𝕏

Task 54994945

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_349_1
Workunit 26113343
Created 27 Jun 2024, 17:49:29 UTC
Sent 27 Jun 2024, 22:32:13 UTC
Report deadline 1 Jul 2024, 8:08:13 UTC
Received 30 Jun 2024, 13:48:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 59 min 20 sec
CPU time 2 hours 2 min 24 sec
Validate state Valid
Credit 58.35
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.32 MB
Peak swap size 5.40 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_349.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_349_1_r47958915_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_349_1_r47958915_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.115494
     * GNaL_b in INaL: 0.004601
     * Gto_b in Ito: 0.089397
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033793
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.155559
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 68.286229
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024922
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11053715, states[0] = 6.623407, states[40]= 0.004829
Saving checkpoint... 
Iteration: 24580787, states[0] = -10.036190, states[40]= 0.002382
Saving checkpoint... 
Iteration: 38145737, states[0] = -84.076122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51760875, states[0] = -94.931173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63076993, states[0] = -5.423846, states[40]= 0.003362
Saving checkpoint... 
Iteration: 76377390, states[0] = -95.000891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88917807, states[0] = -95.010404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102972418, states[0] = -95.019090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115751472, states[0] = -94.901048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128486173, states[0] = -95.018623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138819098, states[0] = -94.962941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151887153, states[0] = -94.995251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164930703, states[0] = -95.007201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178702260, states[0] = -94.815611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190199196, states[0] = -94.808957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204590717, states[0] = -17.506049, states[40]= 0.001177
Saving checkpoint... 
Iteration: 217680106, states[0] = -94.763964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231265842, states[0] = -94.915151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237591718, states[0] = -18.517824, states[40]= 0.001076
Saving checkpoint... 
Iteration: 248587327, states[0] = -14.080009, states[40]= 0.001626
Saving checkpoint... 
Iteration: 260327225, states[0] = -94.966389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275112096, states[0] = -39.440769, states[40]= 0.000129
Saving checkpoint... 
Iteration: 287775547, states[0] = -94.925384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301446752, states[0] = -95.009779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313859297, states[0] = -94.983082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328059180, states[0] = 5.515819, states[40]= 0.004783
Saving checkpoint... 
Iteration: 341388521, states[0] = -94.994472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355444972, states[0] = -95.009378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369108112, states[0] = -35.296534, states[40]= 0.000228
Saving checkpoint... 
Iteration: 382672689, states[0] = -94.734867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397591301, states[0] = -18.087484, states[40]= 0.001117
Saving checkpoint... 
Iteration: 412064404, states[0] = 2.945226, states[40]= 0.004607
Saving checkpoint... 
Iteration: 422971218, states[0] = -95.014014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435211000, states[0] = -94.832553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447349652, states[0] = -94.978474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460394438, states[0] = -94.996347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474443856, states[0] = -95.009074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487641416, states[0] = -73.685235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500321610, states[0] = -94.962682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512888317, states[0] = -94.994290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526255675, states[0] = -94.902832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539116525, states[0] = -44.145970, states[40]= 0.000064
Saving checkpoint... 
Iteration: 553818270, states[0] = -94.960469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566660170, states[0] = -94.193445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578913509, states[0] = -95.001887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591822810, states[0] = -94.963389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603603457, states[0] = -30.513168, states[40]= 0.000404
Saving checkpoint... 
Iteration: 616748741, states[0] = -94.893828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628993074, states[0] = -95.016990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641503784, states[0] = 32.678296, states[40]= 0.149870
Saving checkpoint... 
Iteration: 652114743, states[0] = -42.236733, states[40]= 0.000085
Saving checkpoint... 
Iteration: 663624145, states[0] = -52.504427, states[40]= 0.000017
Saving checkpoint... 
Iteration: 675447128, states[0] = -95.009602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687886976, states[0] = -94.993720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701249048, states[0] = -94.894184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714856069, states[0] = -94.981353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728630383, states[0] = -59.539187, states[40]= 0.000005
Saving checkpoint... 
Iteration: 741737961, states[0] = -94.878512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755429168, states[0] = -95.005699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769001655, states[0] = 48.910168, states[40]= 0.062394
Saving checkpoint... 
Iteration: 780190228, states[0] = -94.788295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793068042, states[0] = 0.980583, states[40]= 0.004413
Saving checkpoint... 
Iteration: 803570718, states[0] = -0.590455, states[40]= 0.004213
Saving checkpoint... 
Iteration: 817904849, states[0] = -94.999309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830557265, states[0] = 6.403608, states[40]= 0.004829
Saving checkpoint... 
Iteration: 840642694, states[0] = -75.633108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854649804, states[0] = -87.102461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867372795, states[0] = -94.988383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880757001, states[0] = -94.904246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894039347, states[0] = 13.860608, states[40]= 0.005323
Saving checkpoint... 
Iteration: 906646032, states[0] = -81.061011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920846816, states[0] = -94.976766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933511481, states[0] = 21.699136, states[40]= 0.038987
Saving checkpoint... 
Iteration: 947284836, states[0] = -94.933947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957262444, states[0] = -94.910697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968587078, states[0] = -13.828905, states[40]= 0.001666
Saving checkpoint... 
Iteration: 981550393, states[0] = 9.418054, states[40]= 0.004966
Saving checkpoint... 
Iteration: 993322581, states[0] = -94.962990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006068356, states[0] = 0.802454, states[40]= 0.004392
Saving checkpoint... 
Iteration: 1018684570, states[0] = -94.774790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031405700, states[0] = -94.999421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046053498, states[0] = 8.084910, states[40]= 0.004906
Saving checkpoint... 
Iteration: 1058872469, states[0] = -94.988133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071417019, states[0] = -95.002505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085113961, states[0] = -41.405185, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1099811426, states[0] = -94.955430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112241573, states[0] = -94.883570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124078205, states[0] = -5.799383, states[40]= 0.003275
Saving checkpoint... 
Iteration: 1135404971, states[0] = -94.999144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146871425, states[0] = -94.987663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160533641, states[0] = 15.955638, states[40]= 0.005732
Saving checkpoint... 
Iteration: 1173112703, states[0] = -40.076075, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1185449877, states[0] = -95.009814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199377808, states[0] = -94.990099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211535503, states[0] = 15.292700, states[40]= 0.005571
Saving checkpoint... 
Iteration: 1224108586, states[0] = -35.785414, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1237329739, states[0] = -94.967230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252304385, states[0] = -94.950163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265052904, states[0] = 8.343347, states[40]= 0.004917
Saving checkpoint... 
Iteration: 1277000986, states[0] = 50.429327, states[40]= 0.023448
Saving checkpoint... 
Iteration: 1290232567, states[0] = -94.869887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302423727, states[0] = -95.004054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313915402, states[0] = -95.001927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325531853, states[0] = 16.570151, states[40]= 0.005919
Saving checkpoint... 
Iteration: 1337662435, states[0] = -94.453758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350138390, states[0] = -69.391942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363371112, states[0] = -94.987401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375156016, states[0] = -92.988246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386700376, states[0] = -94.810328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399609387, states[0] = -36.614309, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1412838386, states[0] = -94.972038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425602935, states[0] = -29.977977, states[40]= 0.000428
Saving checkpoint... 
Iteration: 1437515990, states[0] = 20.764229, states[40]= 0.016218
Saving checkpoint... 
Iteration: 1451139856, states[0] = -71.417199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463014689, states[0] = 21.013089, states[40]= 0.020210
Saving checkpoint... 
Iteration: 1474101322, states[0] = -28.327075, states[40]= 0.000502
Saving checkpoint... 
Iteration: 1485690777, states[0] = -94.789101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495142455, states[0] = -75.261212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507406945, states[0] = -95.155009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521315325, states[0] = 21.443300, states[40]= 0.020040
Saving checkpoint... 
Iteration: 1531651565, states[0] = -95.034581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543500641, states[0] = 42.044792, states[40]= 0.002728
Saving checkpoint... 
Iteration: 1557575709, states[0] = -95.285304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573172621, states[0] = -95.288047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585153622, states[0] = -95.272390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596253590, states[0] = -95.274058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609827250, states[0] = 16.922598, states[40]= 0.007704
Saving checkpoint... 
Iteration: 1620912361, states[0] = 22.066441, states[40]= 0.033614
Saving checkpoint... 
Iteration: 1634484239, states[0] = -27.668970, states[40]= 0.000538
Saving checkpoint... 
Iteration: 1644701999, states[0] = -48.966614, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1657809448, states[0] = 23.309394, states[40]= 0.061883
Saving checkpoint... 
Iteration: 1669823123, states[0] = 18.530704, states[40]= 0.009129
Saving checkpoint... 
Iteration: 1681253875, states[0] = 2.820383, states[40]= 0.005196
Saving checkpoint... 
Iteration: 1694611889, states[0] = -95.221419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708331725, states[0] = -91.651329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720200781, states[0] = 46.808845, states[40]= 0.008675
Saving checkpoint... 
Iteration: 1733747240, states[0] = 6.886263, states[40]= 0.005615
Saving checkpoint... 
Iteration: 1746667503, states[0] = -8.365372, states[40]= 0.003052
Saving checkpoint... 
Iteration: 1759281711, states[0] = -24.740731, states[40]= 0.000696
Saving checkpoint... 
Iteration: 1772865724, states[0] = -95.120332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786943050, states[0] = -94.937177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800061696, states[0] = -0.443588, states[40]= 0.004714
Saving checkpoint... 
Iteration: 1811416751, states[0] = -95.056683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824541706, states[0] = 12.401705, states[40]= 0.005209
Saving checkpoint... 
Iteration: 1836611144, states[0] = -40.105625, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1847571776, states[0] = -1.848978, states[40]= 0.004036
Saving checkpoint... 
Iteration: 1858592551, states[0] = -20.146697, states[40]= 0.000942
Saving checkpoint... 
Iteration: 1871217887, states[0] = -94.854819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884697974, states[0] = -94.811740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897666768, states[0] = -94.669685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909304165, states[0] = -94.952823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923444296, states[0] = -95.010358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936828419, states[0] = -94.967420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949293023, states[0] = -94.941554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961160004, states[0] = -94.174240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974517898, states[0] = 20.383197, states[40]= 0.012404
Saving checkpoint... 
Iteration: 1987818922, states[0] = -94.960272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997683579, states[0] = -94.771924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010770147, states[0] = -94.918748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022431171, states[0] = -95.005427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033564610, states[0] = 2.836858, states[40]= 0.004598
Saving checkpoint... 
Iteration: 2048011267, states[0] = 21.756132, states[40]= 0.040917
Saving checkpoint... 
Iteration: 2061613838, states[0] = -41.276452, states[40]= 0.000098
Saving checkpoint... 
Iteration: 2074112257, states[0] = -39.608138, states[40]= 0.000125
Saving checkpoint... 
Iteration: 2087251127, states[0] = -94.896007, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892751
 - CaMKt in component CaMK (millimolar): 0.006803
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.639509
 - nass in component intracellular_ions (millimolar): 6.639569
 - ki in component intracellular_ions (millimolar): 145.338886
 - kss in component intracellular_ions (millimolar): 145.338866
 - cansr in component intracellular_ions (millimolar): 1.308180
 - cajsr in component intracellular_ions (millimolar): 1.271194
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879843
 - hs in component INa (dimensionless): 0.879838
 - j in component INa (dimensionless): 0.879808
 - hsp in component INa (dimensionless): 0.725532
 - jp in component INa (dimensionless): 0.879788
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711640
 - hLp in component INaL (dimensionless): 0.457761
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.630785
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.707814
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.942902
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999909
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.322144
 - xs1 in component IKs (dimensionless): 0.225032
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:48:23 (18052): called boinc_finish(0)

</stderr_txt>
]]>


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