𝕏

Task 54997200

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_400-conf_951_0
Workunit 26114470
Created 27 Jun 2024, 17:50:38 UTC
Sent 27 Jun 2024, 22:55:54 UTC
Report deadline 30 Jun 2024, 22:55:54 UTC
Received 28 Jun 2024, 5:15:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 13 min 29 sec
CPU time 2 hours 11 min 22 sec
Validate state Valid
Credit 41.70
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.49 MB
Peak swap size 2.35 GB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_400-conf_951.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_400-conf_951_0_r1111433442_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Schmidt_400-conf_951_0_r1111433442_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.192100
     * GNaL_b in INaL: 0.005488
     * Gto_b in Ito: 0.083978
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033409
     * GKs_b in IKs: 0.001761
     * GK1_b in IK1: 0.155332
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 68.110955
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027631
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11642487, states[0] = 19.585057, states[40]= 0.000084
Saving checkpoint... 
Iteration: 23084050, states[0] = -15.481720, states[40]= 0.000262
Saving checkpoint... 
Iteration: 34766154, states[0] = -84.659260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 46430487, states[0] = 26.222730, states[40]= 0.000036
Saving checkpoint... 
Iteration: 58110992, states[0] = -52.904431, states[40]= 0.000028
Saving checkpoint... 
Iteration: 69770115, states[0] = -84.753760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81425035, states[0] = 28.397074, states[40]= 0.000248
Saving checkpoint... 
Iteration: 93059371, states[0] = 8.518223, states[40]= 0.000025
Saving checkpoint... 
Iteration: 104696458, states[0] = -35.385618, states[40]= 0.000096
Saving checkpoint... 
Iteration: 116355594, states[0] = -84.593989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127870700, states[0] = -1.446908, states[40]= 0.000094
Saving checkpoint... 
Iteration: 139527587, states[0] = -76.736983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151159988, states[0] = -84.656120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162810656, states[0] = 30.029264, states[40]= 0.052844
Saving checkpoint... 
Iteration: 174429702, states[0] = 26.272750, states[40]= 0.000045
Saving checkpoint... 
Iteration: 186072148, states[0] = -3.066934, states[40]= 0.000104
Saving checkpoint... 
Iteration: 197652603, states[0] = 13.176831, states[40]= 0.000008
Saving checkpoint... 
Iteration: 209309627, states[0] = -52.462961, states[40]= 0.000025
Saving checkpoint... 
Iteration: 220963749, states[0] = -84.699878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232606769, states[0] = 28.722057, states[40]= 0.228211
Saving checkpoint... 
Iteration: 244258105, states[0] = 9.339946, states[40]= 0.000019
Saving checkpoint... 
Iteration: 255881038, states[0] = -14.646409, states[40]= 0.000106
Saving checkpoint... 
Iteration: 267463499, states[0] = 5.160366, states[40]= 0.000042
Saving checkpoint... 
Iteration: 279025847, states[0] = 27.981673, states[40]= 0.000182
Saving checkpoint... 
Iteration: 290660106, states[0] = 7.847594, states[40]= 0.000026
Saving checkpoint... 
Iteration: 302262825, states[0] = 5.712561, states[40]= 0.000038
Saving checkpoint... 
Iteration: 313859596, states[0] = 8.234607, states[40]= 0.000024
Saving checkpoint... 
Iteration: 325481171, states[0] = -14.830074, states[40]= 0.000105
Saving checkpoint... 
Iteration: 337081158, states[0] = -14.810872, states[40]= 0.000105
Saving checkpoint... 
Iteration: 348674110, states[0] = -5.353154, states[40]= 0.000115
Saving checkpoint... 
Iteration: 360363534, states[0] = -84.689531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371983911, states[0] = -84.893961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383613129, states[0] = 30.551843, states[40]= 0.020518
Saving checkpoint... 
Iteration: 395217030, states[0] = 30.537408, states[40]= 0.004687
Saving checkpoint... 
Iteration: 406787490, states[0] = -84.921458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 418385159, states[0] = -84.901826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430021350, states[0] = 29.604283, states[40]= 0.000941
Saving checkpoint... 
Iteration: 441629041, states[0] = 26.583888, states[40]= 0.000057
Saving checkpoint... 
Iteration: 453226659, states[0] = 27.645101, states[40]= 0.000135
Saving checkpoint... 
Iteration: 464819558, states[0] = 30.085043, states[40]= 0.001825
Saving checkpoint... 
Iteration: 476437535, states[0] = 22.265357, states[40]= 0.000003
Saving checkpoint... 
Iteration: 488046955, states[0] = 16.798644, states[40]= 0.000003
Saving checkpoint... 
Iteration: 499645781, states[0] = 17.516396, states[40]= 0.000003
Saving checkpoint... 
Iteration: 511276520, states[0] = -8.398987, states[40]= 0.000120
Saving checkpoint... 
Iteration: 522878896, states[0] = -11.622577, states[40]= 0.000115
Saving checkpoint... 
Iteration: 534291988, states[0] = -29.713074, states[40]= 0.000104
Saving checkpoint... 
Iteration: 545876967, states[0] = -8.989905, states[40]= 0.000120
Saving checkpoint... 
Iteration: 557471589, states[0] = -2.438640, states[40]= 0.000099
Saving checkpoint... 
Iteration: 569094121, states[0] = -32.530711, states[40]= 0.000101
Saving checkpoint... 
Iteration: 580731856, states[0] = -80.950281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592313061, states[0] = -56.864003, states[40]= 0.000016
Saving checkpoint... 
Iteration: 603922164, states[0] = -69.326587, states[40]= 0.000004
Saving checkpoint... 
Iteration: 615435593, states[0] = 23.313896, states[40]= 0.000006
Saving checkpoint... 
Iteration: 627033514, states[0] = 24.398989, states[40]= 0.000012
Saving checkpoint... 
Iteration: 638635730, states[0] = 23.241646, states[40]= 0.000005
Saving checkpoint... 
Iteration: 650253247, states[0] = 12.754815, states[40]= 0.000009
Saving checkpoint... 
Iteration: 661864983, states[0] = 3.925166, states[40]= 0.000050
Saving checkpoint... 
Iteration: 673510028, states[0] = -52.938493, states[40]= 0.000024
Saving checkpoint... 
Iteration: 685154452, states[0] = -84.549068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696754032, states[0] = -84.541697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708368499, states[0] = -84.726407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719959156, states[0] = -84.614345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731544992, states[0] = -84.305244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743159166, states[0] = -84.613154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754703660, states[0] = -44.814047, states[40]= 0.000051
Saving checkpoint... 
Iteration: 766286846, states[0] = -22.744405, states[40]= 0.000096
Saving checkpoint... 
Iteration: 777910223, states[0] = -53.178428, states[40]= 0.000023
Saving checkpoint... 
Iteration: 789511173, states[0] = -54.398098, states[40]= 0.000021
Saving checkpoint... 
Iteration: 801115713, states[0] = -60.340339, states[40]= 0.000011
Saving checkpoint... 
Iteration: 812782576, states[0] = -84.857785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824419459, states[0] = 30.115285, states[40]= 0.001893
Saving checkpoint... 
Iteration: 836028985, states[0] = 26.618466, states[40]= 0.000058
Saving checkpoint... 
Iteration: 847644683, states[0] = 18.185845, states[40]= 0.000002
Saving checkpoint... 
Iteration: 859188270, states[0] = -84.902325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870812334, states[0] = 30.438368, states[40]= 0.027781
Saving checkpoint... 
Iteration: 882414984, states[0] = 30.672482, states[40]= 0.010130
Saving checkpoint... 
Iteration: 893943707, states[0] = -84.227626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905536312, states[0] = -83.128253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917126997, states[0] = -75.954517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928772570, states[0] = -84.756954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940253532, states[0] = 12.570188, states[40]= 0.000009
Saving checkpoint... 
Iteration: 951851763, states[0] = 13.750116, states[40]= 0.000007
Saving checkpoint... 
Iteration: 962959064, states[0] = -84.599273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974035415, states[0] = 23.416255, states[40]= 0.000006
Saving checkpoint... 
Iteration: 985142791, states[0] = -84.161819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996276017, states[0] = -7.709412, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1007350669, states[0] = -84.462476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018380398, states[0] = -84.827000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029479758, states[0] = -12.788578, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1040628146, states[0] = 27.005759, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1051744681, states[0] = -84.270417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062803429, states[0] = 31.269845, states[40]= 0.747162
Saving checkpoint... 
Iteration: 1073917846, states[0] = -63.194542, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1085038200, states[0] = 21.914484, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1096144700, states[0] = -84.268574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107297676, states[0] = -37.120237, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1118285420, states[0] = -20.745285, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1129488218, states[0] = -24.594733, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1140689641, states[0] = -26.522752, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1151895529, states[0] = -34.329114, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1163058938, states[0] = 8.752102, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1174181819, states[0] = -84.830883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185355841, states[0] = -84.541574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196467412, states[0] = 1.781225, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1207663812, states[0] = 4.933197, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1218780536, states[0] = -84.816978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229900434, states[0] = -40.656796, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1241083122, states[0] = -17.517318, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1252284623, states[0] = -19.623927, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1263462329, states[0] = 6.143606, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1274475929, states[0] = -7.577613, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1285598098, states[0] = -84.950165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296679329, states[0] = -12.169608, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1307730787, states[0] = -79.996689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318715403, states[0] = -59.867806, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1329812438, states[0] = 30.463921, states[40]= 0.026682
Saving checkpoint... 
Iteration: 1340925124, states[0] = -73.394953, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1352042220, states[0] = 19.647888, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1363201640, states[0] = 34.695065, states[40]= 1.266959
Saving checkpoint... 
Iteration: 1374324446, states[0] = -72.447456, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1385440257, states[0] = 20.772958, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1396534777, states[0] = -82.521632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407617044, states[0] = 30.554894, states[40]= 0.004658
Saving checkpoint... 
Iteration: 1418675686, states[0] = -7.255536, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1429612869, states[0] = 30.533881, states[40]= 0.022629
Saving checkpoint... 
Iteration: 1440650331, states[0] = 14.695202, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1451691442, states[0] = -28.914827, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1462839379, states[0] = 21.268622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1473819144, states[0] = 30.198834, states[40]= 0.002127
Saving checkpoint... 
Iteration: 1484909005, states[0] = -51.553189, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1496044249, states[0] = 18.459822, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.826491
 - CaMKt in component CaMK (millimolar): 0.154284
 - cass in component intracellular_ions (millimolar): 0.000144
 - nai in component intracellular_ions (millimolar): 7.233727
 - nass in component intracellular_ions (millimolar): 7.233999
 - ki in component intracellular_ions (millimolar): 143.994079
 - kss in component intracellular_ions (millimolar): 143.994043
 - cansr in component intracellular_ions (millimolar): 2.977733
 - cajsr in component intracellular_ions (millimolar): 1.942877
 - cai in component intracellular_ions (millimolar): 0.000138
 - m in component INa (dimensionless): 0.009978
 - hf in component INa (dimensionless): 0.583440
 - hs in component INa (dimensionless): 0.582736
 - j in component INa (dimensionless): 0.575005
 - hsp in component INa (dimensionless): 0.333637
 - jp in component INa (dimensionless): 0.558785
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.239618
 - hLp in component INaL (dimensionless): 0.098848
 - a in component Ito (dimensionless): 0.001230
 - iF in component Ito (dimensionless): 0.999236
 - iS in component Ito (dimensionless): 0.183191
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999237
 - iSp in component Ito (dimensionless): 0.204335
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.728690
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.958904
 - jca in component ICaL (dimensionless): 0.958169
 - ffp in component ICaL (dimensionless): 0.999946
 - fcafp in component ICaL (dimensionless): 0.999998
 - nca in component ICaL (dimensionless): 0.020956
 - xrf in component IKr (dimensionless): 0.034233
 - xrs in component IKr (dimensionless): 0.830298
 - xs1 in component IKs (dimensionless): 0.521647
 - xs2 in component IKs (dimensionless): 0.001382
 - xk1 in component IK1 (dimensionless): 0.996730
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:10:31 (59801): called boinc_finish(0)

</stderr_txt>
]]>