_b in IKb: 0.003762
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022866
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11135160, states[0] = -58.148211, states[40]= 0.000012
Saving checkpoint... 
Iteration: 22214593, states[0] = -84.419141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33377472, states[0] = 22.557072, states[40]= 0.000008
Saving checkpoint... 
Iteration: 44486864, states[0] = -79.526509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55598636, states[0] = -84.633411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66766429, states[0] = -14.967135, states[40]= 0.000183
Saving checkpoint... 
Iteration: 77935699, states[0] = -84.643977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89089113, states[0] = -2.834660, states[40]= 0.000227
Saving checkpoint... 
Iteration: 100209804, states[0] = -84.367030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111353455, states[0] = 32.162376, states[40]= 0.012207
Saving checkpoint... 
Iteration: 122502324, states[0] = -83.840986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133615333, states[0] = -84.674074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144682416, states[0] = 31.070460, states[40]= 0.106049
Saving checkpoint... 
Iteration: 155726476, states[0] = 17.663599, states[40]= 0.000017
Saving checkpoint... 
Iteration: 166927742, states[0] = -84.603197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178135452, states[0] = -48.596472, states[40]= 0.000029
Saving checkpoint... 
Iteration: 189307140, states[0] = -84.725460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200535394, states[0] = -84.275780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211669307, states[0] = -84.772682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222854626, states[0] = -84.148096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234027450, states[0] = 32.122374, states[40]= 0.007962
Saving checkpoint... 
Iteration: 245147776, states[0] = -59.134356, states[40]= 0.000008
Saving checkpoint... 
Iteration: 256335834, states[0] = -84.768222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267508536, states[0] = -83.766471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278707104, states[0] = 29.476359, states[40]= 0.000175
Saving checkpoint... 
Iteration: 289889196, states[0] = -84.384754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301061906, states[0] = 20.311902, states[40]= 0.000010
Saving checkpoint... 
Iteration: 312078191, states[0] = 11.908369, states[40]= 0.000048
Saving checkpoint... 
Iteration: 323304133, states[0] = -84.701530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334480073, states[0] = -52.547318, states[40]= 0.000018
Saving checkpoint... 
Iteration: 345673504, states[0] = -84.765978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356532427, states[0] = -84.185228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367665526, states[0] = -84.751102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378859440, states[0] = -84.113606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390041452, states[0] = 30.973519, states[40]= 0.000874
Saving checkpoint... 
Iteration: 401180840, states[0] = -83.664616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412353871, states[0] = -84.778936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423546838, states[0] = -84.272696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434741071, states[0] = 17.326457, states[40]= 0.000019
Saving checkpoint... 
Iteration: 445954458, states[0] = -84.638993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 457146032, states[0] = -44.831787, states[40]= 0.000044
Saving checkpoint... 
Iteration: 468155459, states[0] = -54.923502, states[40]= 0.000013
Saving checkpoint... 
Iteration: 479204363, states[0] = -84.174755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490381481, states[0] = 30.467571, states[40]= 0.000482
Saving checkpoint... 
Iteration: 501530995, states[0] = -84.096354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512669442, states[0] = -84.742069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523801578, states[0] = -29.029353, states[40]= 0.000145
Saving checkpoint... 
Iteration: 534979786, states[0] = -84.692824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546081977, states[0] = 16.266649, states[40]= 0.000023
Saving checkpoint... 
Iteration: 557229233, states[0] = -84.334452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568384191, states[0] = 30.835085, states[40]= 0.000735
Saving checkpoint... 
Iteration: 579563682, states[0] = -84.334035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590764991, states[0] = 8.274298, states[40]= 0.000081
Saving checkpoint... 
Iteration: 601907832, states[0] = -84.395858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613078188, states[0] = 19.969248, states[40]= 0.000011
Saving checkpoint... 
Iteration: 624082665, states[0] = 17.957577, states[40]= 0.000017
Saving checkpoint... 
Iteration: 635241508, states[0] = -84.386947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646432709, states[0] = 9.315145, states[40]= 0.000070
Saving checkpoint... 
Iteration: 657641705, states[0] = -84.662727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668831652, states[0] = -54.313759, states[40]= 0.000014
Saving checkpoint... 
Iteration: 680001507, states[0] = -84.720459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691168827, states[0] = -57.571223, states[40]= 0.000009
Saving checkpoint... 
Iteration: 702329901, states[0] = -84.707568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713501803, states[0] = -55.791684, states[40]= 0.000012
Saving checkpoint... 
Iteration: 724678486, states[0] = -84.734363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735737250, states[0] = 26.503344, states[40]= 0.000016
Saving checkpoint... 
Iteration: 746922580, states[0] = -84.436010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758109727, states[0] = 6.401102, states[40]= 0.000103
Saving checkpoint... 
Iteration: 769276762, states[0] = -84.532265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780286967, states[0] = -84.571216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 791447589, states[0] = 4.555795, states[40]= 0.000128
Saving checkpoint... 
Iteration: 802501758, states[0] = -50.562420, states[40]= 0.000023
Saving checkpoint... 
Iteration: 813597429, states[0] = -84.460545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824748882, states[0] = 23.196082, states[40]= 0.000006
Saving checkpoint... 
Iteration: 835918418, states[0] = -84.383650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847028267, states[0] = -84.748726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858210425, states[0] = -84.004097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869341643, states[0] = -84.710713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880493393, states[0] = -37.003366, states[40]= 0.000094
Saving checkpoint... 
Iteration: 891652235, states[0] = -84.653985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902801476, states[0] = -7.611355, states[40]= 0.000236
Saving checkpoint... 
Iteration: 913975821, states[0] = -84.621629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925104513, states[0] = 14.332793, states[40]= 0.000032
Saving checkpoint... 
Iteration: 936110983, states[0] = 11.003963, states[40]= 0.000055
Saving checkpoint... 
Iteration: 947234135, states[0] = -84.216585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958375971, states[0] = -84.759171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969523455, states[0] = -67.205377, states[40]= 0.000002
Saving checkpoint... 
Iteration: 980526438, states[0] = -70.673400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991636795, states[0] = -84.588037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002772641, states[0] = 15.648942, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1013930685, states[0] = -84.399489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025056856, states[0] = 30.612872, states[40]= 0.296914
Saving checkpoint... 
Iteration: 1036233144, states[0] = -84.169401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047337807, states[0] = -84.678552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058437421, states[0] = 18.114677, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1069591333, states[0] = -84.343493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080765894, states[0] = 21.148369, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1091782013, states[0] = 12.948474, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1102914801, states[0] = -84.261540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113921932, states[0] = -84.308920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125042419, states[0] = -84.742705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136096314, states[0] = 23.895433, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1147137565, states[0] = 0.696984, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1158291622, states[0] = -84.502779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169456283, states[0] = 10.832172, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1180553700, states[0] = -83.697599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191689274, states[0] = -84.699487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202811280, states[0] = -2.705271, states[40]= 0.000224
Saving checkpoint... 
Iteration: 1213959141, states[0] = -84.492574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225113744, states[0] = 17.428998, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1236268514, states[0] = -84.353711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247256100, states[0] = -84.263678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258394615, states[0] = -84.757240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269542749, states[0] = -73.330782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280671759, states[0] = -84.645157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291827608, states[0] = -15.012486, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1302966101, states[0] = -84.502065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314126429, states[0] = 12.972155, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1325287109, states[0] = -84.434684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336455334, states[0] = 16.004113, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1347611833, states[0] = -84.378379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358765065, states[0] = 27.932321, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1369862129, states[0] = -49.032581, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1380989998, states[0] = -84.580275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392180475, states[0] = -31.354199, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1403211351, states[0] = -66.536274, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1414510629, states[0] = -26.624899, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1425718684, states[0] = -84.726843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436901469, states[0] = -83.812605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448088238, states[0] = 32.126909, states[40]= 0.007710
Saving checkpoint... 
Iteration: 1459262302, states[0] = -84.224787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470388756, states[0] = -84.727730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481590261, states[0] = -84.171551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492789426, states[0] = 19.681330, states[40]= 0.000012
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.629498
 - CaMKt in component CaMK (millimolar): 0.039465
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.860243
 - nass in component intracellular_ions (millimolar): 6.860399
 - ki in component intracellular_ions (millimolar): 144.795309
 - kss in component intracellular_ions (millimolar): 144.795281
 - cansr in component intracellular_ions (millimolar): 2.051968
 - cajsr in component intracellular_ions (millimolar): 1.799162
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010177
 - hf in component INa (dimensionless): 0.575559
 - hs in component INa (dimensionless): 0.575418
 - j in component INa (dimensionless): 0.574646
 - hsp in component INa (dimensionless): 0.328263
 - jp in component INa (dimensionless): 0.574009
 - mL in component INaL (dimensionless): 0.000349
 - hL in component INaL (dimensionless): 0.349558
 - hLp in component INaL (dimensionless): 0.153226
 - a in component Ito (dimensionless): 0.001246
 - iF in component Ito (dimensionless): 0.999212
 - iS in component Ito (dimensionless): 0.366885
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999212
 - iSp in component Ito (dimensionless): 0.401666
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842188
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995683
 - jca in component ICaL (dimensionless): 0.998112
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005901
 - xrf in component IKr (dimensionless): 0.000383
 - xrs in component IKr (dimensionless): 0.673147
 - xs1 in component IKs (dimensionless): 0.386271
 - xs2 in component IKs (dimensionless): 0.000279
 - xk1 in component IK1 (dimensionless): 0.996769
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:49:25 (61047): called boinc_finish(0)

</stderr_txt>
]]>


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