𝕏

Task 54994942

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_249_0
Workunit 26113342
Created 27 Jun 2024, 17:49:29 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 1 Jul 2024, 8:08:22 UTC
Received 29 Jun 2024, 1:09:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 3 hours 12 min 44 sec
CPU time 2 hours 32 min 40 sec
Validate state Valid
Credit 56.59
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.26 MB
Peak swap size 5.28 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_249.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_249_0_r478760052_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_249_0_r478760052_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.551448
     * GNaL_b in INaL: 0.004576
     * Gto_b in Ito: 0.071411
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033859
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.157040
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.228824
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036114
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8741671, states[0] = -95.121546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17008157, states[0] = 24.761981, states[40]= 0.077090
Saving checkpoint... 
Iteration: 23628794, states[0] = -65.157428, states[40]= 0.000002
Saving checkpoint... 
Iteration: 32349061, states[0] = -95.110959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39715401, states[0] = -94.969798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48612791, states[0] = -43.052347, states[40]= 0.000073
Saving checkpoint... 
Iteration: 57123839, states[0] = -55.003169, states[40]= 0.000011
Saving checkpoint... 
Iteration: 65050827, states[0] = 9.405210, states[40]= 0.005125
Saving checkpoint... 
Iteration: 73068618, states[0] = 0.487204, states[40]= 0.004430
Saving checkpoint... 
Iteration: 81911811, states[0] = -95.079449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89787077, states[0] = -95.015628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98263291, states[0] = -94.990354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106032931, states[0] = 17.167387, states[40]= 0.006110
Saving checkpoint... 
Iteration: 115122270, states[0] = -51.465660, states[40]= 0.000019
Saving checkpoint... 
Iteration: 124036559, states[0] = 15.790243, states[40]= 0.005763
Saving checkpoint... 
Iteration: 132108143, states[0] = -35.810493, states[40]= 0.000208
Saving checkpoint... 
Iteration: 140868774, states[0] = -95.053894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148527243, states[0] = 19.270530, states[40]= 0.007038
Saving checkpoint... 
Iteration: 156228185, states[0] = -94.937435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164633609, states[0] = -64.543314, states[40]= 0.000002
Saving checkpoint... 
Iteration: 172801625, states[0] = -95.016400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180479467, states[0] = -95.078430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187657217, states[0] = -93.984192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195824254, states[0] = -95.030695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204277153, states[0] = -94.995539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211946690, states[0] = -95.072731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220711795, states[0] = -94.908622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227886180, states[0] = -95.057629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235810128, states[0] = -95.021478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242599063, states[0] = -26.082085, states[40]= 0.000598
Saving checkpoint... 
Iteration: 248629950, states[0] = -59.983741, states[40]= 0.000004
Saving checkpoint... 
Iteration: 255206947, states[0] = -94.899510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263330094, states[0] = -95.033539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273933279, states[0] = -95.069802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277949705, states[0] = -95.072977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286939211, states[0] = -95.070985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294030593, states[0] = 18.117726, states[40]= 0.006420
Saving checkpoint... 
Iteration: 302007210, states[0] = 26.241831, states[40]= 0.093643
Saving checkpoint... 
Iteration: 307605970, states[0] = -33.322095, states[40]= 0.000287
Saving checkpoint... 
Iteration: 315100443, states[0] = -27.520715, states[40]= 0.000530
Saving checkpoint... 
Iteration: 318920286, states[0] = -95.066856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328666805, states[0] = -94.768648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334439077, states[0] = -95.070907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345078715, states[0] = -5.918022, states[40]= 0.003281
Saving checkpoint... 
Iteration: 352460226, states[0] = -95.074694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364371235, states[0] = -95.052170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376101222, states[0] = -28.336143, states[40]= 0.000492
Saving checkpoint... 
Iteration: 388314044, states[0] = -95.023818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395387375, states[0] = -95.057729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402934836, states[0] = -95.070006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410532921, states[0] = 17.255704, states[40]= 0.006114
Saving checkpoint... 
Iteration: 414373807, states[0] = -95.053087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419899818, states[0] = -95.061476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423768493, states[0] = -94.986570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430532857, states[0] = 17.279882, states[40]= 0.006122
Saving checkpoint... 
Iteration: 440512260, states[0] = 23.541463, states[40]= 0.031559
Saving checkpoint... 
Iteration: 453561969, states[0] = 4.570470, states[40]= 0.004819
Saving checkpoint... 
Iteration: 463642430, states[0] = -77.050493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468869909, states[0] = -95.051613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476972248, states[0] = -95.076469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483411309, states[0] = -95.064547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490796577, states[0] = -95.011454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502335241, states[0] = -95.036110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514554730, states[0] = 8.045239, states[40]= 0.005030
Saving checkpoint... 
Iteration: 529120032, states[0] = -48.564886, states[40]= 0.000031
Saving checkpoint... 
Iteration: 539041555, states[0] = 13.803550, states[40]= 0.005445
Saving checkpoint... 
Iteration: 543284768, states[0] = -95.001802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552951531, states[0] = -95.073107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564171301, states[0] = -94.812398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574650013, states[0] = -89.179251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584334919, states[0] = -95.035896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588815124, states[0] = -95.024400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599013676, states[0] = 23.147617, states[40]= 0.024003
Saving checkpoint... 
Iteration: 609160485, states[0] = -94.490503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619260669, states[0] = -94.978152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625939336, states[0] = -95.070791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629735783, states[0] = -94.946800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635819477, states[0] = -95.027096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643662658, states[0] = -94.644320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648664280, states[0] = -94.710291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659566437, states[0] = 2.219709, states[40]= 0.004615
Saving checkpoint... 
Iteration: 671136312, states[0] = -67.955526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684210248, states[0] = -94.905312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698270665, states[0] = -94.988611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704105951, states[0] = -33.300743, states[40]= 0.000287
Saving checkpoint... 
Iteration: 715482165, states[0] = -95.077714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727291805, states[0] = -95.007573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733670109, states[0] = -94.804588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738122576, states[0] = -51.442121, states[40]= 0.000019
Saving checkpoint... 
Iteration: 742221485, states[0] = -94.924797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752139371, states[0] = -72.270763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761450617, states[0] = -95.072832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766523586, states[0] = 20.469709, states[40]= 0.008175
Saving checkpoint... 
Iteration: 777130157, states[0] = -60.221829, states[40]= 0.000004
Saving checkpoint... 
Iteration: 783082677, states[0] = -9.356999, states[40]= 0.002534
Saving checkpoint... 
Iteration: 790196878, states[0] = -94.879363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800819542, states[0] = -95.027046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811233761, states[0] = -94.943785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819632061, states[0] = -62.520422, states[40]= 0.000003
Saving checkpoint... 
Iteration: 829235433, states[0] = -94.946190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841491635, states[0] = -95.078842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855350532, states[0] = -95.043382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870108286, states[0] = -35.764411, states[40]= 0.000209
Saving checkpoint... 
Iteration: 883768343, states[0] = -94.986165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897981577, states[0] = -95.077537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911464905, states[0] = -95.075129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924095526, states[0] = -22.373926, states[40]= 0.000792
Saving checkpoint... 
Iteration: 937735285, states[0] = -94.945919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950459814, states[0] = -95.074297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961030565, states[0] = 18.128313, states[40]= 0.006424
Saving checkpoint... 
Iteration: 971459646, states[0] = -95.074258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981884001, states[0] = -95.056312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992243393, states[0] = -94.957050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002449125, states[0] = -95.072434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012603957, states[0] = -31.204416, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1022807645, states[0] = -95.019208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033167186, states[0] = -94.774053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041978832, states[0] = -95.077089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051333365, states[0] = -95.034817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061218601, states[0] = -94.919810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071253021, states[0] = -94.969110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081359911, states[0] = -95.047325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091397922, states[0] = -95.060565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101423275, states[0] = -95.067112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111536921, states[0] = 15.699574, states[40]= 0.005735
Saving checkpoint... 
Iteration: 1121573255, states[0] = -1.894936, states[40]= 0.004063
Saving checkpoint... 
Iteration: 1131690691, states[0] = -94.866266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141885211, states[0] = -95.056622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151731583, states[0] = -94.940392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161178874, states[0] = -94.839360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171274059, states[0] = -94.991681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181283518, states[0] = -95.000367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191652225, states[0] = -91.485991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201899079, states[0] = -95.060839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211686654, states[0] = -94.857483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221752791, states[0] = -94.968753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231822769, states[0] = -95.028754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242165327, states[0] = -94.738995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252382519, states[0] = -95.055671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261934992, states[0] = -95.069570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271387717, states[0] = -95.057361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281367714, states[0] = -95.050335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291588896, states[0] = -15.473044, states[40]= 0.001432
Saving checkpoint... 
Iteration: 1301838833, states[0] = -95.037528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311901016, states[0] = -95.061330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321818725, states[0] = -95.026261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332081428, states[0] = -8.225473, states[40]= 0.002778
Saving checkpoint... 
Iteration: 1342309236, states[0] = -95.020119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354765617, states[0] = -94.983084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367617355, states[0] = -45.571415, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1379983315, states[0] = -95.077504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391988178, states[0] = -95.078119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404795328, states[0] = -95.009991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418346343, states[0] = -95.041138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431749619, states[0] = -94.964773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444744207, states[0] = -94.957873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457909501, states[0] = -95.063550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470976073, states[0] = -95.076475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484462786, states[0] = -95.074485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497661357, states[0] = -94.563448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512620517, states[0] = 21.236734, states[40]= 0.011480
Saving checkpoint... 
Iteration: 1531517047, states[0] = 22.322450, states[40]= 0.015820
Saving checkpoint... 
Iteration: 1552364236, states[0] = -95.169094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573742277, states[0] = -95.316541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595742401, states[0] = 10.369586, states[40]= 0.006072
Saving checkpoint... 
Iteration: 1619397296, states[0] = -95.369322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647088657, states[0] = -32.258342, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1673604664, states[0] = -95.270601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700747175, states[0] = 7.597176, states[40]= 0.005762
Saving checkpoint... 
Iteration: 1726709365, states[0] = -95.278678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757493171, states[0] = -37.700296, states[40]= 0.000165
Saving checkpoint... 
Iteration: 1788029171, states[0] = 17.090958, states[40]= 0.007614
Saving checkpoint... 
Iteration: 1817491761, states[0] = -95.121761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847346045, states[0] = -95.058996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878127905, states[0] = -58.094711, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1909457544, states[0] = -95.076247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940189769, states[0] = -94.864998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974838109, states[0] = -95.037172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010543571, states[0] = 12.954022, states[40]= 0.005354
Saving checkpoint... 
Iteration: 2050919184, states[0] = -95.065641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087519105, states[0] = 21.753357, states[40]= 0.011261
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.954972
 - CaMKt in component CaMK (millimolar): 0.006452
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.383601
 - nass in component intracellular_ions (millimolar): 6.383660
 - ki in component intracellular_ions (millimolar): 145.600531
 - kss in component intracellular_ions (millimolar): 145.600511
 - cansr in component intracellular_ions (millimolar): 1.285571
 - cajsr in component intracellular_ions (millimolar): 1.248953
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003599
 - hf in component INa (dimensionless): 0.880919
 - hs in component INa (dimensionless): 0.880915
 - j in component INa (dimensionless): 0.880887
 - hsp in component INa (dimensionless): 0.727565
 - jp in component INa (dimensionless): 0.880869
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713551
 - hLp in component INaL (dimensionless): 0.460475
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.631734
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.708520
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940087
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999905
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001511
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.321307
 - xs1 in component IKs (dimensionless): 0.227044
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:09:03 (14940): called boinc_finish(0)

</stderr_txt>
]]>


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